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List of works by Dennis C. Liotta

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Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols

scientific article
Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

scientific article published on July 2004
Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin

scientific article published on 24 June 2008
XMRV infection in patients with prostate cancer: novel serologic assay and correlation with PCR and FISH

scientific article
EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

scientific article published in March 2005
A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.

scientific article published on 5 October 2010
The Ecstasy and Agony of Assay Interference Compounds.

scientific article published on 28 February 2017
Highly active anticancer curcumin analogues

scientific article published on January 2007
Development of a unique small molecule modulator of CXCR4

scientific article published on April 2, 2012
Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators

scientific article
The Ecstasy and Agony of Assay Interference Compounds

Discovery of small molecule CXCR4 antagonists

scientific article published on 24 October 2007
EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1.

scientific article published on 09 June 2008
A target site for template-based design of measles virus entry inhibitors.

scholarly article
The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity

scientific article
Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists

scientific article
Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties.

scientific article
Synthesis of EF24-tripeptide chloromethyl ketone: a novel curcumin-related anticancer drug delivery system

scientific article published on June 2006
Novel NMDA receptor modulators: an update

scientific article published on September 26, 2012
Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator.

scientific article
Two domains that control prefusion stability and transport competence of the measles virus fusion protein

scientific article published on February 2006
Nonpeptide inhibitors of measles virus entry

scientific article published on August 2006
Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action

scientific article
Dipyrimidine Amines: A Novel Class of Chemokine Receptor Type 4 Antagonists with High Specificity

scientific article published on November 24, 2010
GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity

scientific article
Design of a small-molecule entry inhibitor with activity against primary measles virus strains

scientific article published in September 2005
Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism

scientific article published on 08 October 2009
Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa

scientific article published on 01 April 2008
An Orally Available, Small-Molecule Polymerase Inhibitor Shows Efficacy Against a Lethal Morbillivirus Infection in a Large Animal Model

scientific article published on April 16, 2014
Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects

scientific article
Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy

scientific article published on 06 July 2010
DPC 817: a cytidine nucleoside analog with activity against zidovudine- and lamivudine-resistant viral variants

scientific article published on May 2002
Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators

scientific article
Enigmol: a novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer

scientific article published on 11 March 2011
The Ecstasy and Agony of Assay Interference Compounds

Autophagy and Apoptosis in Hepatocellular Carcinoma Induced by EF25-(GSH)2: A Novel Curcumin Analog

scientific article published on September 30, 2014
Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors

scientific article
NMDA receptor modulators: an updated patent review (2013 – 2014)

scientific article published on October 29, 2014
Directed evolution of an orthogonal nucleoside analog kinase via fluorescence-activated cell sorting

scientific article published on 27 May 2009
Biochemical and mechanistic basis for the activity of nucleoside analogue inhibitors of HIV reverse transcriptase

scientific article published on January 2004
Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties

scientific article published on 23 April 2013
Recent patents regarding the discovery of small molecule CXCR4 antagonists

scientific article published on January 2009
Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators.

scientific article
Multiple Anticancer Activities of EF24, a Novel Curcumin Analog, on Human Ovarian Carcinoma Cells

scientific article published on August 6, 2010
Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis.

scientific article published on 10 January 2015
A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons.

scientific article published on 18 October 2017
CCR5 receptor antagonists in preclinical to phase II clinical development for treatment of HIV.

scientific article published on 28 October 2016
Dynamics and fluidity of amyloid fibrils: a model of fibrous protein aggregates

scientific article published on 01 December 2002
The Ecstasy and Agony of Assay Interference Compounds

scientific article
A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration

scientific article

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