Search filters

List of works by Donald E. Ingber

A Biologically Inspired, Functionally Graded End Effector for Soft Robotics Applications

scientific article published on 12 October 2017

A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood

scientific article published on 13 June 2016

A Wnt-Bmp Feedback Circuit Controls Intertissue Signaling Dynamics in Tooth Organogenesis

scientific article published on January 10, 2012

A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling

scientific article

A combinatorial cell-laden gel microarray for inducing osteogenic differentiation of human mesenchymal stem cells

scientific article published on 29 January 2014

A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells

scientific article published on March 28, 2012

A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip

scientific article published on 13 May 2019

A computational tensegrity model predicts dynamic rheological behaviors in living cells

scientific article published on April 2004

A discrete cell cycle checkpoint in late G(1) that is cytoskeleton-dependent and MAP kinase (Erk)-independent

scientific article published in May 2002

A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane

scientific article published in February 1988

A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice

scientific article

A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics

scientific article published on 03 May 2021

A mathematical model to determine molecular kinetic rate constants under non-steady state conditions using fluorescence recovery after photobleaching (FRAP).

scientific article published on 4 November 2005

A mechanosensitive transcriptional mechanism that controls angiogenesis

scientific article

A microstructural approach to cytoskeletal mechanics based on tensegrity

scientific article published in July 1996

A mini-microscope for in situ monitoring of cells

scientific article

A multi-modular tensegrity model of an actin stress fiber

scientific article published on 15 July 2008

A non-genetic basis for cancer progression and metastasis: self-organizing attractors in cell regulatory networks

scientific article published on January 2006

A possible mechanism for inhibition of angiogenesis by angiostatic steroids: induction of capillary basement membrane dissolution

scientific article published in October 1986

A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function

scientific article

AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage

scientific article published on 02 December 2019

ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells

scientific article

Ablation of cytoskeletal filaments and mitochondria in live cells using a femtosecond laser nanoscissor

scientific article published in January 2005

Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells

scientific article published on 07 April 2008

Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway

scientific article

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy

scientific article

Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown

scientific article

Adhesion-dependent control of matrix metalloproteinase-2 activation in human capillary endothelial cells

scientific article published in November 2000

Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain

scientific article

An antifouling coating that enables affinity-based electrochemical biosensing in complex biological fluids

scientific article published on 11 November 2019

An improved mathematical approach for determination of molecular kinetics in living cells with FRAP.

scientific article published in September 2004

Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo

scientific journal article

Angiostatic steroids. Method of discovery and mechanism of action

scientific article

Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size

scientific article published in November 2000

Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale.

scientific article published on 18 October 2017

Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium

scientific article

Author Correction: A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip

scientific article published on 01 July 2019

Author Correction: On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology

scientific article published on 12 February 2020

Basement membrane as a spatial organizer of polarized epithelia. Exogenous basement membrane reorients pancreatic epithelial tumor cells in vitro.

scientific article

Bioinspired design and optimization for thin film wearable and building cooling systems

Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis

scientific article published on 13 April 2015

Biomechanics: cell research and applications for the next decade

scientific article

Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro

scientific article published on 4 May 2014

Breast cancer normalization induced by embryonic mesenchyme is mediated by extracellular matrix biglycan

scientific article published on August 1, 2013

Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment

scientific article published on 25 January 2019

Caldesmon-dependent switching between capillary endothelial cell growth and apoptosis through modulation of cell shape and contractility

scientific article published on January 1, 2003

Can cancer be reversed by engineering the tumor microenvironment?

scientific article published on April 2008

Cancer as a disease of epithelial-mesenchymal interactions and extracellular matrix regulation

scientific article

Carbon metabolism-mediated myogenic differentiation

scientific article published on 17 January 2010

Cell shape provides global control of focal adhesion assembly

scientific article (publication date: July 2003)

Cell surface properties of normal, differentiating, and neoplastic pancreatic acinar cells

scientific article

Cell tension, matrix mechanics, and cancer development

scientific article

Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels

scientific article published in February 2006

Cellular control lies in the balance of forces

scientific article published on April 1, 1998

Cellular mechanotransduction: putting all the pieces together again

scientific article

Cellular nanoscale stiffness patterns governed by intracellular forces

scientific article published on 17 June 2019

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton.

scientific article published on March 1993

Cellular tensegrity: exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis.

scientific article published on January 1994

Clear castable polyurethane elastomer for fabrication of microfluidic devices

scientific article published on October 2013

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device

scientific article published on 30 August 2016

Combined microfluidic-micromagnetic separation of living cells in continuous flow

scientific article published in December 2006

Commendation for Exposing Key Advantage of Organ Chip Approach

scientific article published in November 2016

Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

scientific article

Control of Cyclin D1, p27Kip1, and Cell Cycle Progression in Human Capillary Endothelial Cells by Cell Shape and Cytoskeletal Tension

scientific article published on November 1, 1998

Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension

scientific article

Control of cancer formation by intrinsic genetic noise and microenvironmental cues

scientific article published on 09 July 2015

Control of capillary growth and differentiation by extracellular matrix. Use of a tensegrity (tensional integrity) mechanism for signal processing

scientific article published on March 1991

Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension

scientific article

Control of embryonic lung branching morphogenesis by the Rho activator, cytotoxic necrotizing factor 1.

scientific article

Control of intracellular pH and growth by fibronectin in capillary endothelial cells

scientific article

Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics

scientific article published on January 1, 2013

Controlling Mammalian Cell Spreading and Cytoskeletal Arrangement with Conveniently Fabricated Continuous Wavy Features on Poly(dimethylsiloxane)

Controlling cell attachment on contoured surfaces with self-assembled monolayers of alkanethiolates on gold

scientific article published on October 1996

Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex

scientific article

Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells

scientific article

Cytoskeletal control of growth and cell fate switching

scientific article published on 08 September 2009

Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470).

scientific article published on February 1994

Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure

scientific article

Developing microphysiological systems for use as regulatory tools--challenges and opportunities

scientific article published on January 2014

Developmentally inspired human 'organs on chips'

scientific article published on 18 May 2018

Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation

scientific article published on 18 February 2014

Direct Bonding of Chitosan Biomaterials to Tissues Using Transglutaminase for Surgical Repair or Device Implantation

scientific article published on 21 November 2016

Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation

scientific article published on 7 January 2008

Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces

scientific article published on August 2002

Discovery of potent and practical antiangiogenic agents inspired by cortistatin A.

scientific article published in July 2009

Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip

scientific article (publication date: 2016)

Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ-on-a-Chip

scientific article published on 14 March 2022

Electrically conducting polymers can noninvasively control the shape and growth of mammalian cells

scientific article

Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients

scientific article published on 26 August 2020

Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1

scientific journal article

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

scientific article published on 19 December 2011

Establishment of physiologically relevant oxygen gradients in microfluidic organ chips

scientific article published on 12 April 2022

Evidence by molecular profiling for a placental origin of infantile hemangioma

scientific article

Extracellular matrix and cell shape: potential control points for inhibition of angiogenesis

scientific article published on November 1, 1991

Extracellular matrix as a solid-state regulator in angiogenesis: identification of new targets for anti-cancer therapy

scientific article

Extracellular matrix controls myosin light chain phosphorylation and cell contractility through modulation of cell shape and cytoskeletal prestress

scientific article published in March 2004

Extracellular matrix controls tubulin monomer levels in hepatocytes by regulating protein turnover

scientific article published on December 1, 1994

Extracellular matrix, mechanotransduction and structural hierarchies in heart tissue engineering

scientific article published on August 2007

Fibronectin controls capillary endothelial cell growth by modulating cell shape

scientific article

Fibronectin unfolding revisited: modeling cell traction-mediated unfolding of the tenth type-III repeat

scientific article (publication date: 2008)

Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion

scientific article published on October 11, 2010

Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts

scientific article published on 16 January 2007

Force meets chemistry: analysis of mechanochemical conversion in focal adhesions using fluorescence recovery after photobleaching

scientific article

Forty-Year Journey of Angiogenesis Translational Research

scientific article published on December 21, 2011

From 3D cell culture to organs-on-chips

scientific article published on October 25, 2011

From cellular mechanotransduction to biologically inspired engineering: 2009 Pritzker Award Lecture, BMES Annual Meeting October 10, 2009.

scientific article

From mechanobiology to developmentally inspired engineering

scientific article published on 24 September 2018

Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles

scientific article published in November 2003

Generation of biocompatible droplets for in vivo and in vitro measurement of cell-generated mechanical stresses

scientific article published on 8 January 2015

Geometric control of cell life and death

scientific article (publication date: 30 May 1997)

Geometric determinants of directional cell motility revealed using microcontact printing

scientific article published on March 2003

Global cytoskeletal control of mechanotransduction in kidney epithelial cells

scientific article

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation

scientific article published on September 1, 2013

Heparin-binding angiogenesis factors: detection by immunological methods.

scientific article published in January 1987

Hepatocyte culture on biodegradable polymeric substrates

scientific article

High-betweenness proteins in the yeast protein interaction network

scientific article

How cells (might) sense microgravity

scientific article

How changes in extracellular matrix mechanics and gene expression variability might combine to drive cancer progression

scientific article

How does extracellular matrix control capillary morphogenesis?

scientific article

Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro

scientific article

Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip

Human Lung Small Airway-on-a-Chip Protocol

scientific article published in January 2017

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

scientific article published on 20 March 2012

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

scientific article published on September 1, 2013

Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies.

scientific article

Identification of a distinct class of cytoskeleton-associated mRNAs using microarray technology

scientific article

Impaired mechanical stability, migration and contractile capacity in vimentin deficient fibroblasts

scientific article published on July 1, 1998

Improved treatment of systemic blood infections using antibiotics with extracorporeal opsonin hemoadsorption

scientific article

In search of cellular control: signal transduction in context.

scientific article

Induction of angiogenesis during the transition from hyperplasia to neoplasia

scientific article

Inhibition of angiogenesis

scientific article published on April 1, 1992

Inhibition of angiogenesis through modulation of collagen metabolism.

scientific article published in July 1988

Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins

scientific article

Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix

scientific article

Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape

scientific article published on September 1, 1991

Intact Vinculin Protein Is Required for Control of Cell Shape, Cell Mechanics, and rac-Dependent Lamellipodia Formation

scientific article published on January 18, 2002

Integrating with integrins

scientific article

Integrin binding and cell spreading on extracellular matrix act at different points in the cell cycle to promote hepatocyte growth

scientific article

Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions

scientific article published on April 16, 1998

Integrin-dependent induction of early growth response genes in capillary endothelial cells.

scientific article published in December 1996

Integrins as mechanochemical transducers

scientific article published on October 1991

Integrins, tensegrity, and mechanotransduction.

scientific article

Interview with Donald E Ingber

scientific article published in May 2014

Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells

scientific article published on 2 July 2003

Intraductal injection for localized drug delivery to the mouse mammary gland

scientific article published on 04 October 2013

Investigating complexity of protein-protein interactions in focal adhesions

scientific article

Is cytoskeletal tension a major determinant of cell deformability in adherent endothelial cells?

scientific article published on May 1, 1998

Is it Time for Reviewer 3 to Request Human Organ Chip Experiments Instead of Animal Validation Studies?

scientific article published on 12 October 2020

LRP5 Regulates Development of Lung Microvessels and Alveoli through the Angiopoietin-Tie2 Pathway

scientific article published on July 25, 2012

Lab on a Chip: United States of America

scientific article published on May 16, 2012

Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton

scientific article

Low Urine Vascular Endothelial Growth Factor Levels Are Associated with Mechanical Ventilation, Bronchopulmonary Dysplasia and Retinopathy of Prematurity

scientific article published on May 24, 2013

Magnetic Cellular Switches

scientific article published on January 1, 2004

Magnetically-guided self-assembly of fibrin matrices with ordered nano-scale structure for tissue engineering

scientific article published on November 2006

Manufacturing of Large-Scale Functional Objects Using Biodegradable Chitosan Bioplastic

scholarly article by Javier G. Fernandez & Donald E. Ingber published 26 February 2014 in Macromolecular Materials and Engineering

Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip

scientific article published on 27 October 2016

Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip

article

Mechanical behavior in living cells consistent with the tensegrity model

scientific article published on July 2001

Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Galphas protein

scientific article published on March 2009

Mechanical control of cyclic AMP signalling and gene transcription through integrins

scientific article published on September 2000

Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip

scientific article published on 08 April 2022

Mechanical control of tissue and organ development

scientific article published on May 2010

Mechanical control of tissue growth: function follows form

scientific article

Mechanical control of tissue morphogenesis during embryological development

scientific article

Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells

scientific article published in April 2006

Mechanical induction of dentin-like differentiation by adult mouse bone marrow stromal cells using compressive scaffolds

scientific article published on 17 August 2017

Mechanical properties of individual focal adhesions probed with a magnetic microneedle

scientific article published in January 2004

Mechanical signaling

scientific article

Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology

scientific article

Mechanobiology and developmental control

scientific article published on January 2013

Mechanobiology and diseases of mechanotransduction

scientific article published on January 2003

Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation

scientific article published on 15 September 2011

Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix

scientific article

Mechanosensation through integrins: cells act locally but think globally

scholarly article

Mechanosensitive mechanisms in transcriptional regulation

scientific article published on July 13, 2012

Mechanotransduction Across the Cell Surface and Through the Cytoskeleton

scientific article published on May 21, 1993

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

scientific article published on January 2009

Mechanotransduction of fluid stresses governs 3D cell migration

scientific article

Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins

scientific article

Mesenchymal condensation-dependent accumulation of collagen VI stabilizes organ-specific cell fates during embryonic tooth formation

scientific article published on 24 April 2015

Metabolism of tumor regression from angiogenesis inhibition: 31P magnetic resonance spectroscopy

scientific article published in August 1989

Methods for measuring rates of protein binding to insoluble scaffolds in living cells: histone H1-chromatin interactions

scientific article published on December 2006

Methods for studying mechanical control of angiogenesis by the cytoskeleton and extracellular matrix

scientific article published on January 2008

Microfabrication of human organs-on-chips.

scientific article published on 10 October 2013

Microfluidic organs-on-chips

scientific article published in August 2014

Micromagnetic-microfluidic blood cleansing device

scientific article

Micromechanical control of cell and tissue development: implications for tissue engineering

scientific article published on 16 August 2007

Micropatterning tractional forces in living cells

scientific article

Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement

scientific article

Modeling Hematopoiesis and Responses to Radiation Countermeasures in a Bone Marrow-on-a-Chip

scientific article published on 18 March 2016

Modelling cancer in microfluidic human organs-on-chips

scientific article published on 01 February 2019

Models of cytoskeletal mechanics of adherent cells

scientific article published on June 1, 2002

Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape

scientific article published on 22 May 2018

Molecular mapping of transmembrane mechanotransduction through the β1 integrin-CD98hc-TRPV4 axis

scientific article published on 28 September 2020

Molecular signaling: breakout session summary

scientific article published in June 2002

Mononuclear cells from dedifferentiation of mouse myotubes display remarkable regenerative capability

scientific article published on September 2014

Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips

scientific article published in 2024

Multiple integrins share the ability to induce elevation of intracellular pH

article

Multistable and multistep dynamics in neutrophil differentiation

scientific article

Multizone paper platform for 3D cell cultures

scientific article (publication date: 6 May 2011)

Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment

scientific article published on 09 May 2014

Nanostructured magnetizable materials that switch cells between life and death

scientific article

Nanosurgery in live cells using ultrashort laser pulses

scholarly article published 15 April 2005

Neoplastic disorganization of pancreatic epithelial cell-cell relations. Role of basement membrane

scientific article published in November 1985

New anticoagulant coatings and hemostasis assessment tools to avoid complications with pediatric left ventricular assist devices

scientific article published on 24 April 2017

New role for tRNA and its fragment purified from human urinary bladder carcinoma conditioned medium: inhibition of endothelial cell growth

scientific article published on November 1999

Nogo-A is a negative regulator of CNS angiogenesis

scientific article

Noise-driven stem cell and progenitor population dynamics

scientific article published on 13 August 2008

Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy

scientific article published on 01 January 2019

Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry

scientific article published on 31 March 2005

On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology

scientific article published on 27 January 2020

Optimization of Pathogen Capture in Flowing Fluids with Magnetic Nanoparticles

scientific article published on 21 September 2015

Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems.

scientific article published on 27 February 2018

Organs on Chips 2013

scientific article published on September 21, 2013

Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities.

scientific article published on 13 June 2017

Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function

scientific article published on 9 June 2017

PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury

scientific article published on 17 January 2018

Paper-supported 3D cell culture for tissue-based bioassays

scientific article

Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems

scholarly article

Patterning proteins and cells using soft lithography

scientific article

Paxillin controls directional cell motility in response to physical cues

scientific article published on 17 October 2012

Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression

scientific article published on 12 February 2014

Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning

scientific article

Physiologically Based Pharmacokinetic and Pharmacodynamic Analysis Enabled by Microfluidically Linked Organs-on-Chips

scientific article published in January 2018

Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models

scientific article published on 01 February 2019

Platform for High-Throughput Testing of the Effect of Soluble Compounds on 3D Cell Cultures

scientific article published on August 16, 2013

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

scientific article

Polymeric Nanomaterials for Islet Targeting and Immunotherapeutic Delivery

scientific article published on December 28, 2011

Pre-stressed Tensegrity Structures built from DNA

scientific article published in February 2009

Programed Death is Favored by Natural Selection in Spatial Systems

scientific article

Proteomic and Metabolomic Characterization of Human Neurovascular Unit Cells in Response to Methamphetamine

scientific article published on 03 August 2020

Pulse energy dependence of subcellular dissection by femtosecond laser pulses

scientific article published in May 2005

Purified and recombinant hemopexin: protease activity and effect on neutrophil chemotaxis

scientific article published on 08 January 2016

Quantifying cell-generated mechanical forces within living embryonic tissues

scientific article

Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips

scientific article published on 27 January 2020

Rapid Coating Process Generates Omniphobic Dentures in Minutes to Reduce <i>C. albicans</i> Biofouling

scientific article published on 27 December 2018

Rapid Induction and Isolation of Focal Adhesion Complexes

scientific article published on June 15, 1993

Rapid Isolation of Staphylococcus aureus Pathogens from Infected Clinical Samples Using Magnetic Beads Coated with Fc-Mannose Binding Lectin

scientific article

Reconstituting organ-level lung functions on a chip

scientific article

Regulation of cytoskeletal mechanics and cell growth by myosin light chain phosphorylation.

scientific article published on November 1998

Reply: To PMID 23711562.

scientific article

Reproducing human and cross-species drug toxicities using a Liver-Chip

scientific article published on 01 November 2019

Reproductive endocrinology: Cycling through the menstrual cycle - an out-of-body experience

scientific article published on 26 May 2017

Reverse Engineering Human Pathophysiology with Organs-on-Chips

scientific article published in March 2016

Rheological behavior of living cells is timescale-dependent

scientific article

Rho signaling and mechanical control of vascular development

scientific article published on May 2008

Robotic fluidic coupling and interrogation of multiple vascularized organ chips

scientific article published on 27 January 2020

Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition

scientific article

Role of basal lamina in neoplastic disorganization of tissue architecture

scientific article

SLLISWD Sequence in the 10FNIII Domain Initiates Fibronectin Fibrillogenesis

scientific article published on 05 June 2013

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

scientific article published on 20 October 2018

Self-assembly of three-dimensional prestressed tensegrity structures from DNA.

scientific article published on 20 June 2010

Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope

scientific article

Shape-dependent control of cell growth, differentiation, and apoptosis: switching between attractors in cell regulatory networks

scientific article

Silencing HoxA1 by intraductal injection of siRNA lipidoid nanoparticles prevents mammary tumor progression in mice

scientific article

Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro

scientific article published on 21 December 2015

Soft lithography in biology and biochemistry

scientific article

Species-specific enhancement of enterohemorrhagic E. Coli pathogenesis mediated by microbiome metabolites

Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites

scientific article published on 20 March 2019

Stability of Surface-Immobilized Lubricant Interfaces under Flow

article by Caitlin Howell et al published 20 February 2015 in Chemistry of Materials

Symmetry-breaking in mammalian cell cohort migration during tissue pattern formation: role of random-walk persistence

scientific article published on August 2005

Synaptic reorganization in scaled networks of controlled size.

scientific article published in December 2007

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

scientific article published on December 6, 1990

TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling

scientific article

Targeted drug delivery to flow-obstructed blood vessels using mechanically activated nanotherapeutics

scientific article published on January 2015

Tensegrity I. Cell structure and hierarchical systems biology

scientific article

Tensegrity II. How structural networks influence cellular information processing networks

scientific article

Tensegrity and mechanoregulation: from skeleton to cytoskeleton

scientific article

Tensegrity and mechanotransduction

scientific article

Tensegrity, cellular biophysics, and the mechanics of living systems

scientific article

Tensegrity-based mechanosensing from macro to micro

scientific article published on 13 February 2008

Tensegrity: the architectural basis of cellular mechanotransduction

scientific article

Tensile forces stimulate vascular remodeling and epidermal cell proliferation in living skin

scientific article published in November 2007

The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway

scientific article

The Wyss Institute at Harvard University

scientific article published on July 1, 2011

The Wyss institute: A new model for medical technology innovation and translation across the academic-industrial interface

scientific article published on 5 September 2017

The architecture of life.

scientific article

The mechanochemical basis of cell and tissue regulation.

scientific article published on March 2004

The origin of cellular life

scientific article

The riddle of morphogenesis: a question of solution chemistry or molecular cell engineering?

scientific article published in December 1993

The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading

scientific article

The structural and mechanical complexity of cell-growth control

scientific article

Theory and associated phenomenology for intrinsic mortality arising from natural selection

scientific article

Tissue Engineering by Cell Transplantation Using Degradable Polymer Substrates

scientific article published on May 1, 1991

Tissue engineering and developmental biology: going biomimetic

scientific article published on December 2006

Tools to study cell mechanics and mechanotransduction

scientific article published in January 2007

Towards a holistic, yet gene-centered analysis of gene expression profiles: a case study of human lung cancers

scientific article

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

scientific article

Treatment of psoriasis with NFKBIZ siRNA using topical ionic liquid formulations

scientific article published on 22 July 2020

Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells

scientific article

Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier via Transcytosis

scientific article published on 10 September 2019

Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro

scholarly article

Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins

scientific article published on 20 August 2010

Ultrasound-sensitive nanoparticle aggregates for targeted drug delivery

scientific article published on 6 June 2017

Unexpected Strength and Toughness in Chitosan‐Fibroin Laminates Inspired by Insect Cuticle

scientific article published on December 13, 2011

Using Microcontact Printing to Pattern the Attachment of Mammalian Cells to Self-Assembled Monolayers of Alkanethiolates on Transparent Films of Gold and Silver

scientific article published on September 15, 1997

Using self-assembled monolayers to pattern ECM proteins and cells on substrates

scientific article

Vacuum-assisted closure: microdeformations of wounds and cell proliferation

scientific article

Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton

scientific article

What lies at the interface of regenerative medicine and developmental biology?

scientific article published on 6 June 2007

l-Caldesmon regulates proliferation and migration of vascular smooth muscle cells and inhibits neointimal formation after angioplasty

scientific article published on 03 August 2006

α-Actinin-4 Is Required for Normal Podocyte Adhesion

scientific article published in Journal of Biological Chemistry