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List of works by Patrick Bulau

Affinity purification of erythropoietin from cell culture supernatant combined with MALDI-TOF-MS analysis of erythropoietin N-glycosylation.

scientific article published on 13 July 2017

Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA

scientific article published in January 2007

Analytical protein a chromatography as a quantitative tool for the screening of methionine oxidation in monoclonal antibodies.

scientific article published on 16 August 2012

Application of Hydrogen/Deuterium Exchange-Mass Spectrometry to Biopharmaceutical Development Requirements: Improved Sensitivity to Detection of Conformational Changes

scientific article published on 12 July 2017

Applying mini-bore HPAEC-MS/MS for the characterization and quantification of Fc N-glycans from heterogeneously glycosylated IgGs.

scientific article published on 9 August 2016

Assessment of chemical modifications of sites in the CDRs of recombinant antibodies: Susceptibility vs. functionality of critical quality attributes

scientific article published on 17 January 2014

Assessment of susceptible chemical modification sites of trastuzumab and endogenous human immunoglobulins at physiological conditions

scientific article published on 05 April 2018

Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics

scientific article published on 24 July 2019

Characterization of a molt-inhibiting hormone (MIH) of the crayfish, Orconectes limosus, by cDNA cloning and mass spectrometric analysis

scientific article published on 13 April 2005

Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles--part 1: separation-based methods

scientific article

Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles-Part 2: Mass spectrometric methods

scientific article published on July 2015

Detailed Characterization of Monoclonal Antibody Receptor Interaction Using Affinity Liquid Chromatography Hyphenated to Native Mass Spectrometry.

scientific article published on 11 April 2017

Detection of a phosphorylated glycine-serine linker in an IgG-based fusion protein.

scientific article published on 23 September 2016

Effects of sialic acid linkage on antibody-fragment crystallizable receptor binding and antibody dependent cytotoxicity depend on levels of fucosylation/bisecting

scientific article published on 01 August 2019

Extensive Chemical Modifications in the Primary Protein Structure of IgG1 Subvisible Particles Are Necessary for Breaking Immune Tolerance.

scientific article

Functional role and species-specific contribution of arginases in pulmonary fibrosis

scientific article published on 12 October 2007

High-throughput glycosylation analysis of therapeutic immunoglobulin G by capillary gel electrophoresis using a DNA analyzer

scientific article

High-throughput work flow for IgG Fc-glycosylation analysis of biotechnological samples

article published in 2012

Identification and monitoring of host cell proteins by mass spectrometry combined with high performance immunochemistry testing

scientific article (publication date: 2013)

Identification of neuropeptides from the sinus gland of the crayfish Orconectes limosus using nanoscale on-line liquid chromatography tandem mass spectrometry.

scientific article published on 22 February 2004

Identification of potential sites for tryptophan oxidation in recombinant antibodies using tert-butylhydroperoxide and quantitative LC-MS

scientific article

In vitro glycoengineering of IgG1 and its effect on Fc receptor binding and ADCC activity

scientific article

Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases

scientific journal article

Lung dendritic cells elicited by Fms-like tyrosine 3-kinase ligand amplify the lung inflammatory response to lipopolysaccharide.

scientific article published on 9 August 2007

Multi-Attribute Monitoring of Complex Erythropoetin Beta Glycosylation by GluC Liquid Chromatography-Mass Spectrometry Peptide Mapping

scientific article published on 19 May 2020

Pyroglutamyl peptidase type I from Trypanosoma brucei: a new virulence factor from African trypanosomes that de-blocks regulatory peptides in the plasma of infected hosts

scientific article published in March 2006

Quantitative assessment of arginine methylation in free versus protein-incorporated amino acids in vitro and in vivo using protein hydrolysis and high-performance liquid chromatography

scientific article published on 01 March 2006

Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule

scientific article published on 25 May 2015

Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperatures

scientific article

Subcellular fractionation of TGF-beta1-stimulated lung epithelial cells: a novel proteomic approach for identifying signaling intermediates.

scientific article

Tropolysin, a new oligopeptidase from African trypanosomes

scientific article

Two genetic variants of the crustacean hyperglycemic hormone (CHH) from the Australian crayfish, Cherax destructor: detection of chiral isoforms due to posttranslational modification.

scientific article

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