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List of works by Diana Machado

A case report of disseminated Mycobacterium colombiense infection in an HIV patient

scientific article published on 01 July 2019

Adjuvant therapies against tuberculosis: discovery of a 2-aminothiazole targeting Mycobacterium tuberculosis energetics

scholarly article by Diana Machado et al published September 2018 in Future Microbiology

Advances in the molecular diagnosis of tuberculosis: From probes to genomes

scientific article published on 30 November 2018

An Experimental Model for the Rapid Screening of Compounds with Potential Use Against Mycobacteria

scientific article published on November 2016

Assessment of the BD MGIT TBc identification test for the detection of Mycobacterium tuberculosis complex in a network of mycobacteriology laboratories

scientific article published on 23 January 2014

Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis ⬇️

scientific article published on September 16, 2010

Beyond extensively drug-resistant tuberculosis in Lisbon, Portugal: a case of linezolid resistance acquisition presenting as an iliopsoas abscess

scientific article published on 29 September 2016

Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium

scientific article published on 23 July 2015

Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

scientific article published on 03 July 2018

Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries

article

Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis ⬇️

scientific article published on April 6, 2012

Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex ⬇️

scientific article published on August 17, 2011

Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate

article

Correction: Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus.

scientific article published on 6 June 2013

Direct Detection by the Xpert MTB/RIF Assay and Characterization of Multi and Poly Drug-Resistant Tuberculosis in Guinea-Bissau, West Africa

scientific article

Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains.

scientific article

Emergence of High-Level Colistin Resistance in an Acinetobacter baumannii Clinical Isolate Mediated by Inactivation of the Global Regulator H-NS

scientific article published on 26 June 2018

Emergence of multidrug-resistant Mycobacterium tuberculosis of the Beijing lineage in Portugal and Guinea-Bissau: a snapshot of moving clones by whole-genome sequencing

scientific article published on 01 December 2020

Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil

scientific article published on 28 April 2015

Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum

scientific article published on 10 September 2019

Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus

scientific article

From multidrug-resistant to extensively drug-resistant tuberculosis in Lisbon, Portugal: the stepwise mode of resistance acquisition ⬇️

scientific article published on October 10, 2012

Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola

scientific article

Genetic diversity, transmission dynamics, and drug resistance of Mycobacterium tuberculosis in Luanda, Angola

scientific article published on 12 November 2016

Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance

article

Genomic diversity of drug-resistant Mycobacterium tuberculosis isolates in Lisbon Portugal: Towards tuberculosis genomic epidemiology

article

GidB mutation as a phylogenetic marker for Q1 cluster Mycobacterium tuberculosis isolates and intermediate-level streptomycin resistance determinant in Lisbon, Portugal.

scientific article

Gold nanoprobes for multi loci assessment of multi-drug resistant tuberculosis

scientific article published on 9 January 2014

HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality

scientific article published on 28 September 2017

High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations

scientific article published on 28 March 2013

Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs

scientific article published on September 2012

Insights on Efflux Pumps and Their Implications in Drug Resistance and Virulence

scientific article published on 13 December 2018

Insights on the Mechanism of Action of INH-C10 as an Antitubercular Prodrug.

scientific article published in November 2017

Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs

scientific article published on 24 June 2019

Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis

scientific article

Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis

scientific article

Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally

scientific article published on 9 January 2018

Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli

scientific article published on 26 April 2017

Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants

scientific article published on 04 April 2019

Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections

scientific article published on April 2010

Mycobacterium marinum lymphocutaneous infection

scientific article published on 15 February 2019

Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium

scientific article

Rapid identification of veterinary-relevant Mycobacterium tuberculosis complex species using 16S rDNA, IS6110 and Regions of Difference-targeted dual-labelled hydrolysis probes.

scientific article published on 2 September 2014

Rational Design and Synthesis of Thioridazine Analogues as Enhancers of the Antituberculosis Therapy

scientific article published on 21 July 2015

Relatedness of Mycobacterium avium subspecies hominissuis clinical isolates of human and porcine origins assessed by MLVA.

scientific article

Revisiting susceptibility testing in MDR-TB by a standardized quantitative phenotypic assessment in a European multicentre study.

scientific article

Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance

scientific article published on 2 October 2017

Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections

scientific article published on 01 May 2019

Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery.

scientific article

The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin

scientific article published on 18 September 2019

The role of efflux pumps in macrolide resistance in Mycobacterium avium complex

scientific article published on 8 September 2009

The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs

scientific article

Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal

scientific article published on 13 February 2020

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