Search filters

List of works by David J. Brockwell

A force-activated trip switch triggers rapid dissociation of a colicin from its immunity protein

scientific article

A peptide-display protein scaffold to facilitate single molecule force studies of aggregation-prone peptides ⬇️

scientific article published on 8 February 2018

A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function

scientific article published on 09 March 2020

An in vivo platform for identifying inhibitors of protein aggregation ⬇️

scientific article published on 14 December 2015

An in vivo platform to select and evolve aggregation-resistant proteins

scientific article published on 14 April 2020

Assessing the Potential of Folded Globular Polyproteins As Hydrogel Building Blocks ⬇️

scientific article published on 22 December 2016

Cooperative folding of intrinsically disordered domains drives assembly of a strong elongated protein ⬇️

scientific article

Correction

Differential Effects of Hydrophobic Core Packing Residues for Thermodynamic and Mechanical Stability of a Hyperthermophilic Protein ⬇️

scientific article published on 23 June 2016

Dissecting the effects of periplasmic chaperones on the in vitro folding of the outer membrane protein PagP ⬇️

scientific article

Distortion of the bilayer and dynamics of the BAM complex in lipid nanodiscs

scientific article published on 14 December 2020

Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding

scientific article published on 08 June 2022

Dynamics of the coiled-coil unfolding transition of myosin rod probed by dissipation force spectrum

scientific article published in July 2010

Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding ⬇️

scientific article published on 15 September 2017

Erratum: Pulling geometry defines the mechanical resistance of a β-sheet protein

scientific article published in October 2003

Extraction of accurate biomolecular parameters from single-molecule force spectroscopy experiments ⬇️

scientific article published on 5 February 2015

Force-induced remodelling of proteins and their complexes ⬇️

scientific article

Gating of TonB-dependent transporters by substrate-specific forced remodelling ⬇️

scientific article published on 21 April 2017

Identification of a mechanical rheostat in the hydrophobic core of protein L.

scientific article

Improved methods of cultivation and production of deuteriated proteins from E. coli strains grown on fully deuteriated minimal medium

scientific article published in April 2003

Inducing protein aggregation by extensional flow ⬇️

scientific article published on 17 April 2017

Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients

scientific article published on 01 May 2020

Intermediates: ubiquitous species on folding energy landscapes?

scientific article published on 18 January 2007

Internal friction of single polypeptide chains at high stretch

scientific article

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM. ⬇️

scientific article

Life in extreme environments: single molecule force spectroscopy as a tool to explore proteins from extremophilic organisms ⬇️

scientific article published on April 2015

Malleability of the folding mechanism of the outer membrane protein PagP: parallel pathways and the effect of membrane elasticity

scientific article published on 8 January 2012

Mechanical resistance of proteins explained using simple molecular models

scientific article

Mechanically unfolding protein L using a laser-feedback-controlled cantilever

scientific article published in April 2011

Mechanically unfolding proteins: the effect of unfolding history and the supramolecular scaffold

scientific article

Mechanically unfolding the small, topologically simple protein L.

scientific article published on 29 April 2005

Mechanistic studies of the biogenesis and folding of outer membrane proteins in vitro and in vivo: what have we learned to date? ⬇️

scientific article published on 05 March 2014

Optimizing the calculation of energy landscape parameters from single-molecule protein unfolding experiments ⬇️

scientific article published on 26 January 2015

Outer membrane protein folding from an energy landscape perspective ⬇️

scientific article published on 21 December 2017

Phosphorylation-induced unfolding regulates p19INK4d during the human cell cycle ⬇️

scientific article published on 12 March 2018

Physicochemical consequences of the perdeuteriation of glutathione S-transferase from S. japonicum

scientific article published in March 2001

Prediction of the translocation kinetics of a protein from its mechanical properties

scientific article published on 30 June 2006

Prying open single GroES ring complexes by force reveals cooperativity across domains

scientific article published in April 2012

Pulling geometry defines the mechanical resistance of a beta-sheet protein

scientific article

PyXlinkViewer: a flexible tool for visualisation of protein chemical crosslinking data within the PyMOL molecular graphics system

scientific article published on 18 June 2020

Rapid Mapping of Protein Interactions Using Tag-Transfer Photocrosslinkers ⬇️

scientific article published on 21 November 2018

Rapid Mapping of Protein Interactions Using Tag‐Transfer Photocrosslinkers

Rapid and Robust Polyprotein Production Facilitates Single-Molecule Mechanical Characterization of β-Barrel Assembly Machinery Polypeptide Transport Associated Domains ⬇️

scientific article

Single molecule protein stabilisation translates to macromolecular mechanics of a protein network

scientific article published on 24 June 2020

Single-molecule force spectroscopy identifies a small cold shock protein as being mechanically robust

scientific article

Single-molecule studies of the Im7 folding landscape

scientific article published on 6 March 2010

Skp is a multivalent chaperone of outer-membrane proteins ⬇️

scientific article published on 25 July 2016

Structural investigations of kirromycin bound to bacterial elongation factor Tu by NMR and molecular dynamics.

scientific article

The N-terminal helix is a post-assembly clamp in the bacterial outer membrane protein PagP.

scientific article

The X-ray crystal structures of perdeuteriated and protiated enzyme elongation factor Tu are very similar

scientific article published in 1998

The effect of core destabilization on the mechanical resistance of I27.

scientific article

The effect of protein complexation on the mechanical stability of Im9.

scientific article published on 9 March 2007

The effect of temperature on mechanical resistance of the native and intermediate states of I27.

scientific article published on 5 September 2008

The transition state for folding of an outer membrane protein

scientific article

Towards design principles for determining the mechanical stability of proteins ⬇️

scientific article

Tuning protein mechanics through an ionic cluster graft from an extremophilic protein ⬇️

scientific article published on 26 January 2016

Tuning the elastic modulus of hydrated collagen fibrils

scientific article published on December 2009

Unfolding dynamics of proteins under applied force ⬇️

scientific article

Unravelling the design principles for single protein mechanical strength

scientific article published on 09 June 2010

Urea-induced unfolding of the immunity protein Im9 monitored by spFRET.

scientific article published on 23 June 2006

Using extensional flow to reveal diverse aggregation landscapes for three IgG1 molecules ⬇️

scientific article published on 8 January 2018

Using protein engineering to understand and modulate aggregation

scientific article published on 19 February 2020

Viscoelastic study of the mechanical unfolding of a protein by AFM.

scientific article published on 12 May 2006

Paulina is supported by:

About Paulina

Help