List of works - Thomas Burmeister

A BACH2-BCL2L1 fusion gene resulting from a t(6;20)(q15;q11.2) chromosomal translocation in the lymphoma cell line BLUE-1.

scientific article published on 15 March 2011

A MLL-KIAA0284 fusion gene in a patient with secondary acute myeloid leukemia and t(11;14)(q23;q32).

scientific article

A PCR primer system for detecting oncoretroviruses based on conserved DNA sequence motifs of animal retroviruses and its application to human leukaemias and lymphomas.

scientific article published in September 2001

A multiplex PCR for improved detection of typical and atypical BCR–ABL fusion transcripts

scientific article published on 24 October 2007

A novel sporadic Burkitt lymphoma cell line (BLUE-1) with a unique t(6;20)(q15;q11.2) rearrangement

scientific article published on 11 May 2006

Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization

scientific article published on 15 February 2013

Atypical BCR-ABL mRNA transcripts in adult Acute lymphoblastic leukemia

BCR-ABL Mutation-Guided Therapy for CML Blast Crisis: A Case Report

scientific article published on 30 August 2015

BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features

scientific article published on 14 June 2016

BCR-ABL1(+) acute myeloid leukemia: clonal selection of a BCR-ABL1(-) subclone as a cause of refractory disease with nilotinib treatment

scientific article published on 12 November 2014

Burkitt Lymphoma

scientific article published in 2013

CD56 expression in T-cell acute lymphoblastic leukemia is associated with non-thymic phenotype and resistance to induction therapy but no inferior survival after risk-adapted therapy

scientific article published on 23 December 2008

Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations

scientific article published on 27 January 2012

Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia

scientific article

Combined automated cell and flow cytometric analysis enables recognition of persistent polyclonal B-cell lymphocytosis (PPBL), a study of 25 patients

scientific article published on 28 June 2008

Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4·MLL fusion allele

scientific article published on 05 April 2007

Corrigendum to ‘Evidence-based RT-PCR methods for the detection of the 8 most common MLL aberrations in acute leukemias’ [Leuk. Res. 39(2) (2015) 242–247]

article

Detection of subclinical systemic disease in primary CNS lymphoma by polymerase chain reaction of the rearranged immunoglobulin heavy-chain genes

scientific article published on 11 September 2006

EZH2: a pleiotropic protein

scientific article

Efficacy and pharmacologic data of second-generation tyrosine kinase inhibitor nilotinib in BCR-ABL-positive leukemia patients with central nervous system relapse after allogeneic stem cell transplantation

scientific article

Erroneous class switching and false VDJ recombination: molecular dissection of t(8;14)/MYC-IGH translocations in Burkitt-type lymphoblastic leukemia/B-cell lymphoma

scientific article published on 25 April 2013

Evidence-based RT-PCR methods for the detection of the 8 most common MLL aberrations in acute leukemias

scientific article published on 29 November 2014

Expression of interleukin 15 in primary adult acute lymphoblastic leukemia

scientific article published in January 2010

Expression of the human homologue of rat NG2 in adult acute lymphoblastic leukemia: close association with MLL rearrangement and a CD10(-)/CD24(-)/CD65s(+)/CD15(+) B-cell phenotype.

scientific article published on August 2003

FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors

scientific article

Fine structure of translocation breakpoints within the major breakpoint region in BCR-ABL1-positive leukemias

scientific article published on 22 September 2011

Flow cytometric maturity score as a novel prognostic parameter in patients with acute myeloid leukemia.

scientific article published on 22 May 2015

Germline variants in IKZF1, ARID5B, and CEBPE as risk factors for adult-onset acute lymphoblastic leukemia: an analysis from the GMALL study group

scientific article published on February 2014

High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia

scientific article published on 11 January 2010

High expression of the ETS transcription factor ERG predicts adverse outcome in acute T-lymphoblastic leukemia in adults.

scientific article published on 5 September 2006

High prevalence of immunoglobulin light chain gene aberrations as revealed by FISH in multiple myeloma and MGUS.

scientific article

Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia

scientific article

Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial

scientific article

Insertional polymorphisms of endogenous HERV-K113 and HERV-K115 retroviruses in breast cancer patients and age-matched controls

scientific article published in November 2004

Intrathecal application of donor lymphocytes in leukemic meningeosis after allogeneic stem cell transplantation

scientific article

Involvement of the MLL gene in adult T-lymphoblastic leukemia

scientific article published on 25 August 2012

Long distance polymerase chain reaction of ascites lymphoma cells aids diagnosis establishment of abdominal Burkitt's lymphoma and Burkitt-like lymphoma.

scientific article published in January 2005

Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL

Long-term relapse-free survival in a phase 2 study of blinatumomab for the treatment of patients with minimal residual disease in B-lineage acute lymphoblastic leukemia

scientific article published on 12 January 2017

Loss-of-function but not dominant-negative intragenic IKZF1 deletions are associated with an adverse prognosis in adult BCR-ABL-negative acute lymphoblastic leukemia

scientific article published on 27 July 2017

Low ERG and BAALC expression identifies a new subgroup of adult acute T-lymphoblastic leukemia with a highly favorable outcome

scientific article

MLL: exploring the methylome

scientific article published in June 2010

Melting point assay for the JAK2 V617F mutation, comparison with amplification refractory mutation system (ARMS) in diagnostic samples, and implications for daily routine.

scientific article published on June 2010

Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts

scientific article published on 23 September 2011

Molecular analysis of the t(2;8)/MYC-IGK translocation in high-grade lymphoma/leukemia by long-distance inverse PCR.

scientific article published on 25 November 2011

Molecular characterization and clinical course of MLL-ACTN4 rearrangement in therapy-related hematologic malignancies

scientific article published on 21 February 2014

Molecular heterogeneity of sporadic adult Burkitt-type leukemia/lymphoma as revealed by PCR and cytogenetics: correlation with morphology, immunology and clinical features.

scientific article

Molecular monitoring in NUP214-ABL-positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy.

scientific article

Molekulargenetik

Molekulargenetik bei Leukämien

Monitoring minimal residual disease by quantification of genomic chromosomal breakpoint sequences in acute leukemias with MLL aberrations.

scientific article published in March 2006

NUP214-ABL1 in adult T-ALL: the GMALL study group experience.

scientific article published on 27 July 2006

New insights to the MLL recombinome of acute leukemias

scientific article

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms

scientific article

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

scientific article published on 27 February 2014

Oncogenic retroviruses in animals and humans.

scientific article

Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia

scientific article published on 18 October 2011

PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia

scientific article published on 06 March 2019

Patients' age and BCR-ABL frequency in adult B-precursor ALL: a retrospective analysis from the GMALL study group

article

Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia

scientific article published on October 2009

Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia

scientific article

Randomized comparison of prophylactic and minimal residual disease-triggered imatinib after allogeneic stem cell transplantation for BCR-ABL1-positive acute lymphoblastic leukemia

scientific article published on 5 December 2012

Rapid and sensitive detection of calreticulin type 1 and 2 mutations by real-time quantitative PCR.

scientific article

Skewed expression of natural-killer (NK)-associated antigens on lymphoproliferations of large granular lymphocytes (LGL).

scientific article published in June 2006

Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia.

scientific article

Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival.

scientific article published on 16 May 2011

The MLL recombinome of acute leukemias

scientific article published on 01 May 2006

The MLL recombinome of acute leukemias in 2013.

scientific article

The MLL recombinome of acute leukemias in 2017.

scientific article published on 13 July 2017

The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group

scientific article published on 14 January 2009

Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group.

scientific article published on 27 March 2008

Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia.

scientific article

List of works by Thomas Burmeister

A BACH2-BCL2L1 fusion gene resulting from a t(6;20)(q15;q11.2) chromosomal translocation in the lymphoma cell line BLUE-1.

A MLL-KIAA0284 fusion gene in a patient with secondary acute myeloid leukemia and t(11;14)(q23;q32).

A PCR primer system for detecting oncoretroviruses based on conserved DNA sequence motifs of animal retroviruses and its application to human leukaemias and lymphomas.

A multiplex PCR for improved detection of typical and atypical BCR–ABL fusion transcripts

A novel sporadic Burkitt lymphoma cell line (BLUE-1) with a unique t(6;20)(q15;q11.2) rearrangement

Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization

Atypical BCR-ABL mRNA transcripts in adult Acute lymphoblastic leukemia

BCR-ABL Mutation-Guided Therapy for CML Blast Crisis: A Case Report

BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features

BCR-ABL1(+) acute myeloid leukemia: clonal selection of a BCR-ABL1(-) subclone as a cause of refractory disease with nilotinib treatment

Burkitt Lymphoma

CD56 expression in T-cell acute lymphoblastic leukemia is associated with non-thymic phenotype and resistance to induction therapy but no inferior survival after risk-adapted therapy

Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations

Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia

Combined automated cell and flow cytometric analysis enables recognition of persistent polyclonal B-cell lymphocytosis (PPBL), a study of 25 patients

Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4·MLL fusion allele

Corrigendum to ‘Evidence-based RT-PCR methods for the detection of the 8 most common MLL aberrations in acute leukemias’ [Leuk. Res. 39(2) (2015) 242–247]

Detection of subclinical systemic disease in primary CNS lymphoma by polymerase chain reaction of the rearranged immunoglobulin heavy-chain genes

EZH2: a pleiotropic protein

Efficacy and pharmacologic data of second-generation tyrosine kinase inhibitor nilotinib in BCR-ABL-positive leukemia patients with central nervous system relapse after allogeneic stem cell transplantation

Erroneous class switching and false VDJ recombination: molecular dissection of t(8;14)/MYC-IGH translocations in Burkitt-type lymphoblastic leukemia/B-cell lymphoma

Evidence-based RT-PCR methods for the detection of the 8 most common MLL aberrations in acute leukemias

Expression of interleukin 15 in primary adult acute lymphoblastic leukemia

Expression of the human homologue of rat NG2 in adult acute lymphoblastic leukemia: close association with MLL rearrangement and a CD10(-)/CD24(-)/CD65s(+)/CD15(+) B-cell phenotype.

FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors

Fine structure of translocation breakpoints within the major breakpoint region in BCR-ABL1-positive leukemias

Flow cytometric maturity score as a novel prognostic parameter in patients with acute myeloid leukemia.

Germline variants in IKZF1, ARID5B, and CEBPE as risk factors for adult-onset acute lymphoblastic leukemia: an analysis from the GMALL study group

High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia

High expression of the ETS transcription factor ERG predicts adverse outcome in acute T-lymphoblastic leukemia in adults.

High prevalence of immunoglobulin light chain gene aberrations as revealed by FISH in multiple myeloma and MGUS.

Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia

Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial

Insertional polymorphisms of endogenous HERV-K113 and HERV-K115 retroviruses in breast cancer patients and age-matched controls

Intrathecal application of donor lymphocytes in leukemic meningeosis after allogeneic stem cell transplantation

Involvement of the MLL gene in adult T-lymphoblastic leukemia

Long distance polymerase chain reaction of ascites lymphoma cells aids diagnosis establishment of abdominal Burkitt's lymphoma and Burkitt-like lymphoma.

Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL

Long-term relapse-free survival in a phase 2 study of blinatumomab for the treatment of patients with minimal residual disease in B-lineage acute lymphoblastic leukemia

Loss-of-function but not dominant-negative intragenic IKZF1 deletions are associated with an adverse prognosis in adult BCR-ABL-negative acute lymphoblastic leukemia

Low ERG and BAALC expression identifies a new subgroup of adult acute T-lymphoblastic leukemia with a highly favorable outcome

MLL: exploring the methylome

Melting point assay for the JAK2 V617F mutation, comparison with amplification refractory mutation system (ARMS) in diagnostic samples, and implications for daily routine.

Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts

Molecular analysis of the t(2;8)/MYC-IGK translocation in high-grade lymphoma/leukemia by long-distance inverse PCR.

Molecular characterization and clinical course of MLL-ACTN4 rearrangement in therapy-related hematologic malignancies

Molecular heterogeneity of sporadic adult Burkitt-type leukemia/lymphoma as revealed by PCR and cytogenetics: correlation with morphology, immunology and clinical features.

Molecular monitoring in NUP214-ABL-positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy.

Molekulargenetik

Molekulargenetik bei Leukämien

Monitoring minimal residual disease by quantification of genomic chromosomal breakpoint sequences in acute leukemias with MLL aberrations.

NUP214-ABL1 in adult T-ALL: the GMALL study group experience.

New insights to the MLL recombinome of acute leukemias

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

Oncogenic retroviruses in animals and humans.

Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia

PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia

Patients' age and BCR-ABL frequency in adult B-precursor ALL: a retrospective analysis from the GMALL study group

Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia

Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia

Randomized comparison of prophylactic and minimal residual disease-triggered imatinib after allogeneic stem cell transplantation for BCR-ABL1-positive acute lymphoblastic leukemia

Rapid and sensitive detection of calreticulin type 1 and 2 mutations by real-time quantitative PCR.

Skewed expression of natural-killer (NK)-associated antigens on lymphoproliferations of large granular lymphocytes (LGL).

Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia.

Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival.

The MLL recombinome of acute leukemias

The MLL recombinome of acute leukemias in 2013.

The MLL recombinome of acute leukemias in 2017.

The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group

Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group.

Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia.