List of works - Janet Newman

300-Fold Increase in Production of the Zn2+-Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme Stabilization

scientific article

A Nondenaturing Purification Scheme for the DNA-Binding Domain of Poly(ADP-Ribose) Polymerase, a Structure-Specific DNA-Binding Protein ⬇️

scientific article published on October 1, 1998

A drunken search in crystallization space

scientific article

A new crystal form of human vascular adhesion protein 1

scientific article

A novel decarboxylating amidohydrolase involved in avoiding metabolic dead ends during cyanuric acid catabolism in Pseudomonas sp. strain ADP

scientific article published in PLoS ONE

A universal indicator dye pH assay for crystallization solutions and other high-throughput applications

scientific article published on 17 July 2012

An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme.

scientific article published on 9 March 2018

BLASTing away preconceptions in crystallization trials

scientific article published on 21 February 2019

Cinder: keeping crystallographers app-y

scientific article published on 26 June 2018

Classification of crystallization outcomes using deep convolutional neural networks.

scientific article

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera

scientific article published on 25 November 2011

Contamination or serendipity - doing the wrong thing by chance

scientific article published on 01 September 2020

Crystal Structure of an Indole-3-Acetic Acid Amido Synthetase from Grapevine Involved in Auxin Homeostasis ⬇️

scientific article published on November 6, 2012

Crystal structure of a putrescine aminotransferase from Pseudomonas sp. strain AAC.

scientific article published on January 2017

Crystal structures of human ENPP1 in apo and bound forms

scientific article published on 17 August 2020

Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site

scientific article

Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.

scientific article published on 30 April 2010

Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate

scientific article published on 14 February 2009

Crystallization and preliminary X-ray analysis of the complexes between a Fab and two forms of human insulin-like growth factor II.

scientific article published on 26 August 2009

Crystallization and preliminary X-ray diffraction analysis of the amidase domain of allophanate hydrolase from Pseudomonas sp. strain ADP.

scientific article published on 19 February 2014

Crystallization of an apo form of human arginase: using all the tools in the toolbox simultaneously

scientific article published on 23 December 2010

Crystallization reports are the backbone of Acta Cryst. F, but do they have any spine?

scientific article published on 30 June 2013

Crystallization screening: the influence of history on current practice.

scientific article

Crystallization: digging into the past to learn lessons for the future.

scientific article published on January 2015

Cyanuric acid hydrolase: evolutionary innovation by structural concatenation

scientific article published in June 2013

Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices

scientific article published in 2021

Determination of the Structure of the Catabolic N-Succinylornithine Transaminase (AstC) from Escherichia coli

scientific article

Evaluating Protic Ionic Liquids as Protein Crystallization Additives

Expanding screening space through the use of alternative reservoirs in vapor-diffusion experiments

scientific article published on 24 March 2005

Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK

scientific article

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography

scientific article published on 29 April 2019

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography

scientific article published on 30 April 2019

Formulation screening by differential scanning fluorimetry: how often does it work?

scientific article published on 23 September 2015

Fragment screening for a protein-protein interaction inhibitor to WDR5

scientific article published on 14 November 2019

From information management to protein annotation: preparing protein structures for drug discovery.

scientific article

Germline humanization of a murine Aβ antibody and crystal structure of the humanized recombinant Fab fragment

scientific article

Haloalkane dehalogenases: structure of a Rhodococcus enzyme

scientific article

High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.

scientific article published on 24 February 2017

High-Throughput Production and Structural Characterization of Libraries of Self-Assembly Lipidic Cubic Phase Materials ⬇️

scientific article published on March 23, 2012

High-throughput thermal scanning for protein stability: making a good technique more robust.

scientific article published on 10 June 2013

Identification and characterization of two families of F420H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation

scientific article

Identifying, studying and making good use of macromolecular crystals.

scientific article

Improved success of sparse matrix protein crystallization screening with heterogeneous nucleating agents

scientific article

Initial evaluations of the reproducibility of vapor-diffusion crystallization

scientific article published on 15 June 2007

Innovation versus practice in biological crystallization

scientific article published on 02 July 2020

Interrogating HIV integrase for compounds that bind- a SAMPL challenge

scientific article

Introducing Methods Communications, a new category of contributions to Acta Crystallographica F

scientific article published on 06 August 2019

Lipidic Cubic Phase-Induced Membrane Protein Crystallization: Interplay Between Lipid Molecular Structure, Mesophase Structure and Properties, and Crystallogenesis

Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2

scientific article published on 26 August 2020

Meltdown: A Tool to Help in the Interpretation of Thermal Melt Curves Acquired by Differential Scanning Fluorimetry

scientific article published on 27 April 2015

Nitrate in the active site of protein tyrosine phosphatase 1B is a putative mimetic of the transition state

scientific article

Novel buffer systems for macromolecular crystallization

scientific article published on 25 February 2004

On the need for an international effort to capture, share and use crystallization screening data

scientific article (publication date: March 2012)

One plate, two plates, a thousand plates. How crystallisation changes with large numbers of samples.

scientific article published on 6 May 2011

Parallel and antiparallel cyclic d/l peptide nanotubes.

scientific article

Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?

scientific article

Phoenito experiments: combining the strengths of commercial crystallization automation.

scientific article published on 31 October 2008

Practical aspects of the SAMPL challenge: providing an extensive experimental data set for the modeling community

scientific article

Predicting the Effect of Chemical Factors on the pH of Crystallization Trials

scientific article published on 30 May 2020

Rational engineering of a mesohalophilic carbonic anhydrase to an extreme halotolerant biocatalyst.

scientific article

Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction

article

Some of the most interesting CASP11 targets through the eyes of their authors

scientific article

Some practical guidelines for UV imaging in the protein crystallization laboratory

scientific article published on 26 January 2013

Structural analysis of a set of proteins resulting from a bacterial genomics project.

scientific article

Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses

scientific article

Structural and biochemical characterization of the biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841.

scientific article published on 9 February 2018

Structural and functional characterisation of ferret interleukin-2

scientific article

Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design

scientific article

Structural basis for ligand recognition by a Cache chemosensory domain that mediates carboxylate sensing in Pseudomonas syringae

scientific article (publication date: 13 October 2016)

Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus.

scientific article

Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor ⬇️

scientific article published on January 19, 2012

Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus

scientific article

Structures of the transcriptional regulator BgaR, a lactose sensor

scientific article published on 26 June 2019

Taking biological structure communications into the third dimension

scientific article published on 05 November 2019

Tapping the Protein Data Bank for crystallization information

scientific article published on 19 November 2005

The DINGO dataset: a comprehensive set of data for the SAMPL challenge

scientific article

The X-ray crystal structure of the N-terminal domain of Ssr4, a Schizosaccharomyces pombe chromatin-remodelling protein

scientific article published on 25 November 2020

The evolving story of AtzT, a periplasmic binding protein

scientific article published on 31 October 2019

The nanoscience behind the art of in-meso crystallization of membrane proteins

scientific article

The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum

scientific article published on 29 February 2008

The structure of the hexameric atrazine chlorohydrolase AtzA

scientific article

The structure of vanin 1: a key enzyme linking metabolic disease and inflammation

scientific article

Towards rationalization of crystallization screening for small- to medium-sized academic laboratories: the PACT/JCSG+ strategy

scientific article published on 28 September 2005

Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly.

scientific article published on 14 May 2015

X-Ray Structure and Mutagenesis Studies of the N-Isopropylammelide Isopropylaminohydrolase, AtzC

scientific article

X-ray crystal structure of a malonate-semialdehyde dehydrogenase from Pseudomonas sp. strain AAC.

scientific article published in January 2017

X-ray structure of the amidase domain of AtzF, the allophanate hydrolase from the cyanuric acid-mineralizing multienzyme complex

scientific article

List of works by Janet Newman

300-Fold Increase in Production of the Zn2+-Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme Stabilization

A Nondenaturing Purification Scheme for the DNA-Binding Domain of Poly(ADP-Ribose) Polymerase, a Structure-Specific DNA-Binding Protein ⬇️

A drunken search in crystallization space

A new crystal form of human vascular adhesion protein 1

A novel decarboxylating amidohydrolase involved in avoiding metabolic dead ends during cyanuric acid catabolism in Pseudomonas sp. strain ADP

A universal indicator dye pH assay for crystallization solutions and other high-throughput applications

An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme.

BLASTing away preconceptions in crystallization trials

Cinder: keeping crystallographers app-y

Classification of crystallization outcomes using deep convolutional neural networks.

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera

Contamination or serendipity - doing the wrong thing by chance

Crystal Structure of an Indole-3-Acetic Acid Amido Synthetase from Grapevine Involved in Auxin Homeostasis ⬇️

Crystal structure of a putrescine aminotransferase from Pseudomonas sp. strain AAC.

Crystal structures of human ENPP1 in apo and bound forms

Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site

Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.

Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate

Crystallization and preliminary X-ray analysis of the complexes between a Fab and two forms of human insulin-like growth factor II.

Crystallization and preliminary X-ray diffraction analysis of the amidase domain of allophanate hydrolase from Pseudomonas sp. strain ADP.

Crystallization of an apo form of human arginase: using all the tools in the toolbox simultaneously

Crystallization reports are the backbone of Acta Cryst. F, but do they have any spine?

Crystallization screening: the influence of history on current practice.

Crystallization: digging into the past to learn lessons for the future.

Cyanuric acid hydrolase: evolutionary innovation by structural concatenation

Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices

Determination of the Structure of the Catabolic N-Succinylornithine Transaminase (AstC) from Escherichia coli

Evaluating Protic Ionic Liquids as Protein Crystallization Additives

Expanding screening space through the use of alternative reservoirs in vapor-diffusion experiments

Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography

Formulation screening by differential scanning fluorimetry: how often does it work?

Fragment screening for a protein-protein interaction inhibitor to WDR5

From information management to protein annotation: preparing protein structures for drug discovery.

Germline humanization of a murine Aβ antibody and crystal structure of the humanized recombinant Fab fragment

Haloalkane dehalogenases: structure of a Rhodococcus enzyme

High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.

High-Throughput Production and Structural Characterization of Libraries of Self-Assembly Lipidic Cubic Phase Materials ⬇️

High-throughput thermal scanning for protein stability: making a good technique more robust.

Identification and characterization of two families of F420H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation

Identifying, studying and making good use of macromolecular crystals.

Improved success of sparse matrix protein crystallization screening with heterogeneous nucleating agents

Initial evaluations of the reproducibility of vapor-diffusion crystallization

Innovation versus practice in biological crystallization

Interrogating HIV integrase for compounds that bind- a SAMPL challenge

Introducing Methods Communications, a new category of contributions to Acta Crystallographica F

Lipidic Cubic Phase-Induced Membrane Protein Crystallization: Interplay Between Lipid Molecular Structure, Mesophase Structure and Properties, and Crystallogenesis

Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2

Meltdown: A Tool to Help in the Interpretation of Thermal Melt Curves Acquired by Differential Scanning Fluorimetry

Nitrate in the active site of protein tyrosine phosphatase 1B is a putative mimetic of the transition state

Novel buffer systems for macromolecular crystallization

On the need for an international effort to capture, share and use crystallization screening data

One plate, two plates, a thousand plates. How crystallisation changes with large numbers of samples.

Parallel and antiparallel cyclic d/l peptide nanotubes.

Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?

Phoenito experiments: combining the strengths of commercial crystallization automation.

Practical aspects of the SAMPL challenge: providing an extensive experimental data set for the modeling community

Predicting the Effect of Chemical Factors on the pH of Crystallization Trials

Rational engineering of a mesohalophilic carbonic anhydrase to an extreme halotolerant biocatalyst.

Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction

Some of the most interesting CASP11 targets through the eyes of their authors

Some practical guidelines for UV imaging in the protein crystallization laboratory

Structural analysis of a set of proteins resulting from a bacterial genomics project.

Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses

Structural and biochemical characterization of the biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841.

Structural and functional characterisation of ferret interleukin-2

Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design

Structural basis for ligand recognition by a Cache chemosensory domain that mediates carboxylate sensing in Pseudomonas syringae

Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus.

Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor ⬇️

Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus

Structures of the transcriptional regulator BgaR, a lactose sensor

Taking biological structure communications into the third dimension

Tapping the Protein Data Bank for crystallization information

The DINGO dataset: a comprehensive set of data for the SAMPL challenge

The X-ray crystal structure of the N-terminal domain of Ssr4, a Schizosaccharomyces pombe chromatin-remodelling protein