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List of works by Jonathan S Marchant

'Death and axes': unexpected Ca²⁺ entry phenologs predict new anti-schistosomal agents

scientific article (publication date: February 2014)

5-Azido-8-ethynyl-NAADP: A bifunctional, clickable photoaffinity probe for the identification of NAADP receptors

scientific article published on 04 December 2018

A C-terminal region dictates the apical plasma membrane targeting of the human sodium-dependent vitamin C transporter-1 in polarized epithelia

scientific article

A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors

scientific article

A continuum of InsP3‐mediated elementary Ca2+ signalling events in Xenopus oocytes ⬇️

scientific article published on May 15, 1998

A novel biological activity of praziquantel requiring voltage-operated Ca2+ channel beta subunits: subversion of flatworm regenerative polarity

scientific article published in 2009

A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca signaling in human cells

scientific article published on 16 August 2018

Activation and co-ordination of InsP3-mediated elementary Ca2+ events during global Ca2+ signals in Xenopus oocytes.

scientific article published in May 1998

Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers.

scientific article published on 18 April 2018

Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia.

scientific article

Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2

scientific article (publication date: November 2006)

Ca2+ Signaling and Regeneration

scientific article published on 01 November 2019

Ca2+ channels and praziquantel: A view from the free world ⬇️

scientific article published on December 16, 2012

Calcium influx: beyond 'current' biology

scientific article published in July 2006

Cell biology of the human thiamine transporter-1 (hTHTR1). Intracellular trafficking and membrane targeting mechanisms.

scientific article published on 25 November 2002

Characterization of a flatworm inositol (1,4,5) trisphosphate receptor (IP₃R) reveals a role in reproductive physiology

scientific article published on 5 March 2013

Characterization of a new type of neuronal 5-HT G- protein coupled receptor in the cestode nervous system

scientific article published on 11 November 2021

Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy

scientific article published on 30 July 2018

Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity.

scientific article published in July 1997

Correction: Mitochondrial Uptake of Thiamin Pyrophosphate: Physiological and Cell Biological Aspects

scientific article published on 11 October 2017

Dataset for a Dugesia japonica de novo transcriptome assembly, utilized for defining the voltage-gated like ion channel superfamily

scientific article published on 16 November 2016

Differential expression of human riboflavin transporters -1, -2, and -3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake.

scientific article

Disaccharide Polyphosphates Based upon Adenophostin A Activate Hepatic d-myo-Inositol 1,4,5-Trisphosphate Receptors ⬇️

scientific article published on October 21, 1997

Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria.

scientific article

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition

scientific article

Enhanced Ca2+ leak from ER Ca2+ stores induced by hepatitis C NS5A protein.

scientific article published on 5 February 2008

Enterotoxigenic Escherichia coli (ETEC) heat labile enterotoxin inhibits intestinal ascorbic acid uptake via a cAMP-dependent NF-κB mediated pathway

scientific article published on 04 October 2018

Ergot Alkaloids (Re)generate New Leads as Antiparasitics

scientific article

Expression and functional contribution of hTHTR-2 in thiamin absorption in human intestine.

scientific article published on 13 November 2003

Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis

scientific article

Heterologous Protein Expression in the Xenopus Oocyte.

scientific article published on 5 December 2017

Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel

scientific article published on 03 November 2021

Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanism(s).

scientific article

Inhibitory actions of GABA on rabbit urinary bladder muscle strips: mediation by potassium channels ⬇️

scientific article published on May 1, 1995

Initiation of IP(3)-mediated Ca(2+) waves in Xenopus oocytes.

scientific article published on October 1999

Inositol (1,4,5)-Trisphosphate Receptor Microarchitecture Shapes Ca2+ Puff Kinetics ⬇️

scientific article published on February 16, 2011

Intracellular trafficking and membrane targeting mechanisms of the human reduced folate carrier in Mammalian epithelial cells.

scientific article

Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist

scientific article published on 23 June 2016

Kinetics of elementary Ca2+ puffs evoked in Xenopus oocytes by different Ins(1,4,5)P3 receptor agonists ⬇️

scientific article published on September 15, 1998

Making heads or tails: planarian stem cells in the classroom

scientific article published on May 2014

Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

scientific article published on 16 December 2021

Membrane targeting and intracellular trafficking of the human sodium-dependent multivitamin transporter in polarized epithelial cells.

scientific article

MicroRNA-103a regulates sodium-dependent vitamin C transporter-1 expression in intestinal epithelial cells

scientific article published on 07 December 2018

Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects

scientific article

Modulation of elementary calcium release mediates a transition from puffs to waves in an IP3R cluster model

scientific article published on 8 January 2015

Modulation of function of sodium-dependent vitamin C transporter 1 (SVCT1) by Rab8a in intestinal epithelial cells: studies utilizing Caco-2 cells and Rab8a knockout mice

scientific article published on 27 September 2012

Molecular characterization of a novel intracellular ADP-ribosyl cyclase

scientific article

Molecular determinants dictating cell surface expression of the human sodium-dependent vitamin C transporter-2 in human liver cells

scientific article

Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract

scientific article published on 8 December 2016

N-Glycosylation is required for Na+-dependent vitamin C transporter functionality

scientific article

NAADP-dependent Ca signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system

scientific article published on 09 August 2018

Opposing roles of voltage-gated Ca2+ channels in neuronal control of regenerative patterning.

scientific article

Pharmacological and Functional Genetic Assays to Manipulate Regeneration of the Planarian <em>Dugesia japonica</em> ⬇️

scientific article published on August 31, 2011

Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist

scientific article published on 23 June 2016

Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg

scientific article

Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells

scientific article

Polarized expression of members of the solute carrier SLC19A gene family of water-soluble multivitamin transporters: implications for physiological function.

scientific article published on November 2003

Probing Ca2+ release mechanisms using sea urchin egg homogenates

scientific article published on 21 February 2019

Rapid Activation and Partial Inactivation of Inositol Trisphosphate Receptors by Inositol Trisphosphate ⬇️

scientific article published on August 18, 1998

Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling.

scientific article published on 12 November 2012

Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells.

scientific article

Structure-activity profiling of alkaloid natural product pharmacophores against a Schistosoma serotonin receptor

scientific article published on 28 September 2018

TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells

scientific article published on 02 May 2019

TPC1 Knockout Knocks Out TPC1.

scientific article published on May 2015

Targeting and intracellular trafficking of clinically relevant hTHTR1 mutations in human cell lines

scientific article

The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation

scientific article

The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel

scientific article published on 25 October 2019

The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand

scientific article

The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels.

scientific article published on 06 May 2011

The inositol 1,4,5-trisphosphate receptor (Itpr) gene family in Xenopus: identification of type 2 and type 3 inositol 1,4,5-trisphosphate receptor subtypes.

scientific article

The synthesis and characterization of a clickable-photoactive NAADP analog active in human cells

scientific article published on 01 August 2019

Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells

scientific article published on 13 September 2007

Timing in cellular Ca2+ signaling

scientific article published on September 2008

Tumor Necrosis Factor alpha (TNF-α) reduces intestinal vitamin C uptake: a role for NF-κB mediated signaling.

scientific article

Two-pore channels at the intersection of endolysosomal membrane traffic

scientific article

Unique pharmacological properties of serotonergic G-protein coupled receptors from cestodes.

scientific article published on 9 February 2018

Utilizing the planarian voltage-gated ion channel transcriptome to resolve a role for a Ca2+ channel in neuromuscular function and regeneration

scientific article

Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE-19) cells: mechanism and regulation

scientific article

Xenopus tropicalis oocytes as an advantageous model system for the study of intracellular Ca(2+) signalling ⬇️

scientific article

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