Search filters

List of works by Andrew George

A CIITA-independent pathway that promotes expression of endogenous rather than exogenous peptides in immune-privileged sites

scientific article published on 01 February 2004

A bacterially expressed single-chain Fv construct from the 2B4 T-cell receptor.

scientific article

A kinetic differentiation model for the action of altered TCR ligands.

scientific article

A method for determining the cytoprotective effect of catalase in transiently transfected cell lines and in corneal tissue.

scientific article published on February 1999

A novel strategy for preserving renal grafts in anex vivosetting: potential for enhancing the marginal donor pool

scientific article published on August 9, 2013

A rapid method for labelling CD4+ T cells with ultrasmall paramagnetic iron oxide nanoparticles for magnetic resonance imaging that preserves proliferative, regulatory and migratory behaviour in vitro.

scientific article published on 12 July 2006

A sensitive fluorometric assay for determining hydrogen peroxide-mediated sublethal and lethal endothelial cell injury.

scientific article published on January 1998

Absence of immunogenicity of diaspirin cross-linked hemoglobin in humans

scientific article published on 01 January 1998

Activated T cells modulate immunosuppression by embryonic-and bone marrow-derived mesenchymal stromal cells through a feedback mechanism

scientific article published on 05 December 2011

Adeno-associated and herpes simplex viruses as vectors for gene transfer to the corneal endothelium

article

Adenovirus-mediated gene delivery to the corneal endothelium.

scientific article

An approach to modelling in immunology.

scientific article

Analysis of soluble HLA Class II antigenic material in patients with immunological diseases using monoclonal antibodies

scientific article published in February 1986

Anti-LFA-1 monotherapy prevents neointimal formation in a murine model of transplant intimal hyperplasia

scientific article published on 01 July 2007

Anti-idiotypic therapy of leukemias and lymphomas.

scientific article published on January 1990

Anti-neutrophil cytoplasmic antibodies (ANCA) from patients with systemic vasculitis recognize restricted epitopes of proteinase 3 involving the catalytic site

scientific article

Antibody engineering

scientific article published on 01 January 1994

Antibody engineering: comparison of bacterial, yeast, insect and mammalian expression systems.

scientific article published in July 1998

Antibody targeted gene transfer to endothelium.

scientific article published in April 2003

Application of Phage Display Technology to Endothelial Cell Immunobiology.

scientific article

Applications of monoclonal antibodies in clinical oncology

scientific article published on 01 December 1994

Arginine depletion as a mechanism for the immune privilege of corneal allografts.

scientific article

Aspirin modified dendritic cells are potent inducers of allo-specific regulatory T-cells

scientific article (publication date: 20 December 2006)

Aspirin-treated human DCs up-regulate ILT-3 and induce hyporesponsiveness and regulatory activity in responder T cells

scientific article (publication date: September 2006)

Cell cycle modulation of gene targeting by a triple helix-forming oligonucleotide.

scientific article

Changing viral tropism using immunoliposomes alters the stability of gene expression: implications for viral vector design.

scientific article

Characterisation of a light chain loss variant of the BCL1 lymphoma

scientific article published in July 1991

Characterization of a new monoclonal anti-Fcγ RII antibody, AT10, and its incorporation into a bispecific F(ab′)2 derivative for recruitment of cytotoxic effectors

scientific article published on November 1, 1991

Characterization of autoantibodies from patients with Goodpasture's disease using a resonant mirror biosensor

scientific article published on 01 June 2002

Comparison of HIV-1 and EIAV-based lentiviral vectors in corneal transduction.

scientific article published on 21 January 2005

Corneal transplantation: the forgotten graft.

scientific article published on May 2004

Cytokine and chemokine expression kinetics after corneal transplantation

scientific article published on 01 October 2000

Cytokines, chaos, and complexity.

scientific article

Delivery of oligodeoxynucleotides into human saphenous veins and the adjunct effect of ultrasound and microbubbles.

scientific article published in December 2005

Delivery of the ribosome-inactivating protein, gelonin, to lymphoma cells via CD22 and CD38 using bispecific antibodies

scientific article published on May 1995

Demonstration of IgM antibodies of high affinity within the anti-Galalpha1-3Gal antibody repertoire.

scientific article

Dendritic cells in cancer immunotherapy. 10 January 2005, London, UK

scientific article published on 01 February 2005

Detection of vascular expression of E-selectin in vivo with MR imaging.

scientific article published on 27 September 2006

Development of a novel recombinant biotherapeutic with applications in targeted therapy of human arthritis

article

Differential effects of costimulatory pathway modulation on corneal allograft survival

scientific article published on 01 August 2006

Disease susceptibility, transplantation and the MHC

scientific article published on 01 May 1995

Distribution of integrins alpha v beta 5, alpha v beta 3 and alpha v in normal human cornea: possible implications in clinical and therapeutic adenoviral infection.

scientific article published on January 1998

Early treatment with xenon protects against the cold ischemia associated with chronic allograft nephropathy in rats

scientific article published on 11 September 2013

Effect of administration of CTLA4-Ig as protein or cDNA on corneal allograft survival

article

Engineered antibodies take center stage

scientific article

Epitope analysis of the Goodpasture antigen using a resonant mirror biosensor

scientific article published on 01 October 1996

Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea.

scientific article

Exploring and exploiting the antibody and Ig superfamily combining sites

scientific article published on May 1, 1996

Expression of recombinant anti-E-selectin single-chain Fv antibody fragments in stably transfected insect cell lines.

scientific article published in March 1998

Expression of the chemokine antagonist vMIP II using a non-viral vector can prolong corneal allograft survival.

scientific article

Expression of vascular cell adhesion molecule-1 by vascular endothelial cells in immune and nonimmune inflammatory reactions in the skin

scientific article published on 01 November 1997

Feedback control of T-cell receptor activation.

scientific article published in May 2004

Gene delivery by dendrimers operates via different pathways in different cells, but is enhanced by the presence of caveolin.

scientific article published on 14 July 2006

Gene delivery to the corneal endothelium

scientific article

Gene therapy for clinical transplantation: where do we stand in 2006?

scientific article published on August 2006

Gene transfer to ex vivo stored corneas

scientific article published on 01 July 1997

Goodpasture's disease in the absence of circulating anti-glomerular basement membrane antibodies as detected by standard techniques

scientific article published on 01 June 2002

Humoral effector mechanisms in the immunity to cancer

scientific article published in January 1990

Hydrophobic modification of low molecular weight polyethylenimine for improved gene transfection.

scientific article published on 21 July 2013

Identification of homing peptides specific for human synovium by in vivo phage display selection.

scientific article published on 24 February 2003

Identification of synovium-specific homing peptides by in vivo phage display selection.

scientific article

Idiotypic vaccination against B-cell lymphoma leads to dormant tumour

scientific article published in January 1991

Immune modulation in corneal transplantation.

scientific article published in April 2008

Importance of the linker in expression of single-chain Fv antibody fragments: optimisation of peptide sequence using phage display technology

scientific article published on June 23, 1997

In vivo selection of sFv from phage display libraries

scientific article

Indium-111 labelled lymphocytes: isotope distribution and cell division

scientific article published on 01 May 1997

Induction of tumor-specific T-cell responses by vaccination with tumor lysate-loaded dendritic cells in colorectal cancer patients with carcinoembryonic-antigen positive tumors

article

Inhibition of expression of the Galalpha1-3Gal epitope on porcine cells using an intracellular single-chain antibody directed against alpha1,3galactosyltransferase

scientific article

Intra-thecal treatment of leptomeningeal lymphoma with immunotoxin.

scientific article published on April 1991

Intrathymic function of the human cortical epithelial cell surface antigen gp200-MR6: single-chain antibodies to evolutionarily conserved determinants disrupt mouse thymus development

scientific article

Is the number of genes we possess limited by the presence of an adaptive immune system?

scientific article

Isolating ligands specific for human vasculature using in vivo phage selection

scientific article

Jumping or walking: which is better?

scientific article published on 01 January 2000

Knockdown of mouse VCAM-1 by vector-based siRNA.

scientific article published on September 2006

Lipoadenofection-mediated gene delivery to the corneal endothelium: prospects for modulating graft rejection

article

Local bioactive tumour necrosis factor (TNF) in corneal allotransplantation

scientific article published on 01 October 2000

Macromolecular synthetic biomaterials for delivery of therapeutics

scientific article published on 01 July 2010

Measurement of kinetic binding constants of a panel of anti-saporin antibodies using a resonant mirror biosensor

scientific article published on 01 June 1995

Modulation of costimulation by CD28 and CD154 alters the kinetics and cellular characteristics of corneal allograft rejection.

scientific article published in September 2003

Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy.

scientific article published on 25 January 2005

Modulation of hydrogen peroxide induced injury to corneal endothelium by virus mediated catalase gene transfer.

scientific article

Monitoring antibody responses to cancer vaccination with a resonant mirror biosensor

scientific article published on 01 March 1999

Novel triblock oligopeptides as efficient nonviral vectors: characterisation and further insights

scientific article published on 20 May 2010

Oligopeptide-mediated gene transfer into mouse corneal endothelial cells: expression, design optimization, uptake mechanism and nuclear localization.

scientific article published on 19 August 2009

Ovarian cancer immunotherapy using PD-L1 siRNA targeted delivery from folic acid-functionalized polyethylenimine: strategies to enhance T cell killing.

scientific article

Peptide-mediated non-viral gene transfer for transplantation

scientific article published on 01 March 2000

Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells.

scientific article published in April 2004

Programmed death ligand-1 over-expression correlates with malignancy and contributes to immune regulation in ovarian cancer

scientific article published on 3 December 2013

Radiometal labeling of recombinant proteins by a genetically engineered minimal chelation site: technetium-99m coordination by single-chain Fv antibody fusion proteins through a C-terminal cysteinyl peptide.

scientific article

Receptor editing during affinity maturation

scientific article published on 01 April 1999

Reconstruction of cell population dynamics using CFSE

scientific article

Redesigned anti-human placental alkaline phosphatase single-chain Fv: soluble expression, characterization and in vivo tumour targeting

scientific article published on 01 January 1997

Redirection of T cell-mediated cytotoxicity by a recombinant single-chain Fv molecule

scientific article published on 01 February 1994

Regulation of indoleamine 2,3-dioxygenase in primary human saphenous vein endothelial cells

scientific article published on 21 May 2015

Research governance at the crossroads

scientific article published on 01 February 2002

Research training and Calman reforms: a role for the MSc?

scientific article published in June 1996

Role of Toll-like receptor-4 in renal graft ischemia-reperfusion injury.

scientific article published on 12 February 2014

Selection of antibodies to cell surface determinants on mouse thymic epithelial cells using a phage display library

scientific article published on July 1, 1997

Single-chain Fv radioimmunotargeting.

scientific article published on September 1996

Smooth muscle cell proliferation but not neointimal formation is dependent on alloantibody in a murine model of intimal hyperplasia

scientific article published on 01 December 2006

Source of oncofetal ED-B-containing fibronectin: implications of production by both tumor and endothelial cells.

scientific article

Suppression of the allogeneic response by the anti‐allergy drug N‐(3,4‐dimethoxycinnamonyl) anthranilic acid results from T‐cell cycle arrest

scientific article published on February 1, 2013

Surface-bound cytokines--a possible effector-mechanism in bacterial immunity

scientific article published on 01 February 1994

Synthesis and in vitro evaluation of [18F]fluoroethyl triazole labelled [Tyr3]octreotate analogues using click chemistry.

scientific article published on 30 March 2011

T-lymphocyte invasiveness: control by voltage-gated Na+ channel activity.

scientific article published in July 2004

TNF receptor secretion after ex vivo adenoviral gene transfer to cornea and effect on in vivo graft survival.

scientific article published in June 2001

Targeted cytokine production

scientific article published on January 1992

Targeting gene delivery to activated vascular endothelium using anti E/P-Selectin antibody linked to PAMAM dendrimers.

scientific article

Targeting of anti-tumor responses with bispecific antibodies.

scientific article published on August 1992

The antibody molecule

scientific article published on 01 January 2000

The evolving role of gene-based treatment in surgery.

scientific article

The glycophosphatidylinositol anchor affects the conformation of Thy-1 protein

scientific article published on 01 February 1995

The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family

scientific article

The histidine utilization (hut) genes of Pseudomonas fluorescens SBW25 are active on plant surfaces, but are not required for competitive colonization of sugar beet seedlings

scientific article published in June 2006

The kinetics of MHC class I and class II expression in rat renal allografts

scientific article published on 01 April 1996

Thymic involution with ageing: obsolescence or good housekeeping?

scientific article

Tolerant T cells display impaired trafficking ability.

scientific article published in July 2005

Transplantation Society--XXth International Congress. 5-10 September 2004, Vienna, Austria.

scientific article published in November 2004

Understanding specificity and sensitivity of T-cell recognition.

scientific article

Upregulation of chemokine expression in murine cornea due to mechanical trauma or endotoxin.

scientific article published on 9 November 2007

Use of 2-[18F]fluoro-2-deoxyglucose as a potential agent in the prediction of graft rejection by positron emission tomography.

scientific article

Use of Biosensors to Measure the Kinetics of Antibody-Antigen Interactions

scientific article published on 01 January 2000

Xenon Treatment Protects against Remote Lung Injury after Kidney Transplantation in Rats.

scientific article

Xenon treatment attenuates early renal allograft injury associated with prolonged hypothermic storage in rats.

scientific article published on 12 June 2013

Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats.

scientific article published on 24 May 2013