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List of works by Sooryanarayana Varambally

A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer

scientific article published on September 2008

A polycomb repression signature in metastatic prostate cancer predicts cancer outcome

scientific article published on November 2007

A systems approach to model metastatic progression.

scientific article

ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease

scientific article

AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist

scientific article

ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors

scientific article published in 2022

Abstract 2795: An onco-protein axis linking polycomb repressive complex 2 and polycomb repressive complex 1 through miRNAs in cancer

Abstract 4188: The role of microRNA-101 as a master tumor suppressor in cancer

Abstract 953: Mechanistic rationale for inhibition of Poly(ADP-Ribose) Polymerase in ETS gene fusion positive prostate cancer

article

Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells

scientific article published on 08 March 2017

Amplified centrosomes may underlie aggressive disease course in pancreatic ductal adenocarcinoma

scientific article

An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

scientific article

An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer

scientific article

Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases

article

Antibody-based detection of ERG rearrangement-positive prostate cancer

scientific article

Autoantibody profiles reveal ubiquilin 1 as a humoral immune response target in lung adenocarcinoma

scientific article

Autoantibody signatures in prostate cancer

scientific article published in September 2005

Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction.

scientific article

Changes in differential gene expression because of warm ischemia time of radical prostatectomy specimens.

scientific article

Characterization of KRAS rearrangements in metastatic prostate cancer

scientific article published on June 2011

Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer.

scientific article

Characterization of glycine-N-acyltransferase like 1 (GLYATL1) in prostate cancer

scientific article published on 02 August 2019

Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer

scientific article

Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior

scientific article published on 6 September 2017

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

scientific article

Corrigendum: TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer

scientific article published on 24 February 2016

Defining aggressive prostate cancer using a 12-gene model

scientific article

Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer

scientific article

Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer

scientific article published on 01 June 2017

Differential proteomic alterations between localised and metastatic prostate cancer.

scientific article published on August 2006

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

scientific article published on August 2007

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

scientific article published on 8 February 2016

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells ⬇️

scientific article published on September 19, 2003

Effect of Epidermal Growth Factor Receptor Inhibitor Class in the Treatment of Head and Neck Cancer with Concurrent Radiochemotherapy In vivo

scientific article published on 01 April 2007

Enhancing the antitumor activity of ErbB blockade with histone deacetylase (HDAC) inhibition

scientific article published in February 2006

Erratum: Corrigendum: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

scientific article published in Nature

Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer

scientific article published on 22 August 2016

Expression and role of PAICS, a de novo purine biosynthetic gene in prostate cancer

article

Gene Expression Profiling of Advanced Penile Squamous Cell Carcinoma Receiving Cisplatin-based Chemotherapy Improves Prognostication and Identifies Potential Therapeutic Targets.

scientific article published on 27 August 2016

Genomic and Epigenomic Alterations in Cancer

scientific article published on July 2016

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

scientific article

Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer

scientific article

Induced chromosomal proximity and gene fusions in prostate cancer

scientific article

Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1.

scientific article published on 5 March 2008

Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.

scientific article published on 23 November 2011

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

article

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

scientific article

Loss of RUNX3 expression is an independent adverse prognostic factor in diffuse large B-cell lymphoma

scientific article published on 17 May 2016

Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer

article

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

scientific article

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression ⬇️

scientific article

MicroRNA-101 regulated transcriptional modulator SUB1 plays a role in prostate cancer

scientific article published on 06 June 2016

Molecular cross-talk between the TRAIL and interferon signaling pathways.

scientific article published on 24 October 2001

Natural antibodies sustain differentiation and maturation of human dendritic cells

scholarly article

Natural human polyreactive IgM induce apoptosis of lymphoid cell lines and human peripheral blood mononuclear cells.

scientific article published on March 2004

Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer

scientific article published in June 2004

Probabilistic model of the human protein-protein interaction network

article

Prostate Cancer Genomics: Progress and Promise

scientific article published on 12 June 2013

Prostate Cancer Imaging and Biomarkers Guiding Safe Selection of Active Surveillance

scientific article published on 30 October 2017

Prostate Cancer: An Update on Molecular Pathology with Clinical Implications

scholarly article by George J. Netto et al published December 2017 in European Urology Supplements

Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases

scientific article

RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease

scientific article

Re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. Eur Urol 2010;58:12-8.

scientific article published on 18 May 2010

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

scientific article

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

scientific article

Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer

scientific article

Role of dutasteride in pre-clinical ETS fusion-positive prostate cancer models

scientific article

Role of epidermal growth factor receptor degradation in gemcitabine-mediated cytotoxicity.

scientific article published on 4 December 2006

Role of the TMPRSS2-ERG gene fusion in prostate cancer

scientific article

Role of transcriptional corepressor CtBP1 in prostate cancer progression

scientific article

Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells

scientific article published on December 2006

TMPRSS2-ERG-mediated feed-forward regulation of wild-type ERG in human prostate cancers.

scientific article

TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer

scientific article

Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality ⬇️

scientific article published on April 7, 2011

Targeting the link between late pregnancy and breast cancer.

scientific article published on 31 December 2013

The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling.

scientific article published on 6 January 2015

The miR-124-prolyl hydroxylase P4HA1-MMP1 axis plays a critical role in prostate cancer progression

scientific article

The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer

scientific article published on 12 July 2010

The role of SPINK1 in ETS rearrangement-negative prostate cancers

scientific article

The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma

scientific article

Therapeutic targeting of SPINK1-positive prostate cancer

scientific article published on March 2011

Tomlins et al. reply

scientific article published in Nature

Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition.

scholarly article

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses.

scientific article published on 18 July 2017

Wnt receptor Frizzled 8 is a target of ERG in prostate cancer

scientific article published on 26 July 2018

alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer

scientific article

alpha-Methylacyl-CoA racemase: expression levels of this novel cancer biomarker depend on tumor differentiation

scientific article

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