List of works - David G. Johnson

A High-Frequency Regulatory Polymorphism in the p53 Pathway Accelerates Tumor Development ⬇️

scientific article published on September 14, 2010

Chromatin: receiver and quarterback for cellular signals

scientific article published on 31 January 2013

Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck

scientific article

Disruption of transcription in vitro and gene expression in vivo by DNA adducts derived from a benzo[a]pyrene diol epoxide located in heterologous sequences.

scientific article published on February 1997

E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair

scientific article published on 30 October 2019

E2F1 and p53 transcription factors as accessory factors for nucleotide excision repair.

scientific article

E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair

scientific article

E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks

scientific article

E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis.

scientific article published on 16 April 2014

E2F2 suppresses Myc-induced proliferation and tumorigenesis.

scientific article

E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

scientific journal article

Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)

scientific article published on June 2009

Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.

scientific article published on November 2005

GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage.

scientific article

INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway ⬇️

scientific article published on September 20, 2010

Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif

scientific article

Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.

scientific article

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

scientific article

Modeling gene-environment interactions in oral cavity and esophageal cancers demonstrates a role for the p53 R72P polymorphism in modulating susceptibility ⬇️

scientific article published on 08 March 2013

Mouse models for the p53 R72P polymorphism mimic human phenotypes

scientific article

Oncogenic capacity of the E2F1 gene

scientific article

Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway.

scientific article published in August 2007

RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1.

scientific article

Regulation of BRCA1 expression by the Rb-E2F pathway

scientific article published in February 2000

Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation.

scientific article published on April 2005

Repression of androgen receptor transcription through the E2F1/DNMT1 axis

scientific article

SAGE profiling of UV-induced mouse skin squamous cell carcinomas, comparison with acute UV irradiation effects.

scientific article

Slug expression in mouse skin and skin tumors is not regulated by p53.

scientific article published on 05 September 2013

The RB-E2F1 pathway regulates autophagy.

scientific article

The p53 R72P polymorphism does not affect the physiological response to ionizing radiation in a mouse model

scientific article published on 8 June 2017

Transcriptional and Nontranscriptional Functions of E2F1 in Response to DNA Damage ⬇️

scientific article published on December 16, 2011

Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors.

scientific article

Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis.

scientific article

Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues

scientific article

List of works by David G. Johnson

A High-Frequency Regulatory Polymorphism in the p53 Pathway Accelerates Tumor Development ⬇️

Chromatin: receiver and quarterback for cellular signals

Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck

Disruption of transcription in vitro and gene expression in vivo by DNA adducts derived from a benzo[a]pyrene diol epoxide located in heterologous sequences.

E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair

E2F1 and p53 transcription factors as accessory factors for nucleotide excision repair.

E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair

E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks

E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis.

E2F2 suppresses Myc-induced proliferation and tumorigenesis.

E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)

Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.

GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage.

INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway ⬇️

Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif

Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

Modeling gene-environment interactions in oral cavity and esophageal cancers demonstrates a role for the p53 R72P polymorphism in modulating susceptibility ⬇️

Mouse models for the p53 R72P polymorphism mimic human phenotypes

Oncogenic capacity of the E2F1 gene

Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway.

RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1.

Regulation of BRCA1 expression by the Rb-E2F pathway

Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation.

Repression of androgen receptor transcription through the E2F1/DNMT1 axis

SAGE profiling of UV-induced mouse skin squamous cell carcinomas, comparison with acute UV irradiation effects.

Slug expression in mouse skin and skin tumors is not regulated by p53.

The RB-E2F1 pathway regulates autophagy.

The p53 R72P polymorphism does not affect the physiological response to ionizing radiation in a mouse model

Transcriptional and Nontranscriptional Functions of E2F1 in Response to DNA Damage ⬇️

Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors.

Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis.

Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues