List of works - Marek Minarik

A novel high-resolution chipCE assay for rapid detection of EGFR gene mutations and amplifications in lung cancer therapy by a combination of fragment analysis, denaturing CE and MLPA.

scientific article published in October 2010

Acquired resistance of pulmonary adenocarcinoma to initially successful targeted therapy due to EGFR mutation T790M

scientific article published on 01 July 2007

Analysis of genetic events in 17p13 and 9p21 regions supports predominant monoclonal origin of multifocal and recurrent bladder cancer

scientific article published on 15 December 2005

Application of cycling gradient capillary electrophoresis to detection of APC, K-ras, and DCC point mutations in patients with sporadic colorectal tumors.

scientific article

Application of denaturing capillary electrophoresis for the detection of prognostic mutations in isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 genes in brain tumors.

scientific article

Application of high-resolution capillary array electrophoresis with automated fraction collection for GeneCalling trade mark analysis of the yeast genomic DNA.

scientific article

Assembly of a large Y-STR haplotype database for the Czech population and investigation of its substructure

scientific article

Capillary Electrophoresis and its Basic Principles in Historical Retrospect Part 1. The Early Decades of the “Long Nineteenth Century”: The Voltaic Pile, and the Discovery of Electrolysis, Electrophoresis and Electroosmosis

scholarly article published on Substantia in 2021

Change in Serum Lactate Dehydrogenase Is Associated with Outcome of Patients with Advanced-stage NSCLC Treated with Erlotinib

scientific article

Clinical significance of hypermethylation status in NSCLC: evaluation of a 30-gene panel in patients with advanced disease.

scientific article

Colorectal cancer prevention in the Czech Republic

scientific article published on 01 January 2014

Colorectal cancer screening: 20 years of development and recent progress

scientific article

Comparison of EGFR-TKI and chemotherapy in the first-line treatment of advanced EGFR mutation-positive NSCLC.

scientific article published in January 2013

Comparison of Native Aspirates and Cytological Smears Obtained by EUS-Guided Biopsies for Effective DNA/RNA Marker Testing in Pancreatic Cancer

scientific article published on 25 October 2018

Cycling gradient capillary electrophoresis: a low-cost tool for high-throughput analysis of genetic variations

scientific article published on 01 June 2003

Denaturing capillary electrophoresis for automated detection of L858R mutation in exon 21 of the epidermal growth factor receptor gene in prediction of the outcome of lung cancer therapy.

scientific article published on August 2010

Design of a fraction collector for capillary array electrophoresis

scientific article published on 01 January 2002

Dominance of EGFR and insignificant KRAS mutations in prediction of tyrosine-kinase therapy for NSCLC patients stratified by tumor subtype and smoking status.

scientific article published in July 2009

Epidermal Growth Factor Receptor Gene Amplification in Patients with Advanced-stage NSCLC.

scientific article

Erlotinib in the treatment of advanced squamous cell NSCLC.

scientific article

Evaluation of clinical relevance of examining K-ras, p16 and p53 mutations along with allelic losses at 9p and 18q in EUS-guided fine needle aspiration samples of patients with chronic pancreatitis and pancreatic cancer

scientific article (publication date: 21 July 2007)

Extraordinary response to erlotinib therapy in a patient with lung adenocarcinoma exhibiting KRAS mutation and EGFR amplification.

scientific article published in May 2011

Fraction collection in micropreparative capillary zone electrophoresis and capillary isoelectric focusing

scientific article published on 01 January 2000

Gene mutations in squamous cell NSCLC: insignificance of EGFR, KRAS and PIK3CA mutations in prediction of EGFR-TKI treatment efficacy

scientific article published on April 1, 2013

Genetic testing in the management of relatives of patients with hypertrophic cardiomyopathy

scientific article published on January 2014

High serum level of C-reactive protein is associated with worse outcome of patients with advanced-stage NSCLC treated with erlotinib.

scientific article published on 19 June 2015

IDH1/2 Mutation and MGMT Promoter Methylation - the Relevant Survival Predictors in Czech Patients with Brain Gliomas

scientific article published on January 2016

Lack of association between clopidogrel responsiveness tested using point-of-care assay and prognosis of patients with coronary artery disease.

scientific article

Longitudinal molecular characterization of endoscopic specimens from colorectal lesions

scientific article published on May 2016

MicroRNAs in Pancreatic Cancer: Involvement in Carcinogenesis and Potential Use for Diagnosis and Prognosis.

scientific article published on 19 April 2015

Monitoring of Circulating Tumor Cells by a Combination of Immunomagnetic Enrichment and RT-PCR in Colorectal Cancer Patients Undergoing Surgery

scientific article published in November 2016

Multicapillary electrophoresis of unlabeled DNA fragments with high-sensitive laser-induced fluorescence detection by counter-current migration of intercalation dye.

scientific article published in November 2005

Mutation-based detection and monitoring of cell-free tumor DNA in peripheral blood of cancer patients

scientific article published on 28 June 2012

P18. Predictive role of serum tumor markers NSE and TK in patients with advanced-stage NSCLC treated with EGFR-TKIs.

scientific article

P20. The role of statins in patients with advanced NSCLC harboring KRAS mutation treated with EGFR-TKIs.

scientific article published in October 2014

Parallel optimization and genotyping of multiple single-nucleotide polymorphism markers by sample pooling approach using cycling-gradient CE with multiple injections

scientific article published on 01 October 2006

Pemetrexed Versus Erlotinib in the Second-line Treatment of Patients with Advanced-stage Non-squamous NSCLC Harboring Wild-type EGFR Gene

scientific article published on January 2016

Predictive and prognostic significance of sodium levels in patients with NSCLC treated by erlotinib.

scientific article published on December 2014

Predictive role of CEA and CYFRA 21-1 in patients with advanced-stage NSCLC treated with erlotinib

Prognostic Importance of Cell Cycle Regulators Cyclin D1 (CCND1) and Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B/p27) in Sporadic Gastric Cancers.

scientific article published on 03 October 2016

Rapid testing of clopidogrel resistance by genotyping of CYP2C19 and CYP2C9 polymorphisms using denaturing on-chip capillary electrophoresis.

scientific article published in April 2012

Second line treatment in advanced non-small cell lung cancer (NSCLC): comparison of efficacy of erlotinib and chemotherapy

scientific article published on 01 January 2013

Serum Concentration of Erlotinib and its Correlation with Outcome and Toxicity in Patients with Advanced-stage NSCLC.

scientific article

Serum albumin is a strong predictor of survival in patients with advanced-stage non-small cell lung cancer treated with erlotinib

scientific article published on 8 March 2016

Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA

scientific article published on 01 December 2019

Skin rash as useful marker of erlotinib efficacy in NSCLC and its impact on clinical practice.

scientific article published in January 2013

Somatic TP53 mutation mosaicism in a patient with Li-Fraumeni syndrome

scientific article published on 01 February 2009

Statins augment efficacy of EGFR-TKIs in patients with advanced-stage non-small cell lung cancer harbouring KRAS mutation.

scientific article published on 22 February 2015

The Prognostic Role of KRAS Mutation in Patients with Advanced NSCLC Treated with Second- or Third-line Chemotherapy

scientific article published on March 2016

The dominant role of G12C over other KRAS mutation types in the negative prediction of efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer.

scientific article

The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review of the literature

scientific article published on 22 June 2016

The role of neuron-specific enolase (NSE) and thymidine kinase (TK) levels in prediction of efficacy ofEGFR-TKIs in patients with advanced-stage NSCLC [corrected].

scientific article published in September 2014

Toward male individualization with rapidly mutating y-chromosomal short tandem repeats

scientific article

Two-point fluorescence detection and automated fraction collection applied to constant denaturant capillary electrophoresis

scientific article published on 01 September 2000

Ultrafast DNA analysis by capillary electrophoresis/laser-induced fluorescence detection.

scientific article

Utility of a panel of gene mutations and amplifications for estimation of prognosis in patients with gastric cancer

article

Utility of cell-free tumour DNA for post-surgical follow-up of colorectal cancer patients

scientific article published on 01 May 2012

Variants in miRNA Regulating Cardiac Growth Are Not a Common Cause of Hypertrophic Cardiomyopathy

scientific article published on 24 January 2015

[EGFR mutations in patients with advanced NSCLC].

scientific article published in January 2012

List of works by Marek Minarik

A novel high-resolution chipCE assay for rapid detection of EGFR gene mutations and amplifications in lung cancer therapy by a combination of fragment analysis, denaturing CE and MLPA.

Acquired resistance of pulmonary adenocarcinoma to initially successful targeted therapy due to EGFR mutation T790M

Analysis of genetic events in 17p13 and 9p21 regions supports predominant monoclonal origin of multifocal and recurrent bladder cancer

Application of cycling gradient capillary electrophoresis to detection of APC, K-ras, and DCC point mutations in patients with sporadic colorectal tumors.

Application of denaturing capillary electrophoresis for the detection of prognostic mutations in isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 genes in brain tumors.

Application of high-resolution capillary array electrophoresis with automated fraction collection for GeneCalling trade mark analysis of the yeast genomic DNA.

Assembly of a large Y-STR haplotype database for the Czech population and investigation of its substructure

Capillary Electrophoresis and its Basic Principles in Historical Retrospect Part 1. The Early Decades of the “Long Nineteenth Century”: The Voltaic Pile, and the Discovery of Electrolysis, Electrophoresis and Electroosmosis

Change in Serum Lactate Dehydrogenase Is Associated with Outcome of Patients with Advanced-stage NSCLC Treated with Erlotinib

Clinical significance of hypermethylation status in NSCLC: evaluation of a 30-gene panel in patients with advanced disease.

Colorectal cancer prevention in the Czech Republic

Colorectal cancer screening: 20 years of development and recent progress

Comparison of EGFR-TKI and chemotherapy in the first-line treatment of advanced EGFR mutation-positive NSCLC.

Comparison of Native Aspirates and Cytological Smears Obtained by EUS-Guided Biopsies for Effective DNA/RNA Marker Testing in Pancreatic Cancer

Cycling gradient capillary electrophoresis: a low-cost tool for high-throughput analysis of genetic variations

Denaturing capillary electrophoresis for automated detection of L858R mutation in exon 21 of the epidermal growth factor receptor gene in prediction of the outcome of lung cancer therapy.

Design of a fraction collector for capillary array electrophoresis

Dominance of EGFR and insignificant KRAS mutations in prediction of tyrosine-kinase therapy for NSCLC patients stratified by tumor subtype and smoking status.

Epidermal Growth Factor Receptor Gene Amplification in Patients with Advanced-stage NSCLC.

Erlotinib in the treatment of advanced squamous cell NSCLC.

Evaluation of clinical relevance of examining K-ras, p16 and p53 mutations along with allelic losses at 9p and 18q in EUS-guided fine needle aspiration samples of patients with chronic pancreatitis and pancreatic cancer

Extraordinary response to erlotinib therapy in a patient with lung adenocarcinoma exhibiting KRAS mutation and EGFR amplification.

Fraction collection in micropreparative capillary zone electrophoresis and capillary isoelectric focusing

Gene mutations in squamous cell NSCLC: insignificance of EGFR, KRAS and PIK3CA mutations in prediction of EGFR-TKI treatment efficacy

Genetic testing in the management of relatives of patients with hypertrophic cardiomyopathy

High serum level of C-reactive protein is associated with worse outcome of patients with advanced-stage NSCLC treated with erlotinib.

IDH1/2 Mutation and MGMT Promoter Methylation - the Relevant Survival Predictors in Czech Patients with Brain Gliomas

Lack of association between clopidogrel responsiveness tested using point-of-care assay and prognosis of patients with coronary artery disease.

Longitudinal molecular characterization of endoscopic specimens from colorectal lesions

MicroRNAs in Pancreatic Cancer: Involvement in Carcinogenesis and Potential Use for Diagnosis and Prognosis.

Monitoring of Circulating Tumor Cells by a Combination of Immunomagnetic Enrichment and RT-PCR in Colorectal Cancer Patients Undergoing Surgery

Multicapillary electrophoresis of unlabeled DNA fragments with high-sensitive laser-induced fluorescence detection by counter-current migration of intercalation dye.

Mutation-based detection and monitoring of cell-free tumor DNA in peripheral blood of cancer patients

P18. Predictive role of serum tumor markers NSE and TK in patients with advanced-stage NSCLC treated with EGFR-TKIs.

P20. The role of statins in patients with advanced NSCLC harboring KRAS mutation treated with EGFR-TKIs.

Parallel optimization and genotyping of multiple single-nucleotide polymorphism markers by sample pooling approach using cycling-gradient CE with multiple injections

Pemetrexed Versus Erlotinib in the Second-line Treatment of Patients with Advanced-stage Non-squamous NSCLC Harboring Wild-type EGFR Gene

Predictive and prognostic significance of sodium levels in patients with NSCLC treated by erlotinib.

Predictive role of CEA and CYFRA 21-1 in patients with advanced-stage NSCLC treated with erlotinib

Prognostic Importance of Cell Cycle Regulators Cyclin D1 (CCND1) and Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B/p27) in Sporadic Gastric Cancers.

Rapid testing of clopidogrel resistance by genotyping of CYP2C19 and CYP2C9 polymorphisms using denaturing on-chip capillary electrophoresis.

Second line treatment in advanced non-small cell lung cancer (NSCLC): comparison of efficacy of erlotinib and chemotherapy

Serum Concentration of Erlotinib and its Correlation with Outcome and Toxicity in Patients with Advanced-stage NSCLC.

Serum albumin is a strong predictor of survival in patients with advanced-stage non-small cell lung cancer treated with erlotinib

Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA

Skin rash as useful marker of erlotinib efficacy in NSCLC and its impact on clinical practice.

Somatic TP53 mutation mosaicism in a patient with Li-Fraumeni syndrome

Statins augment efficacy of EGFR-TKIs in patients with advanced-stage non-small cell lung cancer harbouring KRAS mutation.

The Prognostic Role of KRAS Mutation in Patients with Advanced NSCLC Treated with Second- or Third-line Chemotherapy

The dominant role of G12C over other KRAS mutation types in the negative prediction of efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer.

The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review of the literature

The role of neuron-specific enolase (NSE) and thymidine kinase (TK) levels in prediction of efficacy ofEGFR-TKIs in patients with advanced-stage NSCLC [corrected].

Toward male individualization with rapidly mutating y-chromosomal short tandem repeats

Two-point fluorescence detection and automated fraction collection applied to constant denaturant capillary electrophoresis

Ultrafast DNA analysis by capillary electrophoresis/laser-induced fluorescence detection.

Utility of a panel of gene mutations and amplifications for estimation of prognosis in patients with gastric cancer

Utility of cell-free tumour DNA for post-surgical follow-up of colorectal cancer patients

Variants in miRNA Regulating Cardiac Growth Are Not a Common Cause of Hypertrophic Cardiomyopathy

[EGFR mutations in patients with advanced NSCLC].

[KRAS mutation assay on EUS-FNA specimens from pacients with pancreatic mass]