List of works - Ivan C Moura

A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients

A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients.

scientific article published on 30 October 2003

An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia

scientific article

Balance between the two kinin receptors in the progression of experimental focal and segmental glomerulosclerosis in mice

scientific article

Both IgA nephropathy and alcoholic cirrhosis feature abnormally glycosylated IgA1 and soluble CD89-IgA and IgG-IgA complexes: common mechanisms for distinct diseases.

scientific article

Bradykinin receptor 1 activation exacerbates experimental focal and segmental glomerulosclerosis

scientific article published on 16 March 2011

Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

scientific article published on 20 May 2015

Correction: The Phospholipid Scramblases 1 and 4 Are Cellular Receptors for the Secretory Leukocyte Protease Inhibitor and Interact with CD4 at the Plasma Membrane

scientific article

Deferasirox and vitamin D improves overall survival in elderly patients with acute myeloid leukemia after demethylating agents failure

scientific article

Engagement of Transferrin Receptor by Polymeric IgA1: Evidence for a Positive Feedback Loop Involving Increased Receptor Expression and Mesangial Cell Proliferation in IgA Nephropathy

article

Enhanced Expression of the CD71 Mesangial IgA1 Receptor in Berger Disease and Henoch-Schonlein Nephritis: Association between CD71 Expression and IgA Deposits

scientific article published on 01 February 2003

Erythroferrone: the missing link in β-thalassemia?

scientific article

Erythropoiesis and transferrin receptors

scientific article published on May 2015

Evidence for mast cells contributing to neuromuscular pathology in an inherited model of ALS.

scientific article published on 19 October 2017

Fcα receptor I activation induces leukocyte recruitment and promotes aggravation of glomerulonephritis through the FcRγ adaptor

scientific article published on 01 April 2007

Genetic immunization of BALB/c mice with a plasmid bearing the gene coding for a hybrid merozoite surface protein 1-hepatitis B virus surface protein fusion protects mice against lethal Plasmodium chabaudi chabaudi PC1 infection

scientific article

Gluten induces coeliac-like disease in sensitised mice involving IgA, CD71 and transglutaminase 2 interactions that are prevented by probiotics

scientific article published on 13 February 2012

HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia

scientific article

Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1

scientific article

Human CD4- invariant NKT lymphocytes regulate graft versus host disease

scientific article published on 23 August 2018

Human erythroleukemia: is the two-hit model of mouse leukemogenesis valid in human disease?

scientific article published on 31 May 2007

Immunoglobuline A1

scientific article published on 22 August 2012

Immunosuppressive role of semaphorin-3A on T cell proliferation is mediated by inhibition of actin cytoskeleton reorganization

scientific article published on 01 July 2006

Ineffective erythropoiesis in β -thalassemia

scientific article

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

scientific article published on 06 September 2013

Interactions among secretory immunoglobulin A, CD71, and transglutaminase-2 affect permeability of intestinal epithelial cells to gliadin peptides

scientific article

Limonene arrests parasite development and inhibits isoprenylation of proteins in Plasmodium falciparum.

scientific article

Mast cells and neutrophils mediate peripheral motor pathway degeneration in ALS

scientific article published on 04 October 2018

Mucosal-associated invariant T (MAIT) cells: an evolutionarily conserved T cell subset

scientific article

NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells

New insights into the pathogenesis of IgA nephropathy

scientific article published on 18 January 2014

Novel players in β-thalassemia dyserythropoiesis and new therapeutic strategies

scientific article

Pathogénie de la maladie de Berger : implication des immunoglobulines A et de leurs récepteurs

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

scientific article

Plasmodium chabaudi chabaudi: a monoclonal antibody raised against soluble antigens present in the plasma of infected mice recognizes a 250-kDa schizont glycoprotein that is secreted during schizogony.

scientific article

Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia

scientific article published on 23 October 2011

Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis

scientific article published on 11 July 2016

Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments

scientific article published on February 2007

Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis

scientific article

Recent advances in adult T-cell leukemia therapy: focus on a new anti-transferrin receptor monoclonal antibody

scientific article published on 27 September 2007

Regulation of the tyrosine phosphorylation of Phospholipid Scramblase 1 in mast cells that are stimulated through the high-affinity IgE receptor

scientific article

Secretory IgA induces tolerogenic dendritic cells through SIGNR1 dampening autoimmunity in mice.

scientific article published on 7 August 2013

Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease

scientific article

Stepwise development of MAIT cells in mouse and human

scientific article

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

scientific article

Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

scientific article

Targeting oxidative metabolism to treat leukemia?

scientific article published in December 2010

The IgA1 immune complex–mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy ⬇️

scientific article published on 05 September 2012

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

scientific article published on 28 July 2010

The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells.

scientific article

The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.

scientific article published on 6 December 2011

The glomerular response to IgA deposition in IgA nephropathy.

scientific article published on January 2008

The lack of PI3Kγ favors M1 macrophage polarization and does not prevent kidney diseases progression

scholarly article by Mariane T. Amano et al published November 2018 in International Immunopharmacology

The phospholipid scramblases 1 and 4 are cellular receptors for the secretory leukocyte protease inhibitor and interact with CD4 at the plasma membrane

scientific article

The role of mast cells in cancers

scientific article

Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.

scientific article published on 26 March 2012

List of works by Ivan C Moura

A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients

A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients.

An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia

Balance between the two kinin receptors in the progression of experimental focal and segmental glomerulosclerosis in mice

Both IgA nephropathy and alcoholic cirrhosis feature abnormally glycosylated IgA1 and soluble CD89-IgA and IgG-IgA complexes: common mechanisms for distinct diseases.

Bradykinin receptor 1 activation exacerbates experimental focal and segmental glomerulosclerosis

Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

Correction: The Phospholipid Scramblases 1 and 4 Are Cellular Receptors for the Secretory Leukocyte Protease Inhibitor and Interact with CD4 at the Plasma Membrane

Deferasirox and vitamin D improves overall survival in elderly patients with acute myeloid leukemia after demethylating agents failure

Engagement of Transferrin Receptor by Polymeric IgA1: Evidence for a Positive Feedback Loop Involving Increased Receptor Expression and Mesangial Cell Proliferation in IgA Nephropathy

Enhanced Expression of the CD71 Mesangial IgA1 Receptor in Berger Disease and Henoch-Schonlein Nephritis: Association between CD71 Expression and IgA Deposits

Erythroferrone: the missing link in β-thalassemia?

Erythropoiesis and transferrin receptors

Evidence for mast cells contributing to neuromuscular pathology in an inherited model of ALS.

Fcα receptor I activation induces leukocyte recruitment and promotes aggravation of glomerulonephritis through the FcRγ adaptor

Genetic immunization of BALB/c mice with a plasmid bearing the gene coding for a hybrid merozoite surface protein 1-hepatitis B virus surface protein fusion protects mice against lethal Plasmodium chabaudi chabaudi PC1 infection

Gluten induces coeliac-like disease in sensitised mice involving IgA, CD71 and transglutaminase 2 interactions that are prevented by probiotics

HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia

Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1

Human CD4- invariant NKT lymphocytes regulate graft versus host disease

Human erythroleukemia: is the two-hit model of mouse leukemogenesis valid in human disease?

Immunoglobuline A1

Immunosuppressive role of semaphorin-3A on T cell proliferation is mediated by inhibition of actin cytoskeleton reorganization

Ineffective erythropoiesis in β -thalassemia

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

Interactions among secretory immunoglobulin A, CD71, and transglutaminase-2 affect permeability of intestinal epithelial cells to gliadin peptides

Limonene arrests parasite development and inhibits isoprenylation of proteins in Plasmodium falciparum.

Mast cells and neutrophils mediate peripheral motor pathway degeneration in ALS

Mucosal-associated invariant T (MAIT) cells: an evolutionarily conserved T cell subset

NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells

New insights into the pathogenesis of IgA nephropathy

Novel players in β-thalassemia dyserythropoiesis and new therapeutic strategies

Pathogénie de la maladie de Berger : implication des immunoglobulines A et de leurs récepteurs

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

Plasmodium chabaudi chabaudi: a monoclonal antibody raised against soluble antigens present in the plasma of infected mice recognizes a 250-kDa schizont glycoprotein that is secreted during schizogony.

Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia

Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis

Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments

Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis

Recent advances in adult T-cell leukemia therapy: focus on a new anti-transferrin receptor monoclonal antibody

Regulation of the tyrosine phosphorylation of Phospholipid Scramblase 1 in mast cells that are stimulated through the high-affinity IgE receptor

Secretory IgA induces tolerogenic dendritic cells through SIGNR1 dampening autoimmunity in mice.

Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease

Stepwise development of MAIT cells in mouse and human

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

Targeting oxidative metabolism to treat leukemia?

The IgA1 immune complex–mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy ⬇️

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells.

The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.

The glomerular response to IgA deposition in IgA nephropathy.

The lack of PI3Kγ favors M1 macrophage polarization and does not prevent kidney diseases progression

The phospholipid scramblases 1 and 4 are cellular receptors for the secretory leukocyte protease inhibitor and interact with CD4 at the plasma membrane

The role of mast cells in cancers

Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.