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List of works by David Kerr

'Toxgnostics': an unmet need in cancer medicine

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS

scientific article

A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

scientific article published on 20 May 2015

Addressing unwarranted variations in colorectal cancer outcomes: a conceptual approach.

scientific article

Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial

scientific article published on 19 September 2016

Adjuvant chemotherapy for stage II colon cancer: less complicated than we thought

scientific article published on 18 March 2013

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

scientific article

Analyses of 7,635 Patients with Colorectal Cancer Using Independent Training and Validation Cohorts Show That rs9929218 in CDH1 Is a Prognostic Marker of Survival ⬇️

scientific article published on 14 April 2015

Biological markers: Tailoring treatment and trials to prognosis

scientific article published on 11 June 2013

Biomarkers in early-stage colorectal cancer: ready for prime time?

scientific article

Building capacity for sustainable research programmes for cancer in Africa

scientific article

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

scientific article

Determinants of Early Mortality Among 37,568 Patients With Colon Cancer Who Participated in 25 Clinical Trials From the Adjuvant Colon Cancer Endpoints Database

scientific article published on 8 February 2016

Erratum: A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

scientific article published on 3 August 2015

Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer

scientific article

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis

scientific article

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

scientific article published on 28 September 2017

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas ⬇️

scientific article

HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials ⬇️

scientific article published on 22 December 2015

Health diplomacy: a new approach to the Muslim world?

scientific article

Intra-tumoural stromal morphometry predicts disease recurrence but not response to 5-fluorouracil - results from the QUASAR trial of colorectal cancer. ⬇️

scientific article

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN.

scientific article

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

scientific article published on 23 June 2016

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

scientific article

Methylation changes in the TFAP2E promoter region are associated with BRAF mutation and poorer overall & disease free survival in colorectal cancer.

scientific article published on 23 March 2015

Policy: EU data protection regulation--harming cancer research

scientific article

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

scientific article

Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer

scientific article published on 09 August 2012

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

scientific article published on 20 July 2016

Stage II colon cancer.

scientific article published on June 2013

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

scientific article published on 17 September 2013

The Oncology Data Network (ODN): A Collaborative European Data-Sharing Platform to Inform Cancer Care

scientific article published on 05 September 2019

The TERT variant rs2736100 is associated with colorectal cancer risk

scientific article

The predictive and prognostic value of sex in early-stage colon cancer: a pooled analysis of 33,345 patients from the ACCENT database

scientific article published on 27 June 2013

The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial

scientific article published on 02 August 2012

Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.

scientific article published on February 2013

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

scientific article published on 22 March 2016

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