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List of works by Mingjie Zhang

A Peptide Corresponding to Residues Asp177 to Asn208 of Human Cyclin A Forms an α-Helix

scientific article published in 1998

A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function

scientific article published on 16 May 2016

A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses

scientific article

A structural approach to decipher the neurexin and neuroligin splice isoform code

scientific article published on July 2010

A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins

scientific article

Activator of G protein signaling 3 forms a complex with resistance to inhibitors of cholinesterase-8A without promoting nucleotide exchange on Gα(i3).

scientific article

Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase

scientific article published on 14 January 2016

An Atypical MAGUK GK Target Recognition Mode Revealed by the Interaction between DLG and KIF13B

scientific article

An Exquisitely Specific PDZ/Target Recognition Revealed by the Structure of INAD PDZ3 in Complex with TRP Channel Tail

scientific article

An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs

scientific article

An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p

scientific article

An unexpected INAD PDZ tandem-mediated plcβ binding in photo receptors

scientific article published on 10 December 2018

Anchoring high concentrations of SynGAP at postsynaptic densities via liquid-liquid phase separation.

scientific article published on 19 May 2017

Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway

scientific article

Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic β cell insufficiency

scientific article published on 13 July 2015

Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP

scientific article published on 30 November 2018

Antiparallel coiled-coil-mediated dimerization of myosin X

scientific article

Apoptosis-Linked Gene Product ALG-2 Is a New Member of the Calpain Small Subunit Subfamily of Ca2+-Binding Proteins†

article

Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23

scientific article

Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor

scientific article

Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem

scientific article

Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions

scientific article published on 25 August 2017

BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway

scientific article

Backbone dynamics of the 8 kDa dynein light chain dimer reveals molecular basis of the protein's functional diversity.

scientific article published in June 2002

Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division

scientific article published on 21 February 2018

Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain

scientific article published on November 2002

Ca2+-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single α Helix Lever Arm Extension

scientific article published on 24 February 2017

CaMKIIα-driven, phosphatase-checked postsynaptic plasticity via phase separation

scientific article published on 24 November 2020

Calcium-induced conformational transition revealed by the solution structure of apo calmodulin

scientific article

Cargo recognition and cargo-mediated regulation of unconventional myosins

scientific article published on 17 September 2014

Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain

scientific article

Cdc42-dependent formation of the ZO-1/MRCKβ complex at the leading edge controls cell migration

scientific article

Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes

scientific article

Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes.

scientific article published in February 2009

Combination of NMR spectroscopy and X-ray crystallography offers unique advantages for elucidation of the structural basis of protein complex assembly

scientific article

Correction: Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP

scientific article published on 31 January 2019

Creating conformational entropy by increasing interdomain mobility in ligand binding regulation: a revisit to N-terminal tandem PDZ domains of PSD-95

scientific article

Crystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Gαi

scientific journal article

Cyclin-dependent Kinase 5 (Cdk5) Activation Domain of Neuronal Cdk5 Activator

scientific article published in Journal of Biological Chemistry

DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis.

scientific article published in November 2017

DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis.

scientific article published in December 2017

Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity

scientific article published on 05 September 2019

Decorating proteins with "sweets" is a flexible matter

scientific article

Distinguishing between smooth and rough free energy barriers in protein folding.

scientific article

Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites

scientific article

Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia

scientific article

Effect of alpha-domain substitution on the structure, property and function of human neuronal growth inhibitory factor

scientific article

Electroporation of micro-droplet encapsulated HeLa cells in oil phase

scientific article published on 01 September 2010

Endophilin B1 as a novel regulator of nerve growth factor/ TrkA trafficking and neurite outgrowth.

scientific article published in September 2008

Extensions of PDZ domains as important structural and functional elements

scientific article

Flavonoids from Radix Scutellariae as potential stroke therapeutic agents by targeting the second postsynaptic density 95 (PSD-95)/disc large/zonula occludens-1 (PDZ) domain of PSD-95.

scientific article

Formation of a native-like beta-hairpin finger structure of a peptide from the extended PDZ domain of neuronal nitric oxide synthase in aqueous solution

scientific article

Gephyrin-mediated formation of inhibitory postsynaptic density sheet via phase separation

scientific article published on 02 November 2020

Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules

scientific article

Human tRNA synthetase catalytic nulls with diverse functions

scientific article

IL-1β and reactive oxygen species differentially regulate neutrophil directional migration and Basal random motility in a zebrafish injury-induced inflammation model

scientific article published on 16 May 2014

Identification and structure characterization of a Cdk inhibitory peptide derived from neuronal-specific Cdk5 activator

scientific article

Identification of a common protein association region in the neuronal Cdk5 activator

scientific article

Identification of the yeast R-SNARE Nyv1p as a novel longin domain-containing protein

scientific article

Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG

scientific article

In silico whole-genome scanning of cancer-associated nonsynonymous SNPs and molecular characterization of a dynein light chain tumour variant.

scientific article

Interaction of calmodulin with its binding domain of rat cerebellar nitric oxide synthase. A multinuclear NMR study

scientific journal article

Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing

scientific article

Isotope-Edited Fourier Transform Infrared Spectroscopy Studies of Calmodulin's Interaction with Its Target Peptides

scientific article published on 01 September 1994

LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways

scientific article

Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia

scientific article

Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain

scientific article

Lipid binding regulates synaptic targeting of PICK1, AMPA receptor trafficking, and synaptic plasticity.

scientific article published in March 2006

Lipid-Induced conformational switch controls fusion activity of longin domain SNARE Ykt6

scientific article

Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures

scientific article

Mechanisms of MAGUK-mediated cellular junctional complex organization

scientific article published on 13 September 2017

Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex

scientific article

Mechanistic basis of MAGUK-organized complexes in synaptic development and signalling

scientific article published on March 2016

Membrane-induced lever arm expansion allows myosin VI to walk with large and variable step sizes

scientific article

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

scientific article

Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1

scientific article

Mutation at Glu23 eliminates the neuron growth inhibitory activity of human metallothionein-3

scientific article

Myosin VI undergoes cargo-mediated dimerization

scientific article

NMR structure of a type IVb pilin from Salmonella typhi and its assembly into pilus

scientific article

NMR studies of the methionine methyl groups in calmodulin

scientific article published on 01 June 1995

Neuronal Synapses: Microscale Signal Processing Machineries Formed by Phase Separation?

scientific article published on 12 April 2018

Novel Variant in the ANK2 Membrane-Binding Domain Is Associated With Ankyrin-B Syndrome and Structural Heart Disease in a First Nations Population With a High Rate of Long QT Syndrome

scientific article published in January 2017

Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density

scientific article published on February 2009

Organization of signaling complexes by PDZ-domain scaffold proteins

scientific article

Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding

scientific article

PDZ Ligand Binding-Induced Conformational Coupling of the PDZ-SH3-GK Tandems in PSD-95 Family MAGUKs

scientific article published on 11 November 2017

PDZ domains of Par-3 as potential phosphoinositide signaling integrators

scientific article

PDZ7 of glutamate receptor interacting protein binds to its target via a novel hydrophobic surface area

scientific article

Par complex cluster formation mediated by phase separation

scientific article published on 08 May 2020

Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment

scientific journal article

Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity

scientific article

Phase separation at the synapse

scientific article published on 03 February 2020

Phosphorylation of DCC by ERK2 is facilitated by direct docking of the receptor P1 domain to the kinase

scientific article

Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl

scientific article

Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins

scientific article published on 04 June 2018

Pressure Sensitivity of SynGAP/PSD-95 Condensates as a Model for Postsynaptic Densities and its Biophysical and Neurological Ramifications

scientific article published on 07 January 2020

Proteasome-independent polyubiquitin linkage regulates synapse scaffolding, efficacy, and plasticity.

scientific article

Protein Complex Assemblies in Epithelial Cell Polarity and Asymmetric Cell Division

scientific article published on 26 September 2017

Protein engineering and NMR studies of calmodulin

scientific article published on 01 August 1995

Protein inhibitor of neuronal nitric-oxide synthase, PIN, binds to a 17-amino acid residue fragment of the enzyme

scientific article

Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP.

scientific article

Redox-regulated lipid membrane binding of the PICK1 PDZ domain

scientific article

Reductive methylation andpKa determination of the lysine side chains in calbindin D9k

scientific article published on 01 August 1994

Regulated capture by exosomes of mRNAs for cytoplasmic tRNA synthetases

scientific article published on 03 September 2013

Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity

scientific article published on 27 December 2012

Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice

scientific article

Rigidified clicked dimeric ligands for studying the dynamics of the PDZ1-2 supramodule of PSD-95.

scientific article

Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression

scientific article

SAP97 Binding Partner CRIPT Promotes Dendrite Growth In Vitro and In Vivo.

scientific article published in November 2017

Scaffold proteins as dynamic switches

Secreted histidyl-tRNA synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis

scientific article

Self-assembly of small molecules affords multifunctional supramolecular hydrogels for topically treating simulated uranium wounds

scientific article published on 3 August 2005

Serine 88 phosphorylation of the 8-kDa dynein light chain 1 is a molecular switch for its dimerization status and functions

scientific article published on 14 December 2007

Signaling complex organization by PDZ domain proteins

scientific article

Site Selective Azo Coupling for Peptide Cyclization and Affinity Labeling of an SH3 Protein

scientific article published on 2 July 2015

Site-Specific Phosphorylation of PSD-95 PDZ Domains Reveals Fine-Tuned Regulation of Protein-Protein Interactions

scientific article published on 10 July 2017

Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95

scientific article

Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95

Solution structure of a protein inhibitor of neuronal nitric oxide synthase

scientific article

Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide

scientific article

Specific Eph Receptor-Cytoplasmic Effector Signaling Mediated by SAM-SAM Domain Interactions

Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.

scientific article

Spectroscopic Characterization of a High-Affinity Calmodulin−Target Peptide Hybrid Molecule†

scientific article published in 1996

Split pleckstrin homology domain-mediated cytoplasmic-nuclear localization of PI3-kinase enhancer GTPase

scientific article

Structural Basis of Cargo Recognition by Unconventional Myosins in Cellular Trafficking

scientific article published on 4 February 2016

Structural Basis of the Binding of Merlin FERM Domain to the E3 Ubiquitin Ligase Substrate Adaptor DCAF1

scientific article

Structural and biochemical characterization of the interaction between LGN and Frmpd1

scientific article

Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin

scientific article

Structural basis of GABARAP-mediated GABA<sub>A</sub> receptor trafficking and functions on GABAergic synaptic transmission

scientific article published on 12 January 2021

Structural basis of cargo recognitions for class V myosins

scientific article

Structural basis of diverse membrane target recognitions by ankyrins

scientific article

Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain

scientific article

Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor

scientific article

Structural characterization of the split pleckstrin homology domain in phospholipase C-gamma1 and its interaction with TRPC3.

scientific article

Structural insights into the intrinsic self-assembly of Par-3 N-terminal domain

scientific article

Structural prediction of the β-domain of metallothionein-3 by molecular dynamics simulation

article

Structure and function of the guanylate kinase-like domain of the MAGUK family scaffold proteins

Structure basis and unconventional lipid membrane binding properties of the PH-C1 tandem of rho kinases

scientific article

Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex

scientific article published on 10 November 2014

Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo

scientific article

Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins.

scientific article published on 24 April 2017

Structure of Tctex-1 and its interaction with cytoplasmic dynein intermediate chain

scientific journal article

Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling

scientific article published in December 2014

Structure of the ZU5-ZU5-UPA-DD tandem of ankyrin-B reveals interaction surfaces necessary for ankyrin function

scientific article

Structure of the monomeric 8-kDa dynein light chain and mechanism of the domain-swapped dimer assembly

scientific article

Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin

scientific article

Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures

scientific article published on October 2013

Structures of usher syndrome 1 proteins and their complexes

scientific article

Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKCι in complex with a substrate peptide from Par-3

scientific article

Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1

scientific article

Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95

scientific article (publication date: 14 March 2003)

Synaptic PDZ domain-mediated protein interactions are disrupted by inhalational anesthetics

scientific article

Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs

scientific article published in December 2017

Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding

scientific article

Targeting PDZ domain proteins for treating NMDA receptor-mediated excitotoxicity.

scientific article published in January 2006

The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif

scientific article (publication date: 27 April 2001)

The 8-kDa dynein light chain binds to p53-binding protein 1 and mediates DNA damage-induced p53 nuclear accumulation

scientific article

The BECN1 coiled coil domain: an "imperfect" homodimer interface that facilitates ATG14 and UVRAG binding

scientific article published on 31 May 2012

The CC1-FHA tandem as a central hub for controlling the dimerization and activation of kinesin-3 KIF1A

scientific article

The Calmodulin-Binding Domain of Caldesmon Binds to Calmodulin in an .alpha.-Helical Conformation

scientific article published on 01 February 1994

The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye

scientific article

The Par-3 NTD adopts a PB1-like structure required for Par-3 oligomerization and membrane localization

scientific article

The Par3/Par6/aPKC complex and epithelial cell polarity

scientific article published on 25 March 2013

The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin

scientific article

The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase

scientific article

The effect of the EAAEAE insert on the property of human metallothionein-3.

scientific article published in December 2003

The effects of germanium addition on properties of Ga-Sb-S chalcogenide glasses

article

The role of Thr5 in human neuron growth inhibitory factor

scientific article

The structural basis of Miranda-mediated Staufen localization during Drosophila neuroblast asymmetric division.

scientific article

The structure of the PDZ3-SH3-GuK tandem of ZO-1 protein suggests a supramodular organization of the membrane-associated guanylate kinase (MAGUK) family scaffold protein core

scientific article published on 29 September 2011

The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins

scientific article

The tetrameric L27 domain complex as an organization platform for supramolecular assemblies

scientific article

Two-dimensional NMR studies of selenomethionyl calmodulin.

scientific article

Unexpected Heterodivalent Recruitment of NOS1AP to nNOS Reveals Multiple Sites for Pharmacological Intervention in Neuronal Disease Models.

scientific article

Versatile Site-Selective Protein Reaction Guided by WW Domain-Peptide Motif Interaction

scientific article published on 12 July 2017

p150(Glued), Dynein, and microtubules are specifically required for activation of MKK3/6 and p38 MAPKs

scientific article

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