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List of works by Abdelbasset A. Farahat

4-Dimethyl-amino-1-(4-meth-oxy-phen-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile

scientific article published on 23 February 2013

A modular design for minor groove binding and recognition of mixed base pair sequences of DNA.

scientific article

Antileishmanial bis-arylimidamides: DB766 analogs modified in the linker region and bis-arylimidamide structure-activity relationships.

scientific article published on 16 June 2012

Bichalcophenes: A Concise Synthesis of Formyl Ester- and Cyano Ester-Substituted Bithiophenes, Bifurans, and Furanothiophenes.

scientific article published on January 2010

DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site

scientific article published on 14 August 2010

Dynamic self-assembly of DNA minor groove-binding ligand DB921 into nanotubes triggered by an alkali halide.

scientific article

Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: in vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies

scientific article

Exploration of DAPI analogues: Synthesis, antitrypanosomal activity, DNA binding and fluorescence properties

scientific article published on 24 January 2017

Exploration of larger central ring linkers in furamidine analogues: synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties

scientific article

Heterocyclic dications as a new class of telomeric G-quadruplex targeting agents

scientific article published on January 2012

In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infection

scientific article

In vitro investigation of the efficacy of novel diamidines against Trypanosoma cruzi.

scientific article published on 15 April 2014

Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity

scientific article

Induced topological changes in DNA complexes: influence of DNA sequences and small molecule structures. ⬇️

scientific article

Investigation of the electrostatic and hydration properties of DNA minor groove-binding by a heterocyclic diamidine by osmotic pressure.

scientific article published on 20 March 2017

Pharmacologic efficacy of PU.1 inhibition by heterocyclic dications: a mechanistic analysis

scientific article published on 13 April 2016

Phenotypic Screening In Vitro of Novel Aromatic Amidines against Trypanosoma cruzi

scientific article published on 23 May 2016

Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

scientific article

Resolution of mixed site DNA complexes with dimer-forming minor-groove binders by using electrospray ionization mass spectrometry: compound structure and DNA sequence effects

scientific article published on 20 February 2015

SUZUKI-MIYAURA COUPLING REACTIONS OF 3,5-DICHLORO-1,2,4-THIADIAZOLE.

scientific article published on August 2012

Small Sequence-Sensitive Compounds for Specific Recognition of the G⋅C Base Pair in DNA Minor Groove

scientific article published on 13 March 2020

Structure-dependent binding of arylimidamides to the DNA minor groove

scientific article published on 9 December 2013

Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines

scientific article published on 23 October 2013

Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles

scientific article published on 27 March 2010

Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents

scientific article published on 25 March 2016

Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides

scientific article

Synthesis, DNA binding and antitrypanosomal activity of benzimidazole analogues of DAPI.

scientific article published on 3 November 2016

Synthesis, DNA binding, fluorescence measurements and antiparasitic activity of DAPI related diamidines

scientific article published on 11 December 2009

Synthesis, molecular modeling and anticancer activity of new coumarin containing compounds.

scientific article published on 10 February 2017

Systematic synthetic and biophysical development of mixed sequence DNA binding agents.

scientific article

Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

scientific journal article

The Thiophene "Sigma-Hole" as a Concept for Preorganized, Specific Recognition of G⋅C Base Pairs in the DNA Minor Groove

scientific article published on 14 September 2016

The efficacy of novel arylimidamides against Trypanosoma cruzi in vitro

scientific article published on 09 September 2011

The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA

scientific article

The unusual monomer recognition of guanine-containing mixed sequence DNA by a dithiophene heterocyclic diamidine

scientific article published on 13 February 2014

Water-mediated binding of agents that target the DNA minor groove

scientific article

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