List of works - Katja Steiger

A Novel Approach for Image-Guided 131I Therapy of Pancreatic Ductal Adenocarcinoma Using Mesenchymal Stem Cell-Mediated NIS Gene Delivery

scientific article published on 17 September 2018

A Novel Grading System Based on Tumor Budding and Cell Nest Size Is a Strong Predictor of Patient Outcome in Esophageal Squamous Cell Carcinoma

scientific article published on 12 May 2017

A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer

scientific article published on 8 December 2014

A critical role for Akt1 signaling in acute pancreatitis progression†

scientific article published on 31 January 2020

A porcine model of osteosarcoma

scientific article published on 14 March 2016

Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells

scientific article published on 19 May 2016

Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin

scientific article published on 15 October 2020

Antifibrotic properties of transarterial oncolytic VSV therapy for hepatocellular carcinoma in rats with thioacetamide-induced liver fibrosis.

scientific article published on 13 August 2013

Apparent Diffusion Coefficient (ADC) predicts therapy response in pancreatic ductal adenocarcinoma

scientific article published on 6 December 2017

Appendiceal goblet cell carcinoids and adenocarcinomas ex-goblet cell carcinoid are genetically distinct from primary colorectal-type adenocarcinoma of the appendix

scientific article published on 12 January 2018

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

scientific article

CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness

scientific article published on 06 August 2021

Chronic Pancreatitis with Acinar–Ductal Metaplasia and Ductal Dysplasia in a Horse

scientific article published in August 2015

Clinical and Pathological Data of 17 Non-Epithelial Pancreatic Tumors in Cats

scientific article published on 27 April 2020

Co-clinical Assessment of Tumor Cellularity in Pancreatic Cancer

scientific article published on 23 September 2016

Combined Inhibition of Epigenetic Readers and Transcription Initiation Targets the EWS-ETS Transcriptional Program in Ewing Sarcoma

scientific article published on 28 January 2020

Complementary, Selective PET Imaging of Integrin Subtypes α5β1 and αvβ3 Using 68Ga-Aquibeprin and 68Ga-Avebetrin.

scientific article published on 3 December 2015

Cytosolic nucleic acid sensors of the innate immune system promote liver regeneration after partial hepatectomy

scientific article published in Scientific Reports

DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma

scientific article published on 30 November 2012

Detection of equine herpesvirus-1 in the fetal membranes of aborted equine fetuses by immunohistochemical and in-situ hybridization techniques

scientific article published on 01 August 2003

First In-Human Medical Imaging with a PASylated 89Zr-Labeled Anti-HER2 Fab-Fragment in a Patient with Metastatic Breast Cancer

scientific article published on 20 April 2020

Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer

scientific article published on 01 December 2021

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma

scientific article published on 12 January 2022

Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions

scientific article published on 13 August 2020

Glycemic Variability Promotes Both Local Invasion and Metastatic Colonization by Pancreatic Ductal Adenocarcinoma

scientific article published on 26 July 2018

Gut bacterial dysbiosis and instability is associated with the onset of complications and mortality in COVID-19

scientific article published on 01 January 2022

Helicobacter pylori γ-glutamyl transferase contributes to colonization and differential recruitment of T cells during persistence

scientific article published on 20 October 2017

Image-Based Molecular Phenotyping of Pancreatic Ductal Adenocarcinoma

scientific article published on 07 March 2020

Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid

scientific article

Immuno-PET Imaging of Engineered Human T Cells in Tumors

scientific article published on 28 June 2016

Impact of Tumor Localization and Molecular Subtypes on the Prognostic and Predictive Significance of p53 Expression in Gastric Cancer

scientific article published on 25 June 2020

Integrin αvβ3-dependent thyroid hormone effects on tumour proliferation and vascularisation

scientific article published on 01 September 2020

Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice

scientific article published on 28 January 2020

Loss of Ifnar1 in Pancreatic Acinar Cells Ameliorates the Disease Course of Acute Pancreatitis

scientific article

Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis

scientific article published on 27 November 2015

MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically

scientific article published on 10 September 2020

Model Matters: Differences in Orthotopic Rat Hepatocellular Carcinoma Physiology Determine Therapy Response to Sorafenib

scientific article published on 20 May 2015

Modeling Therapy Response and Spatial Tissue Distribution of Erlotinib in Pancreatic Cancer

scientific article published on 28 January 2016

Molecular Genetic Investigation of Digital Melanoma in Dogs

scientific article published in 2022

Morphology of canine placental sites after induced embryonic or fetal death

scientific article published on 14 February 2006

Multiparametric Modelling of Survival in Pancreatic Ductal Adenocarcinoma Using Clinical, Histomorphological, Genetic and Image-Derived Parameters

scientific article published on 25 April 2020

Multiplexed imaging and automated signal quantification in formalin-fixed paraffin-embedded tissues by ChipCytometry

scientific article published on 27 October 2021

Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

scientific article

Mutation of the Cell Cycle Regulator p27kip1 Drives Pseudohypoxic Pheochromocytoma Development

scientific article published on 02 January 2021

NRG1 Fusions in KRAS Wild-type Pancreatic Cancer.

scientific article

Neuroendocrine Differentiation in Conventional Colorectal Adenocarcinomas: Incidental Finding or Prognostic Biomarker?

scientific article published in 2021

Nociception-Induced Changes in Electroencephalographic Activity and FOS Protein Expression in Piglets Undergoing Castration under Isoflurane Anaesthesia

scientific article published in 2022

PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue - prognostic implications and rationale for immunotherapy

scientific article published on 20 November 2017

PET imaging of oncolytic VSV expressing the mutant HSV-1 thymidine kinase transgene in a preclinical HCC rat model.

scientific article published on 22 January 2015

Pancreas-specific activation of mTOR and loss of p53 induce tumors reminiscent of acinar cell carcinoma

scientific article

Pathology, genetics and precursors of human and experimental pancreatic neoplasms: An update

scientific article published on 03 September 2015

Periostin promotes pancreatic carcinogenesis and metastatic spread

scholarly article by Simone Hausmann et al published June 2015 in Pancreatology

PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice

scientific article published on 29 March 2019

Probing lactate secretion in tumours with hyperpolarised NMR.

scientific article published on 27 June 2016

Quantification of Endothelial αvβ3 Expression with High-Frequency Ultrasound and Targeted Microbubbles: In Vitro and In Vivo Studies

scientific article published on 11 June 2016

RIG-I activation is critical for responsiveness to checkpoint blockade

scientific article published on 01 September 2019

Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell-Mediated Sodium Iodide Symporter (NIS) Gene 131I Therapy

scientific article published on 13 June 2019

Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment

scientific article published on 31 January 2022

Several genotypes, one phenotype: PIK3CA/AKT1 mutation-negative hidradenoma papilliferum show genetic lesions in other components of the signalling network

scientific article published on 19 April 2019

Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection

scientific article published on 25 July 2019

Systemic antitumor effect by regional hyperthermia combined with low-dose chemotherapy and immunologic correlates in an adolescent patient with rhabdomyosarcoma - a case report

scientific article published on 01 January 2020

Targeted positron emission tomography imaging of CXCR4 expression in patients with acute myeloid leukemia

scientific article published on 12 May 2016

Toxicity of a combined therapy using the mTOR-inhibitor everolimus and PRRT with [177Lu]Lu-DOTA-TATE in Lewis rats

scientific article published on 25 April 2020

Tumour budding activity and cell nest size determine patient outcome in oral squamous cell carcinoma: proposal for an adjusted grading system

scientific article published on 25 January 2017

Uncommon mycobacterial infections in domestic and zoo animals: four cases with special emphasis on pathology

scientific article published on September 1, 2003

Variation of Specific Activities of 68Ga-Aquibeprin and 68Ga-Avebetrin Enables Selective PET Imaging of Different Expression Levels of Integrins α5β1 and αvβ3.

scientific article published on 5 May 2016

List of works by Katja Steiger

A Novel Approach for Image-Guided 131I Therapy of Pancreatic Ductal Adenocarcinoma Using Mesenchymal Stem Cell-Mediated NIS Gene Delivery

A Novel Grading System Based on Tumor Budding and Cell Nest Size Is a Strong Predictor of Patient Outcome in Esophageal Squamous Cell Carcinoma

A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer

A critical role for Akt1 signaling in acute pancreatitis progression†

A porcine model of osteosarcoma

Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells

Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin

Antifibrotic properties of transarterial oncolytic VSV therapy for hepatocellular carcinoma in rats with thioacetamide-induced liver fibrosis.

Apparent Diffusion Coefficient (ADC) predicts therapy response in pancreatic ductal adenocarcinoma

Appendiceal goblet cell carcinoids and adenocarcinomas ex-goblet cell carcinoid are genetically distinct from primary colorectal-type adenocarcinoma of the appendix

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness

Chronic Pancreatitis with Acinar–Ductal Metaplasia and Ductal Dysplasia in a Horse

Clinical and Pathological Data of 17 Non-Epithelial Pancreatic Tumors in Cats

Co-clinical Assessment of Tumor Cellularity in Pancreatic Cancer

Combined Inhibition of Epigenetic Readers and Transcription Initiation Targets the EWS-ETS Transcriptional Program in Ewing Sarcoma

Complementary, Selective PET Imaging of Integrin Subtypes α5β1 and αvβ3 Using 68Ga-Aquibeprin and 68Ga-Avebetrin.

Cytosolic nucleic acid sensors of the innate immune system promote liver regeneration after partial hepatectomy

DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma

Detection of equine herpesvirus-1 in the fetal membranes of aborted equine fetuses by immunohistochemical and in-situ hybridization techniques

First In-Human Medical Imaging with a PASylated 89Zr-Labeled Anti-HER2 Fab-Fragment in a Patient with Metastatic Breast Cancer

Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma

Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions

Glycemic Variability Promotes Both Local Invasion and Metastatic Colonization by Pancreatic Ductal Adenocarcinoma

Gut bacterial dysbiosis and instability is associated with the onset of complications and mortality in COVID-19

Helicobacter pylori γ-glutamyl transferase contributes to colonization and differential recruitment of T cells during persistence

Image-Based Molecular Phenotyping of Pancreatic Ductal Adenocarcinoma

Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid

Immuno-PET Imaging of Engineered Human T Cells in Tumors

Impact of Tumor Localization and Molecular Subtypes on the Prognostic and Predictive Significance of p53 Expression in Gastric Cancer

Integrin αvβ3-dependent thyroid hormone effects on tumour proliferation and vascularisation

Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice

Loss of Ifnar1 in Pancreatic Acinar Cells Ameliorates the Disease Course of Acute Pancreatitis

Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis

MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically

Model Matters: Differences in Orthotopic Rat Hepatocellular Carcinoma Physiology Determine Therapy Response to Sorafenib

Modeling Therapy Response and Spatial Tissue Distribution of Erlotinib in Pancreatic Cancer

Molecular Genetic Investigation of Digital Melanoma in Dogs

Morphology of canine placental sites after induced embryonic or fetal death

Multiparametric Modelling of Survival in Pancreatic Ductal Adenocarcinoma Using Clinical, Histomorphological, Genetic and Image-Derived Parameters

Multiplexed imaging and automated signal quantification in formalin-fixed paraffin-embedded tissues by ChipCytometry

Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

Mutation of the Cell Cycle Regulator p27kip1 Drives Pseudohypoxic Pheochromocytoma Development

NRG1 Fusions in KRAS Wild-type Pancreatic Cancer.

Neuroendocrine Differentiation in Conventional Colorectal Adenocarcinomas: Incidental Finding or Prognostic Biomarker?

Nociception-Induced Changes in Electroencephalographic Activity and FOS Protein Expression in Piglets Undergoing Castration under Isoflurane Anaesthesia

PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue - prognostic implications and rationale for immunotherapy

PET imaging of oncolytic VSV expressing the mutant HSV-1 thymidine kinase transgene in a preclinical HCC rat model.

Pancreas-specific activation of mTOR and loss of p53 induce tumors reminiscent of acinar cell carcinoma

Pathology, genetics and precursors of human and experimental pancreatic neoplasms: An update

Periostin promotes pancreatic carcinogenesis and metastatic spread

PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice

Probing lactate secretion in tumours with hyperpolarised NMR.

Quantification of Endothelial αvβ3 Expression with High-Frequency Ultrasound and Targeted Microbubbles: In Vitro and In Vivo Studies

RIG-I activation is critical for responsiveness to checkpoint blockade

Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell-Mediated Sodium Iodide Symporter (NIS) Gene 131I Therapy

Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment

Several genotypes, one phenotype: PIK3CA/AKT1 mutation-negative hidradenoma papilliferum show genetic lesions in other components of the signalling network

Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection

Systemic antitumor effect by regional hyperthermia combined with low-dose chemotherapy and immunologic correlates in an adolescent patient with rhabdomyosarcoma - a case report

Targeted positron emission tomography imaging of CXCR4 expression in patients with acute myeloid leukemia

Toxicity of a combined therapy using the mTOR-inhibitor everolimus and PRRT with [177Lu]Lu-DOTA-TATE in Lewis rats

Tumour budding activity and cell nest size determine patient outcome in oral squamous cell carcinoma: proposal for an adjusted grading system

Uncommon mycobacterial infections in domestic and zoo animals: four cases with special emphasis on pathology

Variation of Specific Activities of 68Ga-Aquibeprin and 68Ga-Avebetrin Enables Selective PET Imaging of Different Expression Levels of Integrins α5β1 and αvβ3.