List of works - Loreto Gesualdo

A European multicentre and open-label controlled randomized trial to evaluate the efficacy of Sequential treatment with TAcrolimus-Rituximab versus steroids plus cyclophosphamide in patients with primary MEmbranous Nephropathy: the STARMEN study

scientific article

A new model of acute care hospitals and the role of nephrologists

scientific article published on 01 January 2012

A novel SMARCAL1 mutation associated with a mild phenotype of Schimke immuno-osseous dysplasia (SIOD).

scientific article

A pharmacoepidemiological study of the multi-level determinants, predictors, and clinical outcomes of biosimilar epoetin alfa for renal anaemia in haemodialysis patients: background and methodology of the MONITOR-CKD5 study.

scientific article

A type I interferon signature characterizes chronic antibody-mediated rejection in kidney transplantation

scientific article published on 04 June 2015

Acquired lecithin:cholesterol acyltransferase deficiency as a major factor in lowering plasma HDL levels in chronic kidney disease

scientific article published on 01 August 2014

Albuminuria as a risk factor for mild cognitive impairment and dementia—what is the evidence?

scientific article published on 5 November 2021

Allograft nephrectomy: what is the best surgical technique?

scientific article published on 01 September 2012

Altered urinary excretion of aquaporin 2 in IgA nephropathy

scientific article published on 08 August 2011

Arteriovenous fistula stenosis in hemodialysis patients is characterized by an increased adventitial fibrosis

scientific article published on 27 February 2014

Author Correction: The copy number variation landscape of congenital anomalies of the kidney and urinary tract

scientific article published on 01 April 2019

CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS).

scientific article

Clinical features and long-term outcome of nephrotic syndrome associated with heterozygous NPHS1 and NPHS2 mutations

scientific article published on 30 April 2009

Coagulation activation is associated with nicotinamide adenine dinucleotide phosphate oxidase-dependent reactive oxygen species generation in hemodialysis patients

scientific article published on 22 December 2011

Coexistence of different circulating anti-podocyte antibodies in membranous nephropathy.

scientific article

Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pERK Signaling.

scientific article published on 23 May 2018

Complement Modulation of Anti-Aging Factor Klotho in Ischemia/Reperfusion Injury and Delayed Graft Function

scientific article published on 17 August 2015

Complement-dependent NADPH oxidase enzyme activation in renal ischemia/reperfusion injury

scientific article published on 10 July 2014

Copy-number disorders are a common cause of congenital kidney malformations

scientific article

De novo homozygous mutation of the C1 inhibitor gene in a patient with hereditary angioedema

scientific article published on 17 May 2013

Defective gene expression of the membrane complement inhibitor CD46 in patients with progressive immunoglobulin A nephropathy.

scientific article published on 9 April 2018

Dexamethasone modulates interleukin-12 production by inducing monocyte chemoattractant protein-1 in human dendritic cells.

scientific article published on 14 August 2007

Diagnostic and prognostic role of preoperative circulating CA 15-3, CA 125, and beta-2 microglobulin in renal cell carcinoma.

scientific article published on 17 February 2014

Dialysis-related systemic microinflammation is associated with specific genomic patterns.

scientific article published on 29 November 2007

Dialysis-related transcriptomic profiling: the pivotal role of heparanase

scientific article

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens

scientific article

Downregulation of nuclear-encoded genes of oxidative metabolism in dialyzed chronic kidney disease patients

scientific article (publication date: 2013)

ERA-EDTA Immunonephrology working group

Early withdrawal of cyclosporine A improves 1-year kidney graft structure and function in sirolimus-treated patients.

scientific article published in April 2003

Effect of Whole-Grain Barley on the Human Fecal Microbiota and Metabolome

scientific article published on 18 September 2015

Effect of an l-Carnitine–Containing Peritoneal Dialysate on Insulin Sensitivity in Patients Treated With CAPD: A 4-Month, Prospective, Multicenter Randomized Trial

scientific article published on 29 May 2013

Emerging biomarkers in renal damage

scientific article published on 3 September 2014

Endothelial dysfunction and renal fibrosis in endotoxemia-induced oliguric kidney injury: possible role of LPS-binding protein.

scientific article

Endothelial-to-mesenchymal transition and renal fibrosis in ischaemia/reperfusion injury are mediated by complement anaphylatoxins and Akt pathway

scientific article published on 23 January 2014

Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome

article

Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations

scientific article published in November 2017

Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations

scientific article published in December 2017

Exposure to low- vs iso-osmolar contrast agents reduces NADPH-dependent reactive oxygen species generation in a cellular model of renal injury.

scientific article published in December 2013

Fecal Microbiota Transplantation in Reducing Uremic Toxins Accumulation in Kidney Disease: Current Understanding and Future Perspectives

scientific article published in 2023

Focus on renal blood flow in mechanically ventilated patients with SARS-CoV-2: a prospective pilot study

scientific article published on 01 January 2021

Genetic Drivers of Kidney Defects in the DiGeorge Syndrome

scientific article

Genome-wide analysis of differentially expressed genes and splicing isoforms in clear cell renal cell carcinoma

scientific article

Hepatitis C virus-related proteins in kidney tissue from hepatitis C virus-infected patients with cryoglobulinemic membranoproliferative glomerulonephritis.

scientific article published on May 1997

High dickkopf-1 levels in sera and leukocytes from children with 21-hydroxylase deficiency on chronic glucocorticoid treatment.

scientific article

ID2-VEGF-related pathways in the pathogenesis of Kaposi's sarcoma: a link disrupted by rapamycin.

scientific article

Impact of transplant nephrectomy on retransplantation: a single-center retrospective study.

scientific article published on 15 November 2012

Increasing relevance of donor-specific antibodies in antibody-mediated rejection.

scientific article published on 20 December 2012

Independent role of high central venous pressure in predicting worsening of renal function in chronic heart failure outpatients.

scientific article

Ischemia-reperfusion injury-induced abnormal dendritic cell traffic in the transplanted kidney with delayed graft function

scientific article published on 08 August 2007

JAK3/STAT5/6 pathway alterations are associated with immune deviation in CD8 T cells in renal cell carcinoma patients.

scientific article

Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients.

scientific article

LPS removal reduces CD80-mediated albuminuria in critically ill patients with Gram-negative sepsis

scientific article published on 23 January 2019

LPS-Binding Protein Modulates Acute Renal Fibrosis by Inducing Pericyte-to-Myofibroblast Trans-Differentiation through TLR-4 Signaling

scientific article published on 27 July 2019

Local synthesis of interferon-alpha in lupus nephritis is associated with type I interferons signature and LMP7 induction in renal tubular epithelial cells.

scientific article

Mechanisms of enhanced osteoclastogenesis in girls and young women with Turner's Syndrome

scientific article published on 21 July 2015

Microbiota and metabolome associated with immunoglobulin A nephropathy (IgAN).

scientific article

Mutational Spectrum of CYP24A1 Gene in a Cohort of Italian Patients with Idiopathic Infantile Hypercalcemia.

scientific article

Mutations in DSTYK and dominant urinary tract malformations

scientific article

NLRP3 inflammasome activation in dialyzed chronic kidney disease patients

scientific article

Neuropeptide Y as a risk factor for cardiorenal disease and cognitive dysfunction in chronic kidney disease: translational opportunities and challenges

scientific article published on 9 December 2021

Nocturnal haemodialysis is associated with a reduced occurrence of low triiodothyronine serum levels in haemodialysed patients

scientific article published on 10 February 2020

Novel INF2 mutations in an Italian cohort of patients with focal segmental glomerulosclerosis, renal failure and Charcot-Marie-Tooth neuropathy

article

Occipital sources of resting-state alpha rhythms are related to local gray matter density in subjects with amnesic mild cognitive impairment and Alzheimer's disease

scientific article

Occult HBV infection in hemodialysis setting is marked by presence of isolated antibodies to HBcAg and HCV.

scientific article

Osteoclastogenic potential of peripheral blood mononuclear cells in cleidocranial dysplasia

scientific article published on 20 February 2014

Paraneoplastic focal segmental glomerulosclerosis in sarcomatoid renal cell cancer.

scientific article published on 24 March 2014

Percutaneous ultrasound-guided renal biopsy in supine antero-lateral position: a new approach for obese and non-obese patients

scientific article published on 31 October 2007

Posttransplant Recurrence of Proteinuria in a Case of Focal Segmental Glomerulosclerosis Associated with WT1 Mutation

scientific article published on 19 June 2006

Pre-existing type 2 diabetes mellitus is an independent risk factor for mortality and progression in patients with renal cell carcinoma.

scientific article

Preservation of renal function in atypical hemolytic uremic syndrome by eculizumab: a case report

scientific article

Prevalence and cardiovascular risk profile of chronic kidney disease in Italy: results of the 2008-12 National Health Examination Survey

scientific article published on 18 December 2014

Proteinuria: from molecular to clinical applications in glomerulonephritis.

scientific article published on 22 August 2012

Purification and identification of peptides with high angiotensin-I converting enzyme (ACE) inhibitory activity from honeybee pupae (Apis mellifera) hydrolysates with in silico gastrointestinal digestion

scientific article published in 2019

Rapamycin for treatment of type I autosomal dominant polycystic kidney disease (RAPYD-study): a randomized, controlled study

scientific article published on 10 July 2012

Rapamycin induces ILT3(high)ILT4(high) dendritic cells promoting a new immunoregulatory pathway

scientific article published on 09 October 2013

Renal angiomyolipomatosis and Kaposi's sarcoma: a possible link disrupted by sirolimus.

scientific article published in August 2012

Renal lesions in patients with type 2 diabetes: a puzzle waiting to be solved

scientific article

Risk-based individualisation of target haemoglobin in haemodialysis patients with renal anaemia in the post-TREAT era: theoretical attitudes versus actual practice patterns (MONITOR-CKD5 study).

scientific article

Serum fetuin a in hemodialysis: a link between derangement of calcium-phosphorus homeostasis and progression of atherosclerosis?

scientific article published on 23 January 2009

Sirolimus and proteinuria in renal transplant patients: evidence for a dose-dependent effect on slit diaphragm-associated proteins.

scientific article published on May 2011

Soluble Serum αKlotho Is a Potential Predictive Marker of Disease Progression in Clear Cell Renal Cell Carcinoma

scientific article

Successful treatment of a facial attack of angioedema with icatibant in a patient with idiopathic angioedema.

scientific article published on 22 May 2013

TRPC6 mutations in children with steroid-resistant nephrotic syndrome and atypical phenotype.

scientific article

The ERA-EDTA Database on Recurrent Glomerulonephritis following renal transplantation.

scientific article published on 27 August 2013

The copy number variation landscape of congenital anomalies of the kidney and urinary tract

scientific article published on 21 December 2018

The pathogenesis of diabetic nephropathy: focus on microRNAs and proteomics.

scientific article published on 27 March 2013

The possible role of ChemR23/Chemerin axis in the recruitment of dendritic cells in lupus nephritis

scientific article published on 23 February 2011

The renal arterial resistance index: a marker of renal function with an independent and incremental role in predicting heart failure progression

scientific article published on 11 December 2013

The switch from proteasome to immunoproteasome is increased in circulating cells of patients with fast progressive immunoglobulin A nephropathy and associated with defective CD46 expression

scientific article published on 24 June 2020

Therapeutic apheresis in peripheral and retinal circulatory disorders.

scientific article published on June 2012

Uric acid: a starring role in the intricate scenario of metabolic syndrome with cardio-renal damage?

scientific article published on 13 August 2011

Urine protein profile of IgA nephropathy patients may predict the response to ACE-inhibitor therapy

scientific article published on 01 January 2008

Urine proteome analysis may allow noninvasive differential diagnosis of diabetic nephropathy ⬇️

scientific article

VHL gene alterations in Italian patients with isolated renal cell carcinomas

scientific article

Validation of the Oxford classification of IgA nephropathy in cohorts with different presentations and treatments

scientific article

Vasoactive intestinal polypeptide (VIP) is not an androgen-dependent neuromediator of penile erection.

scientific article published in January 2005

WT1 mutations in nephrotic syndrome revisited. High prevalence in young girls, associations and renal phenotypes

What would you like to eat, Mr CKD Microbiota? A Mediterranean Diet, please!

scientific article

miR-29b and miR-198 overexpression in CD8+ T cells of renal cell carcinoma patients down-modulates JAK3 and MCL-1 leading to immune dysfunction.

scientific article published on 11 April 2016

List of works by Loreto Gesualdo

A European multicentre and open-label controlled randomized trial to evaluate the efficacy of Sequential treatment with TAcrolimus-Rituximab versus steroids plus cyclophosphamide in patients with primary MEmbranous Nephropathy: the STARMEN study

A new model of acute care hospitals and the role of nephrologists

A novel SMARCAL1 mutation associated with a mild phenotype of Schimke immuno-osseous dysplasia (SIOD).

A pharmacoepidemiological study of the multi-level determinants, predictors, and clinical outcomes of biosimilar epoetin alfa for renal anaemia in haemodialysis patients: background and methodology of the MONITOR-CKD5 study.

A type I interferon signature characterizes chronic antibody-mediated rejection in kidney transplantation

Acquired lecithin:cholesterol acyltransferase deficiency as a major factor in lowering plasma HDL levels in chronic kidney disease

Albuminuria as a risk factor for mild cognitive impairment and dementia—what is the evidence?

Allograft nephrectomy: what is the best surgical technique?

Altered urinary excretion of aquaporin 2 in IgA nephropathy

Arteriovenous fistula stenosis in hemodialysis patients is characterized by an increased adventitial fibrosis

Author Correction: The copy number variation landscape of congenital anomalies of the kidney and urinary tract

CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS).

Clinical features and long-term outcome of nephrotic syndrome associated with heterozygous NPHS1 and NPHS2 mutations

Coagulation activation is associated with nicotinamide adenine dinucleotide phosphate oxidase-dependent reactive oxygen species generation in hemodialysis patients

Coexistence of different circulating anti-podocyte antibodies in membranous nephropathy.

Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pERK Signaling.

Complement Modulation of Anti-Aging Factor Klotho in Ischemia/Reperfusion Injury and Delayed Graft Function

Complement-dependent NADPH oxidase enzyme activation in renal ischemia/reperfusion injury

Copy-number disorders are a common cause of congenital kidney malformations

De novo homozygous mutation of the C1 inhibitor gene in a patient with hereditary angioedema

Defective gene expression of the membrane complement inhibitor CD46 in patients with progressive immunoglobulin A nephropathy.

Dexamethasone modulates interleukin-12 production by inducing monocyte chemoattractant protein-1 in human dendritic cells.

Diagnostic and prognostic role of preoperative circulating CA 15-3, CA 125, and beta-2 microglobulin in renal cell carcinoma.

Dialysis-related systemic microinflammation is associated with specific genomic patterns.

Dialysis-related transcriptomic profiling: the pivotal role of heparanase

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens

Downregulation of nuclear-encoded genes of oxidative metabolism in dialyzed chronic kidney disease patients

ERA-EDTA Immunonephrology working group

Early withdrawal of cyclosporine A improves 1-year kidney graft structure and function in sirolimus-treated patients.

Effect of Whole-Grain Barley on the Human Fecal Microbiota and Metabolome

Effect of an l-Carnitine–Containing Peritoneal Dialysate on Insulin Sensitivity in Patients Treated With CAPD: A 4-Month, Prospective, Multicenter Randomized Trial

Emerging biomarkers in renal damage

Endothelial dysfunction and renal fibrosis in endotoxemia-induced oliguric kidney injury: possible role of LPS-binding protein.

Endothelial-to-mesenchymal transition and renal fibrosis in ischaemia/reperfusion injury are mediated by complement anaphylatoxins and Akt pathway

Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome

Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations

Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations

Exposure to low- vs iso-osmolar contrast agents reduces NADPH-dependent reactive oxygen species generation in a cellular model of renal injury.

Fecal Microbiota Transplantation in Reducing Uremic Toxins Accumulation in Kidney Disease: Current Understanding and Future Perspectives

Focus on renal blood flow in mechanically ventilated patients with SARS-CoV-2: a prospective pilot study

Genetic Drivers of Kidney Defects in the DiGeorge Syndrome

Genome-wide analysis of differentially expressed genes and splicing isoforms in clear cell renal cell carcinoma

Hepatitis C virus-related proteins in kidney tissue from hepatitis C virus-infected patients with cryoglobulinemic membranoproliferative glomerulonephritis.

High dickkopf-1 levels in sera and leukocytes from children with 21-hydroxylase deficiency on chronic glucocorticoid treatment.

ID2-VEGF-related pathways in the pathogenesis of Kaposi's sarcoma: a link disrupted by rapamycin.

Impact of transplant nephrectomy on retransplantation: a single-center retrospective study.

Increasing relevance of donor-specific antibodies in antibody-mediated rejection.

Independent role of high central venous pressure in predicting worsening of renal function in chronic heart failure outpatients.

Ischemia-reperfusion injury-induced abnormal dendritic cell traffic in the transplanted kidney with delayed graft function

JAK3/STAT5/6 pathway alterations are associated with immune deviation in CD8 T cells in renal cell carcinoma patients.

Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients.

LPS removal reduces CD80-mediated albuminuria in critically ill patients with Gram-negative sepsis

LPS-Binding Protein Modulates Acute Renal Fibrosis by Inducing Pericyte-to-Myofibroblast Trans-Differentiation through TLR-4 Signaling

Local synthesis of interferon-alpha in lupus nephritis is associated with type I interferons signature and LMP7 induction in renal tubular epithelial cells.

Mechanisms of enhanced osteoclastogenesis in girls and young women with Turner's Syndrome

Microbiota and metabolome associated with immunoglobulin A nephropathy (IgAN).

Mutational Spectrum of CYP24A1 Gene in a Cohort of Italian Patients with Idiopathic Infantile Hypercalcemia.

Mutations in DSTYK and dominant urinary tract malformations

NLRP3 inflammasome activation in dialyzed chronic kidney disease patients

Neuropeptide Y as a risk factor for cardiorenal disease and cognitive dysfunction in chronic kidney disease: translational opportunities and challenges

Nocturnal haemodialysis is associated with a reduced occurrence of low triiodothyronine serum levels in haemodialysed patients

Novel INF2 mutations in an Italian cohort of patients with focal segmental glomerulosclerosis, renal failure and Charcot-Marie-Tooth neuropathy

Occipital sources of resting-state alpha rhythms are related to local gray matter density in subjects with amnesic mild cognitive impairment and Alzheimer's disease

Occult HBV infection in hemodialysis setting is marked by presence of isolated antibodies to HBcAg and HCV.

Osteoclastogenic potential of peripheral blood mononuclear cells in cleidocranial dysplasia

Paraneoplastic focal segmental glomerulosclerosis in sarcomatoid renal cell cancer.

Percutaneous ultrasound-guided renal biopsy in supine antero-lateral position: a new approach for obese and non-obese patients

Posttransplant Recurrence of Proteinuria in a Case of Focal Segmental Glomerulosclerosis Associated with WT1 Mutation

Pre-existing type 2 diabetes mellitus is an independent risk factor for mortality and progression in patients with renal cell carcinoma.

Preservation of renal function in atypical hemolytic uremic syndrome by eculizumab: a case report

Prevalence and cardiovascular risk profile of chronic kidney disease in Italy: results of the 2008-12 National Health Examination Survey

Proteinuria: from molecular to clinical applications in glomerulonephritis.

Purification and identification of peptides with high angiotensin-I converting enzyme (ACE) inhibitory activity from honeybee pupae (Apis mellifera) hydrolysates with in silico gastrointestinal digestion

Rapamycin for treatment of type I autosomal dominant polycystic kidney disease (RAPYD-study): a randomized, controlled study

Rapamycin induces ILT3(high)ILT4(high) dendritic cells promoting a new immunoregulatory pathway

Renal angiomyolipomatosis and Kaposi's sarcoma: a possible link disrupted by sirolimus.

Renal lesions in patients with type 2 diabetes: a puzzle waiting to be solved

Risk-based individualisation of target haemoglobin in haemodialysis patients with renal anaemia in the post-TREAT era: theoretical attitudes versus actual practice patterns (MONITOR-CKD5 study).

Serum fetuin a in hemodialysis: a link between derangement of calcium-phosphorus homeostasis and progression of atherosclerosis?