List of works - Jonathan S Wall

Thermodynamic instability of human lambda 6 light chains: correlation with fibrillogenicity

scientific article published on 01 October 1999

Antibody-mediated resolution of light chain-associated amyloid deposits.

scientific article published on October 2000

Chemical typing of amyloid protein contained in formalin-fixed paraffin-embedded biopsy specimens.

scientific article

Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice

scientific article published on August 22, 2012

In vivo molecular imaging of peripheral amyloidosis using heparin-binding peptides.

scientific article

Thermodynamic modulation of light chain amyloid fibril formation

scientific article published on 01 January 2000

Structural basis of light chain amyloidogenicity: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four Vlambda6 proteins.

scientific article

Gold coated lanthanide phosphate nanoparticles for targeted alpha generator radiotherapy

scientific article

AL amyloid imaging and therapy with a monoclonal antibody to a cryptic epitope on amyloid fibrils.

scientific article

Light chain-associated amyloid deposits comprised of a novel κ constant domain

scientific article published on August 4, 1998

The use of fluoresceinphosphatidylethanolamine (FPE) as a real-time probe for peptide-membrane interactions

scientific article published on 01 April 1995

Immunotherapy in systemic primary (AL) amyloidosis using amyloid-reactive monoclonal antibodies.

scientific article published on December 2003

The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease.

scientific article

In vitro immunoglobulin light chain fibrillogenesis

scientific article published on 01 January 1999

Diagnostic and therapeutic potential of amyloid-reactive IgG antibodies contained in human sera

scientific article published on 01 June 2006

Disruption of chromodomain helicase DNA binding protein 2 (CHD2) causes scoliosis.

scientific article published in May 2008

Foxn3 is essential for craniofacial development in mice and a putative candidate involved in human congenital craniofacial defects

scientific journal article

The fate of MAb-targeted Cd(125m)Te/ZnS nanoparticles in vivo.

scientific article published on 3 April 2008

Human plasma contains cross-reactive Abeta conformer-specific IgG antibodies

scientific article published on 01 November 2008

A Routine PET/CT Protocol with Streamlined Calculations for Assessing Cardiac Amyloidosis Using (18)F-Florbetapir.

scientific article published on 8 May 2015

Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes

scientific article published on 22 September 2015

Cell Damage in Light Chain Amyloidosis: FIBRIL INTERNALIZATION, TOXICITY AND CELL-MEDIATED SEEDING.

scientific article published on 26 July 2016

Micro-imaging of amyloid in mice.

scientific article published on January 2006

Localization of a conformational epitope common to non-native and fibrillar immunoglobulin light chains.

scientific article published on February 2007

Comparative Analysis of Peptide p5 and Serum Amyloid P Component for Imaging AA Amyloid in Mice Using Dual-Isotope SPECT

scientific article published on August 1, 2012

Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake.

scientific article

Interim analysis of the phase 1a/b study of chimeric fibril-reactive monoclonal antibody 11-1F4 in patients with AL amyloidosis

article

Preclinical Validation of the Heparin-Reactive Peptide p5+14 as a Molecular Imaging Agent for Visceral Amyloidosis

scientific article published on 27 April 2015

Quantitative tomography of early-onset spontaneous AA amyloidosis in interleukin 6 transgenic mice

scientific article published on December 2008

Peptide p5 binds both heparinase-sensitive glycosaminoglycans and fibrils in patient-derived AL amyloid extracts

scientific article published on May 23, 2013

Quantitative high-resolution microradiographic imaging of amyloid deposits in a novel murine model of AA amyloidosis

scientific article published in September 2005

Radioimaging of light chain amyloid with a fibril-reactive monoclonal antibody

scientific article published on December 2006

Therapeutic potential of chimeric amyloid-reactive monoclonal antibody 11-1F4.

scientific article published in September 2003

A binding-site barrier affects imaging efficiency of high affinity amyloid-reactive peptide radiotracers in vivo

scientific article

Phage display and peptide mapping of an immunoglobulin light chain fibril-related conformational epitope

scientific article

LnPO4 nanoparticles doped with Ac-225 and sequestered daughters for targeted alpha therapy

scientific article published on 08 October 2013

Immunodiagnostic capabilities of anti-free immunoglobulin light chain monoclonal antibodies

scientific article

Dynamic PET and SPECT imaging with radioiodinated, amyloid-reactive peptide p5 in mice: a positive role for peptide dehalogenation.

scientific article

Comparative evaluation of p5+14 with SAP and peptide p5 by dual-energy SPECT imaging of mice with AA amyloidosis.

scientific article published on 3 March 2016

Phagocyte depletion inhibits AA amyloid accumulation in AEF-induced huIL-6 transgenic mice

scientific article

Preliminary evaluation of serial (18) FDG-PET/CT to assess response to toceranib phosphate therapy in canine cancer.

scientific article published on 24 February 2012

Characterization of X-ray Dose in Murine Animals Using microCT, a New Low-Dose Detector and nanoDot Dosimeters

scientific article

ODAM Expression Inhibits Human Breast Cancer Tumorigenesis.

scientific article

Immunoglobulin Light Chains Form an Extensive and Highly Ordered Fibril Involving the N- and C-Termini.

scientific article published on 27 February 2017

The N-terminal strand modulates immunoglobulin light chain fibrillogenesis.

scientific article published on 7 December 2013

Secondary structure propensity and chirality of the amyloidophilic peptide p5 and its analogues impacts ligand binding - In vitro characterization

scientific article published on 11 August 2016

Novel heparan sulfate-binding peptides for blocking herpesvirus entry.

scientific article published on 18 May 2015

A novel method for quantifying peripheral tissue amyloid load by using the radiolabeled amyloidophilic peptide, p5

scientific article published on January 17, 2013

SPECT imaging of peripheral amyloid in mice by targeting hyper-sulfated heparan sulfate proteoglycans with specific scFv antibodies.

scientific article published on 29 September 2011

Guidance for Methods Descriptions Used in Preclinical Imaging Papers

scientific article published on October 1, 2013

List of works by Jonathan S Wall

Thermodynamic instability of human lambda 6 light chains: correlation with fibrillogenicity

Antibody-mediated resolution of light chain-associated amyloid deposits.

Chemical typing of amyloid protein contained in formalin-fixed paraffin-embedded biopsy specimens.

Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice

In vivo molecular imaging of peripheral amyloidosis using heparin-binding peptides.

Thermodynamic modulation of light chain amyloid fibril formation

Structural basis of light chain amyloidogenicity: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four Vlambda6 proteins.

Gold coated lanthanide phosphate nanoparticles for targeted alpha generator radiotherapy

AL amyloid imaging and therapy with a monoclonal antibody to a cryptic epitope on amyloid fibrils.

Light chain-associated amyloid deposits comprised of a novel κ constant domain

The use of fluoresceinphosphatidylethanolamine (FPE) as a real-time probe for peptide-membrane interactions

Immunotherapy in systemic primary (AL) amyloidosis using amyloid-reactive monoclonal antibodies.

The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease.

In vitro immunoglobulin light chain fibrillogenesis

Diagnostic and therapeutic potential of amyloid-reactive IgG antibodies contained in human sera

Disruption of chromodomain helicase DNA binding protein 2 (CHD2) causes scoliosis.

Foxn3 is essential for craniofacial development in mice and a putative candidate involved in human congenital craniofacial defects

The fate of MAb-targeted Cd(125m)Te/ZnS nanoparticles in vivo.

Human plasma contains cross-reactive Abeta conformer-specific IgG antibodies

A Routine PET/CT Protocol with Streamlined Calculations for Assessing Cardiac Amyloidosis Using (18)F-Florbetapir.

Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes

Cell Damage in Light Chain Amyloidosis: FIBRIL INTERNALIZATION, TOXICITY AND CELL-MEDIATED SEEDING.

Micro-imaging of amyloid in mice.

Localization of a conformational epitope common to non-native and fibrillar immunoglobulin light chains.

Comparative Analysis of Peptide p5 and Serum Amyloid P Component for Imaging AA Amyloid in Mice Using Dual-Isotope SPECT

Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake.

Interim analysis of the phase 1a/b study of chimeric fibril-reactive monoclonal antibody 11-1F4 in patients with AL amyloidosis

Preclinical Validation of the Heparin-Reactive Peptide p5+14 as a Molecular Imaging Agent for Visceral Amyloidosis

Quantitative tomography of early-onset spontaneous AA amyloidosis in interleukin 6 transgenic mice

Peptide p5 binds both heparinase-sensitive glycosaminoglycans and fibrils in patient-derived AL amyloid extracts

Quantitative high-resolution microradiographic imaging of amyloid deposits in a novel murine model of AA amyloidosis

Radioimaging of light chain amyloid with a fibril-reactive monoclonal antibody

Therapeutic potential of chimeric amyloid-reactive monoclonal antibody 11-1F4.

A binding-site barrier affects imaging efficiency of high affinity amyloid-reactive peptide radiotracers in vivo

Phage display and peptide mapping of an immunoglobulin light chain fibril-related conformational epitope

LnPO4 nanoparticles doped with Ac-225 and sequestered daughters for targeted alpha therapy

Immunodiagnostic capabilities of anti-free immunoglobulin light chain monoclonal antibodies

Dynamic PET and SPECT imaging with radioiodinated, amyloid-reactive peptide p5 in mice: a positive role for peptide dehalogenation.

Comparative evaluation of p5+14 with SAP and peptide p5 by dual-energy SPECT imaging of mice with AA amyloidosis.

Phagocyte depletion inhibits AA amyloid accumulation in AEF-induced huIL-6 transgenic mice

Preliminary evaluation of serial (18) FDG-PET/CT to assess response to toceranib phosphate therapy in canine cancer.

Characterization of X-ray Dose in Murine Animals Using microCT, a New Low-Dose Detector and nanoDot Dosimeters

ODAM Expression Inhibits Human Breast Cancer Tumorigenesis.

Immunoglobulin Light Chains Form an Extensive and Highly Ordered Fibril Involving the N- and C-Termini.

The N-terminal strand modulates immunoglobulin light chain fibrillogenesis.

Secondary structure propensity and chirality of the amyloidophilic peptide p5 and its analogues impacts ligand binding - In vitro characterization

Novel heparan sulfate-binding peptides for blocking herpesvirus entry.

A novel method for quantifying peripheral tissue amyloid load by using the radiolabeled amyloidophilic peptide, p5

SPECT imaging of peripheral amyloid in mice by targeting hyper-sulfated heparan sulfate proteoglycans with specific scFv antibodies.

Guidance for Methods Descriptions Used in Preclinical Imaging Papers