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List of works by Michael Boettcher

A mammosphere formation RNAi screen reveals that ATG4A promotes a breast cancer stem-like phenotype.

scientific article

An in vivo RNAi screen identifies SALL1 as a tumor suppressor in human breast cancer with a role in CDH1 regulation.

scientific article published on 2 December 2013

Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches

scientific article published on 02 March 2020

Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR.

scientific article

Decoding pooled RNAi screens by means of barcode tiling arrays

scientific article

Depletion of RAD17 sensitizes pancreatic cancer cells to gemcitabine.

scientific article published on 17 May 2013

Dissection of CD20 regulation in lymphoma using RNAi

scientific article published on 18 August 2016

Dual gene activation and knockout screen reveals directional dependencies in genetic networks

scientific article published on 15 January 2018

ER-alpha-cDNA as part of a bicistronic transcript gives rise to high frequency, long term, receptor expressing cell clones

scientific article

Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model system

scientific article

Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation.

scientific article published on 9 April 2018

High throughput synthetic lethality screen reveals a tumorigenic role of adenylate cyclase in fumarate hydratase-deficient cancer cells

scientific article

Host-Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity

scientific article published on 06 February 2020

Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin.

scientific article

Identification of X-chromosomal genes that drive sex differences in embryonic stem cells through a hierarchical CRISPR screening approach

scientific article published on 16 April 2021

Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells

scientific article published on 10 June 2022

Pooled RNAi Screens - Technical and Biological Aspects.

scientific article

Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding

scientific article published on 06 February 2019

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