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List of works by Ayumu Nakashima

15-Deoxy-Delta12,14-prostaglandin J2 inhibits angiotensin II-induced fibronectin expression via hepatocyte growth factor induction in human peritoneal mesothelial cells.

scientific article published in February 2010

A novel noninvasive and simple method for assessment of endothelial function: enclosed zone flow-mediated vasodilation (ezFMD) using an oscillation amplitude measurement.

scientific article published on 6 June 2013

Association of nodular hyperplasia with resistance to cinacalcet therapy for secondary hyperparathyroidism in hemodialysis patients.

scientific article published on December 2010

Autologous bone-marrow mesenchymal stem cell implantation and endothelial function in a rabbit ischemic limb model.

scientific article

Borderline ankle-brachial index value of 0.91-0.99 is associated with endothelial dysfunction

scientific article published on 10 May 2014

Brachial artery diameter as a marker for cardiovascular risk assessment: FMD-J study.

scientific article

C-C chemokine receptor 2 expression by circulating monocytes influences atherosclerosis in patients on chronic hemodialysis

scientific article published on 01 June 2009

Chronic kidney disease is associated with vascular smooth muscle dysfunction but not with endothelial dysfunction.

scientific article

Circulating level of pigment epithelium-derived factor is associated with vascular function and structure: A cross-sectional study

scientific article published on 3 October 2016

Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension

scientific article published on 12 January 2018

Combination of Flow-Mediated Vasodilation and Nitroglycerine-Induced Vasodilation Is More Effective for Prediction of Cardiovascular Events.

scientific article published on 14 March 2016

Critical role of exogenous nitric oxide in ROCK activity in vascular smooth muscle cells

scientific article

Dec1 and CLOCK Regulate Na+/K+-ATPase β1 Subunit Expression and Blood Pressure

scientific article published on 01 September 2018

Decreased frequency and duration of tooth brushing is a risk factor for endothelial dysfunction.

scientific article

Deficiency of the basic helix-loop-helix transcription factor DEC1 prevents obesity induced by a high-fat diet in mice

scientific article published on 03 July 2018

Deubiquitinase inhibitor PR-619 reduces Smad4 expression and suppresses renal fibrosis in mice with unilateral ureteral obstruction

scientific article published in PLoS ONE

Diagnostic Criteria of Flow-Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin-Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery

scientific article published on 08 January 2020

Different circadian expression of major matrix-related genes in various types of cartilage: modulation by light-dark conditions.

scientific article published on 11 August 2013

Different risk factors for the maximum and the mean carotid intima-media thickness in hemodialysis patients

scientific article published on 01 November 2003

Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study

scientific article published on 15 July 2019

Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism.

scientific article published on 26 January 2015

Effect of circulating soluble receptor for advanced glycation end products (sRAGE) and the proinflammatory RAGE ligand (EN-RAGE, S100A12) on mortality in hemodialysis patients

scientific article

Effects of fasting and re-feeding on the expression of Dec1, Per1, and other clock-related genes.

scientific article published on 27 July 2006

Effects of vitamin K2 in hemodialysis patients with low serum parathyroid hormone levels

scientific article published in March 2004

Efficacy of add-on therapy of aliskiren to an angiotensin II receptor blocker on renal outcomes in advanced-stage chronic kidney disease: a prospective, randomized, open-label study

scientific article published on 22 October 2014

Endogenous estrogen may prevent bone loss in postmenopausal hemodialysis patients throughout life.

scientific article published on 22 July 2010

Endothelial Dysfunction, Increased Arterial Stiffness, and Cardiovascular Risk Prediction in Patients With Coronary Artery Disease: FMD-J (Flow-Mediated Dilation Japan) Study A

scientific article published on 12 July 2018

Endothelial Function Assessed by Automatic Measurement of Enclosed Zone Flow-Mediated Vasodilation Using an Oscillometric Method Is an Independent Predictor of Cardiovascular Events.

scientific article published on 21 December 2016

Endothelial Function Is Impaired in Patients Receiving Antihypertensive Drug Treatment Regardless of Blood Pressure Level: FMD-J Study (Flow-Mediated Dilation Japan).

scientific article published on 14 August 2017

Endothelial dysfunction and abnormal vascular structure are simultaneously present in patients with heart failure with preserved ejection fraction

scientific article published on 05 January 2017

Endothelial dysfunction, abnormal vascular structure and lower urinary tract symptoms in men and women

scientific article published on 01 June 2018

Endothelial function is impaired in relation to alcohol intake even in the case of light alcohol consumption in Asian men; Flow-mediated Dilation Japan (FMD-J) Study.

scientific article published on 21 December 2016

Exogenous nitric oxide inhibits Rho-associated kinase activity in patients with angina pectoris: a randomized controlled trial.

scientific article published on 05 March 2015

Expression of age-related factors during the development of renal damage in patients with IgA nephropathy.

scientific article

Flow-mediated vasodilation and anatomical variation of the brachial artery (double brachial artery) in healthy subjects and patients with cardiovascular disease

scientific article published on 7 December 2012

Hepatitis B virus infection in hemodialysis patients in Japan: Prevalence, incidence and occult hepatitis B virus infection

scientific article published on 19 January 2015

High glucose promotes TGF-β1 production by inducing FOS expression in human peritoneal mesothelial cells

scientific article published on 28 May 2015

High-normal albuminuria and incident chronic kidney disease in a male nondiabetic population.

scientific article published on 26 December 2017

High-normal albuminuria is strongly associated with incident chronic kidney disease in a nondiabetic population with normal range of albuminuria and normal kidney function

scientific article published on 19 February 2020

Hyperuricemia is independently associated with endothelial dysfunction in postmenopausal women but not in premenopausal women

scientific article

Increased arterial stiffness and cardiovascular risk prediction in controlled hypertensive patients with coronary artery disease: post hoc analysis of FMD-J (Flow-mediated Dilation Japan) Study A

scientific article published on 09 March 2020

Increasing Risk of Osteoporotic Fracture Is Associated With Vascular Dysfunction and Abnormal Vascular Structure in Both Men and Women

scientific article published on 23 February 2017

Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression

scientific article published on 7 October 2015

Inhibition of H3K9 methyltransferase G9a ameliorates methylglyoxal-induced peritoneal fibrosis

scientific article

Inhibition of SET Domain-Containing Lysine Methyltransferase 7/9 Ameliorates Renal Fibrosis

scientific article

Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16INK4a

scientific article published on 01 August 2019

Inhibition of the H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis.

scientific article

Interrelationships Among Flow-Mediated Vasodilation, Nitroglycerine-Induced Vasodilation, Baseline Brachial Artery Diameter, Hyperemic Shear Stress, and Cardiovascular Risk Factors.

scientific article published on 29 December 2017

Intima-media thickness of brachial artery, vascular function, and cardiovascular risk factors

scientific article published on 12 July 2012

Ionizing Irradiation Induces Vascular Damage in the Aorta of Wild-Type Mice

scientific article published on 18 October 2020

Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice

scientific article

Liver X receptors (LXRalpha and LXRbeta) are potent regulators for hepatic Dec1 expression.

scientific article

Low serum testosterone is associated with atherosclerosis in postmenopausal women undergoing hemodialysis.

scientific article published on 26 July 2013

Mesenchymal Stem Cell-Based Therapy Improves Lower Limb Movement After Spinal Cord Ischemia in Rats

scientific article published on 11 January 2018

Mizoribine ameliorates renal injury and hypertension along with the attenuation of renal caspase-1 expression in aldosterone-salt-treated rats.

scientific article

Mizoribine suppresses the progression of experimental peritoneal fibrosis in a rat model.

scientific article published on 23 April 2009

Morning blood pressure is useful for detection of left ventricular hypertrophy in hemodialysis patients

scientific article published on 12 May 2012

N-terminal pro brain natriuretic peptide as a cardiac biomarker in Japanese hemodialysis patients.

scientific article published on 20 February 2018

Na+-Cl- cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats

scientific article published on 04 April 2018

New assessment of endothelial function measured by short time flow-mediated vasodilation: Comparison with conventional flow-mediated vasodilation measurement

scientific article published on 04 May 2018

Nitroglycerine-induced vasodilation for assessment of vascular function: a comparison with flow-mediated vasodilation.

scientific article published on 21 March 2013

Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease

scientific article published on 15 June 2016

Non-Invasive Central Venous Pressure Measurement Using Enclosed-Zone Central Venous Pressure (ezCVPTM)

scientific article published on 15 May 2020

Optimal Target Level of Low-density Lipoprotein Cholesterol for Vascular Function in Statin Naïve Individuals.

scientific article published on 21 August 2017

Osteoprotegerin and bone mineral density in hemodialysis patients.

scientific article published on 7 April 2006

Performance of polysulfone membrane dialyzers and dialysate flow pattern

scientific article published on 01 September 2006

Plasma osteoprotegerin, arterial stiffness, and mortality in normoalbuminemic Japanese hemodialysis patients

scientific article published on 02 September 2010

Poor oral health, that is, decreased frequency of tooth brushing, is associated with endothelial dysfunction

scientific article published on 05 February 2014

Postprandial metabolic response to a fat- and carbohydrate-rich meal in patients with chronic kidney disease

scientific article published on 23 November 2010

Prevalence and clinical implications of testosterone deficiency in men with end-stage renal disease.

scientific article published on 11 July 2010

Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury

scientific article published on 01 July 2007

Protein-energy wasting modifies the association of ghrelin with inflammation, leptin, and mortality in hemodialysis patients

scientific article published in April 2011

Radial Bone Mineral Density in Hemodialysis Patients with Adynamic Bone Disease ⬇️

scientific article published on 01 March 2003

Ratio of serum levels of AGEs to soluble form of RAGE is a predictor of endothelial function

scientific article published on 21 October 2014

Reactive hyperemia-peripheral arterial tonometry is useful for assessment of not only endothelial function but also stenosis of the digital artery.

scientific article published in June 2018

Reduction in blood pressure improves impaired nitroglycerine-induced vasodilation in patients with essential hypertension.

scientific article published on 3 September 2015

Relation of the Bilateral Earlobe Crease to Endothelial Dysfunction.

scientific article published on 29 March 2017

Relationship between flow-mediated vasodilation and cardiovascular risk factors in a large community-based study.

scientific article published on 23 October 2013

Relationship between home blood pressure and vascular function in patients receiving antihypertensive drug treatment

scientific article published on 07 March 2019

Relationship between nitroglycerine-induced vasodilation and clinical severity of peripheral artery disease

scientific article published on 26 April 2014

Relationship between serum triglyceride levels and endothelial function in a large community-based study.

scientific article published in April 2016

Relationships Between Calcium Channel Blockers and Vascular Function Tests

scientific article published on 01 June 2019

Response of secondary hyperparathyroidism to cinacalcet depends on parathyroid size

scientific article published on 28 November 2009

Review of the Long-term Effects of Autologous Bone-Marrow Mononuclear Cell Implantation on Clinical Outcomes in Patients with Critical Limb Ischemia

scientific article published on 22 May 2019

Rho-associated kinase activity is a predictor of cardiovascular outcomes.

scientific article

Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome.

scientific article published on 17 August 2015

Serum cross-linked N-terminal telopeptide of type I collagen for evaluation of renal osteodystrophy in hemodialysis patients

scientific article published on 19 January 2005

Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis

scientific article published on 30 September 2018

Switching from epoetin alpha to darbepoetin alpha in Japanese hemodialysis patients: dose conversion ratio

scientific article published on 17 December 2008

TGF-β1 promotes expression of fibrosis-related genes through the induction of histone variant H3.3 and histone chaperone HIRA

scientific article published in Scientific Reports

Telomeric g-tail length and hospitalization for cardiovascular events in hemodialysis patients

scientific article

The serum lipids levels may be underestimated in patients on hemodialysis.

scientific article

Tocilizumab histologically improved AA renal amyloidosis in a patient with multicentric Castleman disease: A case report

Total numbers of undiagnosed carriers of hepatitis C and B viruses in Japan estimated by age- and area-specific prevalence on the national scale.

scientific article

Upstroke Time Is a Useful Vascular Marker for Detecting Patients With Coronary Artery Disease Among Subjects With Normal Ankle-Brachial Index

scientific article published on 26 November 2020

Valproic acid attenuates renal fibrosis through the induction of autophagy.

scientific article published on 7 December 2016

Vascular Function and Intima-media Thickness of a Leg Artery in Peripheral Artery Disease: A Comparison of Buerger Disease and Atherosclerotic Peripheral Artery Disease

scientific article published on 09 May 2016

Vascular function is further impaired in subjects aged 80 years or older

scientific article published on 08 April 2020

Vitamin K₂ alters bone metabolism markers in hemodialysis patients with a low serum parathyroid hormone level

scientific article published on 03 August 2010

pH after the first session of direct hemoperfusion with polymyxin B-immobilized fibers predicts mortality in patients with sepsis and septic shock.

scientific article published on 24 February 2018

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