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List of works by Mitch Dowsett

10th International Aromatase Conference Proceedings, September 2010. Preface

scientific article published on 23 March 2011

11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial

scientific article published on 16 February 2017

2 years versus 1 year of adjuvant trastuzumab for HER2-positive breast cancer (HERA): an open-label, randomised controlled trial

scientific article published on 18 July 2013

2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial

scientific article published in January 2007

20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

scientific article published on November 2017

A dual-center randomized controlled double blind trial assessing the effect of acupuncture in reducing musculoskeletal symptoms in breast cancer patients taking aromatase inhibitors ⬇️

scientific article published on February 8, 2013

A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance

scientific article published on 23 February 2011

A luminal breast cancer genome atlas: progress and barriers

scientific article

A marker of homologous recombination predicts pathologic complete response to neoadjuvant chemotherapy in primary breast cancer

scientific article published on 27 August 2010

A poetic story: lessons learnt from the world's largest breast cancer window of opportunity study.

scientific article published on 16 November 2015

Abstract P3-06-01: Nuclear β-catenin negativity predicts for late relapse in ER+, tamoxifen-treated breast cancer

Abstract S1-04: Exome sequencing of post-menopausal ER+ breast cancer (BC) treated pre-surgically with aromatase inhibitors (AIs) in the POETIC trial (CRUK/07/015)

Abstract S3-01: The TNT trial: A randomized phase III trial of carboplatin (C) compared with docetaxel (D) for patients with metastatic or recurrent locally advanced triple negative or BRCA1/2 breast cancer (CRUK/07/012)

scientific article published on 30 April 2015

Accurate Prediction and Validation of Response to Endocrine Therapy in Breast Cancer

scientific article

Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines

scientific article published on 01 June 2006

Adjuvant use of anastrozole in breast cancer

scientific article published in April 2004

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer

scientific article published in June 2010

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version).

scientific article published on July 2010

An international Ki67 reproducibility study

scientific article

An international study to increase concordance in Ki67 scoring

scientific article published on 20 February 2015

Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer.

scientific article

Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration

scientific article

Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial

scientific article published on 12 December 2013

Aromatase and its inhibitors: significance for breast cancer therapy

scientific article

Aromatase inhibitors for breast cancer: lessons from the laboratory

scientific article published on November 2003

Aromatase inhibitors in breast cancer

scientific article

Aromatase inhibitors: combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance

scientific article

Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group ⬇️

scientific article published on September 29, 2011

Assessment of the Spatial Heterogeneity of Breast Cancers: Associations Between Computed Tomography and Immunohistochemistry.

scientific article published on 4 June 2019

Association between breast cancer subtypes and response to neoadjuvant anastrozole

scientific article published on 5 April 2011

Association between endogenous plasma hormone concentrations and fracture risk in men and women: the EPIC-Oxford prospective cohort study

scientific article

Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men

article

Author Correction: The prognostic effects of somatic mutations in ER-positive breast cancer

scientific article published in Nature Communications

BCL-2: a new therapeutic target in estrogen receptor-positive breast cancer?

scientific article published in July 2013

BRCA1/BRCA2 mutation status and analysis of cancer family history in participants of the Royal Marsden Hospital tamoxifen chemoprevention trial

article

Biological characteristics of the pure antiestrogen fulvestrant: overcoming endocrine resistance

scientific article

Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer

scientific article published on 09 February 2017

Biomarker changes during neoadjuvant anastrozole, tamoxifen, or the combination: influence of hormonal status and HER-2 in breast cancer--a study from the IMPACT trialists

scientific article

Biomarker investigations from the ATAC trial: the role of TA01.

scientific article published in January 2004

Biomarkers for the clinical management of breast cancer: International perspective ⬇️

scientific article published on February 8, 2013

Birthweight and body size throughout life in relation to sex hormones and prolactin concentrations in premenopausal women

scientific article published in December 2006

Breast cancer biomarkers in clinical testing: analysis of a UK national external quality assessment scheme for immunocytochemistry and in situ hybridisation database containing results from 199 300 patients

article published in 2018

Breast cancer molecular profiling with single sample predictors: a retrospective analysis

scientific article

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article

Breast cancer: aromatase inhibitors take on tamoxifen

scientific article published in December 2002

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer

scientific article

CYP2D6 Genotype Should Not Be Used for Deciding About Tamoxifen Therapy in Postmenopausal Breast Cancer ⬇️

scientific article published on June 17, 2013

CYP2D6 and UGT2B7 genotype and risk of recurrence in tamoxifen-treated breast cancer patients

scientific article published on 6 March 2012

CYP3A variation, premenopausal estrone levels, and breast cancer risk

scientific article published on 3 April 2012

Cell filtration‐laser scanning cytometry for the characterisation of circulating breast cancer cells ⬇️

scientific article published on October 1, 2003

Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease.

scientific article

Changes in bone mineral density at 3 years in postmenopausal women receiving anastrozole and risedronate in the IBIS-II bone substudy: an international, double-blind, randomised, placebo-controlled trial

scientific article published on 11 November 2014

Changes in estradiol and testosterone levels in postmenopausal women after changes in body mass index

scientific article published on 10 May 2013

Childhood body size and pubertal timing in relation to adult mammographic density phenotype

scientific article published on 07 February 2017

Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer

scientific article

Cigarette Smoking and Endogenous Sex Hormones in Postmenopausal Women

article

Circulating tumour cells in breast cancer

scientific article published on February 2004

Clinical and Biochemical Consequences of CYP17A1 Inhibition with Abiraterone Given with and without Exogenous Glucocorticoids in Castrate Men with Advanced Prostate Cancer

scholarly article by Gerhardt Attard et al published February 2012 in The Journal of Clinical Endocrinology and Metabolism

Clinical strategies for rationale combinations of aromatase inhibitors with novel therapies for breast cancer

scientific article published on 24 May 2007

Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer.

scientific article

Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole in Postmenopausal Patients With Hormone Receptor-Positive, Node-Positive Early Breast Cancer: Final Results of the Randomized Phase III Femara Versus Anastrozole Clinical Evalu

scientific article published on 23 January 2017

Comparison of EndoPredict and EPclin With Oncotype DX Recurrence Score for Prediction of Risk of Distant Recurrence After Endocrine Therapy.

scientific article published on 10 July 2016

Comparison of methods to measure low serum estradiol levels in postmenopausal women

scientific article published in August 2006

Comparison of protein expression between formalin-fixed core-cut biopsies and surgical excision specimens using a novel multiplex approach.

scientific article published on 22 February 2019

Comparison of the Performance of 6 Prognostic Signatures for Estrogen Receptor-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial

scientific article published on 15 February 2018

Comparison of the selective estrogen receptor modulator arzoxifene (LY353381) with tamoxifen on tumor growth and biomarker expression in an MCF-7 human breast cancer xenograft model ⬇️

scientific article published on October 1, 2003

Correlation between cyclooxygenase-2 expression and angiogenesis in human breast cancer.

scientific article

Correlation of Age and HRT Use with Breast Density as Assessed by Quantra™ ⬇️

scientific article published on December 10, 2012

Critical assessment of new risk factors for breast cancer: considerations for development of an improved risk prediction model

scientific article

Cross Stratification and Differential Risk by Breast Cancer Index and Recurrence Score in women with hormone receptor positive lymph-node negative early stage breast cancer

scientific article published in June 2016

Current and emerging biomarkers in breast cancer: prognosis and prediction

scientific article published on 23 September 2010

Current perspectives on HER2 testing: a review of national testing guidelines

scientific article

Current status of HER2 testing

scientific article

Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis

scientific article

Deficits in plasma oestradiol measurement in studies and management of breast cancer

scientific article

Designing the future shape of breast cancer diagnosis, prognosis and treatment

scientific article published on January 2004

Differences in expression of proliferation-associated genes and RANKL across the menstrual cycle in estrogen receptor-positive primary breast cancer

scientific article

Digital mammographic density and breast cancer risk: a case-control study of six alternative density assessment methods

scientific article

Discordance between oncotype DX recurrence score and RSPC for predicting residual risk of recurrence in ER-positive breast cancer

scientific article

Disease-free survival according to degree of HER2 amplification for patients treated with adjuvant chemotherapy with or without 1 year of trastuzumab: the HERA Trial

scientific article published on 13 April 2009

ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer ⬇️

scientific article

ERBB2 influences the subcellular localization of the estrogen receptor in tamoxifen-resistant MCF-7 cells leading to the activation of AKT and RPS6KA2.

scientific article published on 29 September 2008

ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer

scientific article

Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor-Positive Breast Cancer

scientific article

Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial

scientific article published on 17 November 2010

Effect of body mass index on recurrences in tamoxifen and anastrozole treated women: an exploratory analysis from the ATAC trial

scientific article published on 14 June 2010

Effect of tibolone on breast cancer cell proliferation in postmenopausal ER+ patients: results from STEM trial

scientific article

Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo ⬇️

scientific article published on October 17, 2012

Effects of Estrogen Receptor and Human Epidermal Growth Factor Receptor-2 Levels on the Efficacy of Trastuzumab: A Secondary Analysis of the HERA Trial

scientific article published on 21 April 2016

Effects of Vaginal Estrogens on Serum Estradiol Levels in Postmenopausal Breast Cancer Survivors and Women at Risk of Breast Cancer Taking an Aromatase Inhibitor or a Selective Estrogen Receptor Modulator ⬇️

scientific article published on February 7, 2012

Effects of cyclin D1 gene amplification and protein expression on time to recurrence in postmenopausal breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study

scientific article

Effects of the aromatase inhibitor letrozole on normal breast epithelial cell proliferation and metabolic indices in postmenopausal women: a pilot study for breast cancer prevention.

scientific article published in July 2002

Efforts to link biological and clinical breast cancer research

scientific article published in December 2003

Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation

scientific article published on July 2005

Emerging biomarkers and new understanding of traditional markers in personalized therapy for breast cancer

scientific article published on December 2008

Emerging technologies for assessing HER2 amplification

scientific article

Endocrine effects of aromatase inhibitors

scientific article published on 19 January 2010

Endocrinology and hormone therapy in breast cancer: aromatase inhibitors versus antioestrogens

scientific article

Endogenous sex hormones, breast cancer risk, and tamoxifen response: an ancillary study in the NSABP Breast Cancer Prevention Trial (P-1).

scientific article published in January 2006

Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women

scientific article published on 01 October 2006

Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study

scientific article published on 26 November 2007

Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation

scientific article published on 29 May 2003

Enhancing endocrine response with novel targeted therapies: why have the clinical trials to date failed to deliver on the preclinical promise?

scientific article published on February 2008

Estrogen receptor: a never ending story?

scientific article published on 27 June 2011

Evaluation of Ki-67 proliferation and apoptotic index before, during and after neoadjuvant chemotherapy for primary breast cancer

scientific article

Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation

scientific article published in January 2007

Exploring breast cancer estrogen disposition: the basis for endocrine manipulation

scientific article published on 26 July 2011

Expression of key oestrogen-regulated genes differs substantially across the menstrual cycle in oestrogen receptor-positive primary breast cancer ⬇️

scientific article published on February 3, 2013

Extreme loss of immunoreactive p-Akt and p-Erk1/2 during routine fixation of primary breast cancer ⬇️

scientific article published on September 28, 2010

Factors predicting late recurrence for estrogen receptor-positive breast cancer

scientific article published on 12 September 2013

Familial correlations in postmenopausal serum concentrations of sex steroid hormones and other mitogens: a twins and sisters study

scientific article published on 22 October 2009

Feasibility of using tissue microarray cores of paraffin-embedded breast cancer tissue for measurement of gene expression: a proof-of-concept study

scientific article published in June 2010

Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, mult

scientific article published on 29 July 2013

GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors

scientific article published on 06 May 2013

Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study

scientific article published on 13 October 2017

Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (cytoxan) (AC) response and resistance

scientific article published in February 2006

Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer

scientific article

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

scientific article

Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women

scientific article

Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines

scientific article

HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity ⬇️

scientific article published on June 28, 2013

HER2 testing in the UK: consensus from a national consultation

scientific article

Heterogeneity in global gene expression profiles between biopsy specimens taken peri-surgically from primary ER-positive breast carcinomas

scientific article published on April 2016

High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

scientific article published on 06 April 2016

Human epidermal growth factor receptor 2 status correlates with lymph node involvement in patients with estrogen receptor (ER) negative, but with grade in those with ER-positive early-stage breast cancer suitable for cytotoxic chemotherapy

scientific article published in October 2007

Human epidermal growth factor receptor-2 and hormonal therapies: clinical implications.

scientific article

Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women

scientific article

Immunohistochemical Phenotype of Breast Cancer during 25-Year Follow-up of the Royal Marsden Tamoxifen Prevention Trial

scientific article published on 18 January 2017

Impact of a Panel of 88 Single Nucleotide Polymorphisms on the Risk of Breast Cancer in High-Risk Women: Results From Two Randomized Tamoxifen Prevention Trials

scientific article published on 28 December 2016

Impact of aromatase inhibitor treatment on global gene expression and its association with antiproliferative response in ER+ breast cancer in postmenopausal patients

scientific article published on 31 December 2019

Impact of estrogen deprivation on gene expression profiles of normal postmenopausal breast tissue in vivo

scientific article published in April 2008

Impact of mutational profiles on response of primary oestrogen receptor-positive breast cancers to oestrogen deprivation

scientific article

Impact of type of full-field digital image on mammographic density assessment and breast cancer risk estimation: a case-control study

scientific article published on 26 September 2016

Implications of Gene-Environment Interaction in Studies of Gene Variants in Breast Cancer: An Example of Dietary Isoflavones and the D356N Polymorphism in theSex Hormone-Binding GlobulinGene: Figure 1

article

In Reply

Incomplete Estrogen Suppression With Gonadotropin-Releasing Hormone Agonists May Reduce Clinical Efficacy in Premenopausal Women With Early Breast Cancer

scientific article published on 04 January 2016

Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study

scientific article published in February 2002

Influence of sex hormones on cancer progression

scientific article published on 19 July 2010

Influences on circulating oestrogens in postmenopausal women: relationship with breast cancer

scientific article published on 7 November 2006

Integration of Clinical Variables for the Prediction of Late Distant Recurrence in Patients With Estrogen Receptor-Positive Breast Cancer Treated With 5 Years of Endocrine Therapy: CTS5

Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer

scientific article

Integrative analyses identify modulators of response to neoadjuvant aromatase inhibitors in patients with early breast cancer

scientific article published on 11 March 2015

International Web-based consultation on priorities for translational breast cancer research

scientific article

International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010).

scientific article published on January 2011

Interpreting plasma estrogen levels in breast cancer: caution needed

scientific article published on 14 April 2014

Intratumoral estrogen disposition in breast cancer

scientific article published on 9 March 2010

Intrinsic Subgroups or Individual Biomarkers for Predicting Outcome of Metastatic Breast Cancer?

scientific article published on 9 June 2016

Introduction to sessions on 'Predicting personal risk for breast cancer'

scientific article published on 18 December 2008

Introduction to sessions on Personalising treatment

scientific article

Lapatinib restores hormone sensitivity with differential effects on estrogen receptor signaling in cell models of human epidermal growth factor receptor 2-negative breast cancer with acquired endocrine resistance

scientific article

Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer

scientific article published in April 2008

Life following aromatase inhibitors--where now for endocrine sequencing?

scientific article

Measurement of proliferation marker Ki67 in breast tumour FNAs using laser scanning cytometry in comparison to conventional immunocytochemistry ⬇️

scientific article published on November 1, 2003

Mechanisms of disease: angiogenesis and the management of breast cancer

scientific article published on September 2007

Mechanisms of resistance to aromatase inhibitors

scientific article

Mechanisms of tamoxifen resistance

scientific article

Menstrual cycle associated changes in hormone-related gene expression in oestrogen receptor positive breast cancer

scientific article published on 15 November 2019

Menstrual cycle characteristics and steroid hormone, prolactin, and growth factor levels in premenopausal women

scientific article

Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen

scientific article published on 30 November 2009

Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement

scientific article

Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis

scientific article

Molecular Drivers of Oncotype DX, Prosigna, EndoPredict, and the Breast Cancer Index: A TransATAC Study

scientific article published on 27 October 2020

Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation

scientific article

Molecular changes in premenopausal oestrogen receptor-positive primary breast cancer in Vietnamese women after oophorectomy

scientific article published on 27 November 2017

Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase

scientific article

Molecular response to aromatase inhibitor treatment in primary breast cancer

scientific article published in January 2007

Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer

scientific article published in August 2015

Neoadjuvant endocrine therapy: Patient selection, treatment duration and surrogate endpoints

scientific article published on 06 August 2015

Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: the Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial

scientific article published on 5 July 2005

New and translational perspectives of oestrogen deprivation in breast cancer

scientific article published on 19 January 2011

New biology of the oestrogen receptor

scientific article published on 01 July 2003

Non-existence of caveolin-1 gene mutations in human breast cancer

scientific article published on 11 September 2011

Novel concepts for the chemoprevention of breast cancer through aromatase inhibition

scientific article published on September 2006

Optimizing the implementation of future treatment using surrogate end-points

scientific article published on 18 December 2008

Origin and characteristics of adverse events in aromatase inhibition therapy for breast cancer ⬇️

scientific article published on August 1, 2003

Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics

scientific article published on 23 September 2008

Ovarian protection with goserelin during adjuvant chemotherapy for pre-menopausal women with early breast cancer (EBC).

scientific article published on 13 September 2007

Paracrine-stimulated gene expression profile favors estradiol production in breast tumors

scientific article published on 2 June 2006

Past oral contraceptive and hormone therapy use and endogenous hormone concentrations in postmenopausal women

article

Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer

scientific article

Phosphorylation of AKT pathway proteins is not predictive of benefit of taxane therapy in early breast cancer

scientific article published on 28 March 2013

Physical activity and inactivity in relation to sex hormone, prolactin, and insulin-like growth factor concentrations in premenopausal women - exercise and premenopausal hormones

scientific article published on 05 June 2007

Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-norfolk.

scientific article

Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions.

scientific article published in January 2005

Plasma ESR1 Mutations and the Treatment of Estrogen Receptor-Positive Advanced Breast Cancer.

scientific article published on 06 June 2016

Polymorphisms associated with circulating sex hormone levels in postmenopausal women

scientific article

Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men

article

Polymorphisms of CYP19A1 and response to aromatase inhibitors in metastatic breast cancer patients

scientific article published on 15 March 2012

Pre-surgical study of the biological effects of the selective cyclo-oxygenase-2 inhibitor celecoxib in patients with primary breast cancer

scientific article published on 10 August 2010

Predicting response to cytotoxic drugs – the endocrine part of the story ⬇️

scientific article published on October 1, 2011

Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: a TransATAC study

scientific article published on 8 March 2010

Predictive algorithms for adjuvant therapy: TransATAC.

scientific article published on 4 April 2011

Predictive and prognostic factors ⬇️

scientific article published on December 20, 2010

Preoperative models to evaluate endocrine strategies for breast cancer

scientific article

Proceedings of the Fifth International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer: conference summary statement

scientific article published in February 2006

Progesterone receptor A predominance is a discriminator of benefit from endocrine therapy in the ATAC trial

scientific article published on 28 April 2015

Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer

scientific article published on 11 October 2011

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

scientific article published on 18 October 2016

Proliferation and apoptosis as markers of benefit in neoadjuvant endocrine therapy of breast cancer

scientific article published in February 2006

Proliferation marker Ki-67 in early breast cancer

scientific article

RAZOR: A Phase II Open Randomized Trial of Screening Plus Goserelin and Raloxifene Versus Screening Alone in Premenopausal Women at Increased Risk of Breast Cancer

scientific article

Recent data on intratumor estrogens in breast cancer

scientific article

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update

scientific article

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update

article

Red-clover-derived isoflavones and mammographic breast density: a double-blind, randomized, placebo-controlled trial [ISRCTN42940165]

scientific article

Reduced progesterone levels explain the reduced risk of breast cancer in obese premenopausal women: a new hypothesis

scientific article

Reduction in angiogenesis after neoadjuvant chemoendocrine therapy in patients with operable breast carcinoma

scientific article published on 01 May 1999

Relationship between plasma estradiol levels and estrogen-responsive gene expression in estrogen receptor-positive breast cancer in postmenopausal women

scientific article

Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (HER-2) status with recurrence in the Arimidex, Tamoxifen, Alone or in Combination trial

scientific article published on 28 January 2008

Relationship of PIK3CA mutation and pathway activity with antiproliferative response to aromatase inhibition

scientific article

Relationship of ZNF423 and CTSO with breast cancer risk in two randomised tamoxifen prevention trials.

scientific article published on 11 July 2016

Relationship of body mass index with aromatisation and plasma and tissue oestrogen levels in postmenopausal breast cancer patients treated with aromatase inhibitors

scientific article published on 4 February 2014

Reply to E.A. Rakha et al.

scientific article

Reply to R. Bhargava et al and K. Lambein et al.

scientific article

Retrospective analysis of molecular scores for the prediction of distant recurrence according to baseline risk factors.

scientific article published on 22 July 2016

Retrospective analysis of time to recurrence in the ATAC trial according to hormone receptor status: an hypothesis-generating study

scientific article published in October 2005

Revisiting the technical validation of tumour biomarker assays: how to open a Pandora's box ⬇️

scientific article published on April 19, 2011

Risk of Recurrence and Chemotherapy Benefit for Patients With Node-Negative, Estrogen Receptor–Positive Breast Cancer: Recurrence Score Alone and Integrated With Pathologic and Clinical Factors ⬇️

scientific article published on October 17, 2011

Risk of recurrence estimates with IHC4+C are tolerant of variations in staining and scoring: an analytical validity study

scientific article published on 17 August 2015

Role of biologic markers in patient selection and application to disease prevention

scientific article published in August 2003

Second International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: summary consensus statement.

scientific article

Selection of REFERENCE genes for normalization of qRT-PCR data derived from FFPE breast tumors

scientific article

Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer

scientific article published on 26 May 2009

Selective oestrogen receptor modulators in prevention of breast cancer: an updated meta-analysis of individual participant data

scientific article

Sex hormones and breast cancer risk and prognosis

scientific article published on August 2013

Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women

scientific article published on 22 June 2009

Short-term changes in Ki-67 during neoadjuvant treatment of primary breast cancer with anastrozole or tamoxifen alone or combined correlate with recurrence-free survival

scientific article published in January 2005

Short-term presurgical treatment for all?

scientific article

Src Is a Potential Therapeutic Target in Endocrine-Resistant Breast Cancer Exhibiting Low Estrogen Receptor-Mediated Transactivation

scientific article

Standardization of HER2 testing: results of an international proficiency-testing ring study

scientific article published on 30 March 2007

Synergistic activity of letrozole and sorafenib on breast cancer cells

scientific article

Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis

scientific article

Testosterone, SHBG and differential white blood cell count in middle-aged and older men.

scientific article published on 4 January 2012

The association of plasma DHEA and DHEA sulfate with breast cancer risk in predominantly premenopausal women

scientific article published in May 2006

The biology of steroid hormones and endocrine treatment of breast cancer

scientific article

The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis

scientific article

The effects of neoadjuvant anastrozole and tamoxifen on circulating vascular endothelial growth factor and soluble vascular endothelial growth factor receptor 1 in breast cancer

scientific article published in May 2008

The effects of phytoestrogen isoflavones on bone density in women: a double-blind, randomized, placebo-controlled trial

scientific article published in February 2004

The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo

scientific article

The feasibility of using fine needle aspiration from primary breast cancers for cDNA microarray analyses

scientific article published on March 2002

The potential of new technologies/approaches. Introduction to Sessions 3 and 4.

scientific article published on 18 December 2009

The prognostic effects of somatic mutations in ER-positive breast cancer

scientific article published in Nature Communications

The relationship between factors affecting endogenous oestradiol levels in postmenopausal women and breast cancer

scientific article published on 17 October 2006

The role of caveolin-1 in human breast cancer ⬇️

scientific article published on 08 September 2011

The vascular endothelial growth factor receptor inhibitor PTK787/ZK222584 inhibits aromatase

scientific article published on 12 May 2009

Total body aromatization in postmenopausal breast cancer patients is strongly correlated to plasma leptin levels

scientific article

Transient over-expression of estrogen receptor-α in breast cancer cells promotes cell survival and estrogen-independent growth

scientific article published on 22 August 2010

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

scientific article

Trastuzumab-associated cardiac events at 8 years of median follow-up in the Herceptin Adjuvant trial (BIG 1-01).

scientific article

Treatment with high-dose estrogen (diethylstilbestrol) significantly decreases plasma estrogen and androgen levels but does not influence in vivo aromatization in postmenopausal breast cancer patients

scientific article published in September 2005

Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients

scientific article

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

scientific article published on 19 April 2020

Urinary 6-sulfatoxymelatonin levels and their correlations with lifestyle factors and steroid hormone levels

scientific article published in March 2006

Value and limitations of measuring HER-2 extracellular domain in the serum of breast cancer patients

scientific article published on 02 March 2009

Weight change associated with anastrozole and tamoxifen treatment in postmenopausal women with or at high risk of developing breast cancer

scientific article published on 16 May 2012

Who would have thought a single Ki67 measurement would predict long-term outcome?

scientific article

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