List of works - Gerald Schwank

Advances in therapeutic CRISPR/Cas9 genome editing

scientific article

Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation.

scientific article published in January 2011

Auxin triggers transient local signaling for cell specification in Arabidopsis embryogenesis

scientific article

CRISPR/Cas9-Mediated Genome Editing of Mouse Small Intestinal Organoids.

scientific article published in January 2016

Comment on "Dynamics of dpp signaling and proliferation control".

scientific article published in January 2012

Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.

scientific article published on 29 May 2018

Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients

scientific article

Generation of BAC transgenic epithelial organoids

scientific article

Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes

scientific article published on 18 February 2020

Growth of Epithelial Organoids in a Defined Hydrogel

scientific article published on 10 September 2018

Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels.

scientific article published in December 2008

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

scientific article

In vivo prime editing of a metabolic liver disease in mice

scientific article published in 2022

Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing

scientific article published on 04 April 2022

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ.

scientific article

Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens

scientific article published on 25 August 2021

Regulation of organ growth by morphogen gradients

scientific article published on January 2010

Replacing the <i>Sp</i>Cas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope

scientific article published on 26 August 2021

Sequential cancer mutations in cultured human intestinal stem cells.

scientific article published on 29 April 2015

Tissue-specific mutation accumulation in human adult stem cells during life

scientific article published on 3 October 2016

miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine

scientific article published on 07 June 2021

List of works by Gerald Schwank

Advances in therapeutic CRISPR/Cas9 genome editing

Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation.

Auxin triggers transient local signaling for cell specification in Arabidopsis embryogenesis

CRISPR/Cas9-Mediated Genome Editing of Mouse Small Intestinal Organoids.

Comment on "Dynamics of dpp signaling and proliferation control".

Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.

Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients

Generation of BAC transgenic epithelial organoids

Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes

Growth of Epithelial Organoids in a Defined Hydrogel

Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels.

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

In vivo prime editing of a metabolic liver disease in mice

Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ.

Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens

Regulation of organ growth by morphogen gradients

Replacing the <i>Sp</i>Cas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope

Sequential cancer mutations in cultured human intestinal stem cells.

Tissue-specific mutation accumulation in human adult stem cells during life

miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine