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List of works by Paola Cappello

A bioluminescent mouse model of proliferation to highlight early stages of pancreatic cancer: A suitable tool for preclinical studies.

scientific article published on 15 December 2015

AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer

scientific article published on 07 February 2019

Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis

scientific article published on 13 January 2017

Anti-α-enolase antibody limits the invasion of myeloid-derived suppressor cells and attenuates their restraining effector T cell response

scientific article

Autoantibodies to Ezrin are an early sign of pancreatic cancer in humans and in genetically engineered mouse models

scientific article published on 06 September 2013

Autoantibody signature in human ductal pancreatic adenocarcinoma.

scientific article published on 8 September 2007

CCL16 activates an angiogenic program in vascular endothelial cells.

scientific article published on 4 September 2003

CCL16/LEC powerfully triggers effector and antigen-presenting functions of macrophages and enhances T cell cytotoxicity

scientific article published on 2 October 2003

Chimeric rat/human HER2 efficiently circumvents HER2 tolerance in cancer patients

scientific article published on 25 March 2014

Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM-1 expression

scientific article published on 06 March 2013

Circulating Autoantibodies to Phosphorylated α-Enolase are a Hallmark of Pancreatic Cancer

scientific article published on 10 June 2010

Class II transactivator-induced MHC class II expression in pancreatic cancer cells leads to tumor rejection and a specific antitumor memory response.

scientific article

Death receptor ligands in tumors

scientific article

Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype

scientific article published on 13 November 2017

Early expression of the fractalkine receptor CX3CR1 in pancreatic carcinogenesis

scientific article published on October 2013

Effects of liver ischemia-reperfusion injury on respiratory mechanics and driving pressure during orthotopic liver transplantation

scientific article published on 30 October 2018

Endogenous glutamine decrease is associated with pancreatic cancer progression.

scientific article published on 24 August 2017

Expression of IFNγR2 mutated in a dileucine internalization motif reinstates IFNγ signaling and apoptosis in human T lymphocytes

scientific article published on 13 August 2010

Extracorporeal CO2 Removal May Improve Renal Function of Patients with Acute Respiratory Distress Syndrome and Acute Kidney Injury: An Open-Label, Interventional Clinical Trial

scientific article published on 01 September 2018

FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis

scientific article published on 23 October 2017

Human dendritic cells differentiated in hypoxia down-modulate antigen uptake and change their chemokine expression profile

scientific article published on 25 August 2008

Humoral immune responses toward tumor-derived antigens in previously untreated patients with chronic lymphocytic leukemia

scientific article

Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo

article

IFN-gamma inhibits the proliferation of allergen-activated T lymphocytes from atopic, asthmatic patients by inducing Fas/FasL-mediated apoptosis

scientific article

Immunological mechanisms elicited at the tumour site by lymphocyte activation gene-3 (LAG-3) versus IL-12: sharing a common Th1 anti-tumour immune pathway

scientific article

In pancreatic cancer, chemotherapy increases antitumor responses to tumor-associated antigens and potentiates DNA vaccination

scientific article published on 01 October 2020

Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression

scientific article

Metabolome of Pancreatic Juice Delineates Distinct Clinical Profiles of Pancreatic Cancer and Reveals a Link between Glucose Metabolism and PD-1+ Cells

scientific article published on 04 February 2020

Molecular and genetic bases of pancreatic cancer.

scientific article published on June 2012

Neuromuscular Blocking Agent Cisatracurium Attenuates Lung Injury by Inhibition of Nicotinic Acetylcholine Receptor-α1.

scientific article

Next Generation Immunotherapy for Pancreatic Cancer: DNA Vaccination is Seeking New Combo Partners

scientific article published on 16 February 2018

Peripheral ENO1-specific T cells mirror the intratumoral immune response and their presence is a potential prognostic factor for pancreatic adenocarcinoma

scientific article published on 16 May 2016

Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth.

scientific article published on 18 January 2018

Prenatal differentiation of mouse vomeronasal neurones

scientific article published on 01 January 1998

Proliferation and apoptosis in the mouse vomeronasal organ during ontogeny

scientific article published on 01 April 1999

Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1

scientific article published on 15 February 2019

Regulation of Langerhans cell functions in a hypoxic environment.

scientific article published on 10 March 2016

Role of Nek2 on centrosome duplication and aneuploidy in breast cancer cells.

scientific article published on 27 May 2013

Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma

scientific article published on 27 September 2005

Soluble stroma-related biomarkers of pancreatic cancer.

scientific article

Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma.

scientific article published on 11 September 2015

Strigolactone Analogs Are Promising Antiviral Agents for the Treatment of Human Cytomegalovirus Infection

scientific article published on 10 May 2020

Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer

scientific article published on 10 November 2018

Sulfated K5 Escherichia coli polysaccharide derivatives as wide-range inhibitors of genital types of human papillomavirus.

scientific article published on 4 February 2008

Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway

scientific article

Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells

scientific article published on May 2015

Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest

scientific article published on 30 December 2015

The advanced glycation end-product Nϵ -carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention.

scientific article published on 13 March 2018

The balance between IL-17 and IL-22 produced by liver-infiltrating T-helper cells critically controls NASH development in mice

scientific article published on 11 November 2015

The hypoxic environment reprograms the cytokine/chemokine expression profile of human mature dendritic cells

scientific article

The interferon-inducible IFI16 gene inhibits tube morphogenesis and proliferation of primary, but not HPV16 E6/E7-immortalized human endothelial cells

scientific article (publication date: 15 February 2004)

The interferon-inducible gene IFI16 secretome of endothelial cells drives the early steps of the inflammatory response

scientific article

The proapoptotic activity of the Interferon-inducible gene IFI16 provides new insights into its etiopathogenetic role in autoimmunity

scientific article

Three are better than one: plasminogen receptors as cancer theranostic targets.

scientific article published on 17 April 2013

Transcriptome of Hypoxic Immature Dendritic Cells: Modulation of Chemokine/Receptor Expression

scientific article published on 01 February 2008

Tumor rejection and immune memory elicited by locally released LEC chemokine are associated with an impressive recruitment of APCs, lymphocytes, and granulocytes

scientific article published on 01 March 2000

Vaccination with ENO1 DNA prolongs survival of genetically engineered mice with pancreatic cancer.

scientific article published on 16 January 2013

Ventilatory Management During Normothermic Ex Vivo Lung Perfusion: Effects on Clinical Outcomes.

scientific article published in October 2015

α-Enolase: a promising therapeutic and diagnostic tumor target.

scientific article published on 24 February 2011

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