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List of works by David L. Spector

"On the move"ments of nuclear components in living cells

scientific article published on May 2004

3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA

scientific article

3D segmentation and quantification of mouse embryonic stem cells in fluorescence microscopy images

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

scientific article published on 19 October 2008

A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence

scientific article

A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation

scientific article published on 18 August 2017

A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression

scientific article published on 15 September 2010

A molecular dissection of nuclear function. Conference on the dynamic nucleus: questions and implications

scientific article published in January 2003

An unexpected ending: noncanonical 3' end processing mechanisms.

scientific article published on 09 December 2009

Antisense Oligonucleotide-mediated Knockdown in Mammary Tumor Organoids

scientific article published on August 2017

BiFC imaging assay for plant protein-protein interactions

scientific article published on 01 February 2010

Biogenesis and function of nuclear bodies ⬇️

scientific article published on June 15, 2011

Centromere positioning and dynamics in living Arabidopsis plants

scientific article

Chromatin dynamics

scientific article

Chromatin dynamics and gene positioning

scientific article published on March 2008

Chromatin meets its organizers

scientific article published in June 2013

Chromatin organization and transcriptional regulation

scientific article published on 24 December 2012

Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing

scientific article published on 04 September 2020

Constructing and Expressing Fluorescent Protein Fusions ⬇️

scientific article published on 01 November 2010

Constructing and Expressing GFP Fusion Proteins ⬇️

scientific article published on 01 December 2006

Differential regulation of strand-specific transcripts from Arabidopsis centromeric satellite repeats

scientific article

Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes

scientific article published on 10 December 2001

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss

scientific article

Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs ⬇️

scientific article published on December 19, 2010

Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing

scientific article published on 4 February 2002

Dynamics of single mRNPs in nuclei of living cells.

scientific article

Eukaryotic regulatory RNAs: an answer to the 'genome complexity' conundrum

scientific article

Four amino acids guide the assembly or disassembly of Arabidopsis histone H3.3-containing nucleosomes ⬇️

scientific article published on June 13, 2011

Four-dimensional imaging of plant cells during the cell cycle.

scientific article published in February 2010

From silencing to gene expression: real-time analysis in single cells

scientific article

Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation ⬇️

scientific article published on October 9, 2011

Genome-wide transposon tagging reveals location-dependent effects on transcription and chromatin organization in Arabidopsis

scientific article

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance

scientific article

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance

Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei

scientific article

Identification and Characterization of a Class of MALAT1-like Genomic Loci

scientific article

Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA.

scientific article

Identification of nuclear dicing bodies containing proteins for microRNA biogenesis in living Arabidopsis plants

scientific article

Immunofluorescence Localization of Nuclear Proteins: Figure 1 ⬇️

scientific article published on 01 October 2011

Lamin A/C is expressed in pluripotent mouse embryonic stem cells

scientific article published on January 2013

Live cell dynamics of promyelocytic leukemia nuclear bodies upon entry into and exit from mitosis

scientific article

Live cell imaging of plants

scientific article published on 01 February 2010

Long non-coding RNAs: modulators of nuclear structure and function

scientific article published on 20 September 2013

MALAT1 Long Non-Coding RNA: Functional Implications

scientific article published on 03 June 2020

MALAT1 long non-coding RNA and breast cancer

scientific article published on 22 March 2019

MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles

scientific article

MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression

scientific article published on 22 December 2020

Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration

scientific article published on September 2016

Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus

scientific article

Multiple structural maintenance of chromosome complexes at transcriptional regulatory elements.

scientific article published on 24 October 2013

Non-rigid multi-frame registration of cell nuclei in live cell fluorescence microscopy image data

scientific article

Nonrigid registration of 2-D and 3-D dynamic cell nuclei images for improved classification of subcellular particle motion

scientific article published on 13 September 2010

Nuclear Organization and Dynamics of 7SK RNA in Regulating Gene Expression ⬇️

scientific article published on September 29, 2010

Nuclear choreography: interpretations from living cells

scientific article

Nuclear neighborhoods and gene expression

scientific article

Nuclear speckles

scientific article

Nuclear speckles: a model for nuclear organelles

scientific article

Nucleus and gene expression

PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein

scientific article

POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer.

scientific article published on 26 June 2018

Proteomic analysis of interchromatin granule clusters

scientific article

Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2

scientific article published on 21 November 2015

Random monoallelic expression: regulating gene expression one allele at a time

scientific article

Random monoallelic gene expression increases upon embryonic stem cell differentiation

scientific article

Rapid, diffusional shuttling of poly(A) RNA between nuclear speckles and the nucleoplasm

scientific article

Receptor-mediated delivery of engineered nucleases for genome modification

scientific article published on 16 August 2013

Regulating gene expression through RNA nuclear retention

scientific article

Regulation of the ESC transcriptome by nuclear long noncoding RNAs

scientific article

Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage

scientific article

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

scientific article

Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1

scientific article published on 31 January 2019

Sequential entry of components of the gene expression machinery into daughter nuclei

scientific article

SnapShot: Cellular bodies

scientific article published on 01 December 2006

Spatial and temporal regulation of Condensins I and II in mitotic chromosome assembly in human cells.

scientific article published on 14 May 2004

Stopping for FISH and chips along the chromatin fiber superhighway

scientific article published on 01 September 2004

Testing for phylogenetic signal in single-cell RNA-seq data

The Dynamics of Chromosome Organization and Gene Regulation ⬇️

scientific article published on January 1, 2003

The life of an mRNA in space and time

scientific article

The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult ⬇️

scientific article published on June 28, 2012

The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells

scientific article

Therapeutic Targeting of Long Non-Coding RNAs in Cancer

scientific article published on 12 February 2018

Tissue-specific expression and dynamic organization of SR splicing factors in Arabidopsis

scientific article

Transfection of Mammalian Cells with Fluorescent Protein Fusions ⬇️

scientific article published on November 1, 2010

Transient pairing of homologous Oct4 alleles accompanies the onset of embryonic stem cell differentiation

scientific article published on March 2015

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