List of works - Kondwani C Jambo

A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi

scientific article published on 24 August 2017

A platform for cardiovascular disease (CVD) research in Malawi, with an initial focus on the link between infection, vascular damage and hypertension ???? (Preprint)

A pneumococcal controlled human infection model in Malawi: Transfer of an established pneumococcal carriage model from Liverpool, UK to Blantyre, Malawi - A feasibility study

scientific article published on 14 April 2020

AIDS patients have increased surfactant protein D but normal mannose binding lectin levels in lung fluid

scientific article published on 13 June 2007

Airway CD8+CD161++TCRvα7.2+ T Cell Depletion During Untreated HIV Infection Targets CD103 Expressing Cells

scientific article published on 21 August 2019

Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults

scientific article published on 29 November 2017

Asymptomatic HIV-infected individuals on antiretroviral therapy exhibit impaired lung CD4(+) T-cell responses to mycobacteria

scientific article

B cell, CD8 + T cell and gamma delta T cell lymphocytic alveolitis alters alveolar immune cell homeostasis in HIV-infected Malawian adults.

scientific article published on 27 October 2017

Bronchoalveolar CD4+ T cell responses to respiratory antigens are impaired in HIV-infected adults

scientific article

Circulating microparticles are increased amongst people presenting with HIV and advanced immune suppression in Malawi and correlate closely with arterial stiffness: a nested case control study

scientific article published in 2022

Comparative whole genome analysis reveals re-emergence of human Wa-like and DS-1-like G3 rotaviruses after Rotarix vaccine introduction in Malawi

scientific article published in 2023

Delayed acquisition of Plasmodium falciparum antigen-specific CD4(+) T cell responses in HIV-exposed uninfected Malawian children receiving daily cotrimoxazole prophylaxis

scientific article published on 10 May 2016

Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa

scientific article published on 11 June 2021

Domestic smoke exposure is associated with alveolar macrophage particulate load

scientific article published on March 2009

Evaluating the reactivation of herpesviruses and inflammation as cardiovascular and cerebrovascular risk factors in antiretroviral therapy initiators in an African HIV-infected population (RHICCA): a protocol for a longitudinal cohort study

scientific article published on 12 September 2019

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease

scientific article published on 11 August 2020

Experimental human pneumococcal carriage augments IL-17A-dependent T-cell defence of the lung

scientific article

Experimental human pneumococcal carriage models for vaccine research

scientific article published on 23 July 2011

Functional Analysis of Phagocyte Activity in Whole Blood from HIV/Tuberculosis-Infected Individuals Using a Novel Flow Cytometry-Based Assay

scientific article published on 28 September 2017

HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy

scientific article published in October 2017

HIV-related arterial stiffness in Malawian adults is associated with proportion of PD-1 expressing CD8 T-cells and reverses with anti-retroviral therapy

article

Heterogeneous loss of HIV transcription and proviral DNA from 8E5/LAV lymphoblastic leukemia cells revealed by RNA FISH:FLOW analyses.

scientific article published on 11 August 2016

High SARS-CoV-2 seroprevalence in Health Care Workers but relatively low numbers of deaths in urban Malawi

scientific article published on 01 August 2020

Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.

scientific article published on 18 April 2018

Human nasal challenge with Streptococcus pneumoniae is immunising in the absence of carriage

scientific article

I have funds to buy reagents, but not remedies

scientific article published on 22 June 2022

Impaired CD4 T cell memory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults

scientific article

Implementation of Antibody Rapid Diagnostic Testing versus Real-Time Reverse Transcription-PCR Sample Pooling in the Screening of COVID-19: a Case of Different Testing Strategies in Africa

scientific article published on 29 July 2020

Incomplete recovery of pneumococcal CD4 T cell immunity after initiation of antiretroviral therapy in HIV-infected malawian adults

scientific article

Inflammatory Phenotypes Predict Changes in Arterial Stiffness following ART Initiation

scientific article published on 27 February 2020

Influenza-like illness is associated with high pneumococcal carriage density in Malawian children

scientific article published on 22 July 2020

Inhaled delivery of 23-valent pneumococcal polysaccharide vaccine does not result in enhanced pulmonary mucosal immunoglobulin responses

scientific article published on 15 August 2008

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1-infected human macrophages

article

Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis

scientific article published on 28 May 2015

Latent tuberculosis infection among adults attending HIV services at an urban tertiary hospital in Malawi

scientific article published in 2022

Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children ⬇️

scientific article published on 17 May 2017

Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens

scientific article published on 01 February 2020

Naturally-acquired influenza-specific CD4+ T-cell proliferative responses are impaired in HIV-infected African adults

scientific article

New management approaches to tuberculosis in people living with HIV

scientific article published on 10 December 2020

Omicron B.1.1.529 variant infections associated with severe disease are uncommon in a COVID-19 under-vaccinated, high SARS-CoV-2 seroprevalence population in Malawi

scientific article published in 2023

Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4+ and CD8+ T Cells at the Human Intestinal Mucosa

scientific article published on 24 January 2016

Particulate Load From Biomass Smoke Is Associated With Increased Oxidative Burst And Reduced Proteolysis in Alveolar Macrophages

scientific article published in May 2010

Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000-2019: protocol for systematic review

scientific article published on 13 November 2019

Potential role for mucosally active vaccines against pneumococcal pneumonia

scientific article

Presence of MBL in airways: is it a disease severity marker or an additional host defence mechanism?

scientific article published on 01 September 2009

Proportions of CD4+, CD8+ and B cell subsets are not affected by exposure to HIV or to Cotrimoxazole prophylaxis in Malawian HIV-uninfected but exposed children.

scientific article published on 28 August 2015

Risk factors for pneumococcal carriage in adults living with HIV on antiretroviral therapy in the infant pneumococcal vaccine era in Malawi

scientific article published in 2022

SARS-CoV-2 Infection in Pregnant Women and Their Newborns

scientific article published on 08 October 2020

Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung

scientific article published on 22 July 2021

Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function

scientific article

Social mixing patterns relevant to infectious diseases spread by close contact in urban Blantyre, Malawi

scientific article published in 2022

Stakeholder views on the acceptability of human infection studies in Malawi

scientific article published on 05 February 2020

TZM-gfp cells: a tractable fluorescent tool for analysis of rare and early HIV-1 infection

scientific article published on 16 November 2020

The effect of daily co-trimoxazole prophylaxis on natural development of antibody-mediated immunity against P. falciparum malaria infection in HIV-exposed uninfected Malawian children

scientific article

“At first, I was very afraid”—a qualitative description of participants’ views and experiences in the first Human Infection Study in Malawi

scientific article published in 2021

List of works by Kondwani C Jambo

A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi

A platform for cardiovascular disease (CVD) research in Malawi, with an initial focus on the link between infection, vascular damage and hypertension ???? (Preprint)

A pneumococcal controlled human infection model in Malawi: Transfer of an established pneumococcal carriage model from Liverpool, UK to Blantyre, Malawi - A feasibility study

AIDS patients have increased surfactant protein D but normal mannose binding lectin levels in lung fluid

Airway CD8+CD161++TCRvα7.2+ T Cell Depletion During Untreated HIV Infection Targets CD103 Expressing Cells

Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults

Asymptomatic HIV-infected individuals on antiretroviral therapy exhibit impaired lung CD4(+) T-cell responses to mycobacteria

B cell, CD8 + T cell and gamma delta T cell lymphocytic alveolitis alters alveolar immune cell homeostasis in HIV-infected Malawian adults.

Bronchoalveolar CD4+ T cell responses to respiratory antigens are impaired in HIV-infected adults

Circulating microparticles are increased amongst people presenting with HIV and advanced immune suppression in Malawi and correlate closely with arterial stiffness: a nested case control study

Comparative whole genome analysis reveals re-emergence of human Wa-like and DS-1-like G3 rotaviruses after Rotarix vaccine introduction in Malawi

Delayed acquisition of Plasmodium falciparum antigen-specific CD4(+) T cell responses in HIV-exposed uninfected Malawian children receiving daily cotrimoxazole prophylaxis

Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa

Domestic smoke exposure is associated with alveolar macrophage particulate load

Evaluating the reactivation of herpesviruses and inflammation as cardiovascular and cerebrovascular risk factors in antiretroviral therapy initiators in an African HIV-infected population (RHICCA): a protocol for a longitudinal cohort study

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease

Experimental human pneumococcal carriage augments IL-17A-dependent T-cell defence of the lung

Experimental human pneumococcal carriage models for vaccine research

Functional Analysis of Phagocyte Activity in Whole Blood from HIV/Tuberculosis-Infected Individuals Using a Novel Flow Cytometry-Based Assay

HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy

HIV-related arterial stiffness in Malawian adults is associated with proportion of PD-1 expressing CD8 T-cells and reverses with anti-retroviral therapy

Heterogeneous loss of HIV transcription and proviral DNA from 8E5/LAV lymphoblastic leukemia cells revealed by RNA FISH:FLOW analyses.

High SARS-CoV-2 seroprevalence in Health Care Workers but relatively low numbers of deaths in urban Malawi

Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.

Human nasal challenge with Streptococcus pneumoniae is immunising in the absence of carriage

I have funds to buy reagents, but not remedies

Impaired CD4 T cell memory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults

Implementation of Antibody Rapid Diagnostic Testing versus Real-Time Reverse Transcription-PCR Sample Pooling in the Screening of COVID-19: a Case of Different Testing Strategies in Africa

Incomplete recovery of pneumococcal CD4 T cell immunity after initiation of antiretroviral therapy in HIV-infected malawian adults

Inflammatory Phenotypes Predict Changes in Arterial Stiffness following ART Initiation

Influenza-like illness is associated with high pneumococcal carriage density in Malawian children

Inhaled delivery of 23-valent pneumococcal polysaccharide vaccine does not result in enhanced pulmonary mucosal immunoglobulin responses

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1-infected human macrophages

Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis

Latent tuberculosis infection among adults attending HIV services at an urban tertiary hospital in Malawi

Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children ⬇️

Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens

Naturally-acquired influenza-specific CD4+ T-cell proliferative responses are impaired in HIV-infected African adults

New management approaches to tuberculosis in people living with HIV

Omicron B.1.1.529 variant infections associated with severe disease are uncommon in a COVID-19 under-vaccinated, high SARS-CoV-2 seroprevalence population in Malawi

Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4+ and CD8+ T Cells at the Human Intestinal Mucosa

Particulate Load From Biomass Smoke Is Associated With Increased Oxidative Burst And Reduced Proteolysis in Alveolar Macrophages

Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000-2019: protocol for systematic review

Potential role for mucosally active vaccines against pneumococcal pneumonia

Presence of MBL in airways: is it a disease severity marker or an additional host defence mechanism?

Proportions of CD4+, CD8+ and B cell subsets are not affected by exposure to HIV or to Cotrimoxazole prophylaxis in Malawian HIV-uninfected but exposed children.

Risk factors for pneumococcal carriage in adults living with HIV on antiretroviral therapy in the infant pneumococcal vaccine era in Malawi

SARS-CoV-2 Infection in Pregnant Women and Their Newborns

Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung

Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function

Social mixing patterns relevant to infectious diseases spread by close contact in urban Blantyre, Malawi

Stakeholder views on the acceptability of human infection studies in Malawi

TZM-gfp cells: a tractable fluorescent tool for analysis of rare and early HIV-1 infection

The effect of daily co-trimoxazole prophylaxis on natural development of antibody-mediated immunity against P. falciparum malaria infection in HIV-exposed uninfected Malawian children

“At first, I was very afraid”—a qualitative description of participants’ views and experiences in the first Human Infection Study in Malawi