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List of works by Tudor A Fulga

A genome-wide transgenic resource for conditional expression of Drosophila microRNAs

scientific article

A multiplexable TALE-based binary expression system for in vivo cellular interaction studies.

scientific article published on 21 November 2017

A neuroprotective role for the DNA damage checkpoint in tauopathy

scientific article published in February 2012

A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs

scientific article published on 17 June 2015

ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts.

scientific article published on 26 November 2015

Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo

scientific article published on 24 December 2006

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

scientific article published in March 2007

BDNF promotes axon branching of retinal ganglion cells via miRNA-132 and p250GAP.

scientific article published on January 2014

CRISPR-Cas9 targeting of MMP13 in human chondrocytes leads to significantly reduced levels of the metalloproteinase and enhanced type II collagen accumulation

scientific article published on 15 September 2018

Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7

scientific article

Crystal structure of PTP-SL/PTPBR7 catalytic domain: implications for MAP kinase regulation

scientific article

Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression

scientific article published on 02 April 2019

Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease.

scientific article published on 21 July 2016

Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau

scientific article

Engineering Synthetic Signaling Pathways with Programmable dCas9-Based Chimeric Receptors.

scientific article published on September 2017

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

scientific article published on 03 December 2021

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering

scientific article published on 13 December 2017

Interrogation of Functional miRNA-Target Interactions by CRISPR/Cas9 Genome Engineering

scientific article

Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo

scientific article

MicroRNA-276a Functions in Ellipsoid Body and Mushroom Body Neurons for Naive and Conditioned Olfactory Avoidance inDrosophila ⬇️

scientific article published on March 27, 2013

MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells

scientific article published on 19 May 2015

MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila

scientific article published on 01 June 2018

Modeling spinal muscular atrophy in Drosophila

scientific article

Oxidative stress mediates tau-induced neurodegeneration in Drosophila

scientific article published on 14 December 2006

Precise tuning of gene expression levels in mammalian cells

article

Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

scientific article published on 03 March 2017

Regulation of Circadian Behavior by Astroglial MicroRNAs in Drosophila

scientific article published on 01 March 2018

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

scientific article published on 21 February 2020

Synapses and growth cones on two sides of a highwire.

scientific article published on February 2008

The Drosophila homologue of MEGF8 is essential for early development.

scientific article

The Drosophila tricellular junction protein Gliotactin regulates its own mRNA levels through BMP-mediated induction of miR-184.

scientific article published on 16 February 2016

The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells

scientific article published on 27 February 2020

Tiny giants of gene regulation: experimental strategies for microRNA functional studies

scientific article

Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms.

scientific article

Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development.

scientific article published on 22 August 2017

Understanding functional miRNA-target interactions in vivo by site-specific genome engineering.

scientific article

Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase

scientific article

miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons

scientific article

microRNAs That Promote or Inhibit Memory Formation in Drosophila melanogaster

scientific article published in June 2015

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