List of works - John O Mason

Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3.

scientific article published on September 2006

Activation of Wnt/β-catenin signalling affects differentiation of cells arising from the cerebellar ventricular zone

scientific article

Analysis of axon guidance defects at the optic chiasm in heparan sulphate sulphotransferase compound mutant mice

scientific article published on 26 September 2011

Analysis of compound heterozygotes reveals that the mouse floxed Pax6 (tm1Ued) allele produces abnormal eye phenotypes.

scientific article published on 30 May 2016

Analysis of early ventral telencephalic defects in mice lacking functional Gli3 protein

scientific journal article

Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes

scientific article published in July 2002

Cerebral Cortex Expression of Gli3 Is Required for Normal Development of the Lateral Olfactory Tract

scientific article published on 28 October 2015

Cerebral organoids as tools to identify the developmental roots of autism

scientific article published on 13 July 2020

Challenges and future perspectives for 3D cerebral organoids as a model for complex brain disorders

article published in 2019

Comparison of two related lines of tauGFP transgenic mice designed for lineage tracing

scientific article

Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization

scientific article published on 3 January 2007

Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.

scientific article published in October 2002

Embryonic stem cells and transgenic mice ubiquitously expressing a tau-tagged green fluorescent protein.

scientific article published in December 2000

Evaluation of the mouse TgTP6.3 tauGFP transgene as a lineage marker in chimeras

scientific article published in January 2005

Expansion of the piriform cortex contributes to corticothalamic pathfinding defects in Gli3 conditional mutants

scientific article

Expression Profiles of Wnt Genes during Neural Differentiation of Mouse Embryonic Stem Cells

article

Expression of Barhl2 and its relationship with Pax6 expression in the forebrain of the mouse embryo

scientific article

Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis

scientific journal article

Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse

scientific article

Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through expression

scholarly article by Kerstin Hasenpusch-Theil published in August 2018

Gli3 is required autonomously for dorsal telencephalic cells to adopt appropriate fates during embryonic forebrain development

scientific article published on 24 December 2008

Heparan Sulfate Sulfation by Hs2st Restricts Astroglial Precursor Somal Translocation in Developing Mouse Forebrain by a Non-Cell-Autonomous Mechanism

scientific article published on 07 January 2019

Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development.

scientific article published in February 2011

Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development

scientific article published on February 2014

Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm.

scientific article published in June 2006

Hybridization parameters revisited: solutions containing SDS.

scientific article

Identification of genomic regions regulating Pax6 expression in embryonic forebrain using YAC reporter transgenic mouse lines

scientific article

Identifying GFP-transgenic animals by flashlight

scientific article published on 01 March 2003

Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency.

scientific article

Lateral cortical Cdca7 expression levels are regulated by Pax6 and influence the production of intermediate progenitors

scientific article

Long-range downstream enhancers are essential for Pax6 expression

scientific article published on 30 August 2006

Loss of Causes Regional Changes in Expression in Developing Cerebral Cortex

scientific article published on 06 March 2019

Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon

scientific journal article

Mouse vs man: Organoid models of brain development & disease

scientific article published on 29 August 2019

Newly identified patterns of Pax2 expression in the developing mouse forebrain

scientific article

Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice.

scientific article published on 05 June 2009

Novel lines of Pax6-/- embryonic stem cells exhibit reduced neurogenic capacity without loss of viability

scientific article

Pax3 regulates Wnt1 expression via a conserved binding site in the 5' proximal promoter.

scientific article published on 3 December 2007

Pax6 Lengthens G1 Phase and Decreases Oscillating Cdk6 Levels in Murine Embryonic Cortical Progenitors

scientific article published on 15 November 2018

Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb

scientific journal article

Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells

scientific article

Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor

scientific article published on 10 March 2015

Regulation of the Pax6 : Pax6(5a) mRNA ratio in the developing mammalian brain.

scientific article

Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice.

scientific article

Specific modification of heparan sulphate is required for normal cerebral cortical development

scientific article

The expression and activity of β-catenin in the thalamus and its projections to the cerebral cortex in the mouse embryo.

scientific article

The half-life of immunoglobulin mRNA increases during B-cell differentiation: a possible role for targeting to membrane-bound polysomes

scientific article published on 01 August 1988

The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels

scientific article

The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice

scientific article published on February 2010

The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse

scientific journal article

Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects.

scientific article published in June 2011

Wnt/β-catenin signalling is active in a highly dynamic pattern during development of the mouse cerebellum

scientific article

List of works by John O Mason

Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3.

Activation of Wnt/β-catenin signalling affects differentiation of cells arising from the cerebellar ventricular zone

Analysis of axon guidance defects at the optic chiasm in heparan sulphate sulphotransferase compound mutant mice

Analysis of compound heterozygotes reveals that the mouse floxed Pax6 (tm1Ued) allele produces abnormal eye phenotypes.

Analysis of early ventral telencephalic defects in mice lacking functional Gli3 protein

Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes

Cerebral Cortex Expression of Gli3 Is Required for Normal Development of the Lateral Olfactory Tract

Cerebral organoids as tools to identify the developmental roots of autism

Challenges and future perspectives for 3D cerebral organoids as a model for complex brain disorders

Comparison of two related lines of tauGFP transgenic mice designed for lineage tracing

Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization

Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.

Embryonic stem cells and transgenic mice ubiquitously expressing a tau-tagged green fluorescent protein.

Evaluation of the mouse TgTP6.3 tauGFP transgene as a lineage marker in chimeras

Expansion of the piriform cortex contributes to corticothalamic pathfinding defects in Gli3 conditional mutants

Expression Profiles of Wnt Genes during Neural Differentiation of Mouse Embryonic Stem Cells

Expression of Barhl2 and its relationship with Pax6 expression in the forebrain of the mouse embryo

Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis

Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse

Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through expression

Gli3 is required autonomously for dorsal telencephalic cells to adopt appropriate fates during embryonic forebrain development

Heparan Sulfate Sulfation by Hs2st Restricts Astroglial Precursor Somal Translocation in Developing Mouse Forebrain by a Non-Cell-Autonomous Mechanism

Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development.

Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development

Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm.

Hybridization parameters revisited: solutions containing SDS.

Identification of genomic regions regulating Pax6 expression in embryonic forebrain using YAC reporter transgenic mouse lines

Identifying GFP-transgenic animals by flashlight

Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency.

Lateral cortical Cdca7 expression levels are regulated by Pax6 and influence the production of intermediate progenitors

Long-range downstream enhancers are essential for Pax6 expression

Loss of Causes Regional Changes in Expression in Developing Cerebral Cortex

Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon

Mouse vs man: Organoid models of brain development & disease

Newly identified patterns of Pax2 expression in the developing mouse forebrain

Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice.

Novel lines of Pax6-/- embryonic stem cells exhibit reduced neurogenic capacity without loss of viability

Pax3 regulates Wnt1 expression via a conserved binding site in the 5' proximal promoter.

Pax6 Lengthens G1 Phase and Decreases Oscillating Cdk6 Levels in Murine Embryonic Cortical Progenitors

Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb

Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells

Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor

Regulation of the Pax6 : Pax6(5a) mRNA ratio in the developing mammalian brain.

Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice.

Specific modification of heparan sulphate is required for normal cerebral cortical development

The expression and activity of β-catenin in the thalamus and its projections to the cerebral cortex in the mouse embryo.

The half-life of immunoglobulin mRNA increases during B-cell differentiation: a possible role for targeting to membrane-bound polysomes

The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels

The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice

The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse

Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects.

Wnt/β-catenin signalling is active in a highly dynamic pattern during development of the mouse cerebellum