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List of works by Andrew Macdonald

Agnoprotein Is an Essential Egress Factor during BK Polyomavirus Infection. ⬇️

scientific article published on 19 March 2018

Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Akt - NF?B - IL-6 signalling axis

scientific article published on 29 December 2018

Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1-NFκB-IL-6 signalling axis

scientific article published on 21 June 2019

Characterization of the cellular action of the MSK inhibitor SB-747651A.

scientific article published on January 2012

Children's injuries in a Scottish district general hospital

scientific article published on September 2005

Different NF-κB activation characteristics of human respiratory syncytial virus subgroups A and B.

scientific article published on 28 December 2011

ERK5 regulation in naïve T-cell activation and survival.

scientific article

Effect of the Large and Small T-Antigens of Human Polyomaviruses on Signaling Pathways

scientific article published on 12 August 2019

Emerging Roles of Viroporins Encoded by DNA Viruses: Novel Targets for Antivirals? ⬇️

scientific article

Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI.

scientific article published in November 2006

Expression of the NS3 protease of cytopathogenic bovine viral diarrhea virus results in the induction of apoptosis but does not block activation of the beta interferon promoter

scientific article published on 30 September 2009

Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling

scientific article

Hepatitis C virus NS5A protein blocks epidermal growth factor receptor degradation via a proline motif- dependent interaction ⬇️

scientific article published on 13 April 2015

Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular beta-catenin and stimulation of beta-catenin-responsive transcription

scientific article

Hepatitis C virus NS5A: tales of a promiscuous protein

scientific article

High-risk human papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small-molecule inhibitors ⬇️

scientific article

Human papillomavirus E7 oncoprotein increases production of the anti-inflammatory interleukin-18 binding protein in keratinocytes. ⬇️

scientific article

Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle ⬇️

scientific article published on 6 October 2017

IL-18 and skin inflammation

scientific article published on 11 March 2009

Identification of TRIM23 as a cofactor involved in the regulation of NF-kappaB by human cytomegalovirus

scientific article published on 28 January 2009

Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS.

scientific article published on March 2007

Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer

scientific article published on 22 February 2022

Introduction of replication-competent hepatitis C virus transcripts using a tetracycline-regulable baculovirus delivery system

scientific article published on February 2004

JAK2 Inhibition Impairs Proliferation and Sensitises Cervical Cancer Cells to Cisplatin-Induced Cell Death

scientific article published on 04 December 2019

MSK regulate TCR-induced CREB phosphorylation but not immediate early gene transcription.

scientific article published on September 2007

Manipulation of JAK/STAT Signalling by High-Risk HPVs: Potential Therapeutic Targets for HPV-Associated Malignancies

scientific article published on 03 September 2020

Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation ⬇️

scientific article published in November 2017

Merkel cell polyomavirus small T antigen mediates microtubule destabilization to promote cell motility and migration ⬇️

scientific article published on 15 October 2014

Merkel cell polyomavirus small T antigen targets the NEMO adaptor protein to disrupt inflammatory signaling

scientific article published on 9 October 2013

Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus ⬇️

scientific article

MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer

scientific article published on 18 June 2020

New Structural Insights into the Genome and Minor Capsid Proteins of BK Polyomavirus using Cryo-Electron Microscopy ⬇️

scientific article published on 16 March 2016

Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4

scientific article (publication date: December 2011)

Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection ⬇️

scientific article

Perturbation of epidermal growth factor receptor complex formation and Ras signalling in cells harbouring the hepatitis C virus subgenomic replicon

scientific article

Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

scientific article

Putting the brakes on the anti-viral response: negative regulators of type I interferon (IFN) production ⬇️

scientific article published on January 20, 2011

Quantitative proteomics using stable isotope labeling with amino acids in cell culture reveals changes in the cytoplasmic, nuclear, and nucleolar proteomes in Vero cells infected with the coronavirus infectious bronchitis virus

scientific article

STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle. ⬇️

scientific article published on 9 April 2018

Selective and Potent Proteomimetic Inhibitors of Intracellular Protein-Protein Interactions ⬇️

scientific article published on 30 January 2015

Selective and potent proteomimetic inhibitors of intracellular protein-protein interactions ⬇️

scientific article published on 4 February 2015

Stathmin drives virus-induced metastasis

scientific article published on 4 October 2015

Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence

scientific article (publication date: 15 September 2009)

The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade

scientific article published on 5 January 2004

The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors ⬇️

scientific article published on 21 April 2018

The cellular chloride channels CLIC1 and CLIC4 contribute to virus-mediated cell motility ⬇️

scientific article published on 8 February 2018

The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity

scientific article

The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling

scientific article published on 5 March 2003

The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes ⬇️

scientific article

Werner Syndrome Protein (WRN) Regulates Cell Proliferation and the Human Papillomavirus 16 Life Cycle during Epithelial Differentiation

scientific article published on 16 September 2020

YIP1 family member 4 (YIPF4) is a novel cellular binding partner of the papillomavirus E5 proteins ⬇️

scientific article published on 3 August 2015

miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity

scientific article

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