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List of works by Denise Manahan-Vaughan

1S,3R-ACPD dose dependently induces a slow onset potentiation in the dentate gyrus in vivo

scientific article published in December 1995

1S,3R-ACPD dose-dependently induces a slow-onset potentiation in the rat hippocampal CA1 region in vivo

scientific article published in August 1995

5-HT1A receptor-mediated inhibition in the hippocampus of the alert rat — effects of repeated gepirone treatment

scientific article published in August 1994

A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats

scientific article published in January 2008

A specific role for group I mGluRs in hippocampal LTP and hippocampus-dependent spatial learning

scientific article

A specific role for group II metabotropic glutamate receptors in hippocampal long-term depression and spatial memory.

scientific article

ACPD-mediated slow-onset potentiation is associated with cell death in the rat CA1 region in vivo.

scientific article published in April 1999

Activity-dependent switch of GABAergic inhibition into glutamatergic excitation in astrocyte-neuron networks

scientific article published on 24 December 2016

Acute and long-term effects of MK-801 on direct cortical input evoked homosynaptic and heterosynaptic plasticity in the CA1 region of the female rat.

scientific article published in November 2007

Acute intracerebral treatment with amyloid-beta (1-42) alters the profile of neuronal oscillations that accompany LTP induction and results in impaired LTP in freely behaving rats

scientific article published on 6 May 2015

Adaptive changes in 5-HT1A receptor-mediated hippocampal inhibition in the alert rat produced by repeated 8-OH-DPAT treatment.

scientific article published on August 1994

Afferent Input Selects NMDA Receptor Subtype to Determine the Persistency of Hippocampal LTP in Freely Behaving Mice

scientific article published on 21 October 2016

Altered neuronal excitability underlies impaired hippocampal function in an animal model of psychosis

scientific article published on 20 May 2015

An increased expression of the mGlu5 receptor protein following LTP induction at the perforant path-dentate gyrus synapse in freely moving rats.

scientific article

Antagonism of D1/D5 receptors prevents long-term depression (LTD) and learning-facilitated LTD at the perforant path-dentate gyrus synapse in freely behaving rats

scientific article published on 27 August 2014

Antagonism of group III metabotropic glutamate receptors results in impairment of LTD but not LTP in the hippocampal CA1 region, and prevents long-term spatial memory

scientific article published on 29 August 2007

BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment

scientific article published on 28 August 2014

Beta-adrenergic receptors support attention to extinction learning that occurs in the absence, but not the presence, of a context change

scientific article

Beta-adrenoreceptors comprise a critical element in learning-facilitated long-term plasticity

scientific article published on 29 September 2007

Blocking VEGF by Bevacizumab Compromises Electrophysiological and Morphological Properties of Hippocampal Neurons

Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment

scientific article published on April 2016

Brief environmental enrichment elicits metaplasticity of hippocampal synaptic potentiation in vivo

scientific article

Cerebellar-hippocampal processing in passive perception of visuospatial change: An ego- and allocentric axis?

scientific article published on 15 November 2019

Changes in Neuronal Oscillations Accompany the Loss of Hippocampal LTP that Occurs in an Animal Model of Psychosis

scientific article published on 8 March 2017

Correction: MGluR5 Mediates the Interaction between Late-LTP, Network Activity, and Learning.

scientific article published on 28 May 2008

Correction: Pannexin1 Stabilizes Synaptic Plasticity and Is Needed for Learning

scientific article published in PLoS ONE

Defective Synapse Maturation and Enhanced Synaptic Plasticity in Shank2 Δex7–/– Mice.

scientific article published in May 2018

Depotentiation in the dentate gyrus of freely moving rats is modulated by D1/D5 dopamine receptors

scientific article published on June 2000

Differentiation in the protein synthesis-dependency of persistent synaptic plasticity in mossy fiber and associational/commissural CA3 synapses in vivo

scientific article published in March 2013

Distinct Time-Course of Alterations of Groups I and II Metabotropic Glutamate Receptor and GABAergic Receptor Expression Along the Dorsoventral Hippocampal Axis in an Animal Model of Psychosis

Distinct mechanisms of bidirectional activity-dependent synaptic plasticity in superficial and deep layers of rat entorhinal cortex

scientific article published in April 2004

Dopamine D1/D5 receptors contribute to de novo hippocampal LTD mediated by novel spatial exploration or locus coeruleus activity

scientific article published on 29 October 2011

Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression

scientific journal article

Dopamine D1/D5 receptors mediate informational saliency that promotes persistent hippocampal long-term plasticity

scientific article

Dopamine D1/D5, But not D2/D3, Receptor Dependency of Synaptic Plasticity at Hippocampal Mossy Fiber Synapses that Is Enabled by Patterned Afferent Stimulation, or Spatial Learning.

scientific article

Early Loss of Vision Results in Extensive Reorganization of Plasticity-Related Receptors and Alterations in Hippocampal Function That Extend Through Adulthood

article by Mirko Feldmann et al published 1 February 2019 in Cerebral Cortex

Early age-dependent impairments of context-dependent extinction learning, object recognition, and object-place learning occur in rats

scientific article

Editorial: Extinction Learning from a Mechanistic and Systems Perspective

scientific article published on 13 June 2016

Endogenous hippocampal LTD that is enabled by spatial object recognition requires activation of NMDA receptors and the metabotropic glutamate receptor, mGlu5.

scientific article published on 21 September 2012

Event-related potentials evoked by passive visuospatial perception in rats and humans reveal common denominators in information processing

scientific article published on 11 March 2019

Experience-Dependency of Reliance on Local Visual and Idiothetic Cues for Spatial Representations Created in the Absence of Distal Information.

scientific article published on 6 June 2017

Frequency dependency of NMDA receptor-dependent synaptic plasticity in the hippocampal CA1 region of freely behaving mice

scientific article published on 18 June 2012

Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats contributes to the induction of persistent LTD via an adenosine-A1 receptor-regulated mechanism.

scientific article

Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats is regulated by adenosine A1 receptors.

scientific article

Functional Compartmentalization of the Contribution of Hippocampal Subfields to Context-Dependent Extinction Learning

scientific article published on 14 November 2019

Gradient of Expression of Dopamine D2 Receptors Along the Dorso-Ventral Axis of the Hippocampus

scientific article published on 15 October 2019

Group 1 and 2 metabotropic glutamate receptors play differential roles in hippocampal long-term depression and long-term potentiation in freely moving rats

scientific article published in May 1997

Group 1 metabotropic glutamate receptors contribute to slow-onset potentiation in the rat CA1 region in vivo

scientific article published in November 1997

Group I mGlu receptors regulate the expression of the neuronal calcium sensor protein VILIP-1 in vitro and in vivo: implications for mGlu receptor-dependent hippocampal plasticity?

scientific article (publication date: May 2003)

Group I metabotropic glutamate receptors enable two distinct forms of long-term depression in the rat dentate gyrus in vivo

scientific article

Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis

scientific article published in January 2005

Group III metabotropic glutamate receptor-mediated, chemically induced long-term depression differentially affects cell viability in the hippocampus

scientific article

Group III metabotropic glutamate receptors modulate long-term depression in the hippocampal CA1 region of two rat strains in vivo

scientific article published in October 2000

Hippocampal Long-Term Depression as a Declarative Memory Mechanism

Hippocampal Synaptic Plasticity, Spatial Memory, and Neurotransmitter Receptor Expression Are Profoundly Altered by Gradual Loss of Hearing Ability

scientific article published on 20 March 2020

Hippocampal function is compromised in an animal model of multiple sclerosis

scientific article published on 17 March 2015

Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition

scientific article

Hippocampal long-term depression in freely behaving mice requires the activation of beta-adrenergic receptors

scientific article published on 2 September 2013

Hippocampal long-term depression is enhanced, depotentiation is inhibited and long-term potentiation is unaffected by the application of a selective c-Jun N-terminal kinase inhibitor to freely behaving rats.

scientific article published on 31 March 2011

Hippocampal long-term depression is facilitated by the acquisition and updating of memory of spatial auditory content and requires mGlu5 activation

scientific article published on 4 April 2016

Hippocampal long-term depression: master or minion in declarative memory processes?

scientific article

Hippocampal long-term potentiation that is elicited by perforant path stimulation or that occurs in conjunction with spatial learning is tightly controlled by beta-adrenoreceptors and the locus coeruleus.

scientific article

Hippocampal network activity is transiently altered by induction of long-term potentiation in the dentate gyrus of freely behaving rats

scientific article published on 30 December 2007

Hippocampal synaptic metaplasticity requires inhibitory autophosphorylation of Ca2+/calmodulin-dependent kinase II.

scientific article published on August 2005

Identification of a novel signaling pathway and its relevance for GluA1 recycling

scientific article

In the Piriform Cortex, the Primary Impetus for Information Encoding through Synaptic Plasticity Is Provided by Descending Rather than Ascending Olfactory Inputs

scientific article published on 24 November 2017

In vivo electrophysiological investigations into the role of histamine in the dentate gyrus of the rat.

scientific article published in June 1998

Inhibition of the Interaction Between Group I Metabotropic Glutamate Receptors and PDZ-Domain Proteins Prevents Hippocampal Long-Term Depression, but Not Long-Term Potentiation

Intrinsic cellular and molecular properties of in vivo hippocampal synaptic plasticity are altered in the absence of key synaptic matrix molecules

scientific article published on 17 May 2017

Intrinsic, light-independent and visual activity-dependent mechanisms cooperate in the shaping of the field response in rat visual cortex.

scientific article

Investigations of the protein synthesis dependency of mGluR-induced long-term depression in the dentate gyrus of freely moving rats

scientific article published in January 2005

Involvement of Dopamine D1/D5 and D2 Receptors in Context-Dependent Extinction Learning and Memory Reinstatement

scientific article published on January 2015

Involvement of the Postrhinal and Perirhinal Cortices in Microscale and Macroscale Visuospatial Information Encoding

scientific article published on 09 October 2020

Involvement of the metabotropic glutamate receptor mGluR5 in NMDA receptor-dependent, learning-facilitated long-term depression in CA1 synapses

scientific article published on 4 June 2010

Learning-facilitated long-term depression and long-term potentiation at mossy fiber-CA3 synapses requires activation of β-adrenergic receptors

scientific article

Learning-facilitated long-term depression requires activation of the immediate early gene, c-fos, and is transcription dependent

scientific article published on 30 April 2013

Learning-facilitated synaptic plasticity at CA3 mossy fiber and commissural-associational synapses reveals different roles in information processing.

scientific article published on 14 April 2011

Learning-facilitated synaptic plasticity occurs in the intermediate hippocampus in association with spatial learning

scientific article published on 29 October 2013

Less means more: The magnitude of synaptic plasticity along the hippocampal dorso-ventral axis is inversely related to the expression levels of plasticity-related neurotransmitter receptors

scientific article published on 24 November 2017

Lipoprotein receptor loss in forebrain radial glia results in neurological deficits and severe seizures

scientific article published on 24 June 2020

Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors

scientific article published on 23 January 2014

Locus coeruleus activation facilitates memory encoding and induces hippocampal LTD that depends on beta-adrenergic receptor activation.

scientific article published on 11 May 2009

Locus coeruleus: a new look at the blue spot

scientific article published on 17 September 2020

Long-lasting changes in hippocampal synaptic plasticity and cognition in an animal model of NMDA receptor dysfunction in psychosis

scientific article published on 31 January 2013

Long-term depression in freely moving rats is dependent upon strain variation, induction protocol and behavioral state

scientific article published in May 2000

Long-term depression: a cellular basis for learning?

scientific article

Long-term plasticity is proportional to theta-activity

scientific article

Long-term potentiation in vivo increases rat hippocampal tenascin-C expression

scientific article published in November 1998

Loss of Catecholaminergic Neuromodulation of Persistent Forms of Hippocampal Synaptic Plasticity with Increasing Age.

scientific article published on 26 September 2016

MGluR5 mediates the interaction between late-LTP, network activity, and learning

scientific article

MGluRs regulate the expression of neuronal calcium sensor proteins NCS-1 and VILIP-1 and the immediate early gene arg3.1/arc in the hippocampus in vivo

scientific article published in September 2004

Metabotropic glutamate receptor 1 (mGluR1) and 5 (mGluR5) regulate late phases of LTP and LTD in the hippocampal CA1 region in vitro

scientific article published in March 2008

Metabotropic glutamate receptor agonist trans-azetidine-2,4-dicarboxylic acid facilitates maintenance of LTP in the dentate gyrus in vivo

scientific article published in August 1995

Metabotropic glutamate receptor subtype agonists facilitate long-term potentiation within a distinct time window in the dentate gyrus in vivo

scientific article published in October 1996

Metabotropic glutamate receptor, mGlu5, mediates enhancements of hippocampal long-term potentiation after environmental enrichment in young and old mice

scientific article

Metabotropic glutamate receptor, mGlu5, regulates hippocampal synaptic plasticity and is required for tetanisation-triggered changes in theta and gamma oscillations

scientific article published on 6 July 2016

Metabotropic glutamate receptors, 5 years on

scientific article published in March 2017

Metaplastic contribution of Neuropeptide Y receptors to spatial memory acquisition

scientific article published on 19 August 2020

MicroRNAs contribute to LTP in the hippocampus in vivo (Commentary on Wibrand et al.).

scientific article published in February 2010

Modulation by group 1 metabotropic glutamate receptors of depotentiation in the dentate gyrus of freely moving rats

scientific article published in January 2008

Modulation by serotonin 5-HT(4) receptors of long-term potentiation and depotentiation in the dentate gyrus of freely moving rats

scientific article

Modulation of hippocampus-prefrontal cortex synaptic transmission and disruption of executive cognitive functions by MK-801.

scientific article published on 4 December 2013

NMDA receptor-dependent synaptic plasticity in dorsal and intermediate hippocampus exhibits distinct frequency-dependent profiles

scientific article published on 13 March 2013

Neurodegeneration and energy metabolism: from chemistry to clinics

scientific article

Novel encoding and updating of positional, or directional, spatial cues are processed by distinct hippocampal subfields: evidence for parallel information processing and the "what" stream

scientific article published on 2 February 2018

Novelty acquisition is associated with induction of hippocampal long-term depression.

scientific article published on July 1999

Optogenetic modulation and multi-electrode analysis of cerebellar networks in vivo

scientific article

Orchestration of Hippocampal Information Encoding by the Piriform Cortex

scientific article published on 01 January 2020

PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis

scientific article

Pannexin1 stabilizes synaptic plasticity and is needed for learning

scientific article

Passive spatial perception facilitates the expression of persistent hippocampal long-term depression

scientific article published on 13 September 2011

Persistent (>24h) long-term depression in the dentate gyrus of freely moving rats is not dependent on activation of NMDA receptors, L-type voltage-gated calcium channels or protein synthesis

scientific article published on 8 August 2006

Persistent deficits in hippocampal synaptic plasticity accompany losses of hippocampus-dependent memory in a rodent model of psychosis

scientific article published on 15 March 2013

Pharmacological antagonism of metabotropic glutamate receptor 1 regulates long-term potentiation and spatial reference memory in the dentate gyrus of freely moving rats via N-methyl-D-aspartate and metabotropic glutamate receptor-dependent mechanism

scientific article published on January 2005

Physiological and pharmacological profile oftrans-azetidine-2,4-dicarboxylic acid: Metabotropic glutamate receptor agonism and effects on long-term potentiation

scientific article published in June 1996

Place field stability requires the metabotropic glutamate receptor, mGlu5.

scientific article published on 25 June 2014

Preferential frequency‐dependent induction of synaptic depression by the lateral perforant path and of synaptic potentiation by the medial perforant path inputs to the dentate gyrus

scientific article published in 2021

Presynaptic group 1 metabotropic glutamate receptors may contribute to the expression of long-term potentiation in the hippocampal CA1 region

scientific article published in September 1999

Priming of group 2 metabotropic glutamate receptors facilitates induction of long-term depression in the dentate gyrus of freely moving rats.

scientific article

Protein trafficking, targeting, and interaction at the glutamate synapse

scientific article published on 13 November 2008

Ras does not contribute to the facilitation of hippocampal synaptic plasticity enabled by environmental enrichment

scientific article

Regional and developmental profile of modulation of hippocampal synaptic transmission and LTP by AP4-sensitive mGluRs in vivo

scientific article published in August 1995

Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: relevance for learning and memory formation

scientific article published on February 2004

Regulation of depotentiation and long-term potentiation in the dentate gyrus of freely moving rats by dopamine D2-like receptors

scientific article published on February 2003

Regulation of hippocampal synaptic plasticity thresholds and changes in exploratory and learning behavior in dominant negative NPR-B mutant rats.

scientific article

Regulation of long-term depression by increases in [guanosine 3',5'-cyclic monophosphate] in the hippocampal CA1 region of freely behaving rats

scientific article published on 7 April 2008

Relationship of hippocampal theta and gamma oscillations to potentiation of synaptic transmission

scientific article published on 7 July 2008

Requirement of translation but not transcription for the maintenance of long-term depression in the CA1 region of freely moving rats

scientific article published on 15 November 2000

Rescue of hippocampal LTP and learning deficits in a rat model of psychosis by inhibition of glycine transporter-1 (GlyT1).

scientific article published in October 2008

Role of inhibitory autophosphorylation of calcium/calmodulin-dependent kinase II (αCAMKII) in persistent (>24 h) hippocampal LTP and in LTD facilitated by novel object-place learning and recognition in mice

scientific article published on 27 January 2014

Role of metabotropic glutamate receptors in persistent forms of hippocampal plasticity and learning

scientific article published on 26 June 2012

Role of the group III metabotropic glutamate receptor in LTP, depotentiation and LTD in dentate gyrus of freely moving rats

scientific article published on February 2004

Semi-automated analysis of NMDA-mediated toxicity in digitised colour images from rat hippocampus

scientific article published in July 1998

Spatial object recognition enables endogenous LTD that curtails LTP in the mouse hippocampus

scientific article published on 17 April 2012

Spatial olfactory learning contributes to place field formation in the hippocampus

scientific article

Spatial olfactory learning facilitates long-term depression in the hippocampus

scientific article published on 19 July 2013

Spatial representations of place cells in darkness are supported by path integration and border information

scientific article

Strain-dependent variations in spatial learning and in hippocampal synaptic plasticity in the dentate gyrus of freely behaving rats

scientific article published on 7 March 2011

Subtype-specific involvement of metabotropic glutamate receptors in two forms of long-term potentiation in the dentate gyrus of freely moving rats

scientific article published in October 1998

Synaptic depression in the CA1 region of freely behaving mice is highly dependent on afferent stimulation parameters

scientific article published on 25 January 2013

Synaptic plasticity from visual cortex to hippocampus: systems integration in spatial information processing.

scientific article published on 08 July 2008

Synaptic plasticity in the adult visual cortex is regulated by the metabotropic glutamate receptor, mGluR5.

scientific article published in December 2009

Synaptic strength at the temporoammonic input to the hippocampal CA1 region in vivo is regulated by NMDA receptors, metabotropic glutamate receptors and voltage-gated calcium channels

scientific article published on 17 March 2015

The 5-hydroxytryptamine4 receptor enables differentiation of informational content and encoding in the hippocampus.

scientific article

The 5-hydroxytryptamine4 receptor exhibits frequency-dependent properties in synaptic plasticity and behavioural metaplasticity in the hippocampal CA1 region in vivo

scientific article published on 10 November 2004

The adult visual cortex expresses dynamic synaptic plasticity that is driven by the light/dark cycle.

scientific article

The azapirone metabolite 1-(2-pyrimidinyl)piperazine depresses excitatory synaptic transmission in the hippocampus of the alert rat via 5-HT1A receptors

scientific article

The hippocampal CA1 region and dentate gyrus differentiate between environmental and spatial feature encoding through long-term depression

scientific article published on 16 August 2007

The metabotropic glutamate receptor mGluR3 is critically required for hippocampal long-term depression and modulates long-term potentiation in the dentate gyrus of freely moving rats

scientific article published on 5 January 2005

The metabotropic glutamate receptor, mGlu5, is required for extinction learning that occurs in the absence of a context change

scientific article published on 30 September 2014

The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity

scientific article

The neuronal EF-hand calcium-binding protein visinin-like protein-3 is expressed in cerebellar Purkinje cells and shows a calcium-dependent membrane association

scientific article (publication date: 2000)

The requirement of BDNF for hippocampal synaptic plasticity is experience-dependent

scientific article published on 10 December 2015

The serotonergic 5-HT4 receptor: A unique modulator of hippocampal synaptic information processing and cognition

scientific article published on 15 June 2016

The temporoammonic input to the hippocampal CA1 region displays distinctly different synaptic plasticity compared to the Schaffer collateral input in vivo: significance for synaptic information processing

scientific article published on 23 August 2013

Time-Dependent Alterations in the Expression of NMDA Receptor Subunits along the Dorsoventral Hippocampal Axis in an Animal Model of Nascent Psychosis

scientific article published on 10 April 2018

Time-dependent induction of depotentiation in the dentate gyrus of freely moving rats: involvement of group 2 metabotropic glutamate receptors

scientific article published in November 1999

Visual cortex plasticity evokes excitatory alterations in the hippocampus.

scientific article published on 23 November 2009

mGlu5 acts as a switch for opposing forms of synaptic plasticity at mossy fiber-CA3 and commissural associational-CA3 synapses.

scientific article published on March 2015

β-Adrenergic Control of Hippocampal Function: Subserving the Choreography of Synaptic Information Storage and Memory.

scientific article

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