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List of works by Charlotte K Y Ng

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Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.

scientific article published on 09 July 2014
Chromosomal instability determines taxane response

scholarly article
Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma.

scientific article
Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis

scientific article
Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma.

scientific article
Progression from ductal carcinoma in situ to invasive breast cancer: Revisited

scientific article published on July 12, 2013
Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.

scientific article
Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations

scientific article published on 28 October 2014
Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification

scientific article published on 22 May 2015
Genomic landscape of adenoid cystic carcinoma of the breast

scientific article
A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations

scientific article
Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast

scientific article
Genomic characterization of metastatic breast cancers

scientific article published on 22 May 2019
Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes

scientific article
Breast cancer intratumor genetic heterogeneity: causes and implications

scientific article published on August 1, 2012
Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer.

scientific article
Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

scientific article published on 01 July 2018
The Genomic Landscape of Male Breast Cancers

scientific article published on 9 March 2016
Loss of osteoclasts contributes to development of osteosarcoma pulmonary metastases.

scientific article published on 7 September 2010
The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer

scientific article
The Landscape of Somatic Genetic Alterations in Metaplastic Breast Carcinomas

scientific article published on 2 February 2017
Uterine adenosarcomas are mesenchymal neoplasms.

scientific article published on 23 November 2015
Diverse BRCA1 and BRCA2 Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer

scientific article
Establishing the origin of metastatic deposits in the setting of multiple primary malignancies: the role of massively parallel sequencing

scientific article published on 31 October 2013
Genomic profiling of histological special types of breast cancer

scientific article published on 27 October 2013
The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study

scientific article published on 23 May 2015
Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer

scientific article published on 05 August 2016
A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT)

scientific article published in September 2018
Metaplastic breast carcinomas display genomic and transcriptomic heterogeneity [corrected]. .

scientific article published on 21 November 2014
IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity

scientific article published on 20 October 2016
Metaplastic breast carcinoma: more than a special type

scientific article
PI3K pathway activation in high-grade ductal carcinoma in situ--implications for progression to invasive breast carcinoma

scientific article
HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

scientific article
Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein

scientific article published on 11 May 2015
The protein histidine phosphatase LHPP is a tumour suppressor

scientific article published on 21 March 2018
Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas

scientific article published on 8 May 2018
The Genomic Landscape of Mucinous Breast Cancer

scientific article published on 11 January 2019
Reliability of Whole-Exome Sequencing for Assessing Intratumor Genetic Heterogeneity

scientific article published on 01 November 2018
Bi-allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer.

scientific article published on 15 March 2017
Targeted capture massively parallel sequencing analysis of LCIS and invasive lobular cancer: Repertoire of somatic genetic alterations and clonal relationships

scientific article
Are acinic cell carcinomas of the breast and salivary glands distinct diseases?

scientific article published on 16 February 2015
A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer

scientific article
Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations

scientific article published on 9 May 2018
The Role of Long Non-Coding RNAs in Hepatocarcinogenesis

scientific article published on 28 February 2018
Lobular Carcinomas In Situ Display Intralesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Lobular Carcinoma

scientific article published on 05 September 2018
High expression of HOXA13 correlates with poorly differentiated hepatocellular carcinomas and modulates sorafenib response in in vitro models

scientific article
Resolving quandaries: basaloid adenoid cystic carcinoma or breast cylindroma? The role of massively parallel sequencing.

scientific article
Microglandular adenosis associated with triple-negative breast cancer is a neoplastic lesion of triple-negative phenotype harbouring TP53 somatic mutations

scientific article published on 25 January 2016
Gene expression profiling of lobular carcinoma in situ reveals candidate precursor genes for invasion

scientific article published on December 24, 2014
Response to dual HER2 blockade in a patient with HER3-mutant metastatic breast cancer

scientific article published on 7 May 2015

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