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List of works by Koji Oba

A Comparison of the Effects of the GLP-1 Analogue Liraglutide and Insulin Glargine on Endothelial Function and Metabolic Parameters: A Randomized, Controlled Trial Sapporo Athero-Incretin Study 2 (SAIS2).

scientific article published on 18 August 2015

A Phase II Study of XELOX and Cetuximab as First-Line Therapy in Patients With KRAS Wild Type Metastatic Colorectal Cancer (FLEET2 Study).

scientific article

A Randomized Controlled Trial Comparing the Effects of Sitagliptin and Glimepiride on Endothelial Function and Metabolic Parameters: Sapporo Athero-Incretin Study 1 (SAIS1).

scientific article

A new prognostic classification for overall survival in Asian patients with previously untreated metastatic renal cell carcinoma

scientific article published on 11 July 2012

A novel system for predicting the toxicity of irinotecan based on statistical pattern recognition with UGT1A genotypes.

scientific article

A phase I study of palliative chemoradiation therapy with paclitaxel and cisplatin for local symptoms due to an unresectable primary advanced or locally recurrent gastric adenocarcinoma

scientific article

A phase II trial to evaluate the efficacy of panitumumab combined with fluorouracil-based chemotherapy for metastatic colorectal cancer: the PF trial

scientific article published on 5 March 2018

A prospective analysis of clinical efficacy and safety in chronic myeloid leukemia-chronic phase patients with imatinib resistance or intolerance as evaluated using European LeukemiaNet 2013 criteria

scientific article published on 19 February 2015

A prospective, multicenter survey on the validity of shorter periendoscopic cessation of antithrombotic agents in Japan

scientific article published on 16 April 2016

Acute hemodynamic effects of adaptive servo-ventilation in patients with heart failure

scientific article published on 30 January 2013

Adaptive Servo-Ventilation Has More Favorable Acute Effects on Hemodynamics Than Continuous Positive Airway Pressure in Patients With Heart Failure.

scientific article published on 11 September 2015

An individual patient data meta-analysis of adjuvant therapy with uracil-tegafur (UFT) in patients with curatively resected rectal cancer.

scientific article

Assessing clinical benefit response in the treatment of gastric malignant ascites with non-measurable lesions: a multicenter phase II trial of paclitaxel for malignant ascites secondary to advanced/recurrent gastric cancer

scientific article published on 17 February 2011

Associations between visceral obesity and renal impairment in health checkup participants: a retrospective cohort study

scientific article published on 01 July 2020

Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis

scientific article published on May 2010

Capecitabine and oxaliplatin combined with bevacizumab are feasible for treating selected Japanese patients at least 75 years of age with metastatic colorectal cancer.

scientific article published on 24 October 2015

Cardiac magnetic resonance performs better in the detection of functionally significant coronary artery stenosis compared to single-photon emission computed tomography and dobutamine stress echocardiography.

scientific article

Clinical Efficacy and Safety of First-Line Dasatinib Therapy and the Relevance of Velocity of BCR-ABL1 Transcript Decline for Achievement of Molecular Responses in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia: Report from the Juntendo Yama

scientific article published on 18 November 2017

Clinical effectiveness of four neuraminidase inhibitors (oseltamivir, zanamivir, laninamivir, and peramivir) for children with influenza A and B in the 2014-2015 to 2016-2017 influenza seasons in Japan

scientific article published on 24 February 2018

Clinical impact of tumor location on the colon cancer survival and recurrence: analyses of pooled data from three large phase III randomized clinical trials.

scientific article published on 25 September 2017

Clinical significance of left ventricular hypertrophy and changes in left ventricular mass in high-risk hypertensive patients: a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan trial.

scientific article published in August 2009

Clinical significance of serum tumor markers for gastric cancer: a systematic review of literature by the Task Force of the Japanese Gastric Cancer Association.

scientific article published on 10 April 2013

Comparison of Different Symptom Assessment Scales for Multiple System Atrophy

scientific article published on 21 June 2015

Comparison of Targeted vs Random Biopsies for Surveillance of Ulcerative Colitis-Associated Colorectal Cancer.

scientific article published on 11 August 2016

Comparison of the clinical effectiveness of zanamivir and laninamivir octanoate for children with influenza A(H3N2) and B in the 2011-2012 season

scientific article

Decreased serum brain-derived neurotrophic factor levels are correlated with exercise intolerance in patients with heart failure

scientific article

Development and Validation of a Prediction Model for Postoperative Peritoneal Metastasis After Curative Resection of Colon Cancer

scientific article published on 05 March 2018

Development and validation of a prognostic nomogram for colorectal cancer after radical resection based on individual patient data from three large-scale phase III trials

scientific article published on 12 October 2017

Diamine oxidase as a marker of intestinal mucosal injury and the effect of soluble dietary fiber on gastrointestinal tract toxicity after intravenous 5-fluorouracil treatment in rats.

scientific article published on 5 September 2013

Differences in UGT1A1, UGT1A7, and UGT1A9 polymorphisms between Uzbek and Japanese populations

scientific article

Disease-free survival as a surrogate for overall survival in adjuvant trials of gastric cancer: a meta-analysis

scientific article

Does a laparoscopic approach attenuate the body weight loss and lean body mass loss observed in open distal gastrectomy for gastric cancer? a single-institution exploratory analysis of the JCOG 0912 phase III trial.

scientific article published on 16 June 2017

Does remnant gastric cancer really differ from primary gastric cancer? A systematic review of the literature by the Task Force of Japanese Gastric Cancer Association.

scientific article published on 14 December 2015

Effect of antispasmodic drugs on endoscopic ultrasound/endoscopic ultrasound-guided fine-needle aspiration: A multicenter randomized controlled trial

scientific article published on July 2014

Effects of KIR ligand incompatibility on clinical outcomes of umbilical cord blood transplantation without ATG for acute leukemia in complete remission

scientific article

Effects of candesartan compared with amlodipine in hypertensive patients with high cardiovascular risks: candesartan antihypertensive survival evaluation in Japan trial.

scientific article published on 2 January 2008

Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curative resections of gastric cancer.

scientific article

Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curatively resected colorectal cancer: a meta-analysis of centrally randomized controlled clinical trials.

scientific article

Efficacy of corticosteroids for cancer-related fatigue: A pilot randomized placebo-controlled trial of advanced cancer patients.

scientific article published on 5 November 2014

Efficacy of oral anticancer agents for colorectal cancer.

scientific article

Erratum to: The COMET Open-label Phase II Study of Neoadjuvant FOLFOX or XELOX Treatment Combined with Molecular Targeting Monoclonal Antibodies in Patients with Resectable Liver Metastasis of Colorectal Cancer

scientific article published on 01 December 2016

FOLFIRI Plus Bevacizumab 5 mg/kg Versus 10 mg/kg as Second-line Therapy in Patients with Metastatic Colorectal Cancer Who Have Failed First-line Bevacizumab Plus Oxaliplatin-based Therapy: A Randomized Phase III Study (EAGLE Study) ⬇️

scientific article published on December 12, 2011

FOLFIRI plus bevacizumab as second-line therapy in patients with metastatic colorectal cancer after first-line bevacizumab plus oxaliplatin-based therapy: the randomized phase III EAGLE study.

scientific article published on 23 April 2015

Geographic difference in advanced gastric cancer prevalence and chemotherapy treatment results: could it really be an independent prognostic factor?

scientific article published on 01 July 2012

Hazard rate of tumor recurrence over time in patients with colon cancer: implications for postoperative surveillance from three Japanese Foundation for Multidisciplinary Treatment of Cancer (JFMC) clinical trials.

scientific article published on 23 October 2017

Higher Hemoglobin A1c After Discharge Is an Independent Predictor of Adverse Outcomes in Patients With Acute Coronary Syndrome　- Findings From the PACIFIC Registry

scientific article published on 19 May 2016

How to use marginal structural models in randomized trials to estimate the natural direct and indirect effects of therapies mediated by causal intermediates.

scientific article

Immunohistochemical validation and expression profiling of NKG2D ligands in a wide spectrum of human epithelial neoplasms

scientific article published on 3 December 2014

Impact of left ventricular hypertrophy on the time-course of renal function in hypertensive patients – a subanalysis of the CASE-J trial –.

scientific article published on 21 August 2010

Impact of postoperative complications on the colorectal cancer survival and recurrence: analyses of pooled individual patients' data from three large phase III randomized trials.

scientific article

Influence of coronary risk factors on coronary events in Japanese high-risk hypertensive patients. - Primary and secondary prevention of ischemic heart disease in a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J

scientific article

Initial safety report on the tolerability of modified FOLFOX6 as adjuvant therapy in patients with curatively resected stage II or III colon cancer (JFMC41-1001-C2: JOIN trial)

scientific article published on 16 May 2015

Is Memorial Sloan-Kettering Cancer Center risk classification appropriate for Japanese patients with metastatic renal cell carcinoma in the cytokine era?

scientific article published on 29 September 2011

Long-term effects of candesartan and amlodipine on cardiovascular morbidity and mortality in Japanese high-risk hypertensive patients: the Candesartan Antihypertensive Survival Evaluation in Japan Extension Study (CASE-J Ex) ⬇️

scientific article published on August 11, 2011

Long-term effects of candesartan and amlodipine on cardiovascular mortality and morbidity in Japanese high-risk hypertensive patients: rationale, design, and characteristics of candesartan antihypertensive survival evaluation in Japan extension (CAS

scientific article published on 13 September 2008

Long-term outcome in Japanese patients with lupus nephritis.

scientific article

Longitudinal comparison of quality of life after real-time tumor-tracking intensity-modulated radiation therapy and radical prostatectomy in patients with localized prostate cancer

scientific article published on 9 May 2013

Lymph node retrieval after dissolution of surrounding adipose tissue for pathological examination of colorectal cancer.

scientific article published on 14 December 2017

Meta-analysis of randomized clinical trials in the era of individual patient data sharing

scientific article published on 12 January 2018

Multicenter Phase II study of FOLFOX or biweekly XELOX and Erbitux (cetuximab) as first-line therapy in patients with wild-type KRAS/BRAF metastatic colorectal cancer: The FLEET study.

scientific article published on 14 October 2015

Multicenter phase II study of infusional 5-fluorouracil (5-FU), leucovorin, and oxaliplatin, plus biweekly cetuximab as first-line treatment in patients with metastatic colorectal cancer (CELINE trial).

scientific article published on 14 December 2016

Multicenter phase II trial of combination chemotherapy with weekly paclitaxel and 5-fluorouracil for the treatment of advanced or recurrent gastric carcinoma

scientific article published on 01 August 2007

Multicenter randomized controlled study to assess the effect of prophylactic clipping on post-polypectomy delayed bleeding.

scientific article published on 25 May 2016

Multicenter randomized phase II clinical trial of oxaliplatin reintroduction as a third- or later-line therapy for metastatic colorectal cancer-biweekly versus standard triweekly XELOX (The ORION Study).

scientific article

Multicentre phase II study of XELOX with bevacizumab in late-stage elderly patients with unresectable advanced/recurrent colorectal cancer: an ASCA study

scientific article published on 06 September 2010

One-Day Versus Three-Day Dexamethasone in Combination with Palonosetron for the Prevention of Chemotherapy-Induced Nausea and Vomiting: A Systematic Review and Individual Patient Data-Based Meta-Analysis

scientific article published on 19 June 2019

Open-label clinical trial of bezafibrate treatment in patients with fatty acid oxidation disorders in Japan.

scientific article

Open-label, randomized, comparative, phase III study on effects of reducing steroid use in combination with Palonosetron

scientific article published on 27 May 2015

Optimal Interval for 18F-FDG-PET After Chemoradiotherapy for Rectal Cancer

scientific article published on 21 November 2017

Optimal dose period for indisetron tablets for preventing chemotherapy-induced nausea and vomiting with modified FOLFOX6: a randomized pilot study

scientific article published on 01 January 2012

Optimal predictive value of preoperative serum carcinoembryonic antigen for surgical outcomes in stage I non‐small cell lung cancer: Differences according to histology and smoking status ⬇️

scientific article published on November 28, 2012

Pattern of programmed cell death-ligand 1 expression and CD8-positive T-cell infiltration before and after chemoradiotherapy in rectal cancer

scientific article published on 9 January 2018

Pharmacokinetic dose adjustment of 5-FU in modified FOLFOX7 plus bevacizumab for metastatic colorectal cancer in Japanese patients: a-JUST phase II clinical trial.

scientific article

Pharmacokinetic study of weekly administration dose of paclitaxel in patients with advanced or recurrent gastric cancer in Japan

scientific article published on 23 February 2007

Phase II study of weekly paclitaxel, cisplatin, and 5-fluorouracil for advanced gastric cancer

scientific article published on 06 April 2011

Phase II study on hepatic arterial infusion chemotherapy using percutaneous catheter placement techniques for liver metastases from colorectal cancer (JFMC28 study).

scientific article

Phase II trial of paclitaxel and cisplatin as neoadjuvant chemotherapy for locally advanced gastric cancer.

scientific article published on 5 March 2013

Prediction of the preoperative chemoradiotherapy response for rectal cancer by peripheral blood lymphocyte subsets

scientific article

Preservation of deep inferior epigastric artery at kidney transplantation prevents atrophy of lower rectus abdominis muscle

scientific article published on 01 May 2012

Prognosis of Japanese patients with previously untreated metastatic renal cell carcinoma in the era of molecular-targeted therapy

scientific article published on 19 March 2015

Prognostic Significance of Peritoneal Metastasis in Stage IV Colorectal Cancer Patients With R0 Resection: A Multicenter, Retrospective Study.

scientific article published in October 2017

Prognostic significance of epithelial-mesenchymal transition-related markers in extrahepatic cholangiocarcinoma: comprehensive immunohistochemical study using a tissue microarray

scientific article

Progression-free survival as a surrogate for overall survival in advanced/recurrent gastric cancer trials: a meta-analysis

scientific article published on 09 October 2013

Prospective phase II study of FOLFIRI for mCRC in Japan, including the analysis of UGT1A1 28/6 polymorphisms.

scientific article published on 7 February 2011

Randomized controlled Phase III study comparing hepatic arterial infusion with systemic chemotherapy after curative resection for liver metastasis of colorectal carcinoma: JFMC 29-0003.

scientific article published in January 2017

Randomized controlled trial on the skin toxicity of panitumumab in Japanese patients with metastatic colorectal cancer: HGCSG1001 study; J-STEPP.

scientific article

Randomized phase II study of cetuximab versus irinotecan and cetuximab in patients with chemo-refractory KRAS codon G13D metastatic colorectal cancer (G13D-study)

scientific article

Randomized phase III trial comparing surgery alone to UFT + PSK for stage II rectal cancer (JFMC38 trial).

scientific article published in November 2017

Rapid reduction in BCR-ABL1 transcript predicts deep molecular response in dasatinib-treated chronic-phase chronic myeloid leukaemia patients

scientific article published on 16 October 2017

Reduced-intensity vs myeloablative conditioning allogeneic hematopoietic SCT for patients aged over 45 years with ALL in remission: a study from the Adult ALL Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT)

scientific article published on 13 May 2013

Regional Differences in Prevalence of Macrolide Resistance among Pediatric Mycoplasma pneumoniae Infections in Hokkaido, Japan

scientific article published on 10 July 2015

Relationship between pre-anesthetic and intra-anesthetic airway resistance in patients undergoing general anesthesia: A prospective observational study

scientific article published on 17 February 2017

Relative increase in lymphocytes from as early as 1 month predicts improved response to dasatinib in chronic-phase chronic myelogenous leukemia.

scientific article

Remission induction by Raising the dose of Remicade in RA (RRRR) study: Rationale and study protocol for a randomized controlled trial comparing for sustained clinical remission after discontinuation of infliximab in patients with rheumatoid arthrit

scientific article

Role of chemotherapy for advanced/recurrent gastric cancer: an individual-patient-data meta-analysis

scientific article

Safety of laparoscopic surgery for colorectal cancer in patients over 80 years old: a propensity score matching study.

scientific article published on 27 January 2017

Sequential paclitaxel followed by tegafur and uracil (UFT) or S-1 versus UFT or S-1 monotherapy as adjuvant chemotherapy for T4a/b gastric cancer (SAMIT): a phase 3 factorial randomised controlled trial

scientific article published on 18 June 2014

Serum brain-derived neurotropic factor level predicts adverse clinical outcomes in patients with heart failure

scientific article published on 30 January 2015

Serum myostatin levels are independently associated with skeletal muscle wasting in patients with heart failure

scientific article published on 27 June 2016

Sleep-disordered breathing is an independent risk factor of aborted sudden cardiac arrest in patients with coronary artery spasm.

scientific article published on 2 June 2012

Statistical challenges for central monitoring in clinical trials: a review.

scientific article

Statistical evaluation of surrogate endpoints with examples from cancer clinical trials

scientific article

Temperament and character profiles of Japanese university students with depressive episodes and ideas of suicide or self-harm: a PHQ-9 screening study.

scientific article published on 10 July 2013

The COMET Open-label Phase II Study of Neoadjuvant FOLFOX or XELOX Treatment Combined with Molecular Targeting Monoclonal Antibodies in Patients with Resectable Liver Metastasis of Colorectal Cancer.

scientific article published on 8 September 2016

The domain structure of the EORTC QLQ-STO22 supported by Japanese validation data

scientific article

The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis

scientific article published on 24 April 2014

The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis

scientific article published on 16 June 2015

The influence of childhood abuse, adult stressful life events and temperaments on depressive symptoms in the nonclinical general adult population.

scientific article published on 10 February 2014

The potential diagnostic role of the number of ultrasonographic characteristics for patients with thyroid nodules evaluated as bethesda I-v.

scientific article

Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients.

scientific article

Transcatheter Arterial Embolization with Ethanol Injection in Symptomatic Patients with Enlarged Polycystic Kidneys.

scientific article published on 29 April 2015

Treatment using oxaliplatin and S-1 adjuvant chemotherapy for pathological stage III gastric cancer: a multicenter phase II study (TOSA trial) protocol

scientific article published on 13 February 2018

Two-by-two cross-over study to evaluate agreement between versions of a quantitative coronary analysis system (QAngio XA).

scientific article published on 21 January 2017

UGT1A1*6, 1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan.

scientific article published on 27 October 2013

Vasoactive-inotropic score as a predictor of morbidity and mortality in adults after cardiac surgery with cardiopulmonary bypass

scientific article published on 13 January 2018

mFOLFOX6 Plus Panitumumab Versus 5-FU/LV Plus Panitumumab After Six Cycles of Frontline mFOLFOX6 Plus Panitumumab: A Randomized Phase II Study of Patients With Unresectable or Advanced/Recurrent, RAS Wild-type Colorectal Carcinoma (SAPPHIRE)-Study D

scientific article published on March 2017

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