List of works by Mitchell Kronenberg

A 'GEM' of a cell

scientific article published in July 2013

A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity

scientific article

A Novel Glycolipid Antigen for NKT Cells That Preferentially Induces IFN-γ Production

scientific article

A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice

scientific article published on 16 December 2016

A crucial role for HVEM and BTLA in preventing intestinal inflammation

scientific article published on 2 June 2008

A method for production of recombinant mCD1d protein in insect cells

scientific article

A murine model of NKT cell-mediated liver injury induced by alpha-galactosylceramide/d-galactosamine

scientific article published on 20 May 2005

A new mouse strain for the analysis of invariant NKT cell function

scientific article

A novel role for IL-27 in mediating the survival of activated mouse CD4 T lymphocytes

scientific article published on 18 January 2013

A unique lymphotoxin {alpha}beta-dependent pathway regulates thymic emigration of V{alpha}14 invariant natural killer T cells

scholarly article

ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content

scientific article published on 16 January 2017

ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development

scientific article published on 24 October 2012

Abrogation of anti-retinal autoimmunity in IL-10 transgenic mice due to reduced T cell priming and inhibition of disease effector mechanisms

scientific article published on April 2008

Activation and Function of iNKT and MAIT Cells

scientific article published on 25 April 2015

Activation of invariant NKT cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-gamma production and dampening of the adaptive Th1 and Th17 responses

scientific article published on October 2008

Activation of natural killer T cells by glycolipids

scientific article published on January 2006

Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus ⬇️

scientific article published on October 1, 2003

Activation or anergy: NKT cells are stunned by alpha-galactosylceramide

scientific article published on September 2005

Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70.

scientific article published on 6 July 2018

Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice

scientific article published in August 2006

Antigen specificity of invariant natural killer T-cells

scientific article

Antigen-dependent versus -independent activation of invariant NKT cells during infection

scientific article

Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency

scientific article

Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis.

scientific article published on 15 March 2018

BTLA interaction with HVEM expressed on CD8(+) T cells promotes survival and memory generation in response to a bacterial infection

scientific article (publication date: 2013)

Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells

scientific article

CD1 and MHC II find different means to the same end.

scientific article

CD1 mediated T cell recognition of glycolipids

scientific article published on 24 October 2007

CD1 tetramers: a powerful tool for the analysis of glycolipid-reactive T cells

scientific article

CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells

scientific article

CD1d-restricted peripheral T cell lymphoma in mice and humans

scientific article published on 11 April 2016

CD1d1 displayed on cell size beads identifies and enriches an NK cell population negatively regulated by CD1d1.

scientific article published on May 2004

CD4+ CD25+ T cells responding to serologically defined autoantigens suppress antitumor immune responses

scientific article

CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma.

scientific article

Carbohydrate specificity of the recognition of diverse glycolipids by natural killer T cells

scientific article published on July 2009

Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection

scientific article

Commensal microbiota and CD8+ T cells shape the formation of invariant NKT cells

scientific article

Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function ⬇️

scientific article published on October 6, 2003

Cooling the fires of inflammation

scientific article

Cross-presentation of disialoganglioside GD3 to natural killer T cells

scientific article

Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: a molecular basis for NKT cell activation

scientific article published on July 2005

Cutaneous immunization rapidly activates liver invariant Valpha14 NKT cells stimulating B-1 B cells to initiate T cell recruitment for elicitation of contact sensitivity

scientific article

Cutting edge: CD4+CD25+ regulatory T cells impaired for intestinal homing can prevent colitis.

scientific article published in June 2005

Cutting edge: activation by innate cytokines or microbial antigens can cause arrest of natural killer T cell patrolling of liver sinusoids

scientific article

Cutting edge: the mechanism of invariant NKT cell responses to viral danger signals

scientific article published on October 2008

Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d

scholarly article

Detection of microbes by natural killer T cells.

scientific article published on January 2009

Development of Asthma in Inner-City Children: Possible Roles of MAIT Cells and Variation in the Home Environment

scientific article published on 5 February 2018

Disruption of T helper 2-immune responses in Epstein-Barr virus-induced gene 3-deficient mice

scientific article

Distinct requirements for activation of NKT and NK cells during viral infection

scientific article published on 14 March 2014

Diverse endogenous antigens for mouse NKT cells: self-antigens that are not glycosphingolipids

scientific article

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity

scientific article

Exosome-like nanoparticles from intestinal mucosal cells carry prostaglandin E2 and suppress activation of liver NKT cells

scientific article

Expansion of human Valpha24+ NKT cells by repeated stimulation with KRN7000.

scientific article published in February 2004

Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection

scientific article

Frontline T cells: gammadelta T cells and intraepithelial lymphocytes

scientific article published on February 2007

Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells

scholarly article

Glycolipids that Elicit IFN-γ-Biased Responses from Natural Killer T Cells

scientific article

Going both ways: immune regulation via CD1d-dependent NKT cells

scientific article published in November 2004

HSV-1 latency and the kinetics of reactivation are regulated by a complex network of interactions between HVEM, its ligands (gD, BTLA, LIGHT and CD160) and LAT

scientific article published on 27 November 2018

HVEM is a TNF Receptor with Multiple Regulatory Roles in the Mucosal Immune System

scientific article

HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria

scientific journal article

HVEM: An unusual TNF receptor family member important for mucosal innate immune responses to microbes

scientific article published on 18 January 2013

Helicobacter pylori cholesteryl α-glucosides contribute to its pathogenicity and immune response by natural killer T cells

scientific article published on 02 December 2013

Hepatic stellate cells function as regulatory bystanders

scientific article published on April 2011

IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2.

scientific article published on 3 March 2005

IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset

scientific article published on 25 July 2014

Immunology: oiling the wheels of autoimmunity.

scientific article

Improved Detection of Cytokines Produced by Invariant NKT Cells

scientific article published on 30 November 2017

Infection, autoimmunity, and glycolipids: T cells detect microbes through self-recognition

scientific article published in June 2005

Innate-like recognition of microbes by invariant natural killer T cells

scientific article published on 29 July 2009

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

scientific article

Interleukin-27 receptor limits atherosclerosis in Ldlr-/- mice

scientific article published on 27 August 2012

Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells

scientific article published on 21 February 2012

Interruption of CXCL13-CXCR5 axis increases upper genital tract pathology and activation of NKT cells following chlamydial genital infection

scientific article

Interview: glycolipid antigen presentation by CD1d and the therapeutic potential of NKT cell activation

scientific article published on 31 December 2007

Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice

scientific article

Intestinal mucus-derived nanoparticle-mediated activation of Wnt/β-catenin signaling plays a role in induction of liver natural killer T cell anergy in mice

scientific article published on 11 February 2013

Intrathymic NKT cell development is blocked by the presence of alpha-galactosylceramide

scientific article published on July 2003

Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids

scientific article

Invariant NKT cells amplify the innate immune response to lipopolysaccharide.

scientific article published in March 2007

Invariant NKT cells are required for airway inflammation induced by environmental antigens

scientific article

Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation

scientific article published on 29 April 2015

Invariant natural killer T cells are depleted in renal impairment and recover after kidney transplantation

scientific article published on 18 December 2013

Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

scientific article

Invariant natural killer T cells: front line fighters in the war against pathogenic microbes

scientific article published on July 2016

Invariant natural killer cells in the response to bacteria: the advent of specific antigens

scientific article published on October 2006

LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection

scholarly article published by Mitchell Kronenberg in 2018

Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d-restricted NKT cells.

scientific article

Lipid and Carbohydrate Modifications of α-Galactosylceramide Differently Influence Mouse and Human Type I Natural Killer T Cell Activation

scientific article published on 27 May 2015

Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells

scientific article

Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice

scientific article

MAITs onstage in mice and men with three acts for development

scientific article published on 8 November 2016

Making memory at birth: understanding the differentiation of natural killer T cells

scientific article published on 2 February 2012

Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by V 14i NKT Cells

scientific article

Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets

scientific article

Mo1735 Mechanism of Immune Regulation by CD11b+ Myeloid Cells in the Intestine

Molecular basis for the high affinity interaction between the thymic leukemia antigen and the CD8alphaalpha molecule

scientific journal article

Mouse TCRalphabeta+CD8alphaalpha intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses.

scientific article published in April 2007

Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo

scientific article

Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae

scientific article published in Nature Communications

Mucosal T lymphocytes--peacekeepers and warriors

scientific article

Mucosal memory CD8⁺ T cells are selected in the periphery by an MHC class I molecule

scientific article published on 2 October 2011

Murine Corneal Inflammation and Nerve Damage After Infection With HSV-1 Are Promoted by HVEM and Ameliorated by Immune-Modifying Nanoparticle Therapy

scientific article published on January 2017

NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells

scientific article

NKG2A inhibits invariant NKT cell activation in hepatic injury

scientific article

NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi

scholarly article

NKT cells: what's in a name?

scientific article published in March 2004

NKT10 cells: a novel iNKT cell subset

scientific article published on 26 August 2015

Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells

scientific article

Natural killer T cell ligand alpha-galactosylceramide enhances protective immunity induced by malaria vaccines

scientific article

Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis

scientific article published in February 2008

Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria

scientific article published on 20 August 2006

Natural killer T cells: know thyself

scholarly article

Natural killer T cells: natural or unnatural regulators of autoimmunity?

scientific article published on December 2003

Neutrophilic granulocytes modulate invariant NKT cell function in mice and humans

scientific article published on 2 March 2012

OMIP-030: Characterization of human T cell subsets via surface markers

scientific article published on 27 October 2015

On the road: progress in finding the unique pathway of invariant NKT cell differentiation

scientific article published on 15 February 2007

Paradoxical effect of reduced costimulation in T cell-mediated colitis.

scientific article published in May 2007

Peptide-independent folding and CD8 alpha alpha binding by the nonclassical class I molecule, thymic leukemia antigen

scientific article

Phenotypical and functional alterations during the expansion phase of invariant Valpha14 natural killer T (Valpha14i NKT) cells in mice primed with alpha-galactosylceramide.

scientific article published in September 2005

Phospholipid signals of microbial infection for the human immune system

scientific article

Presenting fats with SAPs

scientific article published in February 2004

Production of α-galactosylceramide by a prominent member of the human gut microbiota ⬇️

scientific article (publication date: July 2013)

Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs.

scientific article

Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants

scientific article published on 21 December 2020

Protein kinase C-η controls CTLA-4-mediated regulatory T cell function

scientific article

Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer

scientific article published in October 2002

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

scientific article

Recognition of bacterial glycosphingolipids by natural killer T cells

scientific article published in March 2005

Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners

scientific article published on 03 June 2009

Regulation of immunity by self-reactive T cells

scientific article

Regulation of inflammation, autoimmunity, and infection immunity by HVEM-BTLA signaling

scientific article

Regulation of mucosal immune responses by recombinant interleukin 10 produced by intestinal epithelial cells in mice

scientific article published in June 2002

Response to Comment on “Development of Asthma in Inner-City Children: Possible Roles of MAIT Cells and Variation in the Home Environment”

scientific article published on 01 May 2018

Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells

scientific article published on April 2009

Role of MAIT cells in pulmonary bacterial infection

Role of NKT cells in the digestive system. IV. The role of canonical natural killer T cells in mucosal immunity and inflammation

scientific article published on 18 October 2007

S1725 Interleukin 10 Acts on Regulatory T Cells to Maintain FOXP3 Expression and Suppressive Function in Mice With Colitis

Salmonella typhimurium infection halts development of type 1 diabetes in NOD mice

scientific article published in November 2004

Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes

scientific article

Selective Conditions Are Required for the Induction of Invariant NKT Cell Hyporesponsiveness by Antigenic Stimulation

scientific article published on 9 September 2015

Spontaneous colitis occurrence in transgenic mice with altered B7-mediated costimulation

scientific article published on October 2008

Surface receptors identify mouse NK1.1+ T cell subsets distinguished by function and T cell receptor type

scientific article

Surprisingly minor influence of TRAV11 (Valpha14) polymorphism on NK T-receptor mCD1/alpha-galactosylceramide binding kinetics

scientific article published on 14 February 2003

Synergistic costimulation by both B7 molecules regulates colitis pathogenesis

scientific article published on August 2006

Synthesis and evaluation of 3''- and 4''-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000.

scientific article published on 6 June 2009

Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH.

scientific article published in December 2005

Synthesis of a 2"-deoxy-β-GalCer

scientific article

T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment

scientific article

TSC1 regulates the balance between effector and regulatory T cells

scientific article

Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation

scientific article published on 22 April 2013

The Alpha and Omega of Galactosylceramides in T Cell Immune Function

scientific article published on 6 May 2015

The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition

scholarly article

The Third Way: Progress on pathways of antigen processing and presentation by CD1.

scientific article published on June 2004

The Tumor Necrosis Factor Superfamily Members TNFSF14 (LIGHT), Lymphotoxin β and Lymphotoxin β Receptor Interact to Regulate Intestinal Inflammation

The V alpha 14 NKT cell TCR exhibits high-affinity binding to a glycolipid/CD1d complex.

scientific article published in August 2002

The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode

scientific article

The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cells

scientific journal article

The alpha and omega of galactosylceramides in T cell immune function.

scientific article published in August 2015

The complementarity determining region 2 of BV8S2 (V beta 8.2) contributes to antigen recognition by rat invariant NKT cell TCR.

scientific article published on June 2006

The crystal structure of a TL/CD8alphaalpha complex at 2.1 A resolution: implications for modulation of T cell activation and memory

scientific article (publication date: February 2003)

The identification of the endogenous ligands of natural killer T cells reveals the presence of mammalian α-linked glycosylceramides

scientific article

The mouse CD1d cytoplasmic tail mediates CD1d trafficking and antigen presentation by adaptor protein 3-dependent and -independent mechanisms.

scientific article published on March 2005

The proatherogenic role of T cells requires cell division and is dependent on the stage of the disease

scientific article published in December 2005

The role of innate immunity in autoimmunity.

scientific article published on December 2004

The role of invariant natural killer T cells in microbial immunity

scientific article published on 12 July 2013

The roles of 3' and 4' hydroxy groups in alpha-galactosylceramide stimulation of invariant natural killer T cells

scientific article

The transcription factor NR4A3 controls CD103+ dendritic cell migration

scientific article

The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells

scientific article

The tumor necrosis factor family member TNFSF14 (LIGHT) is required for resolution of intestinal inflammation in mice

scientific article

The unconventional lifestyle of NKT cells

scientific article

The unique role of natural killer T cells in the response to microorganisms

scientific article published on 8 May 2007

Therapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responses

scientific article published on December 2014

Thymic differentiation of TCR alpha beta(+) CD8 alpha alpha(+) IELs

scientific article published on February 2007

Tissue-specific functions of invariant natural killer T cells

Toward an understanding of NKT cell biology: progress and paradoxes

scientific article

Transcriptional control of the development and function of Vα14i NKT cells

scientific article published on January 2014

Transcriptional regulator Id2 controls survival of hepatic NKT cells

scientific article

Transcriptional reprogramming of mature CD4⁺ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes

scientific article published on 20 January 2013

Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure

scientific article published on 04 March 2021

Unconventional ligand activation of herpesvirus entry mediator signals cell survival

scholarly article

Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells

scientific article

V alpha14 i NKT cells are innate lymphocytes that participate in the immune response to diverse microbes

scientific article

Villous B cells of the small intestine are specialized for invariant NK T cell dependence

scientific article published on April 2008

When Insult Is Added to Injury: Cross Talk between ILCs and Intestinal Epithelium in IBD

scientific article

When less is more: T lymphocyte populations with restricted antigen receptor diversity

scientific article

αβT cell receptors expressed by CD4(-)CD8αβ(-) intraepithelial T cells drive their fate into a unique lineage with unusual MHC reactivities

scientific article

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