Search filters

List of works by Timothy Hill

A Novel Long-Range n to π* Interaction Secures the Smallest known α-Helix in Water

scientific article published on 08 November 2019

Comparative α-helicity of cyclic pentapeptides in water

scientific article

Constraining cyclic peptides to mimic protein structure motifs.

scientific article

Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed

scientific article

De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex

scientific article published on 01 December 2021

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

scientific article

Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides

scientific article published on 07 October 2015

Green chemistry approaches to the Knoevenagel condensation: comparison of ethanol, water and solvent free (dry grind) approaches

Helix Nucleation by the Smallest Known α-Helix in Water.

scientific article

Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception.

scientific article

Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling.

scientific article published on 21 October 2016

Heterocyclic substituted cantharidin and norcantharidin analogues—synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity

scientific article published on 02 April 2007

Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis

scientific article

Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable

scientific article published on 12 September 2014

Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles

scientific article

Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity

scientific article

Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities

scientific article published on 21 October 2019

Norcantharidin analogues: synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition

scientific article

Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation

scientific article published on 20 June 2007

Novel Helix-Constrained Nociceptin Derivatives Are Potent Agonists and Antagonists of ERK Phosphorylation and Thermal Analgesia in Mice

scientific article published on November 10, 2010

Parallel Solution-Phase Synthesis of Targeted Tyrphostin Libraries with Anticancer Activity

Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.

scientific article

Small molecule inhibitors of dynamin I GTPase activity: development of dimeric tyrphostins

scientific article published in December 2005

Synthesis and biological evaluation of norcantharidin analogues: Towards PP1 selectivity

scientific article published on 24 August 2007

The antiplasmodial activity of norcantharidin analogs.

scientific article published on 7 September 2010

Truncated and helix-constrained peptides with high affinity and specificity for the cFos coiled-coil of AP-1

scientific article

Twists or turns: stabilising alpha vs. beta turns in tetrapeptides

scientific article published on 03 October 2019

Update 1 of: Beta-strand mimetics.

scientific article published on 12 April 2010