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List of works by Mariona Graupera

5-lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: a possible role of cysteinyl-leukotrienes

scientific article published in February 2002

A junctional PACSIN2/EHD4/MICAL-L1 complex coordinates VE-cadherin trafficking for endothelial migration and angiogenesis

scientific article published on 10 May 2021

ALK1 (Activin-Receptor Like Kinase 1) Loss Results in Vascular Hyperplasia in Mice and Humans Through PI3K (Phosphatidylinositol 3-Kinase) Activation.

scientific article published on 15 February 2018

Acute propranolol administration effectively decreases portal pressure in patients with TIPS dysfunction. Transjugular intrahepatic portosystemic shunt

scientific article published on January 2003

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.

scientific article published on 30 April 2008

Class I PI-3-Kinase Signaling Is Critical for Bone Formation Through Regulation of SMAD1 Activity in Osteoblasts.

scientific article

Crosstalk between reticular adherens junctions and platelet endothelial cell adhesion molecule-1 regulates endothelial barrier function

scientific article published on 21 June 2012

Cyclooxygenase-1 inhibition corrects endothelial dysfunction in cirrhotic rat livers

scientific article published in October 2003

Cyclooxygenase-derived products modulate the increased intrahepatic resistance of cirrhotic rat livers

scientific article published in January 2003

DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells.

scientific article

Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors

scientific article

Endothelial Cells: New Players in Obesity and Related Metabolic Disorders

scientific article published on 25 September 2018

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

scientific article published in Nature Communications

ErbBs inhibition by lapatinib blocks tumor growth in an orthotopic model of human testicular germ cell tumor.

scientific article

Erratum: The metabolic co-regulator PGC1α suppresses prostate cancer metastasis

scientific article published on 01 June 2017

Identification and functional characterization of the hepatic stellate cell CD38 cell surface molecule

scientific journal article

Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis

scientific article published on 16 September 2013

Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer

scientific article published on 11 October 2018

Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis.

scientific article

Large-conductance calcium-activated potassium channels modulate vascular tone in experimental cirrhosis

scientific article

Left ventricular hypertrophy in rats with biliary cirrhosis

scientific article published in September 2003

Metronomic chemotherapy following the maximum tolerated dose is an effective anti-tumour therapy affecting angiogenesis, tumour dissemination and cancer stem cells

scientific article published on 4 June 2013

Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

scientific article

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.

scientific article

PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia

scientific article published on 29 November 2016

PTEN mediates Notch-dependent stalk cell arrest in angiogenesis

scientific article

Regulation of angiogenesis by PI3K signaling networks

scientific article published on 13 March 2013

Resistance to Antiangiogenic Therapies by Metabolic Symbiosis in Renal Cell Carcinoma PDX Models and Patients.

scientific article

Resistance to Targeted Therapies in Renal Cancer: The Importance of Changing the Mechanism of Action.

scientific article published on 15 November 2016

Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.

scientific article published on 25 November 2015

Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats

scientific article published on 15 February 2007

Sinusoidal endothelial COX-1-derived prostanoids modulate the hepatic vascular tone of cirrhotic rat livers

scientific article published on 18 November 2004

Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans

scientific article published on March 2016

Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.

scientific article

Targeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapy

scientific article (publication date: 21 September 2016)

The PDGFRβ-AKT pathway contributes to CDDP-acquired resistance in testicular germ cell tumors

scientific article published on 25 November 2013

The TGFβ pathway stimulates ovarian cancer cell proliferation by increasing IGF1R levels.

scientific article published on 14 June 2016

The emerging mechanisms of isoform-specific PI3K signalling

scientific article (publication date: May 2010)

The loss of DHX15 impairs endothelial energy metabolism, lymphatic drainage and tumor metastasis in mice

scientific article published on 15 October 2021

Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry

scholarly article

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels.

scientific article published on 10 March 2015