List of works - Brian A Joughin

A computational method for the analysis and prediction of protein:phosphopeptide-binding sites.

scientific article

A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth

scientific article

Acidification of Tumor at Stromal Boundaries Drives Transcriptome Alterations Associated with Aggressive Phenotypes

scientific article published on 12 February 2019

Action-at-a-distance interactions enhance protein binding affinity.

scientific article published on 31 March 2005

An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing glioblastoma cells

scientific article

Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs

scientific article published on 24 May 2019

Comprehensive substrate specificity profiling of the human nek kinome reveals unexpected signaling outputs

DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme.

scientific article published on 28 October 2016

Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition

scientific article published on 6 March 2018

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

scientific article published in Nature Communications

Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition

scientific article published on 02 June 2020

PTMScout, a Web resource for analysis of high throughput post-translational proteomics studies

scientific article

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena

scientific article

Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration

scientific article published on 01 December 2020

Protein kinases display minimal interpositional dependence on substrate sequence: potential implications for the evolution of signalling networks ⬇️

scientific article published on September 19, 2012

Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding

scientific article

Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome

scientific article

Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function

scientific article published on 09 July 2018

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling

scientific article

Systems Approaches to Cancer Biology

scientific article

Thermodynamics of interactions between amino acid side chains: experimental differentiation of aromatic-aromatic, aromatic-aliphatic, and aliphatic-aliphatic side-chain interactions in water.

scientific article published on May 1999

Tissue-Specific Oncogenic Activity of KRASA146T

scientific article published on 05 April 2019

List of works by Brian A Joughin

A computational method for the analysis and prediction of protein:phosphopeptide-binding sites.

A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth

Acidification of Tumor at Stromal Boundaries Drives Transcriptome Alterations Associated with Aggressive Phenotypes

Action-at-a-distance interactions enhance protein binding affinity.

An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing glioblastoma cells

Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs

Comprehensive substrate specificity profiling of the human nek kinome reveals unexpected signaling outputs

DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme.

Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition

PTMScout, a Web resource for analysis of high throughput post-translational proteomics studies

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena

Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration

Protein kinases display minimal interpositional dependence on substrate sequence: potential implications for the evolution of signalling networks ⬇️

Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding

Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome

Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling

Systems Approaches to Cancer Biology

Thermodynamics of interactions between amino acid side chains: experimental differentiation of aromatic-aromatic, aromatic-aliphatic, and aliphatic-aliphatic side-chain interactions in water.

Tissue-Specific Oncogenic Activity of KRASA146T