List of works by Kathy K. Griendling

ATVB In Focus

scientific article published on 01 February 2005

Agonist-induced phosphorylation of the vascular type 1 angiotensin II receptor

scientific article

Angiotensin II Type 1 Receptor

scientific article published on 01 September 1998

Angiotensin II and NADPH oxidase increase ADMA in vascular smooth muscle cells

scientific article

Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system

scientific article published on 26 July 2006

Angiotensin II receptor pharmacology.

scientific article published on January 1994

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells

scientific article published on 01 June 1994

Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators

scientific article

Angiotensin II stimulation of vascular smooth muscle cells. Secondary signalling mechanisms.

scientific article

Angiotensin II, from vasoconstrictor to growth factor: a paradigm shift

scientific article published on February 2014

Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle

scientific article published on 2 September 2004

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone

scientific article

Angiotensin II–Induced Hypertension Increases Heme Oxygenase-1 Expression in Rat Aorta

scientific article published on 01 September 1997

Angiotensin-ll-and Endothelin-lnduced Protein Phosphorylation in Cultured Vascular Smooth Muscle Cells

scientific article published on 01 September 1993

Anti-inflammatory and antiatherogenic role of BMP receptor II in endothelial cells

scientific article published on 04 April 2013

Arachidonic Acid Metabolites Mediate Angiotensin II-Induced NADH/NADPH Oxidase Activity and Hypertrophy in Vascular Smooth Muscle Cells

scientific article published on 01 January 1999

Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury

scientific article published on February 2007

Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system

scientific article

Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase

scientific article published on 23 September 2004

C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils

scientific article published on 12 April 2004

Career development of physician scientists: a survey of leaders in academic medicine

scientific article published in August 2011

Cell transformation by the superoxide-generating oxidase Mox1

scientific article

Chemiluminescence and the Nox1-Nox2-Nox4 Triple Knockout

scientific article published on 9 June 2015

Cholesterol depletion inhibits epidermal growth factor receptor transactivation by angiotensin II in vascular smooth muscle cells: role of cholesterol-rich microdomains and focal adhesions in angiotensin II signaling.

scientific article

Circulation Research Editors’ Annual Report for 2004

Circulation Research Editors’ Yearly Report: 2003

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

scientific article

Cyclic Strain and Hypertension Increase Osteopontin Expression in the Aorta.

scientific article published on 27 December 2016

Cytochrome b-558 alpha-subunit cloning and expression in rat aortic smooth muscle cells

scientific article

Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4.

scientific article published on 17 December 2017

Differential effects of AT1 receptor and Ca2+ channel blockade on atherosclerosis, inflammatory gene expression, and production of reactive oxygen species

scientific article

Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4.

scientific article published on 7 April 2005

Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase

scientific article

Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production

scientific article

Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells

scientific article

Dual Role of Reactive Oxygen Species in Vascular Growth

scientific article published on 01 September 1999

Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells

scientific article

Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass

scientific article

Electron spin resonance characterization of the NAD(P)H oxidase in vascular smooth muscle cells.

scientific article published in March 2001

Endothelin A and B receptors are down-regulated in the hearts of hypertensive rats

scientific article published on March 1994

Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells.

scientific article published in April 2001

Erratum

scholarly article published in Free Radical Biology and Medicine

Expression of inducible nitric-oxide synthase and intracellular protein tyrosine nitration in vascular smooth muscle cells: role of reactive oxygen species

scientific article published on 10 April 2003

FGF Suppresses Poldip2 Expression in Osteoblasts

scientific article published on 5 December 2016

Functional association of nox1 with p22phox in vascular smooth muscle cells

scientific article published in November 2004

Functional evaluation of nonphagocytic NAD(P)H oxidases

scientific article

Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association

scientific article

G Protein-coupled Receptor Kinase 5 in Cultured Vascular Smooth Muscle Cells and Rat Aorta

scientific article published on 01 December 1997

Heme Oxygenase-1 Is Regulated by Angiotensin II in Rat Vascular Smooth Muscle Cells

scientific article published on 01 March 1997

Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice

scientific article published on 7 October 2004

Hic-5 Mediates TGFβ-Induced Adhesion in Vascular Smooth Muscle Cells by a Nox4-Dependent Mechanism

scientific article published on 26 March 2015

Hydrogen peroxide down-regulates inositol 1,4,5-trisphosphate receptor content through proteasome activation.

scientific article published on 24 July 2009

Hydrogen peroxide regulates osteopontin expression through activation of transcriptional and translational pathways

scientific article

Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: role of protein kinase C.

scientific article published on March 1993

Increased NADH-Oxidase–Mediated Superoxide Production in the Early Stages of Atherosclerosis

scientific article published on 01 April 1999

Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9.

scientific article published on 15 March 2012

Inhibition of vascular cell growth by X-ray irradiation: comparison with gamma radiation and mechanism of action

scientific article published on 01 June 2001

Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells

scientific article published on 02 January 2009

Lack of long-term protective effect of antioxidant/anti-inflammatory therapy in transplant-induced ischemia/reperfusion injury

scientific article published on 24 May 2006

Measurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System: A Scientific Statement From the American Heart Association

scientific article

Measurement of reactive oxygen species in cardiovascular studies

scientific article

Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor

scientific journal article

Mechanism of Hydrogen Peroxide-Induced Cell Cycle Arrest in Vascular Smooth Muscle

scientific article published on 01 October 2002

Mechanisms of reactive oxygen species-dependent downregulation of insulin receptor substrate-1 by angiotensin II.

scientific article published on 31 March 2005

Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation

scientific article published on 15 January 2009

Modulation of extracellular superoxide dismutase expression by angiotensin II and hypertension

scientific article

Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology

scientific article

Modulation of vascular smooth muscle signaling by reactive oxygen species

scientific article published on August 2006

Molecular Pathways of Smooth Muscle Disease

Mycophenolic Acid Is a New Nox2 Inhibitor

scientific article published on 13 November 2006

NAD(P)H oxidase-derived reactive oxygen species as mediators of angiotensin II signaling

scientific article

NAD(P)H oxidase: role in cardiovascular biology and disease

scientific article (publication date: 17 March 2000)

NAD(P)H oxidases and their relevance to atherosclerosis

scientific article

NADH/NADPH Oxidase and Vascular Function

scientific article published on 01 November 1997

NADPH Oxidases and Measurement of Reactive Oxygen Species

scientific article published in January 2017

NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor ⬇️

scientific article published on November 11, 2010

NADPH oxidase inhibitors: new antihypertensive agents?

scientific article published on July 2007

NADPH oxidases and angiotensin II receptor signaling

scientific article

NADPH oxidases: functions and pathologies in the vasculature

scientific article

NADPH oxidases: molecular understanding finally reaching the clinical level?

scientific article

NADPH oxidases: new regulators of old functions

scientific article published in September 2006

NADPH oxidases: progress and opportunities

scientific article

NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis

scientific article published on 18 July 2016

Nox is playing with a full deck in vascular smooth muscle

scientific article published on 06 May 2006

Nox proteins in signal transduction

scientific article published on 21 July 2009

Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice

scientific article

Nox1-based NADPH oxidase-derived superoxide is required for VSMC activation by advanced glycation end-products

scientific article published on 12 February 2007

Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension

scientific article published on 30 October 2013

Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression

scientific article published on 16 June 2008

Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype

scientific article published on 2 November 2006

Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells

scientific article published on 26 April 2008

Nuclear factor (erythroid-derived 2)-like 2, the brake in oxidative stress that nicotinamide adenine dinucleotide phosphate-oxidase-4 needs to protect the heart

scientific article published on 22 December 2014

Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase

scientific article published in June 1998

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion

scientific article published on 4 September 2003

Out, damned dot: studies of the NAD(P)H oxidase in atherosclerosis

Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.

scientific article published on 22 February 2007

Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling

scientific article

Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS.

scientific article published on October 2003

Oxidative stress and cardiovascular injury: Part II: animal and human studies

scientific article

Oxidative stress and diabetic cardiovascular complications

scientific article

Peroxisome proliferator-activated receptor-gamma ligands regulate endothelial membrane superoxide production

scientific article published on 8 December 2004

Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration

scientific article published in April 2004

Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells.

scientific article

Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction

scientific article published on 10 March 2021

Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization

scientific article

Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer.

scientific article published on 6 February 2018

Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts

scientific journal article

Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells

scientific journal article

Polymerase delta interacting protein 2 sustains vascular structure and function.

scientific article published on 03 July 2013

Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain

scientific article published on 17 February 2018

Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells

scientific article published on 19 January 2016

Polymerase δ-interacting Protein 2: A Multifunctional Protein

scientific article published on June 2017

Polymerase δ-interacting protein 2 promotes postischemic neovascularization of the mouse hindlimb

scientific article

Prevention of abdominal aortic aneurysm by anti-microRNA-712 or anti-microRNA-205 in angiotensin II-infused mice

scientific journal article

Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression: implication for native LDL oxidation

scientific article published on 30 October 2003

Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions

scientific article

RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response

scientific journal article

Reactive oxygen species as mediators of angiotensin II signaling

scientific article

Reactive oxygen species in hypertension; An update

scientific article published in September 2004

Reactive oxygen species in the vasculature: molecular and cellular mechanisms

scientific article published on 27 October 2003

Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells

scientific article

Reactive oxygen species signaling in vascular smooth muscle cells

scientific article

Reactive oxygen species, NADPH oxidases, and hypertension

scientific article

Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes

article

Redox Control of Growth Factor Signaling in Heart, Lung, and Circulation

scientific article published on 01 December 2003

Redox control of vascular smooth muscle migration

scientific article

Redox control of vascular smooth muscle proliferation

scientific article published on 01 July 1998

Redox regulation of the actin cytoskeleton and its role in the vascular system

scientific article published on 8 March 2017

Redox signaling, vascular function, and hypertension

scientific article

Redox-Sensitive Regulation of Myocardin-Related Transcription Factor (MRTF-A) Phosphorylation via Palladin in Vascular Smooth Muscle Cell Differentiation Marker Gene Expression

scientific article

Regional differences in alpha 1-adrenoceptor numbers and responses in canine aorta ⬇️

scientific article published on 01 December 1984

Regulation of signal transduction by reactive oxygen species in the cardiovascular system

scientific article

Relation between alpha adrenergic receptor occupation and contractile response: radioligand and physiologic studies in canine aorta ⬇️

scientific article published on 01 June 1984

Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells

scientific article published in April 2003

Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: role of Gab1 and Shp2.

scientific article

Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells

scientific article published in October 2002

RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species

scientific article

Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy

scientific article published on September 1998

Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells

scientific article

Role of oxidative stress in atherosclerosis

scientific article

Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells

scientific article

Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II.

scientific article published in February 2007

Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides.

scientific article published on 20 March 2003

Superoxide and hydrogen peroxide counterregulate myogenic contractions in renal afferent arterioles from a mouse model of chronic kidney disease

scientific article published on 7 April 2017

Superoxide production and expression of nox family proteins in human atherosclerosis

scientific article published in March 2002

The A640G and C242T p22(phox) polymorphisms in patients with coronary artery disease

scientific article published in August 2002

The bone morphogenic protein inhibitor, noggin, reduces glycemia and vascular inflammation in db/db mice

scientific article published on 28 June 2013

The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases

scientific article

The yin/yang of superoxide dismutase mimetics: potential cardiovascular therapies?

scientific article

Thrombin: beyond coagulation

scientific article published on 01 January 2004

Transforming growth factor β inhibits platelet derived growth factor-induced vascular smooth muscle cell proliferation via Akt-independent, Smad-mediated cyclin D1 downregulation

scientific article

Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury

scientific article published in January 2002

Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling

scientific article

Vascular Smooth Muscle

Vascular Thrombin Receptor Regulation in Hypertensive Rats

scientific article published on 01 June 1997

Vascular hypertrophy in angiotensin II-induced hypertension is mediated by vascular smooth muscle cell-derived H2O2.

scientific article published on 19 September 2005

Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNK

scientific article published on 7 September 2011

Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat

scientific journal article

Zinc regulates Nox1 expression through a NF-κB and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells.

scientific article published on 29 March 2017

p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats

scientific article

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