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List of works by Xinhua Ji

A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin.

scientific article published on 27 September 2017

A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms ⬇️

scientific article published on May 9, 2013

A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins

scientific article published on 15 November 2005

A spring-loaded state of NusG in its functional cycle is suggested by X-ray crystallography and supported by site-directed mutants

scientific article (publication date: 4 March 2003)

A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation

scientific article published on 08 December 2021

Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(

scientific article published on 01 June 1997

Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons

scientific article published in September 1997

Allosteric Activation of Bacterial Swi2/Snf2 (Switch/Sucrose Non-fermentable) Protein RapA by RNA Polymerase: BIOCHEMICAL AND STRUCTURAL STUDIES.

scientific article

Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78

scientific article

Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine

scientific article

Alpha-subunit oxidation in T-state crystals of a sebacyl cross-linked human hemoglobin with unusual autoxidation properties

scientific article

Amino acid substitutions at positions 207 and 221 contribute to catalytic differences between murine glutathione S-transferase Al-1 and A2-2 toward (+)-anti-7,8-dihydroxy-9,10-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene

scientific article published on 01 August 1999

Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

scientific article published on July 2006

Biochemical and biological studies of mouse APOBEC3.

scientific article published on 22 January 2014

Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties

scientific article

Catalytic center assembly of HPPK as revealed by the crystal structure of a ternary complex at 1.25 A resolution

scientific article

Catalytic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: site-directed mutagenesis and biochemical studies.

scientific article published in February 2003

Characterization of four orthologs of stringent starvation protein A.

scientific article published on 25 April 2003

Chemical transformation is not rate-limiting in the reaction catalyzed by Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.

scientific article published in July 2002

Crystal structure of ERA: a GTPase-dependent cell cycle regulator containing an RNA binding motif

scientific article

Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimic acid and an ATP analogue

scientific article published on 01 July 2006

Crystal structure of a plectonemic RNA supercoil

scientific article

Crystal structure of apo-cellular retinoic acid-binding protein type II (R111M) suggests a mechanism of ligand entry ⬇️

scientific article published on May 8, 1998

Crystal structure of the broadly cross-reactive HIV-1-neutralizing Fab X5 and fine mapping of its epitope

scientific article

Crystallization and preliminary X-ray diffraction analysis of shikimate kinase from Mycobacterium tuberculosis in complex with MgADP.

scientific article published on 21 November 2001

Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage

scientific article

Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase.

scientific article

Crystallographic, molecular modeling, and biophysical characterization of the valine beta 67 (E11)-->threonine variant of hemoglobin

scientific article

Design, synthesis, and anticancer activity evaluation of irreversible allosteric inhibitors of the ubiquitin-conjugating enzyme Ube2g2

scientific article published on 20 August 2018

Dissecting the nucleotide binding properties of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase with fluorescent 3'(2)'-o-anthraniloyladenosine 5'-triphosphate.

scientific article

Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: crystallographic studies

scientific article (publication date: 18 February 2003)

Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin

scientific article published on 02 December 2013

Human carboxyhemoglobin at 2.2 A resolution: structure and solvent comparisons of R-state, R2-state and T-state hemoglobins

scientific article

Impact of antibody framework residue VH-71 on the stability of a humanised anti-MUC1 scFv and derived immunoenzyme.

scientific article published on May 2004

Impact of low-frequency hotspot mutation R282Q on the structure of p53 DNA-binding domain as revealed by crystallography at 1.54 Å resolution

scientific article

Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.

scientific article

Intermediate states of ribonuclease III in complex with double-stranded RNA.

scientific article published on October 2005

Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical

scientific article published on 29 September 2016

Location of a potential transport binding site in a sigma class glutathione transferase by x-ray crystallography

scientific article

Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxide of chrysene.

scientific article published on September 1997

Modular mutagenesis of exons 1, 2, and 8 of a glutathione S-transferase from the mu class. Mechanistic and structural consequences for chimeras of isoenzyme 3-3

scientific article published on 01 October 1992

New ways to derivatize at position 6 of 7,7-dimethyl-7,8-dihydropterin

scientific article published on November 2011

Nitric oxide (NO) releasing poly ADP-ribose polymerase 1 (PARP-1) inhibitors targeted to glutathione S-transferase P1-overexpressing cancer cells

scientific article published on 25 February 2014

PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.

scientific article published on February 2006

Positive and negative cooperativities at subsequent steps of oxygenation regulate the allosteric behavior of multistate sebacylhemoglobin

scientific article

Purification, characterization and crystallization of ERA, an essential GTPase from Escherichia coli

scientific article published on 01 February 1999

RNase III: Genetics and function; structure and mechanism

scientific article

Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.

scientific article published in March 2004

Redesign of a four-helix bundle protein by phage display coupled with proteolysis and structural characterization by NMR and X-ray crystallography

scientific article

Residue R216 and catalytic efficiency of a murine class alpha glutathione S-transferase toward benzo[a]pyrene 7(R),8(S)-diol 9(S), 10(R)-epoxide

scientific article

Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide

scientific article

Role of arginine 216 in catalytic activity of murine Alpha class glutathione transferases mGSTAl-1 and mGSTA2-2 toward carcinogenic diol epoxides of polycyclic aromatic hydrocarbons.

scientific article published in August 2001

Role of protein conformational dynamics in the catalysis by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

scientific article

Snapshots along the reaction coordinate of an SNAr reaction catalyzed by glutathione transferase

scientific article

Structural Basis for Binding of RNA and Cofactor by a KsgA Methyltransferase

scientific article

Structural Basis for the Aldolase and Epimerase Activities of Staphylococcus aureus Dihydroneopterin Aldolase

scientific article

Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism

scientific article

Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination

scientific article

Structural basis for the function of stringent starvation protein a as a transcription factor.

scientific article published on 25 February 2005

Structural enzymology and inhibition of the bi-functional folate pathway enzyme HPPK-DHPS from the biowarfare agent Francisella tularensis

scientific article

Structural insight into the mechanism of double-stranded RNA processing by ribonuclease III.

scientific article

Structural mimicry of CD4 by a cross-reactive HIV-1 neutralizing antibody with CDR-H2 and H3 containing unique motifs.

scientific article published on 9 January 2006

Structure and Function of the Xenobiotic Substrate-Binding Site and Location of a Potential Non-Substrate-Binding Site in a Class π Glutathione S-Transferase, ⬇️

scientific article published on August 12, 1997

Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori

scientific article published on 02 November 2019

Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics

scientific article

Structure and dynamics of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.

scientific article published in January 2001

Structure and function of RapA: A bacterial Swi2/Snf2 protein required for RNA polymerase recycling in transcription ⬇️

scientific article published on March 16, 2011

Structure and function of Rnt1p: An alternative to RNAi for targeted RNA degradation

scientific article published on 11 December 2018

Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1

scientific article

Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene

scientific article

Structure and intramolecular hydrogen bonding of 1-phenazinecarboxylic acid ⬇️

scientific article published on January 15, 1992

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes

scientific article

Structure of 1,1-dichloro-2-(4-methoxyphenyl)-2,3-diphenylcyclopropane

scientific article published on 01 May 1992

Structure of ERA in complex with the 3' end of 16S rRNA: Implications for ribosome biogenesis

scientific article

Structure of a Eukaryotic RNase III Postcleavage Complex Reveals a Double-Ruler Mechanism for Substrate Selection

scientific article

Structure of an isolated unglycosylated antibody CH2 domain

scientific article

Structure of asperketal B

scientific article published on 01 May 1992

Structure of lansimide 2, a product from Clausena lansium

scientific article published on 01 June 1992

Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody

scientific article published on 5 April 2006

Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.

scientific article

Survival of BRCA2-Deficient Cells Is Promoted by GIPC3, a Novel Genetic Interactor of BRCA2.

scientific article

Switching protein-DNA recognition specificity by single-amino-acid substitutions in the P1 par family of plasmid partition elements

scientific article

Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs.

scientific article published on 30 September 2008

The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA

scientific article

The Functional Cycle of Rnt1p: Five Consecutive Steps of Double-Stranded RNA Processing by a Eukaryotic RNase III.

scientific article published on 11 January 2017

The absorption edge of protein-bound mercury and a double-edge strategy for HgMAD data acquisition.

scientific article

The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X

scientific article published on 12 July 2019

The molecular mechanism of dsRNA processing by a bacterial Dicer

scientific article published on 01 May 2019

The three-dimensional structure of a glutathione S-transferase from the mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2-A resolution

scientific article published on October 27, 1992

Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer

scientific article published on 20 July 2018

Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods

scientific article

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