List of works - Alfonso Bueno-Orovio

Anomalous Diffusion in Cardiac Tissue as an Index of Myocardial Microstructure

scientific article published on 2 May 2016

Atrial Fibrillation Dynamics and Ionic Block Effects in Six Heterogeneous Human 3D Virtual Atria with Distinct Repolarization Dynamics.

scientific article published on 8 May 2017

Balance between sodium and calcium currents underlying chronic atrial fibrillation termination: An in silico intersubject variability study.

scientific article published on 25 August 2016

Basis for the Induction of Tissue-Level Phase-2 Reentry as a Repolarization Disorder in the Brugada Syndrome

scientific article published on 25 October 2015

Chaste: Cancer, Heart and Soft Tissue Environment

scientific article published on 13 March 2020

Commentary: Atrial Rotor Dynamics Under Complex Fractional Order Diffusion

article

ECG-based estimation of dispersion of APD restitution as a tool to stratify sotalol-induced arrhythmic risk

scientific article

Electrophysiological and anatomical factors determine arrhythmic risk in acute myocardial ischaemia and its modulation by sodium current availability

scientific article published on 11 December 2020

Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology

scientific article published on 20 May 2013

Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization

scientific article published on August 2014

High arrhythmic risk in antero-septal acute myocardial ischemia is explained by increased transmural reentry occurrence

scientific article published on 14 November 2019

Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity

scientific article published on 12 September 2017

Human ventricular activation sequence and the simulation of the electrocardiographic QRS complex and its variability in healthy and intraventricular block conditions

scientific article published on December 2016

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop.

scientific article

In Vivo and In Silico Investigation Into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes

scientific article

In vivo human left-to-right ventricular differences in rate adaptation transiently increase pro-arrhythmic risk following rate acceleration

scientific article

Inter-subject variability in human atrial action potential in sinus rhythm versus chronic atrial fibrillation

scientific article

Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D

scientific article published on 18 March 2019

Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy

scientific article published on 15 September 2015

Minimal model for human ventricular action potentials in tissue.

scientific article published on 8 April 2008

Na/K pump regulation of cardiac repolarization: insights from a systems biology approach

scientific article published on 15 May 2013

On the Order of the Fractional Laplacian in Determining the Spatio-Temporal Evolution of a Space-Fractional Model of Cardiac Electrophysiology

scientific article published on 2 December 2015

Slow Recovery of Excitability Increases Ventricular Fibrillation Risk as Identified by Emulation

scientific article published on 28 August 2018

Strategies of data layout and cache writing for input-output optimization in high performance scientific computing: Applications to the forward electrocardiographic problem

scientific article published in PLoS ONE

The Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study

scientific article

The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue

scientific article published on 23 December 2011

Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase

scientific article

Variability in cardiac electrophysiology: Using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm

scientific article published on 14 December 2015

List of works by Alfonso Bueno-Orovio

Anomalous Diffusion in Cardiac Tissue as an Index of Myocardial Microstructure

Atrial Fibrillation Dynamics and Ionic Block Effects in Six Heterogeneous Human 3D Virtual Atria with Distinct Repolarization Dynamics.

Balance between sodium and calcium currents underlying chronic atrial fibrillation termination: An in silico intersubject variability study.

Basis for the Induction of Tissue-Level Phase-2 Reentry as a Repolarization Disorder in the Brugada Syndrome

Chaste: Cancer, Heart and Soft Tissue Environment

Commentary: Atrial Rotor Dynamics Under Complex Fractional Order Diffusion

ECG-based estimation of dispersion of APD restitution as a tool to stratify sotalol-induced arrhythmic risk

Electrophysiological and anatomical factors determine arrhythmic risk in acute myocardial ischaemia and its modulation by sodium current availability

Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology

Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization

High arrhythmic risk in antero-septal acute myocardial ischemia is explained by increased transmural reentry occurrence

Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity

Human ventricular activation sequence and the simulation of the electrocardiographic QRS complex and its variability in healthy and intraventricular block conditions

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop.

In Vivo and In Silico Investigation Into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes

In vivo human left-to-right ventricular differences in rate adaptation transiently increase pro-arrhythmic risk following rate acceleration

Inter-subject variability in human atrial action potential in sinus rhythm versus chronic atrial fibrillation

Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D

Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy

Minimal model for human ventricular action potentials in tissue.

Na/K pump regulation of cardiac repolarization: insights from a systems biology approach

On the Order of the Fractional Laplacian in Determining the Spatio-Temporal Evolution of a Space-Fractional Model of Cardiac Electrophysiology

Slow Recovery of Excitability Increases Ventricular Fibrillation Risk as Identified by Emulation

Strategies of data layout and cache writing for input-output optimization in high performance scientific computing: Applications to the forward electrocardiographic problem

The Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study

The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue

Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase

Variability in cardiac electrophysiology: Using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm