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List of works by Roman Kondratov

A role of the circadian system and circadian proteins in aging.

scientific article

Aging and calorie restriction regulate the expression of miR-125a-5p and its target genes Stat3, Casp2 and Stard13.

scientific article published on July 2017

Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1.

scientific article published on 30 December 2009

BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system

scientific journal article

BMAL1-dependent regulation of the mTOR signaling pathway delays aging

scientific journal article

CR reprograms acetyl-CoA metabolism and induces long-chain acyl-CoA dehydrogenase and CrAT expression

scientific article published on 26 October 2020

Calorie restriction effects on circadian rhythms in gene expression are sex dependent.

scientific article published on 29 August 2017

Calorie restriction regulates circadian clock gene expression through BMAL1 dependent and independent mechanisms.

scientific article published on 12 May 2016

Circadian Clock Genes Are Essential for Normal Adult Neurogenesis, Differentiation, and Fate Determination

scientific article published on 6 October 2015

Circadian clock and cancer therapy: an unexpected journey

scientific article published in June 2014

Circadian clock genes as modulators of sensitivity to genotoxic stress.

scientific article

Circadian clock protein BMAL1 regulates cellular senescence in vivo

scientific journal article

Circadian clock proteins control adaptation to novel environment and memory formation.

scientific article

Circadian clocks govern calorie restriction-mediated life span extension through BMAL1- and IGF-1-dependent mechanisms

scientific article published on 23 December 2015

Circadian clocks, diets and aging.

scientific article

Circadian proteins in the regulation of cell cycle and genotoxic stress responses.

scientific article published on 20 July 2007

Circadian regulation of cell cycle: Molecular connections between aging and the circadian clock.

scientific article published on September 2010

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

scientific journal article

Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex

scientific article

Circadian transcription factor BMAL1 regulates innate immunity against select RNA viruses

scientific article published on December 2016

Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation.

scientific article published on 18 January 2017

Deficiency of circadian clock protein BMAL1 in mice results in a low bone mass phenotype

scientific article published on 11 January 2016

Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice

scientific article

Development of circadian oscillators in neurosphere cultures during adult neurogenesis

scientific article

Disruption of actin microfilaments by cytochalasin D leads to activation of p53.

scientific article

Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis.

scientific article published on 10 March 2008

Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice.

scientific article published in April 2004

Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation.

scientific article

Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock

scientific article (publication date: 15 July 2006)

Metabolic clock generates nutrient anticipation rhythms in mTOR signaling

scientific article

Mutation of p53 is necessary for stable transformation of REF52 cells by myc+ras oncogenes

scientific article published on 01 March 2000

Pharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapy

scientific article

Poliovirus protein 3A binds and inactivates LIS1, causing block of membrane protein trafficking and deregulation of cell division.

scientific article published on 20 October 2005

Post-translational regulation of circadian transcriptional CLOCK(NPAS2)/BMAL1 complex by CRYPTOCHROMES.

scientific article published on 17 April 2006

Quercetinase pirin makes poliovirus replication resistant to flavonoid quercetin.

scientific article published on April 2008

Rapamycin in preventive (very low) doses

scientific article published on March 2014

Reduced caloric intake and periodic fasting independently contribute to metabolic effects of caloric restriction

scientific article published on 11 March 2020

Selection-subtraction approach (SSA): a universal genetic screening technique that enables negative selection

scientific article

Small molecules that dramatically alter multidrug resistance phenotype by modulating the substrate specificity of P-glycoprotein

scientific article

The ability of protein tyrosine phosphatase SHP-1 to suppress NFkappaB can be inhibited by dominant negative mutant of SIRPalpha.

scientific article published in March 2004

The circadian clock and pathology of the ageing brain ⬇️

scientific article published on March 7, 2012

The role of mammalian circadian proteins in normal physiology and genotoxic stress responses.

scientific article published on January 2007

Transcriptional control of antioxidant defense by the circadian clock

scientific article

[Expression of human urokinase in inoculated rodent cells. Loss of introns during gene transfer using a retroviral vector]

scientific article published on 01 January 1992

[Functional heterogeneity of p53-responsive elements]

scientific article published on 01 May 1996

[Gene for the human tissue activator plasminogen: regulation of expression by signals, located in the 3'-untranslated region]

scientific article published on 01 May 1999

[Phosphorylation of 5'-O-phosphonylmethylthymidine and its incorporation into HeLa cells DNA]

scientific article published on 01 January 1998

[Retroviral transfer and expression of human chorionic gonadotropic hormone in cultured rodent cells]

scientific article published on 01 January 1992

[The human adenosine deaminase gene contains a p53-responsive element]

scientific article published on 01 January 1996

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