List of works by Utz Fischer

A 5'-fluorosulfonylbenzoyladenosine-based method to identify physiological substrates of a Drosophila p21-activated kinase.

scientific article published on 26 May 2007

A 69-kD protein that associates reversibly with the Sm core domain of several spliceosomal snRNP species.

scientific article published on February 1994

A comprehensive interaction map of the human survival of motor neuron (SMN) complex

scientific article published on 18 December 2006

A crystallization screen based on alternative polymeric precipitants

scientific article published on 15 May 2010

A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export

scientific article

Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes

scientific article

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

scientific article

An essential signaling role for the m3G cap in the transport of U1 snRNP to the nucleus

scientific article published on 01 August 1990

Analysis of genomic clones of the murine U1RNA-associated 70-kDa protein reveals a high evolutionary conservation of the protein between human and mouse

scientific article

Analysis of photoreceptor degeneration in the zebrafish Danio rerio

scientific article published on 01 January 2013

Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I.

scientific article

Assembly of RNPs: help needed.

scientific article published on April 2015

Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs

scientific article published on November 2002

Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression

scientific article

Biogenesis of spliceosomal small nuclear ribonucleoproteins

scientific article published on 25 April 2011

Cellular strategies for the assembly of molecular machines ⬇️

scientific article published on August 19, 2010

Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1)

scientific journal article

Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins

scientific article (publication date: 12 August 2000)

Chemical Synthesis of a 5'-Terminal TMG-Capped Triribonucleotide m(3)(2,2,7)G(5)(')pppAmpUmpA of U1 RNA

scientific article published on 01 June 1996

Co-regulation of survival of motor neuron (SMN) protein and its interactor SIP1 during development and in spinal muscular atrophy

scientific article (publication date: March 2001)

Crystallizing the 6S and 8S spliceosomal assembly intermediates: a complex project

scientific article published on 26 September 2015

Cytoplasmic gene expression: lessons from poxviruses

scientific article published in 2022

Deciphering the assembly pathway of Sm-class U snRNPs

scientific article published on 17 March 2008

Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

scientific article published on 04 August 2013

Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport

scientific article published on May 1991

Drug-Encoded Biomarkers for Monitoring Biological Therapies

scientific article

Epstein-Barr virus nuclear antigen 2 binds via its methylated arginine-glycine repeat to the survival motor neuron protein.

scientific article

Evidence that fragile X mental retardation protein is a negative regulator of translation

scientific journal article

Evolution of an RNP assembly system: a minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster

scholarly article

Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death

scientific article

HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import.

scientific article

Identification and structural analysis of the Schizosaccharomyces pombe SMN complex

scientific article published on 01 July 2021

Identification of a PRPF4 loss-of-function variant that abrogates U4/U6.U5 tri-snRNP integration and is associated with retinitis pigmentosa

scientific article

Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation

scientific article published on 21 June 2017

In vitro reconstitution of U1 and U2 snRNPs from isolated proteins and snRNA

scientific article published on 01 September 1992

Interaction of 7SK with the Smn complex modulates snRNP production

scientific article published on 24 February 2021

Intronic miR-26b controls neuronal differentiation by repressing its host transcript, ctdsp2

scientific article

LARP4B is an AU-rich sequence associated factor that promotes mRNA accumulation and translation

scientific article

LSm1-7 complexes bind to specific sites in viral RNA genomes and regulate their translation and replication.

scientific article

Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln

scientific article (publication date: 11 December 2001)

Molding Photonic Boxes into Fluorescent Emitters by Direct Laser Writing.

scientific article

Molecular and functional analysis of intragenic SMN1 mutations in patients with spinal muscular atrophy.

scientific article

Mutant Prpf31 causes pre-mRNA splicing defects and rod photoreceptor cell degeneration in a zebrafish model for Retinitis pigmentosa.

scientific article

Mutations in SNRPE, which encodes a core protein of the spliceosome, cause autosomal-dominant hypotrichosis simplex

scientific article

Nuclear transport of U1 snRNP in somatic cells: differences in signal requirement compared with Xenopus laevis oocytes

scientific article published on June 1994

Phosphoregulation of the human SMN complex

scientific article

Phosphorylation regulates the activity of the SMN complex during assembly of spliceosomal U snRNPs.

scientific article

ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space

scientific article (publication date: September 2015)

Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy

scientific article published on October 2005

Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle.

scientific article published on November 1999

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

scientific article published on 16 November 2010

Room temperature organic exciton-polariton condensate in a lattice

scientific article published on 08 June 2020

SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy

scientific article

SMN-mediated assembly of RNPs: a complex story

scientific journal article

SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome

scientific article

Signal-mediated nuclear export pathways of proteins and RNAs.

scientific article published in August 1996

Spinal muscular atrophy: the RNP connection

scientific article published on 13 February 2006

Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins

scientific article

Structural basis of assembly chaperone- mediated snRNP formation

scientific article

Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein.

scientific article

Systemic splicing factor deficiency causes tissue-specific defects: a zebrafish model for retinitis pigmentosa.

scientific article published on 3 November 2010

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

scientific article (publication date: 11 August 1995)

The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes

scientific article

The Ribosome Cooperates with the Assembly Chaperone pICln to Initiate Formation of snRNPs.

scientific article published in September 2016

The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis

scientific article

The Sm core domain mediates targeting of U1 snRNP to subnuclear compartments involved in transcription and splicing

scientific article published on 01 June 1999

The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization.

scientific article published on 12 November 2014

The role of RNP biogenesis in spinal muscular atrophy

scientific article published on 13 March 2009

The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins

scientific article

The structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic cooperativity

scientific article

Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes

scientific article

Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates

scientific article (publication date: 11 August 2009)

Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing

scientific article

Unrip, a factor implicated in cap-independent translation, associates with the cytosolic SMN complex and influences its intracellular localization

scientific article

Paulina is supported by:

About Paulina

Help