List of works - Mario Milco D'Elios

A T Cell Suppressive Circuitry Mediated by CD39 and Regulated by ShcC/Rai Is Induced in Astrocytes by Encephalitogenic T Cells

scientific article published on 10 May 2019

Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders

scientific article published on 01 July 1993

An approach to differential diagnosis of antiphospholipid antibody syndrome and related conditions

scientific article published on 14 October 2014

An update on human Th1 and Th2 cells.

scientific article published on May 1997

Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling

scientific article

Arterial occlusion mimicking vasculitis in a patient with incontinentia pigmenti

scientific article

Autoantibodies against β1-Adrenergic Receptors: Response to Cardiac Resynchronization Therapy and Renal Function

scientific article published on 26 October 2015

Autoimmune diseases: Role of steroid hormones

scientific article published on 16 March 2019

Behçet's syndrome pathophysiology and potential therapeutic targets

scientific article published on 12 January 2014

Behçet's syndrome patients exhibit specific microbiome signature

scientific article

Bioethics under the Tuscan sun

scientific article published on 01 March 2005

Borrelia burgdorferiNapA-driven Th17 cell inflammation in lyme arthritis

scientific article published on 01 November 2008

Bringing new players into the field: onco-pharmacovigilance in the era of cardio-oncology

scientific article published on 22 January 2012

CD25 deficiency: A new conformational mutation prevents the receptor expression on cell surface

scientific article published on 08 February 2019

CD8 T-cell clones producing interleukin-5 and interferon-gamma in bronchial mucosa of patients with asthma induced by toluene diisocyanate

scientific article published on 01 October 1994

Cardiovascular oncology: a new discipline inside internal medicine?

scientific article published on 19 March 2014

Cerebrospinal fluid T-regulatory cells recognize Borrelia burgdorferi NAPA in chronic Lyme borreliosis.

scientific article

Characterization of H+,K+-ATPase T cell epitopes in human autoimmune gastritis.

scientific article published in February 2003

Characterization of tumor antigen peptide-specific T cells isolated from the neoplastic tissue of patients with gastric adenocarcinoma.

scientific article published on 25 March 2009

Contraception in autoimmune diseases

scientific article published on 11 May 2019

Correction: The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis.

scientific article published in November 2016

Corrigendum: Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway.

scientific article published on 16 February 2018

Cytolytic T cells with Th1-like cytokine profile predominate in retroorbital lymphocytic infiltrates of Graves' ophthalmopathy

scientific article published on 01 November 1993

Cytotoxic Th1 and Th17 cells infiltrate the intestinal mucosa of Behcet patients and exhibit high levels of TNF-α in early phases of the disease

scientific article published on December 2016

Decline in Total Serum IgE and Soluble CD30 in the Context of Soil-Transmitted Helminth Decline in Bolivia

scientific article published on 01 April 2020

Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects

scientific article published on 7 April 2005

Defective recruitment and activation of ZAP-70 in common variable immunodeficiency patients with T cell defects

scientific article published on 01 September 2000

Different cytokine profile and antigen-specificity repertoire inHelicobacter pylori-specific T cell clones from the antrum of chronic gastritis patients with or without peptic ulcer

scientific article published on 01 July 1997

Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections.

scientific article published in January 1997

Digital ulcers secondary to Sneddon's syndrome successfully treated with Bosentan: not only useful in Systemic Sclerosis

scientific article

Expression of the T-cell-specific tyrosine kinase Lck in normal B-1 cells and in chronic lymphocytic leukemia B cells

scientific article published on 01 May 1998

Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells.

scientific article published on August 2016

Frequent loss of heterozygosity without loss of genetic material in acute myeloid leukemia with a normal karyotype

article

Gastric Autoimmunity

H+,K+-ATPase (proton pump) is the target autoantigen of Th1-type cytotoxic T cells in autoimmune gastritis

scientific article published on 01 February 2001

Helicobacter pylori and gastric autoimmunity.

scientific article

Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphoma.

scientific article

Helicobacter pylori cagPathogenicity Island Is Associated with Reduced Expression of Interleukin-4 (IL-4) mRNA and Modulation of the IL-4δ2 mRNA Isoform in Human Gastric Mucosa ⬇️

scientific article published on November 1, 2003

Helicobacter pylori management in primary care

scientific article published on 22 September 2011

Helicobacter pylori secreted peptidyl prolyl cis, trans-isomerase drives Th17 inflammation in gastric adenocarcinoma

scientific article published on 05 October 2012

Helicobacter pylori, T cells and cytokines: the "dangerous liaisons".

scientific article

Helicobacter pylori, asthma and allergy.

scientific article published on 10 February 2009

Helicobacter pylori: usefulness of an empirical fourth-line rifabutin-based regimen

scientific article published on 01 August 2012

Human Th1 and Th2 T-cell clones are equally susceptible to infection and immortalization by human T-lymphotropic virus type I.

scientific article published in October 1998

IFN-gamma-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection

scientific article

Immortalization with herpesvirus saimiri modulates the cytokine secretion profile of established Th1 and Th2 human T cell clones.

scientific article published in November 1993

Immune mechanisms in the pathogenesis of inflammatory gastrointestinal disorders.

scientific article published on November 1996

Immunity, inflammation, and vaccines for Helicobacter pylori

scientific article

Immunosuppression of TH2 responses in Trichinella spiralis infection by Helicobacter pylori neutrophil-activating protein

article

Impaired T-cell regulation of B-cell growth in Helicobacter pylori–related gastric low-grade MALT lymphoma

scientific article published on 01 November 1999

Impaired TH2 response in patients with Vav1-deficient common variable immunodeficiency with T-cell defects

scientific article published on 16 July 2010

In vivo CD30 expression in human diseases with predominant activation of Th2-like T cells

scientific article published on 01 May 1997

In vivo relevance of CD30 in atopic dermatitis

scientific article published on 01 November 1997

Interleukin-17/Interleukin-21 and Interferon-γ producing T cells specific for β2 Glycoprotein I in atherosclerosis inflammation of systemic lupus erythematosus patients with antiphospholipid syndrome

scientific article published on 14 March 2019

Intra-tumoral IFN-γ-producing Th22 cells correlate with TNM staging and the worst outcomes in pancreatic cancer.

scientific article published on 20 November 2015

LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy

scientific article published on 21 March 2019

Long-term efficacy and safety of anakinra in a patient with Behçet's disease and concomitant tuberculosis infection.

scientific article published on 23 June 2016

Lupus Anticoagulant and Monocyte Procoagulant Activity in Polyabortive Women

scientific article published on 01 January 1993

Management ofHelicobacter pyloriinfection

scientific article published on 01 August 2010

Molecular mimicry between Helicobacter pylori antigens and H+, K+ --adenosine triphosphatase in human gastric autoimmunity

scientific article published in October 2003

Moraxella Catarrhalis-Specific Th1 Cells in Bal Fluids of Chronic Obstructive Pulmonary Disease Patients

scientific article published on 01 October 2009

Multiorgan infiltration by CD8+ T cells and 1p;16p translocation in a patient with hypogammaglobulinemia and a reduced number of B cells.

scientific article published on 26 January 2012

Multiple sclerosis: the role of cytokines in pathogenesis and in therapies

retracted scientific article

Neonatal bacillus Calmette-Guérin vaccination induces adult-like IFN-gamma production by CD4+ T lymphocytes.

scientific article published in May 2001

New frontiers in cell-based immunotherapy of cancer.

scientific article published on May 2009

Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling.

scientific article published on 28 October 2004

Novel M. tuberculosis specific IL-2 ELISpot assay discriminates adult patients with active or latent tuberculosis.

scientific article published in June 2018

Oral vitamin B12: Efficacy and safety data in 31 patients with pernicious anemia and food-cobalamin malabsorption

scientific article

Pathogenesis and potential therapeutic targets in systemic lupus erythematosus: from bench to bedside

scientific article

Peripheral ENO1-specific T cells mirror the intratumoral immune response and their presence is a potential prognostic factor for pancreatic adenocarcinoma.

scientific article published on 16 May 2016

Phenotype and cytokine profile of Schistosoma mansoni specific T cell lines and clones derived from schistosomiasis patients with distinct clinical forms.

scientific article published on June 1999

Placental bed research: II. Functional and immunological investigations of the placental bed

scientific article published on 06 July 2019

Polarization of PPD-specific T-cell response of patients with tuberculosis from Th0 to Th1 profile after successful antimycobacterial therapy or in vitro conditioning with interferon-alpha or interleukin-12.

scientific article published in February 2001

Polyclonal B cell activation induced by herpesvirus saimiri-transformed human CD4+ T cell clones. Role for membrane TNF-alpha/TNF-alpha receptors and CD2/CD58 interactions.

scientific article published on December 1994

Potential role of M. tuberculosis specific IFN-γ and IL-2 ELISPOT assays in discriminating children with active or latent tuberculosis

scientific article

Predominant Th1 cell infiltration in acute rejection episodes of human kidney grafts

scientific article published on 01 June 1997

Prevalence of allergy and asthma in a rural community of children and adults in Bolivian Chaco

scientific article published on 07 August 2019

Prevention of miscarriage in antiphospholipid syndrome

scientific article published on January 1, 1992

Pulmonary fibrosis and lymphocytic alveolitis associated with triple antiphospholipid antibody positivity: a diagnostic puzzle.

scientific article published in September 2012

Renal dysfunction and increased risk of cardiotoxicity with trastuzumab therapy: a new challenge in cardio-oncology

scientific article published on 02 September 2012

Reply to letter by Nardelli and Schell commenting on the pathogenesis of lyme arthritis

scientific article published on 01 July 2009

Role of Mycobacterium avium lysate INF-γ, IL-17, and IL-2 ELISPOT assays in diagnosing nontuberculous mycobacteria lymphadenitis in children

scientific article published on 05 March 2019

Role of TH1/TH2 cytokines in HIV infection.

scientific article published on August 1994

Role of immune response in Yersinia pestis infection.

scientific article published on 14 September 2011

Second European multi-disciplinary conference of national strategies for Chlamydia trach. and human papillomavirus NSCP conf. in Berlin, 2013 enhanced detection, management and surveillance of sexually transmitted infections in Europe are essential!

scientific article published in October 2013

Systemic lupus erythematosus: immunopathogenesis and novel therapeutic targets.

scientific article

T cells and adoptive immunotherapy: recent developments and future prospects in gastrointestinal oncology.

scientific article published on 3 November 2011

T cells in gastric cancer: friends or foes

scientific article published on 31 May 2012

T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease

scientific article published on 01 January 1997

T helper type 1 lymphocytes drive inflammation in human atherosclerotic lesions

scientific article

T-cell clones in human trichinellosis: Evidence for a mixed Th1/Th2 response.

scientific article

T-cell response to bacterial agents

scientific article

Targeting IL-23 in human diseases.

scientific article published on July 2010

Th1 and Th2 T-helper cells exert opposite regulatory effects on procoagulant activity and tissue factor production by human monocytes.

scientific article published on July 1995

Th1/Th2 balance in human disease

scientific article published on 01 August 1998

The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis.

scientific article published on 10 June 2016

The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells

scientific article published on 11 January 2017

The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms.

scientific article published on December 2003

The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development

scientific article published on 23 January 2013

The adenylate cyclase toxin of Bacillus anthracis is a potent promoter of TH17 cell development

scientific article published on 09 February 2011

The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling

scientific article

The glycopeptide CSF114(Glc) detects serum antibodies in multiple sclerosis

scientific article published on 01 October 2005

The immune modulating activity of the Helicobacter pylori HP-NAP: Friend or foe?

scientific article published on 08 October 2009

The lipoprotein HP1454 of Helicobacter pylori regulates T-cell response by shaping T-cell receptor signalling

scientific article published on 31 January 2019

The neutrophil-activating protein ofHelicobacter pyloridown-modulates Th2 inflammation in ovalbumin-induced allergic asthma

scientific article published on 15 August 2008

The placental bed vascular pathology revisited: a risk indicator for cardiovascular disease

scientific article published on 26 November 2017

The story so far: Helicobacter pylori and gastric autoimmunity.

scientific article

Therapy for Non-Muscle Invasive Bladder Cancer: HP-NAP

scientific article published on 01 April 2012

Thrombosis in vasculitis: from pathogenesis to treatment

scientific article

To treat or not to treatHelicobacter pylorito benefit asthma patients

scientific article published on 01 April 2010

TpF1 from Treponema pallidum activates inflammasome and promotes the development of regulatory T cells.

scientific article published on 27 June 2011

Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway

scientific article

Tumor-associated macrophages as major source of APRIL in gastric MALT lymphoma

scientific article published on 28 April 2011

USF1 defect drives p53 degradation during Helicobacter pylori infection and accelerates gastric carcinogenesis

scientific article published on 10 December 2019

Uncoupling of T-Cell Antigen Receptor and Downstream Protein Tyrosine Kinases in Common Variable Immunodeficiency

scientific article published on 01 July 1997

Usefulness of (13)C-urea breath test in the diagnosis of gastric helicobacter pylori infection.

scientific article published in January 2000

VacA and HP-NAP, Ying and Yang of Helicobacter pylori-associated gastric inflammation.

scientific article published on 21 February 2007

Vav1 Haploinsufficiency in a Common Variable Immunodeficiency Patient with Defective T-Cell Function

scientific article published on 01 July 2012

What is recent in pancreatic cancer immunotherapy?

scientific article published on 26 December 2012

[Atherosclerosis, an historical approach]

scientific article published on 01 January 2007

[Helicobacter pylori, the story so far].

scientific article published in January 2007

p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes.

scientific article

p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape

scientific article published on 28 February 2019

β2 Glycoprotein I Recognition Drives Th1 Inflammation in Atherosclerotic Plaques of Patients with Primary Antiphospholipid Syndrome

scientific article published on 13 February 2017

List of works by Mario Milco D'Elios

A T Cell Suppressive Circuitry Mediated by CD39 and Regulated by ShcC/Rai Is Induced in Astrocytes by Encephalitogenic T Cells

Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders

An approach to differential diagnosis of antiphospholipid antibody syndrome and related conditions

An update on human Th1 and Th2 cells.

Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling

Arterial occlusion mimicking vasculitis in a patient with incontinentia pigmenti

Autoantibodies against β1-Adrenergic Receptors: Response to Cardiac Resynchronization Therapy and Renal Function

Autoimmune diseases: Role of steroid hormones

Behçet's syndrome pathophysiology and potential therapeutic targets

Behçet's syndrome patients exhibit specific microbiome signature

Bioethics under the Tuscan sun

Borrelia burgdorferiNapA-driven Th17 cell inflammation in lyme arthritis

Bringing new players into the field: onco-pharmacovigilance in the era of cardio-oncology

CD25 deficiency: A new conformational mutation prevents the receptor expression on cell surface

CD8 T-cell clones producing interleukin-5 and interferon-gamma in bronchial mucosa of patients with asthma induced by toluene diisocyanate

Cardiovascular oncology: a new discipline inside internal medicine?

Cerebrospinal fluid T-regulatory cells recognize Borrelia burgdorferi NAPA in chronic Lyme borreliosis.

Characterization of H+,K+-ATPase T cell epitopes in human autoimmune gastritis.

Characterization of tumor antigen peptide-specific T cells isolated from the neoplastic tissue of patients with gastric adenocarcinoma.

Contraception in autoimmune diseases

Correction: The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis.

Corrigendum: Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway.

Cytolytic T cells with Th1-like cytokine profile predominate in retroorbital lymphocytic infiltrates of Graves' ophthalmopathy

Cytotoxic Th1 and Th17 cells infiltrate the intestinal mucosa of Behcet patients and exhibit high levels of TNF-α in early phases of the disease

Decline in Total Serum IgE and Soluble CD30 in the Context of Soil-Transmitted Helminth Decline in Bolivia

Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects

Defective recruitment and activation of ZAP-70 in common variable immunodeficiency patients with T cell defects

Different cytokine profile and antigen-specificity repertoire inHelicobacter pylori-specific T cell clones from the antrum of chronic gastritis patients with or without peptic ulcer

Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections.

Digital ulcers secondary to Sneddon's syndrome successfully treated with Bosentan: not only useful in Systemic Sclerosis

Expression of the T-cell-specific tyrosine kinase Lck in normal B-1 cells and in chronic lymphocytic leukemia B cells

Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells.

Frequent loss of heterozygosity without loss of genetic material in acute myeloid leukemia with a normal karyotype

Gastric Autoimmunity

H+,K+-ATPase (proton pump) is the target autoantigen of Th1-type cytotoxic T cells in autoimmune gastritis

Helicobacter pylori and gastric autoimmunity.

Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphoma.

Helicobacter pylori cagPathogenicity Island Is Associated with Reduced Expression of Interleukin-4 (IL-4) mRNA and Modulation of the IL-4δ2 mRNA Isoform in Human Gastric Mucosa ⬇️

Helicobacter pylori management in primary care

Helicobacter pylori secreted peptidyl prolyl cis, trans-isomerase drives Th17 inflammation in gastric adenocarcinoma

Helicobacter pylori, T cells and cytokines: the "dangerous liaisons".

Helicobacter pylori, asthma and allergy.

Helicobacter pylori: usefulness of an empirical fourth-line rifabutin-based regimen

Human Th1 and Th2 T-cell clones are equally susceptible to infection and immortalization by human T-lymphotropic virus type I.

IFN-gamma-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection

Immortalization with herpesvirus saimiri modulates the cytokine secretion profile of established Th1 and Th2 human T cell clones.

Immune mechanisms in the pathogenesis of inflammatory gastrointestinal disorders.

Immunity, inflammation, and vaccines for Helicobacter pylori

Immunosuppression of TH2 responses in Trichinella spiralis infection by Helicobacter pylori neutrophil-activating protein

Impaired T-cell regulation of B-cell growth in Helicobacter pylori–related gastric low-grade MALT lymphoma

Impaired TH2 response in patients with Vav1-deficient common variable immunodeficiency with T-cell defects

In vivo CD30 expression in human diseases with predominant activation of Th2-like T cells

In vivo relevance of CD30 in atopic dermatitis

Interleukin-17/Interleukin-21 and Interferon-γ producing T cells specific for β2 Glycoprotein I in atherosclerosis inflammation of systemic lupus erythematosus patients with antiphospholipid syndrome

Intra-tumoral IFN-γ-producing Th22 cells correlate with TNM staging and the worst outcomes in pancreatic cancer.

LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy

Long-term efficacy and safety of anakinra in a patient with Behçet's disease and concomitant tuberculosis infection.

Lupus Anticoagulant and Monocyte Procoagulant Activity in Polyabortive Women

Management ofHelicobacter pyloriinfection

Molecular mimicry between Helicobacter pylori antigens and H+, K+ --adenosine triphosphatase in human gastric autoimmunity

Moraxella Catarrhalis-Specific Th1 Cells in Bal Fluids of Chronic Obstructive Pulmonary Disease Patients

Multiorgan infiltration by CD8+ T cells and 1p;16p translocation in a patient with hypogammaglobulinemia and a reduced number of B cells.

Multiple sclerosis: the role of cytokines in pathogenesis and in therapies

Neonatal bacillus Calmette-Guérin vaccination induces adult-like IFN-gamma production by CD4+ T lymphocytes.

New frontiers in cell-based immunotherapy of cancer.

Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling.

Novel M. tuberculosis specific IL-2 ELISpot assay discriminates adult patients with active or latent tuberculosis.

Oral vitamin B12: Efficacy and safety data in 31 patients with pernicious anemia and food-cobalamin malabsorption

Pathogenesis and potential therapeutic targets in systemic lupus erythematosus: from bench to bedside

Peripheral ENO1-specific T cells mirror the intratumoral immune response and their presence is a potential prognostic factor for pancreatic adenocarcinoma.

Phenotype and cytokine profile of Schistosoma mansoni specific T cell lines and clones derived from schistosomiasis patients with distinct clinical forms.

Placental bed research: II. Functional and immunological investigations of the placental bed

Polarization of PPD-specific T-cell response of patients with tuberculosis from Th0 to Th1 profile after successful antimycobacterial therapy or in vitro conditioning with interferon-alpha or interleukin-12.

Polyclonal B cell activation induced by herpesvirus saimiri-transformed human CD4+ T cell clones. Role for membrane TNF-alpha/TNF-alpha receptors and CD2/CD58 interactions.

Potential role of M. tuberculosis specific IFN-γ and IL-2 ELISPOT assays in discriminating children with active or latent tuberculosis

Predominant Th1 cell infiltration in acute rejection episodes of human kidney grafts

Prevalence of allergy and asthma in a rural community of children and adults in Bolivian Chaco

Prevention of miscarriage in antiphospholipid syndrome

Pulmonary fibrosis and lymphocytic alveolitis associated with triple antiphospholipid antibody positivity: a diagnostic puzzle.