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List of works by Alexander Hein

A Review of Integrative Medicine in Gynaecological Oncology

scientific article

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

scientific article published on 18 June 2018

ABCA transporter gene expression and poor outcome in epithelial ovarian cancer

scientific article

Abstract 5488: Utilizing a pathway based analysis of genome wide association data to identify biomarkers of toxicity in breast cancer patients

article

Accuracy of radiological tumour size assessment and the risk for re-excision in a cohort of primary breast cancer patients

scientific article published on 26 October 2011

Amplified Cold Transduction in Native Nociceptors by M-Channel Inhibition

scientific article published on 01 October 2013

Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome

scientific article published on 19 March 2013

Arbeitsgruppe Integrative Medizin (AG IMed) der AGO e.V.. Begriffsdefinition, Gründung, Ziele und Perspektiven der AG Integrative Medizin

Assessing the genetic architecture of epithelial ovarian cancer histological subtypes

scientific article

Assessment of mammographic density before and after first full-term pregnancy

scientific article published on 01 November 2010

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

scientific article published on 21 June 2016

Association analysis identifies 65 new breast cancer risk loci.

scientific article published on 23 October 2017

Association between mammographic density and pregnancies relative to age and BMI: a breast cancer case-only analysis

scientific article

Association of molecular subtypes with breast cancer risk factors: a case-only analysis

scientific article published on 9 December 2014

Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study

scientific article published on 4 September 2016

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

article by Xiang Shu et al published 1 October 2018 in International Journal of Epidemiology

Body mass index and breast cancer survival: a Mendelian randomization analysis

scientific article published in December 2017

Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis

scientific article published on December 2013

Breast Cancer Risk - Genes, Environment and Clinics

scientific article

Breast cancer risk assessment in a mammography screening program and participation in the IBIS-II chemoprevention trial

scientific article published on 21 March 2010

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer

scientific article

Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk

scientific article published in February 2015

Characterizing mammographic images by using generic texture features

scientific article

Chylous ascites after lymphadenectomy for gynecological malignancies

scientific article

Circulating micro-RNAs as potential blood-based markers for early stage breast cancer detection

scientific article published in 2012

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

scientific article published on 22 September 2015

Clinical validation of genetic variants associated with in vitro chemotherapy-related lymphoblastoid cell toxicity

scientific article published on 9 May 2017

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

scientific article published on 19 June 2015

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).

scientific article

Common germline polymorphisms associated with breast cancer-specific survival

scientific article published on 22 April 2015

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

scientific article

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

scientific article

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article

Competitive analysis of pregnancy associated HLA-proteins in trophoblast and breast cancer tissue

Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer

scientific article published in October 2015

Comprehensive visualization of paresthesia in breast cancer survivors

scientific article

Computerized patient identification for the EMBRACA clinical trial using real-time data from the PRAEGNANT network for metastatic breast cancer patients

scientific article

Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk

scientific article

Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article published in PLoS ONE

Cross-cancer genome-wide association study of endometrial cancer and epithelial ovarian cancer identifies genetic risk regions associated with risk of both cancers

scientific article published on 03 November 2020

Diabetes and prognosis in a breast cancer cohort

scientific article published on 05 December 2010

Dose adjustment of cisplatin, etoposide, and ifosfamide according to kidney function: a retrospective analysis and implications for medication safety

scientific article published on 2 January 2018

Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

scientific article published on 12 October 2017

Endometriosis as a risk factor for ovarian or endometrial cancer - results of a hospital-based case-control study

scientific article published on 21 October 2015

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk

scientific article

Estrogen receptor beta rs1271572 polymorphism and invasive ovarian carcinoma risk: pooled analysis within the Ovarian Cancer Association Consortium

scientific article

Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study

scientific article published on 17 December 2014

Evaluation of Therapy Management and Patient Compliance in Postmenopausal Patients with Hormone Receptor-positive Breast Cancer Receiving Letrozole Treatment: The EvaluateTM Study

scientific article

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk

scientific article published on 27 October 2011

Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium study

scientific article

Expression of neuroendocrine markers in different molecular subtypes of breast carcinoma

scientific article published on 19 February 2014

Factors Influencing Decision-Making for or against Adjuvant and Neoadjuvant Chemotherapy in Postmenopausal Hormone Receptor-Positive Breast Cancer Patients in the EvAluate-TM Study

scientific article

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk

scientific article

Five endometrial cancer risk loci identified through genome-wide association analysis

scientific article published on 02 May 2016

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013

Genetic Breast Cancer Susceptibility Variants and Prognosis in the Prospectively Randomized SUCCESS A Study

scientific article published on 28 June 2017

Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer

scientific article published on 22 August 2016

Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses

scientific article published on 2 April 2018

Genetic variants in VEGF pathway genes in neoadjuvant breast cancer patients receiving bevacizumab: Results from the randomized phase III GeparQuinto study

scientific article published on 23 June 2015

Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium

scientific article

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer

scientific article published on 9 December 2013

Genome-wide association study identifies a common variant associated with risk of endometrial cancer

scientific article

Genome-wide association study identifies a possible susceptibility locus for endometrial cancer

scientific article

Genome-wide association study of germline variants and breast cancer-specific mortality

scientific article published on 21 February 2019

Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.

scientific article published on 5 November 2013

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer

scientific article published on 31 January 2016

HLA-G and HLA-F protein isoform expression in breast cancer patients receiving neoadjuvant treatment

scientific article published on 25 September 2020

Hormone Therapy and its Effect on the Prognosis in Breast Cancer Patients

scientific article published in June 2015

Hormone replacement therapy and prognosis in ovarian cancer patients

scientific article published in January 2013

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of nine new susceptibility loci for endometrial cancer

scientific article published in Nature Communications

Identification of novel genetic markers of breast cancer survival

scientific article published on 18 April 2015

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Incorporating progesterone receptor expression into the PREDICT breast prognostic model

scientific article published in 2022

Influence of patient and tumor characteristics on early therapy persistence with letrozole in postmenopausal women with early breast cancer: results of the prospective Evaluate-TM study with 3941 patients

scientific article published on 10 October 2017

Influence of side-effects on early therapy persistence with letrozole in post-menopausal patients with early breast cancer: Results of the prospective EvAluate-TM study

scientific article published on 18 April 2018

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

scientific article

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

scientific article published on 25 February 2016

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

scientific article published on 01 April 2017

Interest in Integrative Medicine Among Postmenopausal Hormone Receptor-Positive Breast Cancer Patients in the EvAluate-TM Study

scientific article

Knowledge and attitudes regarding medical research studies among patients with breast cancer and gynecological diseases

scientific article published on 14 August 2015

Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome

scientific article published on 27 January 2014

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

scientific article

Mammographic density as a risk factor for breast cancer in a German case–control study

article

Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer

scientific article published on 13 July 2020

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

scientific article

Morphological characterization of rat Mas-related G-protein-coupled receptor C and functional analysis of agonists.

scientific article published on 4 November 2007

Mutation status of the mediator complex subunit 12 (MED12) in uterine leiomyomas and concurrent/metachronous multifocal peritoneal smooth muscle nodules (leiomyomatosis peritonealis disseminata).

scientific article

Neoadjuvant Treatment of Breast Cancer - Advances and Limitations

scientific article published on 24 October 2016

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

scientific article

No Evidence That Genetic Variation in the Myeloid-Derived Suppressor Cell Pathway Influences Ovarian Cancer Survival

scientific article published on 27 September 2016

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

Outcome and prognosis in uterine sarcoma and malignant mixed Mullerian tumor

scientific article published on 28 December 2015

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

Pathway-Based Analysis of Genome-Wide Association Data Identified SNPs in HMMR as Biomarker for Chemotherapy- Induced Neutropenia in Breast Cancer Patients

scientific article published on 13 March 2018

Percent Mammographic Density and Dense Area as Risk Factors for Breast Cancer

scientific article

Phenotyping sensory nerve endings in vitro in the mouse

scientific article

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

scientific article

Polymorphisms in inflammation pathway genes and endometrial cancer risk

scientific article published on 5 December 2012

Polymorphisms in the RANK/RANKL genes and their effect on bone specific prognosis in breast cancer patients

scientific article published on 5 March 2014

Pooled analysis of the prognostic relevance of progesterone receptor status in five German cohort studies

article

Predicting Triple-Negative Breast Cancer Subtype Using Multiple Single Nucleotide Polymorphisms for Breast Cancer Risk and Several Variable Selection Methods

scientific article published on 28 June 2017

Prognostic relevance of Ki-67 in the primary tumor for survival after a diagnosis of distant metastasis

scientific article published on 12 March 2013

Response to "screening depression during and after pregnancy using the EPDS".

scientific article

Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10

scientific article published on 22 November 2013

Risk of postmenopausal hormone therapy and patient history factors for the survival rate in women with endometrial carcinoma

scientific article published on 19 December 2019

Shared decision-making in metastatic breast cancer: discrepancy between the expected prolongation of life and treatment efficacy between patients and physicians, and influencing factors

scientific article published on 14 May 2013

Shared genetics underlying epidemiological association between endometriosis and ovarian cancer

scientific article published on 30 July 2015

Socioeconomic status and depression during and after pregnancy in the Franconian Maternal Health Evaluation Studies (FRAMES).

scientific article published on 12 October 2013

TILGen: A Program to Investigate Immune Targets in Breast Cancer Patients - First Results on the Influence of Tumor-Infiltrating Lymphocytes

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

scientific article published on 01 November 2019

The PI3K Pathway: Background and Treatment Approaches

scientific article published on 8 December 2016

The UGT1A6_19_GG genotype is a breast cancer risk factor

scientific article published on 11 June 2013

Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system

scientific article published on 24 October 2011

Two truncating variants in FANCC and breast cancer risk

scientific article published on 29 August 2019

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility

scientific article published in PLoS ONE

Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer

scientific article published on 16 April 2014

p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article published on 22 March 2023

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology

scientific article published on 21 August 2018

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