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List of works by Amir M. Ghaemmaghami

A Foreign Body Response-on-a-Chip Platform

scientific article published on 29 January 2019

A composite Gelatin/hyaluronic acid hydrogel as an ECM mimic for developing mesenchymal stem cell-derived epithelial tissue patches

scientific article published on 02 December 2019

A novel electrospun biphasic scaffold provides optimal three-dimensional topography for in vitro co-culture of airway epithelial and fibroblast cells.

scientific article

A paper-based in vitro model for on-chip investigation of the human respiratory system.

scientific article

Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays

scientific article

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall

scientific article

Allergen recognition by innate immune cells: critical role of dendritic and epithelial cells.

scientific article

Allergen-driven suppression of thiol production by human dendritic cells and the effect of thiols on T cell function.

scientific article published on 20 June 2008

An immunoglobulin E-reactive chimeric human immunoglobulin G1 anti-idiotype inhibits basophil degranulation through cross-linking of FcepsilonRI with FcgammaRIIb.

scientific article published on 7 December 2007

An investigation into IgE-facilitated allergen recognition and presentation by human dendritic cells

scientific article

Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte-derived dendritic cells and the dendritic cell-like KG-1 cells reveals distinct characteristics

scientific article published on January 2007

Biomimetic tissues on a chip for drug discovery.

scientific article published on 7 November 2011

Corrigendum. Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds

scientific article published on 01 April 2015

Delivery strategies to control inflammatory response: Modulating M1-M2 polarization in tissue engineering applications.

scientific article

Differential protein expression by dendritic cells from atopic and non-atopic individuals after stimulation by the major house dust mite allergen Der p 1.

scientific article

Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels

scientific article

Editorial: Adverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and Models for Biomaterial Testing

scientific article published on 11 February 2019

Effective antigen presentation to helper T cells by human eosinophils.

scientific article published on 9 August 2016

Elevated CD16 expression by monocytes from patients with tumor necrosis factor receptor-associated periodic syndrome

scientific article published in December 2007

Engineering Immunomodulatory Biomaterials To Tune the Inflammatory Response.

scientific article published on 29 April 2016

Engineering functional epithelium for regenerative medicine and in vitro organ models: a review.

scientific article published on 09 August 2013

Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation

scientific article published on 24 August 2016

Generation of anti-inflammatory macrophages for implants and regenerative medicine using self-standing release systems with a phenotype-fixing cytokine cocktail formulation

scientific article

Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins

scientific article

High seroreactivity against SARS-CoV-2 Spike epitopes in a pre SARS-CoV-2 cohort: implications for antibody testing and vaccine design

scientific article published on 22 May 2020

High-throughput approaches for screening and analysis of cell behaviors

scientific article published on 21 June 2017

Holographic optical trapping Raman micro-spectroscopy for non-invasive measurement and manipulation of live cells

scientific article published on 01 September 2018

Human T cell subset commitment determined by the intrinsic property of antigen: the proteolytic activity of the major mite allergen Der p 1 conditions T cells to produce more IL-4 and less IFN-gamma.

scientific article

Human T cells that have been conditioned by the proteolytic activity of the major dust mite allergen Der p 1 trigger enhanced immunoglobulin E synthesis by B cells

scientific article

Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds.

scientific article

Human dendritic cell sequestration onto the Necator americanus larval sheath during ex-sheathing: a possible mechanism for immune privilege.

scientific article

Image based Machine Learning for identification of macrophage subsets

scientific article

Immune Modulation by Design: Using Topography to Control Human Monocyte Attachment and Macrophage Differentiation

scientific article published on 28 April 2020

Immunocompetent 3D model of human upper airway for disease modeling and in vitro drug evaluation.

scientific article

Immunomodulation with Self-Crosslinked Polyelectrolyte Multilayer-Based Coatings.

scientific article published on 24 May 2016

Impact of surface chemistry and topography on the function of antigen presenting cells.

scientific article published on 09 January 2015

Incorporation of resident macrophages in engineered tissues: Multiple cell type response to microenvironment controlled macrophage-laden gelatine hydrogels.

scientific article

Integrin-Mediated Interactions Control Macrophage Polarization in 3D Hydrogels.

scientific article published on 7 August 2017

Investigating NF-κB signaling in lung fibroblasts in 2D and 3D culture systems.

scientific article published on December 2015

Investigating the intracellular effects of hyperbranched polycation-DNA complexes on lung cancer cells using LC-MS-based metabolite profiling

scientific article published on 01 February 2019

LC-MS metabolomics comparisons of cancer cell and macrophage responses to methotrexate and polymer-encapsulated methotrexate

scientific article published on 12 November 2019

Label-free molecular imaging of immunological synapses between dendritic and T cells by Raman micro-spectroscopy

scientific article

Laminin and fibronectin treatment leads to generation of dendritic cells with superior endocytic capacity

scientific article

Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release

scientific article

Microfluidics for Advanced Drug Delivery Systems

scientific article published on 04 February 2015

Nanofibrous Scaffolds Support a 3D Permeability Model of the Human Intestinal Epithelium

scientific article published on 10 May 2019

New generation of bioreactors that advance extracellular matrix modelling and tissue engineering

scientific article

Nuclear trafficking, histone cleavage and induction of apoptosis by the meningococcal App and MspA autotransporters.

scientific article published on 08 February 2015

Photocrosslinkable Gelatin Hydrogel for Epidermal Tissue Engineering

scientific article

Photocrosslinkable Gelatin Hydrogels Modulate the Production of the Major Pro-inflammatory Cytokine, TNF-α, by Human Mononuclear Cells

scholarly article by Amy R Donaldson et al published 2018 in Frontiers in Bioengineering and Biotechnology

Post-processing of polymer foam tissue scaffolds with high power ultrasound: a route to increased pore interconnectivity, pore size and fluid transport.

scientific article published on 7 August 2013

Recognition of the major cat allergen Fel d 1 through the cysteine-rich domain of the mannose receptor determines its allergenicity

scientific article

Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite

scientific article published on 28 December 2011

Role of Rho-Associated Coiled-Coil Forming Kinase Isoforms in Regulation of Stiffness-Induced Myofibroblast Differentiation in Lung Fibrosis

scientific article published on 22 February 2017

Self-reporting scaffolds for 3-dimensional cell culture

scientific article

Single-Cell Metabolic Profiling of Macrophages Using 3D OrbiSIMS: Correlations with Phenotype

scientific article published in 2022

Superior T cell activation by ESAT-6 as compared with the ESAT-6-CFP-10 complex.

scientific article published on 26 September 2005

Surgical Materials: Current Challenges and Nano-enabled Solutions.

scientific article

TLR2 stimulation regulates the balance between regulatory T cell and Th17 function: a novel mechanism of reduced regulatory T cell function in multiple sclerosis.

scientific article published on 15 May 2015

The Cross-Talk between miR-511-3p and C-Type Lectin Receptors on Dendritic Cells Affects Dendritic Cell Function

scientific article published on 22 May 2019

The complement receptor 3, CR3 (CD11b/CD18), on T lymphocytes: activation-dependent up-regulation and regulatory function

scientific article (publication date: April 2001)

The detection of ADAM8 protein on cells of the human immune system and the demonstration of its expression on peripheral blood B cells, dendritic cells and monocyte subsets

scientific article published on 18 September 2006

The development of a 3D immunocompetent model of human skin

scientific article published on 23 July 2013

The glycosylation pattern of common allergens: the recognition and uptake of Der p 1 by epithelial and dendritic cells is carbohydrate dependent

scientific article

The impact of surface chemistry modification on macrophage polarisation

scientific article published on 14 June 2016

The mannose receptor mediates the uptake of diverse native allergens by dendritic cells and determines allergen-induced T cell polarization through modulation of IDO activity

scientific article published on 7 July 2010

The mannose receptor negatively modulates the Toll-like receptor 4-aryl hydrocarbon receptor-indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization

scientific article

The molecular basis of allergenicity.

scientific article published on 24 October 2008

The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: experimental analysis of in silico substrate identification and implications in allergic responses

scientific article published in February 2007

The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: allergen-induced Th2 bias determined at the dendritic cell level

scientific article published in October 2002

The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs.

scientific article published on 03 March 2017

The role of lectins in allergic sensitization and allergic disease

scientific article published on 25 March 2013

Tissue transglutaminase (TG-2) modified amniotic membrane: a novel scaffold for biomedical applications

scientific article published on 01 June 2012

Tissue transglutaminase treatment leads to concentration-dependent changes in dendritic cell phenotype--implications for the role of transglutaminase in coeliac disease.

scientific article

Unbiased Analysis of the Impact of Micropatterned Biomaterials on Macrophage Behavior Provides Insights beyond Predefined Polarization States

Uniform cell colonization of porous 3-D scaffolds achieved using radial control of surface chemistry

scientific article