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List of works by Demetrio J Santiago

A cryo-EM-based model of phosphorylation- and FKBP12.6-mediated allosterism of the cardiac ryanodine receptor.

scientific article

Arrhythmogenic Cardiomyopathy: Pathophysiology Beyond Cardiac Myocytes

scientific article published in December 2017

Ca sparks do not explain all ryanodine receptor-mediated SR Ca leak in mouse ventricular myocytes

scientific article

Calcium release near L-type calcium channels promotes beat-to-beat variability in ventricular myocytes from the chronic AV block dog.

scientific article published on 7 October 2015

Calcium/calmodulin-dependent kinase II and nitric oxide synthase 1-dependent modulation of ryanodine receptors during β-adrenergic stimulation is restricted to the dyadic cleft

scientific article published on 28 April 2016

Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics

scientific article published on 29 July 2020

Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant

scientific article published on September 2017

Isoproterenol increases the fraction of spark-dependent RyR-mediated leak in ventricular myocytes.

scientific article published on March 2013

Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation

scientific article

Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II.

scientific article published on 29 March 2010

The changes in Ca2+ sparks associated with measured modifications of intra-store Ca2+ concentration in skeletal muscle.

scientific article