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List of works by David MacMillan

A General Small-Scale Reactor To Enable Standardization and Acceleration of Photocatalytic Reactions

scientific article published on 17 May 2017

A Mechanistic Analysis of Metallaphotoredox C-N Coupling: Photocatalysis Initiates and Perpetuates Ni(I)/Ni(III) Coupling Activity

scientific article published on 04 August 2020

A Metallaphotoredox Strategy for the Cross-Electrophile Coupling of α-Chloro Carbonyls with Aryl Halides

scientific article published on 05 September 2019

A general and enantioselective approach to pentoses: a rapid synthesis of PSI-6130, the nucleoside core of sofosbuvir

scientific article published on 9 April 2014

A general method for the enantioselective synthesis of pantolactone derivatives

scientific article published on 01 October 2002

A general strategy for organocatalytic activation of C-H bonds via photoredox catalysis: direct arylation of benzylic ethers

scientific article published on 27 December 2013

A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes

scientific article published on 01 June 2018

Alcohols as Latent Coupling Fragments for Metallaphotoredox Catalysis: sp3-sp2 Cross-Coupling of Oxalates with Aryl Halides

scientific article published on 9 October 2016

Alcohols as alkylating agents in heteroarene C-H functionalization

scientific article published on 26 August 2015

Aryl amination using ligand-free Ni(II) salts and photoredox catalysis

scientific article published on 23 June 2016

Carboxylic acids as a traceless activation group for conjugate additions: a three-step synthesis of (±)-pregabalin.

scientific article published on 28 July 2014

Catalyst-controlled oligomerization for the collective synthesis of polypyrroloindoline natural products

scientific article published on 24 July 2017

Collective synthesis of natural products by means of organocascade catalysis ⬇️

scientific article published on July 13, 2011

Concerning the mechanism of the FeCl3-catalyzed alpha-oxyamination of aldehydes: evidence for a non-SOMO activation pathway

scientific article published on July 2010

Copper-Catalyzed Trifluoromethylation of Alkyl Bromides

scientific article published on 18 April 2019

Copper-mediated synthesis of drug-like bicyclopentanes

scientific article published on 17 February 2020

Correction to "Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling".

scientific article published on 28 January 2016

Cross-Electrophile Coupling of Unactivated Alkyl Chlorides

scientific article published on 20 June 2020

Cycle-specific organocascade catalysis: application to olefin hydroamination, hydro-oxidation, and amino-oxidation, and to natural product synthesis

scientific article published on January 2009

Decarboxylative Hydroalkylation of Alkynes

scientific article published on 17 April 2018

Decarboxylative Peptide Macrocyclization through Photoredox Catalysis.

scientific article published on 17 November 2016

Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids

scientific article published on 21 May 2018

Decarboxylative alkylation for site-selective bioconjugation of native proteins via oxidation potentials.

scientific article

Decarboxylative arylation of α-amino acids via photoredox catalysis: a one-step conversion of biomass to drug pharmacophore

scientific article published on 31 March 2014

Decarboxylative sp C-N coupling via dual copper and photoredox catalysis

scientific article published in Nature

Decarboxylative sp3 C–N Coupling via Dual Copper/Photoredox Catalysis

Decarboxylative sp3 C–N Coupling via Dual Copper/Photoredox Catalysis

Development of a general, enantioselective organocatalytic Mukaiyama-Michael reaction with α,β-unsaturated aldehydes

scientific article published on August 2009

Development of a new Lewis acid-catalyzed [3,3]-sigmatropic rearrangement: the allenoate-Claisen rearrangement

scientific article published in November 2002

Direct Aldehyde C-H Arylation and Alkylation via the Combination of Nickel, Hydrogen Atom Transfer, and Photoredox Catalysis.

scientific article published on 6 August 2017

Direct and enantioselective organocatalytic alpha-chlorination of aldehydes

scientific article

Direct and enantioselective α-allylation of ketones via singly occupied molecular orbital (SOMO) catalysis ⬇️

scientific article published on October 4, 2010

Direct arylation of strong aliphatic C-H bonds

scientific article published in Nature

Direct α-arylation of ethers through the combination of photoredox-mediated C-H functionalization and the Minisci reaction.

scientific article published on 2 December 2014

Direct β-alkylation of aldehydes via photoredox organocatalysis

scientific article published on 29 April 2014

Direct β-functionalization of cyclic ketones with aryl ketones via the merger of photoredox and organocatalysis

scientific article

Direct, enantioselective α-alkylation of aldehydes using simple olefins

scientific article published on 26 June 2017

Discovery of an α-Amino C–H Arylation Reaction Using the Strategy of Accelerated Serendipity ⬇️

scientific article published on November 25, 2011

Dual catalysis. Merging photoredox with nickel catalysis: coupling of α-carboxyl sp³-carbons with aryl halides

scientific article

Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function?

scientific article published on 19 April 2011

Enantioselective Decarboxylative Arylation of α-Amino Acids via the Merger of Photoredox and Nickel Catalysis.

scientific article

Enantioselective Organo-SOMO Cycloadditions: A Catalytic Approach to Complex Pyrrolidines from Olefins and Aldehydes ⬇️

scientific article published on July 10, 2012

Enantioselective Total Synthesis of (-)-7-Deacetoxyalcyonin Acetate. First Synthesis of a Eunicellin Diterpene

scientific article published in 1995

Enantioselective aldehyde alpha-nitroalkylation via oxidative organocatalysis.

scientific article

Enantioselective alpha-arylation of aldehydes via organo-SOMO catalysis. An ortho-selective arylation reaction based on an open-shell pathway

scientific article published on August 2009

Enantioselective alpha-trifluoromethylation of aldehydes via photoredox organocatalysis

scientific article

Enantioselective copper-catalyzed construction of aryl pyrroloindolines via an arylation-cyclization cascade ⬇️

scientific article published on June 22, 2012

Enantioselective intramolecular aldehyde α-alkylation with simple olefins: direct access to homo-ene products

scientific article published on 12 June 2013

Enantioselective linchpin catalysis by SOMO catalysis: an approach to the asymmetric alpha-chlorination of aldehydes and terminal epoxide formation.

scientific article published on January 2009

Enantioselective organo-SOMO cascade cycloadditions: a rapid approach to molecular complexity from simple aldehydes and olefins

scientific article published on July 2010

Enantioselective organo-SOMO catalysis: the alpha-vinylation of aldehydes

scientific article published on 21 December 2007

Enantioselective organo-cascade catalysis

scientific article

Enantioselective organo-singly occupied molecular orbital catalysis: the carbo-oxidation of styrenes

scientific article published on December 2008

Enantioselective organocatalytic amine conjugate addition

scientific article published in July 2006

Enantioselective organocatalytic construction of pyrroloindolines by a cascade addition-cyclization strategy: synthesis of (-)-flustramine B.

scholarly article

Enantioselective organocatalytic cyclopropanations. The identification of a new class of iminium catalyst based upon directed electrostatic activation.

scientific article

Enantioselective organocatalytic direct aldol reactions of alpha-oxyaldehydes: step one in a two-step synthesis of carbohydrates

scientific article

Enantioselective organocatalytic hydride reduction

scientific article

Enantioselective organocatalytic indole alkylations. Design of a new and highly effective chiral amine for iminium catalysis

scientific article published in February 2002

Enantioselective organocatalytic reductive amination

scientific article

Enantioselective organocatalytic singly occupied molecular orbital activation: the enantioselective alpha-enolation of aldehydes

scientific article

Enantioselective organocatalytic transfer hydrogenation reactions using Hantzsch esters

scientific article published on December 2007

Enantioselective organocatalytic α-fluorination of cyclic ketones

scientific article

Enantioselective α-Alkylation of Aldehydes by Photoredox Organocatalysis: Rapid Access to Pharmacophore Fragments from β-Cyanoaldehydes

scientific article published on 30 June 2015

Enantioselective α-Arylation of Aldehydes via the Productive Merger of Iodonium Salts and Organocatalysis ⬇️

scientific article published on March 9, 2011

Enantioselective α-Arylation of Carbonyls via Cu(I)-Bisoxazoline Catalysis ⬇️

scientific article published on August 17, 2011

Enantioselective α-Benzylation of Aldehydes via Photoredox Organocatalysis ⬇️

scientific article published on October 6, 2010

Enantioselective α-vinylation of aldehydes via the synergistic combination of copper and amine catalysis

scientific article

Fragment Couplings via CO2 Extrusion-Recombination: Expansion of a Classic Bond-Forming Strategy via Metallaphotoredox

scientific article published on 2 September 2015

Mechanistic complexity in organo-SOMO activation

scientific article

Merging Photoredox and Nickel Catalysis: The Direct Synthesis of Ketones by the Decarboxylative Arylation of α-Oxo Acids

scientific article published on 26 May 2015

Merging photoredox and nickel catalysis: decarboxylative cross-coupling of carboxylic acids with vinyl halides.

scientific article published on 12 January 2015

Merging photoredox catalysis with organocatalysis: the direct asymmetric alkylation of aldehydes

scientific article

Metallaphotoredox Difluoromethylation of Aryl Bromides

scientific article published on 28 August 2018

Metallaphotoredox Perfluoroalkylation of Organobromides

scientific article published on 09 November 2020

Metallaphotoredox aryl and alkyl radiomethylation for PET ligand discovery

scientific article published on 25 November 2020

Metallaphotoredox-Catalyzed Cross-Electrophile Csp3-Csp3 Coupling of Aliphatic Bromides

scientific article published on 10 December 2018

Metallaphotoredox-catalysed sp(3)-sp(3) cross-coupling of carboxylic acids with alkyl halides.

scientific article

Microenvironment mapping via Dexter energy transfer on immune cells

scientific article published on 01 March 2020

Native functionality in triple catalytic cross-coupling: sp³ C-H bonds as latent nucleophiles

scientific article published on 28 April 2016

Nature of intermediates in organo-SOMO catalysis of alpha-arylation of aldehydes

scientific article

New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction

article

Nine-step enantioselective total synthesis of (+)-minfiensine

scientific article published on September 2009

Nine-step enantioselective total synthesis of (-)-vincorine

scientific article published on 19 April 2013

O-H hydrogen bonding promotes H-atom transfer from α C-H bonds for C-alkylation of alcohols

scientific article published on 27 August 2015

Open-Shell Fluorination of Alkyl Bromides: Unexpected Selectivity in a Silyl Radical-Mediated Chain Process

scientific article published on 12 December 2019

Organocatalysis ⬇️

scientific article published on November 30, 2010

Organocatalytic transfer hydrogenation of cyclic enones

scientific article

Organocatalytic vinyl and Friedel-Crafts alkylations with trifluoroborate salts

scientific article

Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling

scientific article published on 31 August 2015

Oxy-Allyl Cation Catalysis: An Enantioselective Electrophilic Activation Mode

scientific article published on 21 January 2016

Photoredox Catalysis in Organic Chemistry

scientific article

Photoredox activation for the direct β-arylation of ketones and aldehydes

scientific article

Photoredox catalysis: a mild, operationally simple approach to the synthesis of α-trifluoromethyl carbonyl compounds.

scientific article published on 23 May 2011

Photoredox α-vinylation of α-amino acids and N-aryl amines

scientific article

Photoredox-catalyzed deoxyfluorination of activated alcohols with Selectfluor®

scientific article published on 03 June 2019

Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds

scientific article

Photosensitized, energy transfer-mediated organometallic catalysis through electronically excited nickel(II).

scientific article published in January 2017

Selective Hydrogen Atom Abstraction through Induced Bond Polarization: Direct α-Arylation of Alcohols through Photoredox, HAT, and Nickel Catalysis.

scientific article published on 28 February 2018

Selective Radical-Radical Cross-Couplings: Design of a Formal β-Mannich Reaction

scientific article published on 29 June 2015

Selective sp3 C-H alkylation via polarity-match-based cross-coupling

scientific article published on 21 June 2017

Silyl Radical Activation of Alkyl Halides in Metallaphotoredox Catalysis: A Unique Pathway for Cross-Electrophile Coupling

scientific article

Simple catalytic mechanism for the direct coupling of α-carbonyls with functionalized amines: a one-step synthesis of Plavix.

scientific article published on 16 October 2013

Site-Selective Functionalization of Methionine Residues via Photoredox Catalysis

scientific article published on 08 December 2020

Site-selective tyrosine bioconjugation via photoredox catalysis for native-to-bioorthogonal protein transformation

scientific article published in 2021

Spin-Center Shift-Enabled Direct Enantioselective a-Benzylation of Aldehydes with Alcohols.

scientific article

Static to inducibly dynamic stereocontrol: The convergent use of racemic β-substituted ketones

scientific article

Sulfonamidation of Aryl and Heteroaryl Halides via Photosensitized Nickel Catalysis

scientific article published on 9 February 2018

Switching on elusive organometallic mechanisms with photoredox catalysis

scientific article published on 12 August 2015

The advent and development of organocatalysis

scientific article (publication date: 18 September 2008)

The direct and enantioselective organocatalytic alpha-oxidation of aldehydes

scientific article

The direct arylation of allylic sp(3) C-H bonds via organic and photoredox catalysis

scientific article published on March 2015

The enantioselective organocatalytic 1,4-addition of electron-rich benzenes to alpha,beta-unsaturated aldehydes

scientific article published in July 2002

The first Suzuki cross-couplings of aryltrimethylammonium salts

scientific article published in May 2003

The first direct and enantioselective cross-aldol reaction of aldehydes

scientific article

The first enantioselective organocatalytic Mukaiyama-Michael reaction: a direct method for the synthesis of enantioenriched gamma-butenolide architecture

scientific article

The first general enantioselective catalytic Diels-Alder reaction with simple alpha,beta-unsaturated ketones

scientific article

The importance of iminium geometry control in enamine catalysis: identification of a new catalyst architecture for aldehyde-aldehyde couplings

scientific article published in December 2004

The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)-H trifluoromethylation

scientific article published on 16 March 2020

Total synthesis and structural revision of callipeltoside C.

scientific article published on January 2008

Total synthesis of brasoside and littoralisone

scientific article published in March 2005

Transient Absorption Spectroscopy Offers Mechanistic Insights for an Iridium/Nickel-Catalyzed C-O Coupling

scientific article published on 25 February 2020

Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis.

scientific article

Two-step synthesis of carbohydrates by selective aldol reactions

scientific article

Visible light photoredox catalysis with transition metal complexes: applications in organic synthesis

scientific article

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