List of works by Paul Fernyhough

A Brief Introduction to the History and Controversies of Clinical Trials in Diabetic Neuropathy.

scientific article

Acidic fibroblast growth factor enhances neurite outgrowth and stimulates expression of GAP-43 and T alpha 1 alpha-tubulin in cultured neurones from adult rat dorsal root ganglia

scientific article published on 01 September 1996

Activation of JNK in sensory neurons protects against sensory neuron cell death in diabetes and on exposure to glucose/oxidative stress in vitro.

scientific article published in December 2003

Activation of nuclear factor-kappaB via endogenous tumor necrosis factor alpha regulates survival of axotomized adult sensory neurons.

scientific article

An Introduction to the History and Controversies of Animal Models of Diabetic Neuropathy.

scientific article

An Introduction to the History and Controversies of the Pathogenesis of Diabetic Neuropathy.

scientific article published on 6 April 2016

Blockade of hexokinase activity and binding to mitochondria inhibits neurite outgrowth in cultured adult rat sensory neurons.

scientific article published on 31 January 2008

Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling

scientific journal article

Brain-derived neurotrophic factor mRNA levels are up-regulated in hindlimb skeletal muscle of diabetic rats: effect of denervation.

scientific article published in October 1996

Calcium signalling in sensory neurones and peripheral glia in the context of diabetic neuropathies.

scientific article

Changes in nerve growth factor and preprotachykinin messenger RNA levels in the iris and trigeminal ganglion in diabetic rats; effects of treatment with insulin or nerve growth factor.

scientific article published in March 1995

Ciliary neurotrophic factor activates NF-κB to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin-induced diabetic rodents.

scientific article

Ciliary neurotrophic factor reverses aberrant mitochondrial bioenergetics through the JAK/STAT pathway in cultured sensory neurons derived from streptozotocin-induced diabetic rodents.

scientific article published on 30 March 2014

Contraction-induced muscle fiber damage is increased in soleus muscle of streptozotocin-diabetic rats and is associated with elevated expression of brain-derived neurotrophic factor mRNA in muscle fibers and activated satellite cells

scientific article published on 01 February 2000

Deficits in sciatic nerve neuropeptide content coincide with a reduction in target tissue nerve growth factor messenger RNA in streptozotocin-diabetic rats: effects of insulin treatment

scientific article published on 01 September 1994

Development of iPSC-based clinical trial selection platform for patients with ultrarare diseases

scientific article published on 08 April 2022

Diabetes and axotomy-induced deficits in retrograde axonal transport of nerve growth factor correlate with decreased levels of p75LNTR protein in lumbar dorsal root ganglia.

scientific article published in November 1997

Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons

scientific article

Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats ⬇️

scientific article published on September 28, 2010

Effect of nerve growth factor treatment on p75NTR gene expression in lumbar dorsal root ganglia of streptozocin-induced diabetic rats

scientific article published on 01 November 1998

Effect of sciatic nerve crush on local and target tissue production of neurotrophin-3 transcripts in rats

scientific article published on 01 August 1998

Elevated expression of neurotrophin-3 mRNA in sensory nerve of streptozotocin-diabetic rats

scientific article published on 01 March 1999

Emerson enhancement, photosynthetic control and protein phosphorylation in isolated maize mesophyll chloroplasts; dependence upon carbon metabolism

scholarly article by Peter Horton et al published June 1990 in BBA - Bioenergetics

Expression of hexokinase isoforms in the dorsal root ganglion of the adult rat and effect of experimental diabetes

scientific article published in October 2007

Expression of neuropeptides in experimental diabetes; effects of treatment with nerve growth factor or brain-derived neurotrophic factor

scientific article published on 01 January 1994

Focally administered nerve growth factor suppresses molecular regenerative responses of axotomized peripheral afferents in rats

scientific article published on 01 January 1999

Functional magnetic resonance imaging of the spinal cord during sensory stimulation in diabetic rats

scientific article published on August 2009

Gentisic acid sodium salt, a phenolic compound, is superior to norepinephrine in reversing cardiovascular collapse, hepatic mitochondrial dysfunction and lactic acidemia in Pseudomonas aeruginosa septic shock in dogs.

scientific article published on 26 July 2016

Growth factors as therapeutics for diabetic neuropathy.

scientific article published on January 2008

Guaifenesin derivatives promote neurite outgrowth and protect diabetic mice from neuropathy

scientific article published on 13 June 2013

Human recombinant nerve growth factor replaces deficient neurotrophic support in the diabetic rat

scientific article published on 01 May 1995

Increase in the level of thylakoid protein phosphorylation in maize mesophyll chloroplasts by decrease in the transthylakoid pH gradient

scientific article published in 1984

Increased nerve growth factor mRNA in lateral calf skin biopsies from diabetic patients

scientific article published on 01 February 1999

Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones.

scientific article

Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons.

scientific article published in January 2005

Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia.

scientific article published in August 2003

Mechanisms of disease: Mitochondrial dysfunction in sensory neuropathy and other complications in diabetes.

scientific article

Mitochondrial dysfunction in diabetic neuropathy: a series of unfortunate metabolic events.

scientific article

Mitochondrial dysfunction in rabies virus infection of neurons

scientific article published on 26 November 2013

Mitochondrial malfunction and Ca2+ dyshomeostasis drive neuronal pathology in diabetes.

scientific article published on 11 January 2008

Mitochondrial respiratory chain dysfunction in dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatment

scientific article

Mitochondrial stress and the pathogenesis of diabetic neuropathy

scientific article

Nerve growth factor and neurotrophin-3 enhance neurite outgrowth and up-regulate the levels of messenger RNA for growth-associated protein GAP-43 and T alpha 1 alpha-tubulin in cultured adult rat sensory neurones

scientific article published on 01 February 1995

Nerve growth factor modulates the activation status and fast axonal transport of ERK 1/2 in adult nociceptive neurones

scientific article published on 01 August 2001

Nerve growth factor modulates tubulin transcript levels in pheochromocytoma PC12 cells

scientific article published on 01 October 1987

Nerve growth factor treatment of adult rats selectively enhances innervation of urinogenital tract rather than vascular smooth muscle.

scientific article published in August 1995

Neuronal survival in the balance: are endoplasmic reticulum membrane proteins the fulcrum?

scientific article

Neurotrophin-3 prevents the proximal accumulation of neurofilament proteins in sensory neurons of streptozocin-induced diabetic rats.

scientific article published in September 2003

New Directions in Diabetic Neuropathy: Evolution or Extinction?

scientific article published on 5 April 2016

Peripheral axon crush elevates transport of p75NTR in the central projection of sensory neurones of rats

scientific article published on 01 November 2003

Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab)

scientific article

Preconditioning injury-induced neurite outgrowth of adult rat sensory neurons on fibronectin is mediated by mobilisation of axonal α5 integrin

scientific article published on 06 March 2007

Rabies virus phosphoprotein interacts with mitochondrial Complex I and induces mitochondrial dysfunction and oxidative stress

scientific article

Receptor for advanced glycation end-products (RAGE) activates divergent signaling pathways to augment neurite outgrowth of adult sensory neurons.

scientific article

Role of oxidative stress in rabies virus infection

scientific article published on January 2011

Role of oxidative stress in rabies virus infection of adult mouse dorsal root ganglion neurons

scientific article published on 24 February 2010

Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy

scientific article

Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria.

scientific article published on 8 December 2015

Stabilization of tubulin mRNAs by insulin and insulin-like growth factor I during neurite formation

scientific article published on 01 November 1989

Target tissue production and axonal transport of neurotrophin-3 are reduced in streptozotocin-diabetic rats

scientific article published on 01 March 1998

Temporal dystrophic remodeling within the intrinsic cardiac nervous system of the streptozotocin-induced diabetic rat model

scientific article

The influence of metabolic state on the level of phosphorylation of the light-harvesting chlorophyll-protein complex in chloroplasts isolated from maize mesophyll

The proinflammatory cytokine, interleukin-17A, augments mitochondrial function and neurite outgrowth of cultured adult sensory neurons derived from normal and diabetic rats.

scientific article

Topical delivery of muscarinic receptor antagonists prevents and reverses peripheral neuropathy in female diabetic mice

scientific article published on 23 April 2020

Tumor necrosis factor-α elevates neurite outgrowth through an NF-κB-dependent pathway in cultured adult sensory neurons: Diminished expression in diabetes may contribute to sensory neuropathy

scientific article published on 22 September 2011

Xestospongin C empties the ER calcium store but does not inhibit InsP3-induced Ca2+ release in cultured dorsal root ganglia neurones.

scientific article

α7 integrin mediates neurite outgrowth of distinct populations of adult sensory neurons

scientific article published in February 2005

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