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List of works by Changmeng Cai

A novel nonsense mutation in androgen receptor confers resistance to CYP17 inhibitor treatment in prostate cancer

scientific article published on 27 December 2016

Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation.

scientific article published on 2 December 2011

Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein.

scientific article published on October 2016

Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells

scientific article published on 26 September 2006

Androgen receptor epigenetics.

scientific article published on September 2013

Androgen receptor expression in prostate cancer cells is suppressed by activation of epidermal growth factor receptor and ErbB2.

scientific article

Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis

scientific article published on 10 June 2013

Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.

scientific article published on October 2011

Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation.

scientific article published on 24 January 2012

BMX-Mediated Regulation of Multiple Tyrosine Kinases Contributes to Castration Resistance in Prostate Cancer

scientific article published on 16 July 2018

Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer

scientific article published on 31 August 2020

Discovery of a selective irreversible BMX inhibitor for prostate cancer.

scientific article published on 26 April 2013

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

scientific article published on 15 February 2013

ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion.

scientific article published on 15 May 2007

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent

scientific article

ErbB2 Signaling Increases Androgen Receptor Expression in Abiraterone-Resistant Prostate Cancer

scientific article published on 2 March 2016

Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155.

scientific article published in May 2017

Expression of a hyperactive androgen receptor leads to androgen-independent growth of prostate cancer cells.

scientific article

Forkhead domain mutations in FOXA1 drive prostate cancer progression

scientific article published on 19 July 2019

Galeterone prevents androgen receptor binding to chromatin and enhances degradation of mutant androgen receptor.

scientific article published on 29 May 2014

In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer

scientific article

Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy ⬇️

scientific article published on August 30, 2011

Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors ⬇️

scientific article published on August 25, 2011

LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression.

scientific article

Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity.

scientific article

Makorin RING finger protein 1 (MKRN1) has negative and positive effects on RNA polymerase II-dependent transcription

scientific article published in April 2006

PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy

scientific article published on 25 March 2015

Pioneer of prostate cancer: past, present and the future of FOXA1

scientific article published on 18 September 2020

Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer

scientific article published on 6 January 2017

Protein phosphatase 1 suppresses androgen receptor ubiquitylation and degradation

scientific article published on 30 November 2015

Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer.

scientific article published on 21 January 2014

Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer

scientific article

Reactivation of androgen receptor-regulated lipid biosynthesis drives the progression of castration-resistant prostate cancer.

scientific article published on 23 October 2017

SOX9 drives WNT pathway activation in prostate cancer

scientific article published on 04 April 2016

SUMO-3 enhances androgen receptor transcriptional activity through a sumoylation-independent mechanism in prostate cancer cells.

scientific article published on 15 December 2005

Soluble Guanylyl Cyclase α1 and p53 Cytoplasmic Sequestration and Down-Regulation in Prostate Cancer ⬇️

scientific article published on December 15, 2011

TMPRSS2-ERG activates NO-cGMP signaling in prostate cancer cells

scientific article published on 04 February 2019

Tyrosine kinase BMX phosphorylates phosphotyrosine-primed motif mediating the activation of multiple receptor tyrosine kinases

scientific article

c-Jun has multiple enhancing activities in the novel cross talk between the androgen receptor and Ets variant gene 1 in prostate cancer

scientific article published on 01 July 2007

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