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List of works by Sergio Roa

AIDing antibody diversity by error-prone mismatch repair

scientific article

Crosstalk between genetic and epigenetic information through cytosine deamination

scientific article

Detailed Exploration around 4-Aminoquinolines Chemical Space to Navigate the Lysine Methyltransferase G9a and DNA Methyltransferase Biological Spaces

scientific article published on 19 July 2018

Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy

scientific article published on 19 July 2018

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

scientific article

Does antisense make sense of AID targeting?

scholarly article

Downregulation of FOXP1 is required during germinal center B-cell function.

scientific article published on 11 April 2013

Genome-wide expression profiling of B lymphocytes reveals IL4R increase in allergic asthma.

scientific article published on 26 June 2014

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

scientific article

IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions

scientific article

Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells ⬇️

scientific article published on September 23, 2011

LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas.

scientific article

MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites

scientific article

Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes

scientific article published on 10 June 2013

Mismatch-mediated error prone repair at the immunoglobulin genes

scientific article published on 24 October 2011

Molecular Genetics and Cytogenetics in Cancer ⬇️

scientific article published on January 1, 2011

Molecular analysis of activation-induced cytidine deaminase gene in immunoglobulin-E deficient patients.

scientific article published on January 2008

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas

scientific article published on 11 April 2019

Quantitative analysis of bcl-2 expression in normal and leukemic human B-cell differentiation

scientific article published on 01 March 2004

Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukemia

scientific article published on 21 February 2018

SHMTool: a webserver for comparative analysis of somatic hypermutation datasets

scientific article

The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination

scientific article published on 26 March 2012

The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination

scientific journal article

The multidimensional nature of epigenetic information and its role in disease

scientific article published on March 1, 2011

YRNAs overexpression and potential implications in allergy

scientific article published on 26 July 2019

miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma.

scientific article published on 10 February 2017

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