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List of works by Francesco Grossi

A cross-market cost comparison of erlotinib versus pemetrexed for first-line maintenance treatment of patients with locally advanced or metastatic non-small-cell lung cancer.

scientific article

A randomised phase II study of docetaxel/oxaliplatin and docetaxel in patients with previously treated non-small cell lung cancer: an Alpe-Adria Thoracic Oncology Multidisciplinary group trial (ATOM 019).

scientific article published on 20 April 2011

A randomised phase II trial of two sequential schedules of docetaxel and cisplatin followed by gemcitabine in patients with advanced non-small-cell lung cancer

scientific article published on 21 July 2011

A randomized, double-blind, phase II study of erlotinib with or without sunitinib for the second-line treatment of metastatic non-small-cell lung cancer (NSCLC).

scientific article

Adjuvant chemotherapy for non-small cell lung cancer: ready for clinical practice?

scientific article

Advanced non-small cell lung cancer management in patients progressing after first-line treatment: results of the cross-sectional phase of the Italian LIFE observational study

scientific article published on 6 June 2014

Advances in treatment of mesothelioma.

scientific article published on 7 April 2016

Afatinib beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib: phase III randomized LUX-Lung 5 trial

scientific article published on 8 December 2015

Afatinib for the treatment of advanced non-small-cell lung cancer.

scientific article published on April 2014

Afatinib resistance in non-small cell lung cancer involves the PI3K/AKT and MAPK/ERK signalling pathways and epithelial-to-mesenchymal transition.

scientific article

Alternating bolus and continuous infusion 5-fluorouracil: a strategy to overcome resistance to this fluoropyrimidine in advanced colorectal cancer patients.

scientific article

An expanded access program of erlotinib (Tarceva) in patients with advanced non-small cell lung cancer (NSCLC): data report from Italy

scientific article

Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.

scientific article

Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression

scientific article

Belagenpumatucel-L for the treatment of non-small cell lung cancer

scientific article published on 27 July 2015

Buccal mucosa cells as in vivo model to evaluate gefitinib activity in patients with advanced non small cell lung cancer

scientific article published in November 2007

CD133-Positive Cells from Non-Small Cell Lung Cancer Show Distinct Sensitivity to Cisplatin and Afatinib

scientific article

CIMAvax-EGF, a therapeutic non-small cell lung cancer vaccine

scientific article published on 04 July 2018

Circulating Cell-Free DNA and Circulating Tumor Cells as Prognostic and Predictive Biomarkers in Advanced Non-Small Cell Lung Cancer Patients Treated with First-Line Chemotherapy.

scientific article published on 11 May 2017

Circulating tumor DNA reflects tumor metabolism rather than tumor burden in chemotherapy-naive patients with advanced non-small cell lung cancer (NSCLC): an (18)F-FDG PET/CT study

scientific article published on 27 April 2017

Clinical Applications of Circulating Tumor Cells in Lung Cancer Patients by CellSearch System

scientific article

Clinical evidence for second- and third-line treatment options in advanced non-small cell lung cancer.

scientific article published on January 2008

Clinical significance and treatment of skin rash from erlotinib in non-small cell lung cancer patients: results of an Experts Panel Meeting.

scientific article

Comparison of treatment costs of grade 3/4 adverse events associated with erlotinib or pemetrexed maintenance therapy for patients with advanced non-small-cell lung cancer (NSCLC) in Germany, France, Italy, and Spain.

scientific article published on 17 May 2011

Cost-effectiveness analysis of bevacizumab versus pemetrexed for advanced non-squamous NSCLC in Italy ⬇️

scientific article published on August 1, 2010

Cross-market cost-effectiveness analysis of erlotinib as first-line maintenance treatment for patients with stable non-small cell lung cancer

scientific article published on 26 January 2012

DISRUPT: a randomised phase 2 trial of ombrabulin (AVE8062) plus a taxane-platinum regimen as first-line therapy for metastatic non-small cell lung cancer.

scientific article published on 21 May 2014

ERCC1/BRCA1 expression and gene polymorphisms as prognostic and predictive factors in advanced NSCLC treated with or without cisplatin

scientific article published on 2 April 2013

Easternmost Mediterranean evidence of the Zanclean flooding event and subsequent surface uplift: Adana Basin, southern Turkey

Efficacy of motesanib diphosphate in non-small-cell lung cancer

scientific article published on August 2014

Evaluation of CTLA-4 expression and relevance as a novel prognostic factor in patients with non-small cell lung cancer.

scientific article published on 9 February 2012

Evaluation of antitumor activity using change in tumor size of the survivin antisense oligonucleotide LY2181308 in combination with docetaxel for second-line treatment of patients with non-small-cell lung cancer: a randomized open-label phase II stu

scientific article published on November 2014

Exosomes: a new horizon in lung cancer.

scientific article

Expression of Ribonucleotide Reductase Subunit-2 and Thymidylate Synthase Correlates with Poor Prognosis in Patients with Resected Stages I-III Non-Small Cell Lung Cancer

scientific article

Fibroblast Growth Factor Receptor (FGFR): A New Target for Non-small Cell Lung Cancer Therapy

scientific article published on 3 February 2016

Free drugs in clinical trials and their potential cost saving impact on the National Health Service: A retrospective cost analysis in Italy ⬇️

scientific article published on May 4, 2013

Future scenarios for the treatment of advanced non-small cell lung cancer: focus on taxane-containing regimens.

scientific article published on 7 October 2010

Geography of clinical cancer research publications from 1995 to 1999.

scientific article

Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients

scientific article published on 29 August 2013

Hematopoietic growth factors in lung cancer.

scientific article

IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions

scientific article

IL-8 induces exocytosis of arginase 1 by neutrophil polymorphonuclears in nonsmall cell lung cancer

scientific article

Identifying an optimum treatment strategy for patients with advanced non-small cell lung cancer.

scientific article published on 19 February 2008

Impact of third-generation drugs on the activity of first-line chemotherapy in advanced non-small cell lung cancer: a meta-analytical approach.

scientific article published on 7 May 2009

In vitro study of CI-994, a histone deacetylase inhibitor, in non-small cell lung cancer cell lines.

scientific article

Induction chemotherapy followed by concurrent standard radiotherapy and daily low-dose cisplatin in locally advanced non-small-cell lung cancer

scientific article published on September 1999

Informal caregiving burden in advanced non-small cell lung cancer: the HABIT study.

scientific article published in June 2007

Information given to cancer patients on diagnosis, prognosis and treatment: the clinical oncologist's perspective

scientific article published on 01 August 2004

Investigational drugs targeting fibroblast growth factor receptor in the treatment of non-small cell lung cancer

scientific article published on 7 April 2017

Ipilimumab in non-small cell lung cancer and small-cell lung cancer: new knowledge on a new therapeutic strategy.

scientific article published on 05 April 2014

Italian Nivolumab Expanded Access Program in Nonsquamous Non–Small Cell Lung Cancer Patients: Results in Never-Smokers and EGFR-Mutant Patients

article

Italian, Multicenter, Phase III, Randomized Study of Cisplatin Plus Etoposide With or Without Bevacizumab as First-Line Treatment in Extensive-Disease Small-Cell Lung Cancer: The GOIRC-AIFA FARM6PMFJM Trial.

scientific article published on 30 January 2017

Looking for results in non-small-cell lung cancer: is bio-chemotherapy the right answer?

scientific article published on 11 July 2014

Low-dose computed tomography screening for lung cancer and pleural mesothelioma in an asbestos-exposed population: baseline results of a prospective, nonrandomized feasibility trial--an Alpe-adria Thoracic Oncology Multidisciplinary Group Study (ATO

scientific article published in October 2007

Lung Cancer Highlights from ASCO 2005.

scientific article published in January 2006

Maintenance chemotherapy in non-small cell lung cancer

scientific article published on 01 March 2006

Management of Italian patients with advanced non-small-cell lung cancer after second-line treatment: results of the longitudinal phase of the LIFE observational study.

scientific article published on 14 May 2014

Management of malignant pleural effusions

scientific article published on 01 January 1998

Management of non-small cell lung in cancer patients with stable disease.

scientific article published on June 2012

Molecular Profiling and Novel Therapeutic Strategies for Mucosal Melanoma: A Comprehensive Review

scientific article published in 2021

NGR-hTNF and Doxorubicin as Second-Line Treatment of Patients with Small Cell Lung Cancer

scientific article published on 03 August 2018

NGR-hTNF in combination with best investigator choice in previously treated malignant pleural mesothelioma (NGR015): a randomised, double-blind, placebo-controlled phase 3 trial

scientific article published on 09 May 2018

New perspectives for the pharmacological and biological therapy of small cell lung cancer.

scientific article

New perspectives in second-line treatment in non-squamous non-small cell lung cancer

scientific article published in December 2016

New systemic strategies for overcoming resistance to targeted therapies in non-small cell lung cancer.

scientific article published on 14 November 2016

Next generation sequencing in non-small cell lung cancer: new avenues toward the personalized medicine

scientific article published on January 2015

Next-Generation Sequencing Workflow for NSCLC Critical Samples Using a Targeted Sequencing Approach by Ion Torrent PGM™ Platform

scientific article

Oral vinorelbine in the treatment of non-small-cell lung cancer.

scientific article published on 27 June 2014

Oral vinorelbine plus cisplatin versus pemetrexed plus cisplatin as first-line treatment of advanced non-squamous non-small-cell lung cancer: cost minimization analysis in 12 European countries.

scientific article

PCSK9 is a promising prognostic marker in patients with advanced NSCLC

scientific article published on 14 January 2020

Paclitaxel, cisplatin and 5-fluorouracil in recurrent squamous cell carcinoma of the head and neck: a phase II trial from an Italian cooperative group.

scientific article

Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.

scientific article published on 16 April 2018

Pemetrexed for the treatment of non-small cell lung cancer.

scientific article published on 17 May 2013

Pemetrexed plus carboplatin in elderly patients with malignant pleural mesothelioma: combined analysis of two phase II trials.

scientific article

Performance comparison of two commercial human whole-exome capture systems on formalin-fixed paraffin-embedded lung adenocarcinoma samples.

scientific article

Phase II randomized study of vandetanib plus gemcitabine or gemcitabine plus placebo as first-line treatment of advanced non-small-cell lung cancer in elderly patients.

scientific article

Phase II study of afatinib, an irreversible ErbB family blocker, in EGFR FISH-positive non-small-cell lung cancer.

scientific article

Phase II study of first-line bortezomib and cisplatin in malignant pleural mesothelioma and prospective validation of progression free survival rate as a primary end-point for mesothelioma clinical trials (European Organisation for Research and Trea

scientific article

Phase II study of pemetrexed plus carboplatin in malignant pleural mesothelioma

scientific article published on 01 March 2006

Phase II study of sunitinib in patients with non-small cell lung cancer and irradiated brain metastases.

scientific article

Phase III study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer.

scientific article published on 8 March 2010

Pleural and peripheral lung lesions: comparison of US- and CT-guided biopsy

scientific article

Potential cardiac risk of immune-checkpoint blockade as anticancer treatment: What we know, what we do not know, and what we can do to prevent adverse effects

scientific article published on 28 December 2017

Predictive value of a proteomic signature in patients with non-small-cell lung cancer treated with second-line erlotinib or chemotherapy (PROSE): a biomarker-stratified, randomised phase 3 trial.

scientific article published on 13 May 2014

Prognostic and Therapeutic Implications of MicroRNA in Malignant Pleural Mesothelioma.

scientific article published on 28 January 2016

Prognostic and predictive relevance of circulating tumor cells in patients with non-small-cell lung cancer.

scientific article

Prognostic role of the VeriStrat test in first line patients with non-small cell lung cancer treated with platinum-based chemotherapy

scientific article published on 13 December 2017

Prognostic significance of K-ras, p53, bcl-2, PCNA, CD34 in radically resected non-small cell lung cancers.

scientific article

Ramucirumab: preclinical research and clinical development.

scientific article

Randomized phase III PITCAP trial and meta-analysis of induction chemotherapy followed by thoracic irradiation with or without concurrent taxane-based chemotherapy in locally advanced NSCLC.

scientific article published on 27 July 2016

Randomized phase IIIb trial evaluating the continuation of bevacizumab beyond disease progression in patients with advanced non-squamous non-small-cell lung cancer after first-line treatment with bevacizumab plus platinum-based chemotherapy: treatme

scientific article published on 25 June 2011

Recent advances in squamous non-small cell lung cancer: evidence beyond predictive biomarkers.

scientific article published on 15 November 2015

Releasing the brake: safety profile of immune check-point inhibitors in non-small cell lung cancer.

scientific article published on 29 March 2017

Reply to the Letter to the Editor by C. Nicolazzo et al.: "Circulating Cell-Free DNA and Circulating Tumor Cells as Prognostic and Predictive Biomarkers in Advanced Non-Small Cell Lung Cancer Patients Treated with First-Line Chemotherapy".

scientific article published on 19 June 2017

Resistin is associated with overall survival in non-small cell lung cancer patients during nivolumab treatment

scientific article published on 11 February 2020

Role of immunotherapy in the treatment of advanced non-small-cell lung cancer.

scientific article published on January 2014

Role of microRNAs in malignant mesothelioma.

scientific article published on 23 February 2014

Safety and Efficacy of Bevacizumab Plus Standard-of-Care Treatment Beyond Disease Progression in Patients With Advanced Non-Small Cell Lung Cancer: The AvaALL Randomized Clinical Trial

scientific article published on 13 December 2018

Safety and Efficacy of Buparlisib (BKM120) in Patients with PI3K Pathway-Activated Non-Small Cell Lung Cancer: Results from the Phase II BASALT-1 Study

scientific article

Schedule specific biochemical modulation of 5-fluorouracil in advanced colorectal cancer: a randomized study. GISCAD, IOR and collaborating centers

scientific article published on 01 November 2000

Second-line Treatment of Advanced Non-small Cell Lung Cancer Non-oncogene Addicted: New Treatment Algorithm in the Era of Novel Immunotherapy

scientific article published on 01 January 2018

Sequential chemotherapy with paclitaxel plus cisplatin, followed by vinorelbine, followed by gemcitabine in advanced non-small cell lung cancer: an Alpe-Adria Thoracic Oncology Multidisciplinary group study (ATOM 001).

scientific article published in October 2004

Sequential use of vinorelbine followed by gefitinib enhances the antitumor effect in NSCLC cell lines poorly responsive to reversible EGFR tyrosine kinase inhibitors.

scientific article

Serial Troponin for Early Detection of Nivolumab Cardiotoxicity in Advanced Non-Small Cell Lung Cancer Patients

scientific article published on 22 March 2018

Serum PCSK9 levels at the second nivolumab cycle predict overall survival in elderly patients with NSCLC: a pilot study

scientific article published on 20 July 2019

Serum proteomic test in advanced non-squamous non-small cell lung cancer treated in first line with standard chemotherapy.

scientific article published on 29 November 2016

Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity.

scientific article published on 10 September 2009

The activity of raltitrexed (Tomudex) in malignant pleural mesothelioma: an EORTC phase II study (08992)

scientific article (publication date: February 2003)

The administration of gefitinib in patients with advanced non-small-cell lung cancer after the failure of erlotinib.

scientific article published on 21 February 2012

The evolving role of pemetrexed disodium for the treatment of non-small cell lung cancer

article

Third- and further-line therapy in advanced non-small-cell lung cancer patients: an overview

scientific article

To treat or not to treat advanced non-small-cell lung cancer patients with impaired performance status?

scientific article published on 01 October 2005

Triage process for the assessment of coronavirus disease 2019-positive patients with cancer: The ONCOVID prospective study

scientific article published on 03 December 2020

Triplets versus doublets, with or without cisplatin, in the first-line treatment of stage IIIB-IV non-small cell lung cancer (NSCLC) patients: a multicenter randomised factorial trial (FAST).

scientific article published on 12 January 2012

Tumor measurements on computed tomographic images of non-small cell lung cancer were similar among cancer professionals from different specialties.

scientific article

Tumor microenvironment as a potential source of clinical biomarkers in non-small cell lung cancer: can we use enemy territory at our advantage?

scientific article published in November 2017

Uncommon EGFR Exon 19 Mutations Confer Gefitinib Resistance in Advanced Lung Adenocarcinoma.

scientific article

Understanding the checkpoint blockade in lung cancer immunotherapy

scientific article

Use of nivolumab in elderly patients with advanced squamous non-small-cell lung cancer: results from the Italian cohort of an expanded access programme

article

Vinflunine for the treatment of non-small cell lung cancer.

scientific article

Whole exome sequencing of independent lung adenocarcinoma, lung squamous cell carcinoma, and malignant peritoneal mesothelioma: A case report

scientific article

[Checkpoint inhibitors in the decision-making algorithm of advanced non-small-cell lung cancer.]

scientific article published on 01 June 2018

“Earliest Zanclean age for the Colombacci and uppermost Di Tetto formations of the « latest Messinian » northern Apennines: New palaeoenvironmental data from the Maccarone section (Marche Province, Italy)” by Popescu et al. (2007) Geobios 40 (3

article

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